3. Structure:
• C27H45 OH.
• Hydrocarbon tail.
• A ring structure region
with 4 hydrocarbon rings.
• Hydroxyl group .
4. Structure
Characteristics:
• Soluble in water.
• All steroids are made from cholesterol.
• Cholesterol is called “sterol”.
• Cholesterol can dissolve in fatty and oily
substances.
• Cholesterol is an amphipathic molecule.
• Cholesterol travels in the blood through
lipoproteins such as LDL and HDL.
5. There are two types of
cholesterol :
Dietary cholesterol.• Cholesterol (manufactured in
the body).
6. Cholesterol’s bad reputation
:
What’s the reason of
cholesterol bad
reputation?
Heart diseases.
The difference between the
“Good” and the “Bad”
lipoproteins”.
7.
8. Importance of
Cholesterol :
• Cell Membrane.
• Brain Tissue.
• Immune
system.
• Hormones.
• Nerves.
• Vitamin D.
• Bile salts.
9. Synthesis of
cholesterol :
3 molecules of Acetyl CoA (from
fatty acids oxidation )
Mevalonate
Isoprene intermediates
Squalene intermediates
Cholesterol