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INTRA AORTIC
BALLOON PUMP
Dr. Soham J Shah KEM,
Hospital Mumbai
Points for discussion :
1. History
2. Principles of IABP function
3. Physiology and Pathophysiology of IABP
4. Indications and Contraindications
5. Anatomy of device
6. Techniques of insertion, complications
and removal
7. References
8. Video presentation.
 ADRIAN
KANTROVITZ
 Started experiments
on DIASTOLIC
AUGMENTATION at
Western Reserve
University as a
research fellow
(1952) in the
Department of
Cardiovascular
Physiology under
Dr.Carl Wiggers.
 In 1958, Harken :
 “Removal of some of
the blood volume via
the femoral artery
during systole and
replacing it rapidly in
diastole, so called
diastolic augmentation
as a treatment for left
ventricular failure.
S.MOULOPOULOS
& team (1962)
At Cleveland clinic , conducted
preliminary studies with latex
tubing tied around the end of
polyethylene catheter with
multiple side holes.
The tubing,catheter and balloon
formed a closed system that was
filled with CO2.
Stroke was triggered with the aid
of ECG.
 Moulopoulos and colleagues developed a
prototype in which IABP inflation and deflation
were timed to the cardiac cycle.
In 1967 Adrian Kantrowitz after gaining enough experience in
animal experiments, He identified that the use of helium as the
shuttle gas gave sufficient transit speed to assure appropriate
timing.
“ On June 29, 1967, 45-year-old woman who was comatose,
anuric, cold, and cyanotic , her blood pressure was
unobtainable. The patient was clearly near death.“
They inserted the balloon pump and she was pumped for about
7 hours, her condition stabilized, and the pump was removed.
The patient recovered and was subsequently discharged from
the hospital.
Contibutors
BUKLEY et al- Balloon inflation in diastole
augments coronary perfusion and deflation just
before systole markedly reduces resistance to the
left ventricular ejection and thereby reduces cardiac
work and myocardial o2 consumption.
In 1973 two different groups headed by
Buckley.M.J & Housman LB, reported the
successful utilization of IABP in patients who
were unable to be weaned from
cardiopulmonary bypass.
MUNDTH & coworkers:Reported a patient who sustained
cardiogenic shock following myocardial infarction and was
stabilised with IABP and subsequently underwent coronary
revascularisation with the support of the balloon pump and
had an uneventful recovery. This was the first report where
the application of the IABP extended successfully to
support heart failure post coronary artery surgery.
Percutaneous insertion (1980)
 Bregman D, Casarella WJ.
First Percutaneous insertion of intra-aortic balloon pump:
Initial clinical experience. Ann Thorac Surg
 Subramanian VA et al.
Preliminary clinical experience with percutaneous intra-aortic
balloon pumping.
The first prefolded IAB was developed in 1986.
2
IABP
Temporary support for the left ventricle by mechanically
displacing blood within the aorta
Most common and widely available methods of mechanical
circulatory support
Concepts:
- Systolic unloading
- Diastolic augmentation
Traditionally used in surgical and non surgical patients
with cardiogenic shock
Physiologicaleffects of IABPtherapy
• The primary goal of IABP treatment is to improve the
ventricular performance of the failing heart by
facilitating an increase in myocardial oxygen supply
and a decrease in myocardial oxygen demand.
• IABP inflates at the onset of diastole, thereby
increasing diastolic pressure and deflates just before
systole, thus reducing LV afterload. Increases coronary
perfusion
 Primary effect of IABP
1) Increase myocardial oxygen supply
2) Decrease myocardial oxygen demand
 Secondary effect of IABP
1) Increase in cardiac output
2) Increasing in MAP that will lead to
improvement of perfusion to all organ
3) Increases LV ejection
 Effects on other systems
 Renal = increases renal perfusion and urine
output
 Neurological= increasing cerebral perfusion
and enhancing neurological state
 Vascular- increases peripheral perfusion
Basicprinciples of counterpulsation
• Counterpulsation (augmentation) is a term that
describes balloon inflation in diastole and deflation
in early systole.
