Global Medical Cures™ | Sexually Transmitted Diseases (CDC Treatment Guidelines)
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Développement de méthodes rapides pour l'authentification des produits biolog...Pôle Qualiméditerranée
Kristian HOLST-LAURSEN, de la Faculté des sciences, Section plantes & sol, de l'Université de Copenhague (Danemark), revient sur les méthodes rapides pour l'authentification des produits, en s'arrêtant sur le projet Européen "AuthenticFood".
Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body.
is used to decrease pain and speed the healing of sores or blisters in people who have varicella (chickenpox)), herpes zoster
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Développement de méthodes rapides pour l'authentification des produits biolog...Pôle Qualiméditerranée
Kristian HOLST-LAURSEN, de la Faculté des sciences, Section plantes & sol, de l'Université de Copenhague (Danemark), revient sur les méthodes rapides pour l'authentification des produits, en s'arrêtant sur le projet Européen "AuthenticFood".
Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body.
is used to decrease pain and speed the healing of sores or blisters in people who have varicella (chickenpox)), herpes zoster
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Cefdinir and its role in otitis media, clinical study, indications, dosages, advantage, role of clavunalic acid, hepatotoxicity role all the research features are includes here to be prepared for Rajshahi Medical College, Focusing ENT specialist
Essential Drugs Dosage and Formulations (Medical Booklet Series by Dr. Aryan ...Dr. Aryan (Anish Dhakal)
This is the 22nd part of medical booklet series created by Dr. Aryan in order to familiarize doctors and medical students about the basic doses of drugs. Many students remember the mechanism of actions and other details of drug very well and regard doses as unnecessary. While you prescribe, this becomes one of the most important aspect. This study material is focused to resolve such issues.
Lipid Screening in Childhood for Detection of Multifactorial DyslipidemiaGlobal Medical Cures™
Lipid Screening in Childhood for Detection of Multifactorial Dyslipidemia
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www.globalmedicalcures.com
Skin Cancer Screening
IMPORTANT NOTE TO USERS OF WEBSITE & DOCUMENTS POSTED ON SLIDESHARE- Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
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Global Medical Cures™ | USA Chartbook on HealthCare for Blacks
IMPORTANT NOTE TO USERS OF WEBSITE & DOCUMENTS POSTED ON SLIDESHARE- Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
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Global Medical Cures™ | Older Americans- Key Indicators of Well Being Global Medical Cures™
Global Medical Cures™ | Older Americans- Key Indicators of Well Being
IMPORTANT NOTE TO USERS OF WEBSITE & DOCUMENTS POSTED ON SLIDESHARE- Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
www.globalmedicalcures.com
Global Medical Cures™ | Staggering Increase in Generic Drugs PricingGlobal Medical Cures™
Global Medical Cures™ | Staggering Increase in Generic Drugs Pricing
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Dangers & Consequences of Marijuana Abuse
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Harmful Interactions
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Medicines for Treating Depression
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Women & Depression
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | National Strategy for Combating Antibiotic Resistant ...Global Medical Cures™
Global Medical Cures™ | National Strategy for Combating Antibiotic Resistant Bacteria
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | PCAST Report- Combating Antibiotic ResistanceGlobal Medical Cures™
Global Medical Cures™ | PCAST Report- Combating Antibiotic Resistance
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Physical Activity Guidelines for Americans
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Dietary Guidelines for Americans
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Aging and your Eyes
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Help your Child gain control over Asthma
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Drugs approved for Bone Cancer
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Drugs approved for Breast Cancer
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™| Drugs approved for Head and Neck Cancer
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™ | Drugs approved for Non Hodgkin Lymphoma
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Global Medical Cures™| Drugs approved for Pancreatic Cancer
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Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
3. These summary guidelines reflect the August 2012 update to the 2010 CDC Guidelines for
Treatment of Sexually Transmitted Diseases. CDC issues new recommendations for treating
uncomplicated gonorrhea in this update.
