CLINICAL-ENZYMOLOGY.pptx
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This document discusses clinical enzymology and the use of enzymes in clinical diagnosis and treatment. It notes that enzymes act as biocatalysts and deficiencies can cause metabolic issues. Enzymes have tissue and intracellular specificity indicating the organ involved in disease. Enzyme activity can be inhibited reversibly or irreversibly, which can be used clinically. Enzymes can also be produced in laboratories. The document discusses functional and non-functional plasma enzymes, isoenzymes classified by their composition into true isoenzymes, allo-isoenzymes, and hybrid isoenzymes, and the uses of enzymes in clinical fields like diagnosis, prognosis, and therapy.
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- 7. PRINCIPAL--- 1.Enzyme are biocatalyst nd catalyze the biochemical reaction.So defficiency cause the metabolic reaction eg lactose intolerence 2.BASIC PRINCIPAL: Every enzyme has got the tissue specificity nd intracelluiar locational specificity to catagorically indicate the organ involved in disease process 3.Enzymes activity can be inhibited reversibly nd irreversibly so this can be used for clinical application
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- 9. a) Fuctional:They have got the function in blood Concentration more in blood than plasma e,g Lipoprotein lipase(LPL) clotting factors b)Non functional:No function in plasma. concentration more in cell than plasma e,g SGPT,SGOT,LDH,CPK c)Common criteria:functionaly nd non fuctionaly they form nd come to plasma e,g cerulopasmin(transport protein for iron)S
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