• Balloon inflation causes ‘volume displacement’ of blood
within the aorta, both proximally and distally. This
leads to a potential increase in coronary blood flow
and potential improvements in systemic perfusion by
augmentation of the intrinsic ‘Windkessel effect
3
Indications for IABP
1. Cardiogenic shock:
- Associated with acute MI
VSR, Ischaemic MR
2. In association with CABG :
Preoperative insertion
- Patients with severe LV dysfunction
- Patients with intractable ischemic arrhythmias
Postoperative insertion
- Postcardiotomy cardiogenic shock
3. In association with nonsurgical revascularization:
-Hemodynamically unstable infarct patients
-High risk coronary interventions
- severe LV dysfunction, LMCA, complex coronary artery disease
4. Stabilization of cardiac transplant recipient before insertion of VAD
Post infarction angina
Ventricular arrhythmias relathed to ischemia
4
CONTRAINDICATIONS
Absolute-
▫ Significant aortic regurgitation
▫ Aortic dissection
▫ Aortic stents
Relative -
▫ Severe atherosclerosis
Abdominal aortic aneurysm
▫ Uncontrolled septicemia
▫ Uncontrolled bleeding diathesis
▫ Severe bilateral peripheral vascular disease
Working principles of IABP
• Balloon pump device
• Insertion of IABP
• Position of balloon
• Effects of IABP
• Management of IABP
• Troubleshooting
• Weaning & Removal
11
The Device
THE DEVICE
 Monitor system
17
Introducer needle
• Guide wire
• Vessel dilators
• Sheath
• IABP (34 or 40cc)
• Gas tubing
• 60-mL syringe
• Three-way stopcock
IABP Kit Contents
IABP catheter:
10-20 cm long polyurethane bladder
25cc to 50cc capacity
Optimal 85% of aorta occluded (not 100%)
The shaft of the balloon catheter contains 2 lumens:
- one allows for gas exchange from console
to balloon
- second lumen
- for catheter delivery over a guide wire
- for monitoring of central aortic
pressure after installation.
Intra Aortic Balloon Catheter
Tip
15
Balloon sizing
Sizing based on patients
height
Four common balloon
sizes
Balloon length and
diameter increases with
each larger size
40 cm³ balloon is most
commonly used
Paediatric balloons also
available : sizes 2.5, 5.0,
12.0 and 20 cm³
Balloon size Height
50 cm³ > 6 feet
40 cm³ 5 feet 4 inch
to 6 feet
34 cm³ 5 feet to 5
feet 4 inch
25 cm³ < 5 feet
Insertion
 1) Percutaneous insertion
via trans Femoral, Axillary, Brachial and Radial
approach
 2) Femoral artery cutdown insertion
 3) Intraoperatively insertion through Ascending
aorta (Transthoracic insertion)
Insertion
Majority by femoral artery
by Seldinger technique
Alternatively
•Ascending aorta
•Axillary artery
•Brachial artery
•Radial artery
18
Connect ECG
Set up pressure lines
Femoral access – followed by insertion of the supplied
sheath
IABP insertion
19
Take the entire catheter and T handle as one unit
(DO NOT disconnect one-way
valve when removing the
extracorporeal tubing from the
tray.)
Pull out the T- handle only as shown
22
Connecting to console:
- The central lumen of the catheter is flushed and connected to pressure
tubing with 3 way and then to a pressure transducer to allow for
monitoring of central aortic pressure.
- Zero the transducer
Initial set-up:
- Once connected properly the console would show ECG and pressure
waveforms.
- Check mean pressure
- Make sure the setting is at “auto”
- Usually IABP started at 1:1 or 1:2 augmentation
- Usually Augmentation is kept at maxim
24
POSITION OF IABP
The tip should be
situated distal to left
subclavian artery
take off.
On chest radiography
optimal position will be
level of the carina or
b/w the 2nd and 3rd
intercostal spaces.
Too far— subclavian &
vertebral occlusion
Too low— mesenteric
& renal ischemia
1) ECG signal – most
common
• Inflation
- middle of T wave
• Deflation
– peak of R wave
1) ECG
2) Pressure wave
3) Internal
4) Pacer V/AV
5) Pacer A
Modes of operation
The normal IABP blood pressure
waveform
TIMING
The “normal” augmented waveform
Increased coronary
perfusion
How to check waveform is acceptable ?
First change from 1:1 to 1:2 augmentation
How to check waveform is acceptable ?
Check the dicrotic notch
See if augmentation starts at that point
This should produce a sharp “V” at inflation.
and diastolic augmented wave > Systolic
wave.
Timing Errors
“Balloon too
large”
syndrome
Variation in balloon pressure wave forms
Increased duration of
plateau due to longer
diastolic phase
Decreased duration
of plateau due to
shortened diastolic
phase
IMP management during IABP
Never leave in standby by mode for more than 20 minutes >
thrombus formation
Patient Management During IABP
support
Complications
• Limb ischemia
• Bleeding at insertion site
• Infection
• Aortic dissection – tearing aorta during ballon
insertion
• Thromboembolism
• Reducing urine output
• Balloon catheter rupture and gas loss
• Hemolysis
• Thrombocytopenia
Weaning of IABP
Timing of weaning:
- Patient should be stable for 12 – 24 hours
- Decrease inotropic support
- Decrease pump ratio
– From 1:1 to 1:2 or 1:3
- Decrease augmentation
- Monitor patient closely
-ABG,Urine output, blood
pressure should be good
– If patient becomes unstable, weaning should be
immediately discontinued
Weaning
Controversies
 There has been different schools of thought
regarding weaning methods
 Volume vrs Ratio .. Which is better ?
