The document discusses the top 5 cancers affecting men in South Africa: prostate cancer, colorectal cancer, lung cancer, Kaposi sarcoma, and bladder cancer. It provides information on symptoms, risk factors, screening recommendations, and treatment options for each cancer. CANSA (Cancer Association of South Africa) urges men not to delay cancer screening, as early detection is important, and describes its initiatives to raise awareness and provide screening programs for men's health issues and cancers.
CANSA raises awareness of prostate cancer, the most common male cancer globally and locally and showing significant increases.* According to the National Cancer Registry, South African men have a 1:19 risk for being diagnosed in their lifetime. International and local research indicates that the risk for aggressive prostate cancer is higher in black men.
https://www.cansa.org.za/protect-your-manhood/
This November, the Cancer Association of South Africa (CANSA) calls on men to be responsible for their health and to take advantage of cancer screening available at CANSA Care Centres. The five leading cancers affecting men * according to the 2016 National Cancer Registry (NCR) are prostate, colorectal, lung, non-Hodgkin’s lymphoma and bladder cancer. #CANSAscreening #MensHealth
https://cansa.org.za/mens-health/
CANSA places the focus on the ‘Big 5’ cancers affecting SA men during its Men’s Health Awareness Campaign in November, namely, prostate, colorectal, Kaposi sarcoma (a type of skin cancer), lung and bladder cancer. However, it’s vital that men be pro-active, stepping up and taking responsibility for their health all year round.
Read more: http://www.cansa.org.za/mens-health/
The Cancer Association of South Africa (CANSA) launches its Colorectal Cancer Awareness Campaign in partnership with Medtronic.
Colorectal cancer is the second most common cancer in men (following prostate cancer) and the third most common cancer in women (following breast and cervical cancer). An estimated 6 927 new cases of colorectal cancer were diagnosed in South Africa in 2018 which was about 6.5% of all cancers (1). More men (7.3% of all cancers) than women (5.7% of all cancers) were diagnosed with colorectal cancer in this same year.
The aim of the Medtronic and CANSA partnership aim is to provide Colorectal Cancer Awareness and education so patients can get treated at early stages and offered patient support through CANSA's patient care and support programmes.
https://www.cansa.org.za/adopt-a-balanced-lifestyle/
In October CANSA focuses on breast cancer, particularly turning the spotlight on the needs of patients with advanced or metastatic breast cancer (MBC). Breast cancer is the leading cancer affecting women in South Africa. According to the National Cancer Registry, 1 in 26 women are at risk of being diagnosed in their lifetime. Read more:
https://www.cansa.org.za/highlighting-the-needs-of-advanced-breast-cancer-patients/
Men's Health & Primary Care: Improving Access and OutcomesMen's Health Forum
Presentation made to the EMHF Primary Care Roundtable about men's health and primary care access - including usage of the internet for health purposes - England - July 2, 2014
CANSA raises awareness of prostate cancer, the most common male cancer globally and locally and showing significant increases.* According to the National Cancer Registry, South African men have a 1:19 risk for being diagnosed in their lifetime. International and local research indicates that the risk for aggressive prostate cancer is higher in black men.
https://www.cansa.org.za/protect-your-manhood/
This November, the Cancer Association of South Africa (CANSA) calls on men to be responsible for their health and to take advantage of cancer screening available at CANSA Care Centres. The five leading cancers affecting men * according to the 2016 National Cancer Registry (NCR) are prostate, colorectal, lung, non-Hodgkin’s lymphoma and bladder cancer. #CANSAscreening #MensHealth
https://cansa.org.za/mens-health/
CANSA places the focus on the ‘Big 5’ cancers affecting SA men during its Men’s Health Awareness Campaign in November, namely, prostate, colorectal, Kaposi sarcoma (a type of skin cancer), lung and bladder cancer. However, it’s vital that men be pro-active, stepping up and taking responsibility for their health all year round.
Read more: http://www.cansa.org.za/mens-health/
The Cancer Association of South Africa (CANSA) launches its Colorectal Cancer Awareness Campaign in partnership with Medtronic.
Colorectal cancer is the second most common cancer in men (following prostate cancer) and the third most common cancer in women (following breast and cervical cancer). An estimated 6 927 new cases of colorectal cancer were diagnosed in South Africa in 2018 which was about 6.5% of all cancers (1). More men (7.3% of all cancers) than women (5.7% of all cancers) were diagnosed with colorectal cancer in this same year.
The aim of the Medtronic and CANSA partnership aim is to provide Colorectal Cancer Awareness and education so patients can get treated at early stages and offered patient support through CANSA's patient care and support programmes.
https://www.cansa.org.za/adopt-a-balanced-lifestyle/
In October CANSA focuses on breast cancer, particularly turning the spotlight on the needs of patients with advanced or metastatic breast cancer (MBC). Breast cancer is the leading cancer affecting women in South Africa. According to the National Cancer Registry, 1 in 26 women are at risk of being diagnosed in their lifetime. Read more:
https://www.cansa.org.za/highlighting-the-needs-of-advanced-breast-cancer-patients/
Men's Health & Primary Care: Improving Access and OutcomesMen's Health Forum
Presentation made to the EMHF Primary Care Roundtable about men's health and primary care access - including usage of the internet for health purposes - England - July 2, 2014
Author and lecturer Nelson Vergel speaks about erectile dysfunction, testosterone replacement, nutrition, supplementation and exercise techniques for best health and performance. You can find this information in www.ExcelMale.com and www.TestosteroneWisdom.com
Think Before You Eat and Drink
The Cancer Association of South Africa (CANSA) continues its 365 Health Challenge and encourages everyone to eat and drink smartly. Research strongly indicates that making smart choices regarding what is taken in and exercising regularly can have a positive effect, not only on a person’s well-being, but also reduces individual cancer risk.
https://www.cansa.org.za/adopt-a-balanced-lifestyle/
An informative and, dare I say, entertaining view of prostate cancerTamara Paton
I put this presentation together for my husband, a family doctor who presents to small community groups.
