This report identifies areas vulnerable to future climate change and food insecurity in the global tropics. It analyzes maps of climate change exposure thresholds and food security indicators to identify hotspots. Nine vulnerability domains are established based on exposure, sensitivity, and coping capacity. The most vulnerable domain has high exposure, high sensitivity, and low coping capacity. This analysis finds large areas of Africa, South Asia, and parts of Central and South America fall into this highly vulnerable category for several climate change exposures. The choice of exposure indicator influences the size and location of vulnerable populations.