This summary is intended as a source of clinical guidance. When more than one therapeutic
regimen is recommended the sequence is in alphabetical order unless the choices for therapy are
prioritized based on efficacy, cost, or convenience. The recommended regimens should be used
primarily; alternative regimens can be considered in instances of substantial drug allergy or other
contraindications. An important component of STD treatment is partner management. Providers
can arrange for the evaluation and treatment of sex partners either directly or with assistance
from state and local health departments.
Complete guidelines can be viewed online at www.cdc.gov/std/treatment/2010.
This booklet has been reviewed by the CDC 8/2012.
Indicates revision from the 2006 CDC Guidelines for the Treatment of Sexually Transmitted Diseases.
Indicates update from the 2010 CDC Guidelines for the Treatment of Sexually Transmitted Diseases; see MMWR
Morb Mortal Wkly Rep. 2012 Aug 10; 61(31):590-594 for details.
5. Bacterial Vaginosis
Recommended Rx Dose/Route Alternatives
Nonpregnant women metronidazole oral1
metronidazole gel 0.75%1
clindamycin cream 2%1,2
OR
OR
500 mg orally 2x/day for 7 days
One 5 g applicator intravaginally 1x/
day for 5 days
One 5 g applicator intravaginally at
bedtime for 7 days
tinidazole 2 g orally 1x/day for
2 days
tinidazole 1 g orally 1x/day for
5 days
clindamycin 300 mg orally 2x/day
for 7 days
clindamycin ovules 100 mg intravag-
inally at bedtime for 3 days
OR
OR
OR
Pregnancy3,4
metronidazole oral1
clindamycin oral
OR 500 mg orally 2x/day for 7 days or
250 mg orally 3x/day for 7 days
300 mg orally 2x/day for 7 days;
See complete guidelines for dosing
Bacterial
Vaginosis
6. Recommended Rx Dose/Route Alternatives
azithromycin
doxycycline6
OR 1 g orally in a single dose
100 mg orally 2x/day for 7 days
Cervicitis5
Cervicitis
7. Recommended Rx Dose/Route Alternatives
Adults, adolescents and chil-
dren aged >8 years
azithromycin
doxycycline6
OR 1 g orally in a single dose
100 mg orally 2x/day for 7 days
erythromycin base7
500 mg orally
4x/day for 7 days
erythromycin ethylsuccinate8
800 mg
orally 4x/day for 7 days
levofloxacin9
500 mg 1x/day orally
for 7 days
ofloxacin9
300 mg orally 2x/day for
7 days
OR
OR
OR
Pregnancy3
azithromycin10
amoxicillin
OR 1 g orally in a single dose
500 mg orally 3x/day for 7 days
erythromycin base7,11
500 mg orally
4x/day for 7 days
erythromycin base 250 mg orally 4x/
day for 14 days
erythromycin ethylsuccinate 800 mg
orally 4x/day for 7 days
erythromycin ethylsuccinate 400 mg
orally 4x/day for 14 days
OR
OR
OR
Children (<45 kg): urogenital,
rectal
erythromycin base12
or
ethylsuccinate
50 mg/kg/day orally (4 divided doses) daily for
14 days
Neonates: opthalmia neonato-
rum, pneumonia
erythromycin base12
or
ethylsuccinate
50 mg/kg/day orally (4 divided doses) daily for
14 days
Chlamydial Infections
Chlamydial
Infections
8. Recommended Rx Dose/Route Alternatives
For acute epididymitis
most likely due to
enteric organisms
or with negative GC
culture or NAAT:
ceftriaxone
doxycycline