 Ratio – reduction in augmention from 1:1 to
1:2 for 4 hours then 1:3 for one hour then
removal
 Volume – 10% of volume reduction every hour
for 5 hours then removal.
 Few papers have published regarding weaning
which is better includes
1. Onarati et al (2013) Italy sample size -30
2. Tokita et.all (2014) USA, sample size- 30
3. Hsin et al. (2013) Taiwan sample size -85
4. Bigmani et al. (2012) Italy
5. Lewis et al. (2006) Australia – says Volume
weaning is better
6. Manohar et al (2012) USA sample size 429
 The inference from all above mentioned
papers is There has been no clear evidence
regarding which method is superior in weaning
from IABP still inconclusive.
 Impella Vrs IABP
 1) Impella vrs IABP in acute MI . Brunilda
Alushi et.all Germany
 2) Impella vrs IABP in acute MI. Abdelmoniem
Moustafa et.all USA
 Impella is asssociated with higher incidence of
bleeding, limb compliocations, hemolysis.
Video Presentation
References
 Cardiopulmonary bypass priciples and techniques- Amman Jordan
 Manual of perioperative care in cardiac surgery- Robert M.Bojar
 Oxford handbook of cardiac surgery
 Sabiston Spencer book of cardiac surgery
 IABP: history-evolution pathophysiology indications:what we need
to know H. Parissis, V. Graham*et al.
 A prospective randomized study comparing surgical and
percutaneous removal of intraaortic balloon pump Michael J. Rohrer
et al.
 Percutaneous Intraaortic Balloon pumping: Initial Clinical
Experience.. David Bregman, M.D., and William J. Casarella, M.D.
 Intra-aortic balloon pump postcardiac surgery: A literature review
Mansour Jannati et al.
 Intra-aortic balloon pump in CABG – Factors affecting outcome Okonta KE,
*Kanagarajan N, Anbarasu M.
Thank you.

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IABP- intra Aortic Balloon Pump

  • 1. INTRA AORTIC BALLOON PUMP Dr. Soham J Shah KEM, Hospital Mumbai
  • 2. Points for discussion : 1. History 2. Principles of IABP function 3. Physiology and Pathophysiology of IABP 4. Indications and Contraindications 5. Anatomy of device 6. Techniques of insertion, complications and removal 7. References 8. Video presentation.
  • 3.  ADRIAN KANTROVITZ  Started experiments on DIASTOLIC AUGMENTATION at Western Reserve University as a research fellow (1952) in the Department of Cardiovascular Physiology under Dr.Carl Wiggers.
  • 4.  In 1958, Harken :  “Removal of some of the blood volume via the femoral artery during systole and replacing it rapidly in diastole, so called diastolic augmentation as a treatment for left ventricular failure.
  • 5. S.MOULOPOULOS & team (1962) At Cleveland clinic , conducted preliminary studies with latex tubing tied around the end of polyethylene catheter with multiple side holes. The tubing,catheter and balloon formed a closed system that was filled with CO2. Stroke was triggered with the aid of ECG.
  • 6.  Moulopoulos and colleagues developed a prototype in which IABP inflation and deflation were timed to the cardiac cycle.
  • 7. In 1967 Adrian Kantrowitz after gaining enough experience in animal experiments, He identified that the use of helium as the shuttle gas gave sufficient transit speed to assure appropriate timing. “ On June 29, 1967, 45-year-old woman who was comatose, anuric, cold, and cyanotic , her blood pressure was unobtainable. The patient was clearly near death.“ They inserted the balloon pump and she was pumped for about 7 hours, her condition stabilized, and the pump was removed. The patient recovered and was subsequently discharged from the hospital.
  • 8. Contibutors BUKLEY et al- Balloon inflation in diastole augments coronary perfusion and deflation just before systole markedly reduces resistance to the left ventricular ejection and thereby reduces cardiac work and myocardial o2 consumption. In 1973 two different groups headed by Buckley.M.J & Housman LB, reported the successful utilization of IABP in patients who were unable to be weaned from cardiopulmonary bypass.
