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Cardiogenic shock PPV
1. The Use Of PEEP With Cardiogenic
Shock Patients
Aziza Saleh Alamri
2. Objectives
• Introduction of Cardiogenic shock
• Cardiovascular effects of PEEP
• Management (VIP)
• Mechanical ventilation
Use of PEEP
3. What is Cardiogenic shock?
Is a clinical condition of inadequate tissue
perfusion due to cardiac dysfunction.
• Myocardial infarction
• End-stage cardiomyopathy
• Arrhythmias
• Low cardiac output
9. 2. A patient came to ER having
• The feel of intense chest pain and tightness
• Slightly increased and unlabored RR
• Oxygen saturation: 93% (on room air).
• Conscious and alert
• Restless and anxious
• Suspected MI
10. 1. Non-rebreather face mask (15 L/min)
2. NPPV
3. Intubation
؟What is the appropriate action
11. 1. Chest pain
2. Sweating
3. Fatigue
4. Dyspnea
5. Edema
6. On CxR : it revealed butterfly pulmonary
opacities
3. A patient came to ER having
12. ؟What is the appropriate action
The use of NIV for patients with ACPE is highly
supported .
Continuous positive airway pressure reduces mortality
more in patients with ACPE secondary to acute
myocardial ischemia or infarction.
13. Importance of Ventilation
• To protect the airway and maintain oxygen supply in
patients with a deterioration in consciousness or cardiac
arrest.
• To treat acute respiratory failure, most often due to
cardiogenic pulmonary edema.
• To raise the arterial pH in metabolic acidosis
14. Infusion “Fluid Resuscitation in Shock”
• Initial fluid resuscitation
• Risk of edema (CHF)
• Is my patient's shock fluid responsive?
• Determining Fluid Responsiveness in Shock
Type of fluid “Crystalloid”
How fast to infuse it “300-500mL over 20-30 minutes”
Define a positive test: ↑arterial pressure, ↓HR, ↑ urine output
Set a safety limit :↑ in CVP by 4 cm H2O “To avoid pulmonary
edema”
15. Pump “Use of vasoactive Drugs in Shock”
• Inotropes
Adrenaline, Dobutamine
• Vasopressors
Noradrenaline, Vasopressin
• Dopamine
• Aspirin and Heparin
• Diuretics
16. Use Of PEEP
Don’t have an effectDo have an effect
↓ LV oxygen demand and
improved oxygen delivery to the
ischaemic myocardium
↓Venous return, LV filling,
CO and overall organ
perfusion
↓ Intracardiac lactate
production
↑ RV afterload
17. • Improve hemodynamics, respiratory function
and oxygenation in patients with acute systolic
heart failure and pulmonary oedema compared
with oxygen therapy alone.
• lower rates of intubation
18. • A number of reports in patients with
cardiogenic shock suggest that the
hemodynamic effects of PEEP may work
in favor of the patient with severe left
heart failure
is the irreversible necrosis of heart muscle secondary to prolonged ischemia
chronic disease of the heartmuscle (myocardium), in which the muscle isabnormally enlarged, thickened, and/or stiffened+loses the ability to pumping + arrhythmias
External pressure on the IVC (decreased venous return )+(increased right ventricular dilatation)+(decreased left ventricular filling and cardiac output)
myocardial infarction (MI) with arterial oxygen desaturation
1. MI during the first six hours after presentation
2. If respiratory distress, respiratory acidosis, and/or hypoxia persist
3. If pt. deteriorates + decrease LOC or uncooperative
all patients in shock deserve some initial fluid resuscitation, even if volume overloaded (e.g., end stage CHF), but "too much fluid carries the risk of edema with its unwanted consequences," and the amount of fluid should be "closely monitored.
2013
1. PEEP exerted unfavourable haemodynamic effects such as less venous blood return,
increasing (RV) afterload, decreasing (LV) filling and depressing CO and overall organ perfusion
2. other studies did not indicate that PPV had detrimental effects on LV function
and showed that, conversely, PEEP decreased LV oxygen demand and improved oxygen delivery to the
ischaemic myocardium, as evidenced by a decreased intracardiac lactate production.
PCWP “normal vs. abnormal “ 12 out of 13 patients with a PCWP ≥19 improved CO with peep of 3-8
As with any intervention, PEEP has a broad spectrum of haemodynamic consequences,
which can be alternatively favourable or unfavourable depending on the clinical scenario in
which it is used.
severe left systolic heart failure, acute MI and cardiogenic shock will always require clinical judgement, we conclude that most patients will benefit from its use
RV infarcts or have hypovolaemia, care must be exercised to ensure that cardiac under-filling does not occur with the decreased venous return which accompanies PEEP