levofloxacin
ofloxacin
PLUS
OR
250 mg IM in a single dose
100 mg orally 2x/day for 10 days
500 mg orally 1x/day for 10 days
300 mg orally 2x/day for 10 days
Epididymitis13,14
Epididymitis
9. Genital Herpes
Simplex
Recommended Rx Dose/Route Alternatives
First clinical episode of genital
herpes
acyclovir
acyclovir
famciclovir15
valacyclovir15
OR
OR
OR
400 mg orally 3x/day for 7-10 days16
200 mg orally 5x/day for 7-10 days16
250 mg orally 3x/day for 7-10 days16
1 g orally 2x/day for 7-10 days16
Episodic therapy for recurrent
genital herpes
acyclovir
acyclovir
acyclovir
famciclovir15
famciclovir15
famciclovir15
valacyclovir15
valacyclovir15
OR
OR
OR
OR
OR
OR
OR
400 mg orally 3x/day for 5 days
800 mg orally 2x/day for 5 days
800 mg orally 3x/day for 2 days
125 mg orally 2x/day for 5 days
1000 mg orally 2x/day for 1 day16
500 mg orally once, followed by 250 mg 2x/day
for 2 days
500 mg orally 2x/day for 3 days
1 g orally 1x/day for 5 days
Suppressive therapy17
for
recurrent genital herpes
acyclovir
famciclovir15
valacyclovir15
valacyclovir15
OR
OR
OR
400 mg orally 2x/day
250 mg orally 2x/day
500 mg orally once a day
1 g orally once a day
Recommended regimens for
episodic infection in persons
with HIV infection
acyclovir
famciclovir15
valacyclovir15
OR
OR
400 mg orally 3x/day for 5-10 days
500 mg orally 2x/day for 5-10 days
1 g orally 2x/day for 5-10 days
Recommended regimens for daily
suppressive therapy in persons
with HIV infection
acyclovir
famciclovir15
valacyclovir15
OR
OR
400-800 mg orally 2-3x/day
500 mg orally 2x/day
500 mg orally 2x/day
Genital Herpes Simplex
10. Genital Warts
(Human
Papillomavirus)
Recommended Rx Dose/Route Alternatives
External genital and perianal
warts
Patient Applied
podofilox 0.5%15
solution or gel
imiquimod 5%15
cream
sinecatechins 15% ointment2,15
Provider Administered
Cryotherapy
podophyllin resin 10%-25%15
trichloroacetic acid or
bichloroacetic acid 80%-90%
surgical removal
OR
OR
OR
OR
OR
Apply to visible warts 2x/day for 3
days, rest 4 days, 4 cycles max.
Apply once h.s., wash off after 6-10
hours 3x/week QOD, 16 weeks max.
Apply 3x/day, 16 weeks max; See
complete CDC guidelines.
Apply small amount, dry, wash off in
1-4 hours. Repeat weekly if necessary
Apply small amount, dry, apply weekly
if necessary
Intralesional interferon
Laser surgery
OR
Genital Warts (Human Papillomavirus)18
11. Gonococcal
Infections
Recommended Rx Dose/Route Alternatives
Adults, adolescents, and
children >45 kg: urogenital,
rectal
ceftriaxone
PLUS
azithromycin10
doxycycline6
OR
OR
250 mg IM in a single dose
1 g orally in a single dose
100 mg orally 2x/day for 7 days
cefixime20
400 mg orally in a single dose
azithromycin10
1 g orally in a single dose
doxycycline6
100 mg 2x/day for 7 days
test-of-cure
If the patient has severe cephalosporin
allergy:
azithromycin 2 g orally in a single dose
test-of-cure
PLUS
OR
PLUS
PLUS
Pharyngeal21 ceftriaxone
PLUS
azithromycin10
doxycycline6
OR
250 mg IM in a single dose
1 g orally in a single dose
100 mg orally 2x/day for 7 days
Pregnancy3
See complete CDC guidelines.