  • 9. MUNDTH & coworkers:Reported a patient who sustained cardiogenic shock following myocardial infarction and was stabilised with IABP and subsequently underwent coronary revascularisation with the support of the balloon pump and had an uneventful recovery. This was the first report where the application of the IABP extended successfully to support heart failure post coronary artery surgery.
  • 10. Percutaneous insertion (1980)  Bregman D, Casarella WJ. First Percutaneous insertion of intra-aortic balloon pump: Initial clinical experience. Ann Thorac Surg  Subramanian VA et al. Preliminary clinical experience with percutaneous intra-aortic balloon pumping. The first prefolded IAB was developed in 1986.
  • 11. 2 IABP Temporary support for the left ventricle by mechanically displacing blood within the aorta Most common and widely available methods of mechanical circulatory support Concepts: - Systolic unloading - Diastolic augmentation Traditionally used in surgical and non surgical patients with cardiogenic shock
  • 12. Physiologicaleffects of IABPtherapy • The primary goal of IABP treatment is to improve the ventricular performance of the failing heart by facilitating an increase in myocardial oxygen supply and a decrease in myocardial oxygen demand.
  • 13. • IABP inflates at the onset of diastole, thereby increasing diastolic pressure and deflates just before systole, thus reducing LV afterload. Increases coronary perfusion
  • 14.  Primary effect of IABP 1) Increase myocardial oxygen supply 2) Decrease myocardial oxygen demand  Secondary effect of IABP 1) Increase in cardiac output 2) Increasing in MAP that will lead to improvement of perfusion to all organ 3) Increases LV ejection
  • 15.  Effects on other systems  Renal = increases renal perfusion and urine output  Neurological= increasing cerebral perfusion and enhancing neurological state  Vascular- increases peripheral perfusion
  • 16. Basicprinciples of counterpulsation • Counterpulsation (augmentation) is a term that describes balloon inflation in diastole and deflation in early systole. • Balloon inflation causes ‘volume displacement’ of blood within the aorta, both proximally and distally. This leads to a potential increase in coronary blood flow and potential improvements in systemic perfusion by augmentation of the intrinsic ‘Windkessel effect
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  • 19. 3 Indications for IABP 1. Cardiogenic shock: - Associated with acute MI VSR, Ischaemic MR 2. In association with CABG : Preoperative insertion - Patients with severe LV dysfunction - Patients with intractable ischemic arrhythmias Postoperative insertion - Postcardiotomy cardiogenic shock 3. In association with nonsurgical revascularization: -Hemodynamically unstable infarct patients -High risk coronary interventions - severe LV dysfunction, LMCA, complex coronary artery disease 4. Stabilization of cardiac transplant recipient before insertion of VAD Post infarction angina Ventricular arrhythmias relathed to ischemia
  • 20. 4
  • 21. CONTRAINDICATIONS Absolute- ▫ Significant aortic regurgitation ▫ Aortic dissection ▫ Aortic stents Relative - ▫ Severe atherosclerosis Abdominal aortic aneurysm ▫ Uncontrolled septicemia ▫ Uncontrolled bleeding diathesis ▫ Severe bilateral peripheral vascular disease
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  • 23. Working principles of IABP • Balloon pump device • Insertion of IABP • Position of balloon • Effects of IABP • Management of IABP • Troubleshooting • Weaning & Removal
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  • 29. 17 Introducer needle • Guide wire • Vessel dilators • Sheath • IABP (34 or 40cc) • Gas tubing • 60-mL syringe • Three-way stopcock IABP Kit Contents
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  • 34. IABP catheter: 10-20 cm long polyurethane bladder 25cc to 50cc capacity Optimal 85% of aorta occluded (not 100%) The shaft of the balloon catheter contains 2 lumens: - one allows for gas exchange from console to balloon - second lumen - for catheter delivery over a guide wire - for monitoring of central aortic pressure after installation.
  • 36. Tip
  • 37. 15 Balloon sizing Sizing based on patients height Four common balloon sizes Balloon length and diameter increases with each larger size 40 cm³ balloon is most commonly used Paediatric balloons also available : sizes 2.5, 5.0, 12.0 and 20 cm³ Balloon size Height 50 cm³ > 6 feet 40 cm³ 5 feet 4 inch to 6 feet 34 cm³ 5 feet to 5 feet 4 inch 25 cm³ < 5 feet
  • 38.
  • 39. Insertion  1) Percutaneous insertion via trans Femoral, Axillary, Brachial and Radial approach  2) Femoral artery cutdown insertion  3) Intraoperatively insertion through Ascending aorta (Transthoracic insertion)
  • 40. Insertion Majority by femoral artery by Seldinger technique Alternatively •Ascending aorta •Axillary artery •Brachial artery •Radial artery
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  • 42.
