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Chemical
composition of DNA
MANSI
BSC Biotech Hons.
What all we will study is-
• History of DNA
• What is DNA?
• DNA structure
• DNA components
HISTORY
• DNA was discovered in 1869 by Swiss researcher Friedrich
Miescher, who was originally trying to study the composition
of lymphoid cells (white blood cells). Instead, he isolated a
new molecule he called nuclein (DNA with associated
proteins) from a cell nucleus.
WHAT IS DNA?
• •DNA [deoxyribonucleic acid] is a polymer of a
deoxyribonucleotide.
• • DNA or deoxyribonucleic acid is a long molecule
that contains our unique genetic code. Like a recipe
book, it holds the instructions for making all the
proteins in our bodies.
• DNA contain four basic building blocks or ‘bases’:
• adenine(A), cytosine (C), guanine (G) and thymine
(T).
• Each chain is formed by many
nucleotides{nucleotides= nitrogenous base +
pentose sugar + phosphate group} linked
together through phosphodiester bond.
• example- adenosine, cytidine etc.
• Nitrogenous bases are of four types-
Adenine, guanine, thymine, cytosine.
• Sugar present in DNA is deoxyribose sugar.
• Complementary bases pair with each other through a
hydrogen bond.
• Purines always pair with their corresponding
pyrimidine's. adenine pairs with thymine through 2- H
bonds while guanine pairs with cytosine through 3-H
bonds.
• In course of formation of a polynucleotide chain, a
phosphate group remains free at 5' end of a ribose sugar
and 1-OH group remains free at 3' end ribose.
THANK YOU

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Chemical composition of dna

  • 2. What all we will study is- • History of DNA • What is DNA? • DNA structure • DNA components
  • 3. HISTORY • DNA was discovered in 1869 by Swiss researcher Friedrich Miescher, who was originally trying to study the composition of lymphoid cells (white blood cells). Instead, he isolated a new molecule he called nuclein (DNA with associated proteins) from a cell nucleus.
  • 4. WHAT IS DNA? • •DNA [deoxyribonucleic acid] is a polymer of a deoxyribonucleotide. • • DNA or deoxyribonucleic acid is a long molecule that contains our unique genetic code. Like a recipe book, it holds the instructions for making all the proteins in our bodies. • DNA contain four basic building blocks or ‘bases’: • adenine(A), cytosine (C), guanine (G) and thymine (T).
  • 5. • Each chain is formed by many nucleotides{nucleotides= nitrogenous base + pentose sugar + phosphate group} linked together through phosphodiester bond. • example- adenosine, cytidine etc. • Nitrogenous bases are of four types- Adenine, guanine, thymine, cytosine. • Sugar present in DNA is deoxyribose sugar.
  • 6.
  • 7. • Complementary bases pair with each other through a hydrogen bond. • Purines always pair with their corresponding pyrimidine's. adenine pairs with thymine through 2- H bonds while guanine pairs with cytosine through 3-H bonds. • In course of formation of a polynucleotide chain, a phosphate group remains free at 5' end of a ribose sugar and 1-OH group remains free at 3' end ribose.
  • 8.