Adults and adolescents:
conjunctivitis
ceftriaxone 1 g IM in a single dose; irrigate infected
eye with saline solution once
Children (≤45 kg): urogenital,
rectal, pharyngeal
ceftriaxone22
125 mg IM in a single dose
Gonococcal Infections19
13. Non-Gonococcal
Urethritis (NGU)
Recommended Rx Dose/Route Alternatives
azithromycin10
doxycycline6
OR 1 g orally in a single dose
100 mg orally 2x/day for 7 days
erythromycin base7
500 mg orally
4x/day for 7 days
erythromycin ethylsuccinate8
800
mg orally 4x/day for 7 days
levofloxacin 500 mg 1x/day for 7
days
ofloxacin 300 mg 2x/day for 7 days
OR
OR
OR
Recurrent NGU3,23,24
metronidazole25
tinidazole
OR
PLUS
2 g orally in a single dose
2 g orally in a single dose
1 g orally in a single doseazithromycin (if not used for initial episode)
Nongonococcal Urethritis (NGU)
14. Pediculosis
Pubis
Recommended Rx Dose/Route Alternatives
permethrin 1% cream rinse
pyrethrins with piperonyl
butoxide
OR Apply to affected area, wash off after 10 minutes
Apply to affected area, wash off after 10 minutes
malathion 0.5% lotion, applied
8-12 hrs then washed off
ivermectin 250 µg/kg orally,
repeated in 2 weeks
OR
Pediculosis Pubis
15. Pelvic
Inflammatory
Disease
Recommended Rx Dose/Route Alternatives
1. ceftriaxone
doxycycline
With OR
metronidazole
2. cefoxitin
doxycycline
With OR
metronidazole
3. Other parenteral third-
generation cephalosporin
(e.g. ceftizoxime or cefo-
taxime)
doxycycline
With OR
metronidazole
PLUS
Without
PLUS
Without
PLUS
Without
250 mg IM in a single dose
100 mg orally 2x/day for 14 days
500 mg orally 2x/day for 14 days
2 g IM in a single dose and probenecid,
1 g, orally administered concurrently
in a single dose
100 mg orally 2x/day for 14 days
500 mg orally 2x/day for 14 days
100 mg orally 2x/day for 14 days
500 mg orally 2x/day for 14 days
Pelvic Inflammatory Disease13
Alternative oral regimens are listed in CDC’s 2010 STD Treatment Guidelines.
16. Scabies
Recommended Rx Dose/Route Alternatives
permethrin 5% cream
ivermectin
OR Apply to all areas of body from neck down, wash
off after 8-14 hours
200 µg/kg orally, repeated in 2 weeks
lindane 1%26,27
1 oz. of lotion or
30 g of cream, applied thinly
to all areas of the body from
the neck down, wash off after
8 hours
Scabies
17. Recommended Rx Dose/Route Alternatives
Primary, secondary, or early
latent 1 year
benzathine penicillin G 2.4 million units IM in a single dose doxycycline6,28
100 mg 2x/day for 14 days
tetracycline6,28
500 mg orally 4x/day for
14 days
OR
Latent 1 year, latent of
unknown duration
benzathine penicillin G 2.4 million units IM in 3 doses each at
1 week intervals (7.2 million units
total)
doxycycline6,28
100 mg 2x/day for 28 days
tetracycline6,28
500 mg orally 4x/day for
28 days
OR
Pregnancy3
See complete CDC guidelines.
Neurosyphilis aqueous crystalline penicillin G 3 to 4 million units IV every 4 hours
for 10-14 days (18-24 million units/
day)
procaine penicillin G 2.4 MU IM 1x daily
probenecid 500 mg orally 4x/day, both for
10-14 days.