  • 43. 18 Connect ECG Set up pressure lines Femoral access – followed by insertion of the supplied sheath IABP insertion
  • 44. 19 Take the entire catheter and T handle as one unit (DO NOT disconnect one-way valve when removing the extracorporeal tubing from the tray.) Pull out the T- handle only as shown
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  • 47. 22 Connecting to console: - The central lumen of the catheter is flushed and connected to pressure tubing with 3 way and then to a pressure transducer to allow for monitoring of central aortic pressure. - Zero the transducer Initial set-up: - Once connected properly the console would show ECG and pressure waveforms. - Check mean pressure - Make sure the setting is at “auto” - Usually IABP started at 1:1 or 1:2 augmentation - Usually Augmentation is kept at maxim
  • 48. 24
  • 49. POSITION OF IABP The tip should be situated distal to left subclavian artery take off. On chest radiography optimal position will be level of the carina or b/w the 2nd and 3rd intercostal spaces. Too far— subclavian & vertebral occlusion Too low— mesenteric & renal ischemia
  • 50.
  • 51. 1) ECG signal – most common • Inflation - middle of T wave • Deflation – peak of R wave
  • 52. 1) ECG 2) Pressure wave 3) Internal 4) Pacer V/AV 5) Pacer A
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  • 56.
  • 57. The normal IABP blood pressure waveform
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  • 62. The “normal” augmented waveform Increased coronary perfusion
  • 63. How to check waveform is acceptable ? First change from 1:1 to 1:2 augmentation
  • 64. How to check waveform is acceptable ? Check the dicrotic notch See if augmentation starts at that point This should produce a sharp “V” at inflation. and diastolic augmented wave > Systolic wave.
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  • 76. Variation in balloon pressure wave forms Increased duration of plateau due to longer diastolic phase Decreased duration of plateau due to shortened diastolic phase
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  • 79. Never leave in standby by mode for more than 20 minutes > thrombus formation Patient Management During IABP support
  • 80. Complications • Limb ischemia • Bleeding at insertion site • Infection • Aortic dissection – tearing aorta during ballon insertion • Thromboembolism
  • 81. • Reducing urine output • Balloon catheter rupture and gas loss • Hemolysis • Thrombocytopenia
  • 82.
  • 83. Weaning of IABP Timing of weaning: - Patient should be stable for 12 – 24 hours - Decrease inotropic support - Decrease pump ratio – From 1:1 to 1:2 or 1:3 - Decrease augmentation - Monitor patient closely -ABG,Urine output, blood pressure should be good – If patient becomes unstable, weaning should be immediately discontinued
  • 85. Controversies  There has been different schools of thought regarding weaning methods  Volume vrs Ratio .. Which is better ?  Ratio – reduction in augmention from 1:1 to 1:2 for 4 hours then 1:3 for one hour then removal  Volume – 10% of volume reduction every hour for 5 hours then removal.
  • 86.  Few papers have published regarding weaning which is better includes 1. Onarati et al (2013) Italy sample size -30 2. Tokita et.all (2014) USA, sample size- 30 3. Hsin et al. (2013) Taiwan sample size -85 4. Bigmani et al. (2012) Italy 5. Lewis et al. (2006) Australia – says Volume weaning is better 6. Manohar et al (2012) USA sample size 429
  • 87.  The inference from all above mentioned papers is There has been no clear evidence regarding which method is superior in weaning from IABP still inconclusive.
  • 88.
  • 89.  Impella Vrs IABP  1) Impella vrs IABP in acute MI . Brunilda Alushi et.all Germany  2) Impella vrs IABP in acute MI. Abdelmoniem Moustafa et.all USA  Impella is asssociated with higher incidence of bleeding, limb compliocations, hemolysis.
  • 91. References  Cardiopulmonary bypass priciples and techniques- Amman Jordan  Manual of perioperative care in cardiac surgery- Robert M.Bojar  Oxford handbook of cardiac surgery  Sabiston Spencer book of cardiac surgery  IABP: history-evolution pathophysiology indications:what we need to know H. Parissis, V. Graham*et al.  A prospective randomized study comparing surgical and percutaneous removal of intraaortic balloon pump Michael J. Rohrer et al.  Percutaneous Intraaortic Balloon pumping: Initial Clinical Experience.. David Bregman, M.D., and William J. Casarella, M.D.  Intra-aortic balloon pump postcardiac surgery: A literature review Mansour Jannati et al.  Intra-aortic balloon pump in CABG – Factors affecting outcome Okonta KE, *Kanagarajan N, Anbarasu M.