The nucleus is the control center of the cell and contains DNA. It is surrounded by a membrane. Ribosomes produce proteins and may be free in the cytoplasm or attached to the endoplasmic reticulum. The endoplasmic reticulum transports molecules through a series of membranes and may be rough or smooth. Mitochondria are the powerhouses of the cell and convert energy. Vacuoles store waste and other materials. Lysosomes break down materials as the cell's waste management system. Microtubules and microfilaments make up the cytoskeleton to support the cell.