The document discusses the structure and function of muscles and sarcomeres. It describes how muscles are made up of sarcomeres, which contain thick myosin filaments and thin actin filaments. Sarcomeres shorten during muscle contraction as the actin and myosin filaments slide past each other through a cross bridge cycle of formation, power stroke, detachment and reactivation of the myosin head. This causes the A band width to remain the same and the H zone and I bands to decrease in size.
three types: skeletal, cardiac, smooth
Muscle cells are called muscle fibers
Contraction depends on two kinds of Myofilaments
Actin
Myosin
Prefixes to know: myo, mys, or sarco – word relates to muscle
Each muscle is a discrete organ
Muscle Type Overview
Skeletal Muscle tissue
Skeletal
Striated
Voluntary
Cardiac Muscle tissue
Cardiac
Striated
Involuntary
Smooth Muscle tissue
Visceral
Non-striated
Involuntary
Muscle Functions
1. Producing movement
2. Maintaining posture
3. Stabilizing joints
4. Generating heat
Functional Characteristics of Muscles
Excitability (or Irritability) = ability to receive and respond to stimuli
Contractility = ability to shorten forcibly
Extensibility = ability to be stretched or extended beyond resting length
Elasticity = ability to resume resting length after stretchingMuscle (organ)
Fascicle (a portion of the muscle)
Muscle Fiber (a cell)
These levels are supracellular
Connective Tissue Layer
Epimysium
Perimysium
Endomysium
Anatomy of a Muscle
Typical ex. is a skeletal muscle
The following are all subcellular.
Myofibril = or fibril, complex organelle composed of bundles of
myofilaments
Myofilament = macromolecular structure of contractile proteins
Sarcomere = the smallest, single contracting unit of a myofibril, a segment
Gross Anatomy
Deep fascia = binds large groups of muscles into functional groups
Muscle = hundreds of fascicles bound together by epimysium
Fascicle = thousands of muscle fibers bound into discrete units by
perimysium
Muscle fiber = single muscle cell surrounded by endomysium
Generous blood and nerve supply
Microscopic Anatomy of a Muscle Fiber
Muscle Fiber = elongated, cylindrical, multinucleated muscle cell
Sarcolemma = plasma (cell) membrane of a muscle cell
Sarcoplasm = cytoplasm of muscle cell with large amounts of glycogen and
Muscles is a contractile tissue which brings about movement.
Muscle cell responsible for our movement both visible and invisible, example walking, talking, bowel movement ,urination, breathing, heartbeats, the dilation and constriction of the pupils of our eyes and many other.
When we are still sitting or standing muscle cells keep us erect.
CONT...Muscles can be regarded as motors of the body.Muscles comprises about 40% to 50% (approximate) of body weight.There are approximate 650 muscles in body.Alternating contraction and relaxation of cells
Muscle is one of the four primary tissue types of the body, and the body contains three types of muscle tissue: skeletal muscle, cardiac muscle, and smooth muscle.
three types: skeletal, cardiac, smooth
Muscle cells are called muscle fibers
Contraction depends on two kinds of Myofilaments
Actin
Myosin
Prefixes to know: myo, mys, or sarco – word relates to muscle
Each muscle is a discrete organ
Muscle Type Overview
Skeletal Muscle tissue
Skeletal
Striated
Voluntary
Cardiac Muscle tissue
Cardiac
Striated
Involuntary
Smooth Muscle tissue
Visceral
Non-striated
Involuntary
Muscle Functions
1. Producing movement
2. Maintaining posture
3. Stabilizing joints
4. Generating heat
Functional Characteristics of Muscles
Excitability (or Irritability) = ability to receive and respond to stimuli
Contractility = ability to shorten forcibly
Extensibility = ability to be stretched or extended beyond resting length
Elasticity = ability to resume resting length after stretchingMuscle (organ)
Fascicle (a portion of the muscle)
Muscle Fiber (a cell)
These levels are supracellular
Connective Tissue Layer
Epimysium
Perimysium
Endomysium
Anatomy of a Muscle
Typical ex. is a skeletal muscle
The following are all subcellular.
Myofibril = or fibril, complex organelle composed of bundles of
myofilaments
Myofilament = macromolecular structure of contractile proteins
Sarcomere = the smallest, single contracting unit of a myofibril, a segment
Gross Anatomy
Deep fascia = binds large groups of muscles into functional groups
Muscle = hundreds of fascicles bound together by epimysium
Fascicle = thousands of muscle fibers bound into discrete units by
perimysium
Muscle fiber = single muscle cell surrounded by endomysium
Generous blood and nerve supply
Microscopic Anatomy of a Muscle Fiber
Muscle Fiber = elongated, cylindrical, multinucleated muscle cell
Sarcolemma = plasma (cell) membrane of a muscle cell
Sarcoplasm = cytoplasm of muscle cell with large amounts of glycogen and
Muscles is a contractile tissue which brings about movement.
Muscle cell responsible for our movement both visible and invisible, example walking, talking, bowel movement ,urination, breathing, heartbeats, the dilation and constriction of the pupils of our eyes and many other.
When we are still sitting or standing muscle cells keep us erect.
CONT...Muscles can be regarded as motors of the body.Muscles comprises about 40% to 50% (approximate) of body weight.There are approximate 650 muscles in body.Alternating contraction and relaxation of cells
Muscle is one of the four primary tissue types of the body, and the body contains three types of muscle tissue: skeletal muscle, cardiac muscle, and smooth muscle.
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5. THE ELBOW
• Biceps – bends the arm (flexor)
• Triceps – straightens the arm (extensor)
• Humerus – anchors muscle (muscle origin)
• Radius/Ulna – acts as forearm levers (muscle insertion)
• Radius acts as a lever for the biceps
• Ulna acts as a lever for the triceps
• Cartilage – allows easy movement (smooth
surface), absorbs shock and distributes load
• Synovial fluid – provides food, oxygen, and lubrication to
the cartilage
• Joint capsule – seals the joint space and provides passive
stability by limiting range of movement
7. KNEE JOINT VS HIP JOINT
Similarities:
-
Both are synovial joints
-
Both are involved in the movement of the leg
Differences:
8. MUSCLE STRUCTURE
sarcomeres < myofibrils < muscle fibers = MUSCLES
muscle fibers – long multinucleate cells
Within each muscle fiber are cylindrical structures called
myofibrils
Myofibrils consist of repeating units called
sarcomeres, which have light and dark bands
10. STRIATED MUSCLE FIBER
Sarcolemma – specialized plasma
membrane
Sarcoplasmic reticulum – specialized
endoplasmic reticulum designed for muscle
contraction (contains high Ca2+)
Myofibrils – tubular fibers divided into
sections called sarcomeres, and made up of
two different myofilaments (actin & myosin)
Mitochondria – large numbers in order to
produce enough ATP for muscle contraction
14. SARCOMERES
H zone – area only occupied by the thick
filaments (myosin)
I bands (light) – regions occupied by
only thin filaments (actin)
A bands (dark) - are the region occupied
by both filaments (overlap)
Z lines – represent the extremeties of a
single sarcomere
15. SARCOMERES
H zone – area only occupied by the thick
filaments (myosin)
I bands (light) – regions occupied by
only thin filaments (actin)
A bands (dark) - are the region occupied
by both filaments (overlap)
Z lines – represent the extremeties of a
single sarcomere
23. SARCOMERE
CONTRACTION
Four Stages of Cross Bridge Cycle
1) Cross Bridge Formation
2) Power Stroke
3) Cross Bridge Detachment
4) Reactivation of Myosin Head