PLUS
Congenital syphilis aqueous crystalline penicillin G
procaine penicillin G
OR 100,000-150,000 units/kg/day (50,000
units/kg/dose IV every 12 hours) dur-
ing the first 7 days of life and every 8
hours thereafter for a total of 10 days
50,000 units/kg/dose IM in a single dose
for 10 days
Children: Primary, secondary,
or early latent 1 year
benzathine penicillin G 50,000 units/kg IM in a single dose
(maximum 2.4 million units)
Children: Latent 1 year,
latent of unknown duration
benzathine penicillin G 50,000 units/kg IM for 3 doses at 1
week intervals (maximum total 7.2
million units)
Syphilis
Syphilis
18. Trichomoniasis
Recommended Rx Dose/Route Alternatives
metronidazole25
tinidazole29
OR 2 g orally in a single dose
2 g orally in a single dose
metronidazole25
500 mg 2x/day for 7 days
Trichomoniasis
19. 1. The recommended regimens are equally efficacious.
2. These creams are oil-based and may weaken latex condoms and diaphragms. Refer to product labeling for further information.
3. Please refer to the complete 2010 CDC Guidelines for recommended regimens.
4. Existing data do not support the use of topical agents in pregnancy.
5. Consider concurrent treatment for gonococcal infection if prevalence of gonorrhea is 5% (younger age).
6. Should not be administered during pregnancy, lactation, or to children 8 years of age.
7. If patient cannot tolerate high-dose erythromycin base schedules, change to 250 mg 4x/day for 14 days.
8. If patient cannot tolerate high-dose erythromycin ethylsuccinate schedules, change to 400 mg orally 4 times a day for 14 days.
9. Contraindicated for pregnant or lactating women.
10. Clinical experience and published studies suggest that azithromycin is safe and effective.
11. Erythromycin estolate is contraindicated during pregnancy.
12. Effectiveness of erythromycin treatment is approximately 80%; a second course of therapy may be required.
13. Patients who do not respond to oral therapy (within 72 hours) should be re-evaluated.
14 For patients with suspected sexually transmitted epididymitis, close follow-up is essential.
15. No definitive information available on prenatal exposure.
16. Treatment may be extended if healing is incomplete after 10 days of therapy.
Indicates revision from the 2006 CDC Guidelines for the Treatment of Sexually Transmitted Diseases.
Indicates update from the 2010 CDC Guidelines for the Treatment of Sexually Transmitted Diseases; see MMWR Morb Mortal Wkly Rep. 2012 Aug 10; 61(31):590-594
for details.
Notes
Notes
20. 17. Consider discontinuation of treatment after one year to assess frequency of recurrence.
18. Vaginal, cervical, urethral meatal, and anal warts may require referral to an appropriate specialist.
19. CDC recommends that treatment for uncomplicated gonococcal infections of the cervix, urethra, and/or rectum
should include dual therapy, i.e. both a cephalosporin (e.g. ceftriaxone) plus azithromycin (preferred) or doxycycline.
20. CDC recommends that cefixime in combination with azithromycin or doxycycline be used as an alternative when ceftriaxone is not available.
21. Only ceftriaxone is recommended for the treatment of pharyngeal infection. Providers should inquire about oral sexual exposure
22. Use with caution in hyperbilirubinemic infants, especially those born prematurely.
23. MSM are unlikely to benefit from the addition of nitroimidazoles.
24. Moxifloxacin 400mg orally 1x/day for 7 days effective against Mycoplasma genitalium
25. Pregnant patients can be treated with 2 g single dose.
26. Contraindicated for pregnant or lactating women, or children 2 years of age.
27. Do not use after a bath; should not be used by persons who have extensive dermatitis.
28. Pregnant patients allergic to penicillin should be treated with penicillin after desensitization.
29. Randomized controlled trials comparing single 2 g doses of metronidazole and tinidazole suggest that tinidazole is equivalent to,
or superior to, metronidazole in achieving parasitologic cure and resolution of symptoms.
Indicates revision from the 2006 CDC Guidelines for the Treatment of Sexually Transmitted Diseases.
Indicates update from the 2010 CDC Guidelines for the Treatment of Sexually Transmitted Diseases; see MMWR Morb Mortal Wkly Rep. 2012 Aug 10; 61(31):590-594
for details.
Notes (continued)
Notes
(continued)