This marks my first attempt at following the Slide:ology approach.
During June, the Cancer Association of South Africa (CANSA) reinforces the message of its 365 Day Health Campaign, that individuals have the power to lower cancer risk by making healthy lifestyle choices. Most people are not aware that drinking any type of alcohol (even in small amounts) increases the cancer risk. CANSA highlights the toll that alcohol takes on bodies and how it affects those around them.
www.cansa.org.za
Take A Deep Breath, for Health’s Sake!
Afrikaanse Media Vrystelling
View Infographics
26 April 2019 – Tobacco smoking is the main cause for unhealthy lungs, lung cancer, and over 20 other types of cancer. CANSA urges the public to consider quitting the use of tobacco in any form, to help lower cancer risk, as part of its 365 Day Health Challenge, and leading up to #WorldNoTobaccoDay (31 May).
Read more: https://www.cansa.org.za/take-a-deep-breath-for-healths-sake/
Surviving and Thriving with Gynecologic Cancer - 9.7.19Summit Health
Join Gynecologic Oncology and wellness experts for a special "brunch and learn," event for ovarian, cervical and other gynecologic cancer survivors and champions. Speaker-led sessions will cover innovation in treatment and complementary medicine to help manage menopause and other symptoms. Moderated by Darlene Gibbon, MD. FACOG, Medical Director of Gynecologic Oncology.
Other event materials can be found under the Patient Tools tab on this page: https://www.summitmedicalgroup.com/service/gynecological-oncology/
Cancer Awareness By Ms. Susmita Mitra
This is part of the HELP Talk series at HELP,Health Education Library for People, the worlds largest free patient education library www.healthlibrary.com.
For info log on to www.healthlibrary.com.
Author and lecturer Nelson Vergel speaks about erectile dysfunction, testosterone replacement, nutrition, supplementation and exercise techniques for best health and performance. You can find this information in www.ExcelMale.com and www.TestosteroneWisdom.com
Think Before You Eat and Drink
The Cancer Association of South Africa (CANSA) continues its 365 Health Challenge and encourages everyone to eat and drink smartly. Research strongly indicates that making smart choices regarding what is taken in and exercising regularly can have a positive effect, not only on a person’s well-being, but also reduces individual cancer risk.
https://www.cansa.org.za/adopt-a-balanced-lifestyle/
An informative and, dare I say, entertaining view of prostate cancerTamara Paton
I put this presentation together for my husband, a family doctor who presents to small community groups.
This marks my first attempt at following the Slide:ology approach.
During June, the Cancer Association of South Africa (CANSA) reinforces the message of its 365 Day Health Campaign, that individuals have the power to lower cancer risk by making healthy lifestyle choices. Most people are not aware that drinking any type of alcohol (even in small amounts) increases the cancer risk. CANSA highlights the toll that alcohol takes on bodies and how it affects those around them.
www.cansa.org.za
Take A Deep Breath, for Health’s Sake!
Afrikaanse Media Vrystelling
View Infographics
26 April 2019 – Tobacco smoking is the main cause for unhealthy lungs, lung cancer, and over 20 other types of cancer. CANSA urges the public to consider quitting the use of tobacco in any form, to help lower cancer risk, as part of its 365 Day Health Challenge, and leading up to #WorldNoTobaccoDay (31 May).
Read more: https://www.cansa.org.za/take-a-deep-breath-for-healths-sake/
Surviving and Thriving with Gynecologic Cancer - 9.7.19Summit Health
Join Gynecologic Oncology and wellness experts for a special "brunch and learn," event for ovarian, cervical and other gynecologic cancer survivors and champions. Speaker-led sessions will cover innovation in treatment and complementary medicine to help manage menopause and other symptoms. Moderated by Darlene Gibbon, MD. FACOG, Medical Director of Gynecologic Oncology.
Other event materials can be found under the Patient Tools tab on this page: https://www.summitmedicalgroup.com/service/gynecological-oncology/
Cancer Awareness By Ms. Susmita Mitra
This is part of the HELP Talk series at HELP,Health Education Library for People, the worlds largest free patient education library www.healthlibrary.com.
For info log on to www.healthlibrary.com.
Cancer Awareness - Kaplan University Dept. of Public Healthsmtibor
Cancer awareness, including general definitions, detection, prevention, treatment, and risk factors. Emphasis on skin and prostate cancers and at-risk populations.
Various Forms Of Cancer Of Which You Should Be Aware.pdfPrudentRx Program
The various forms of cancer should be on your radar. Until a later stage of development, many cancers show no symptoms. If you notice any symptoms, you should schedule an appointment with your doctor right away.
Cancer is a difficult disease to deal with. Not only is it scary, but it can be hard to catch early on. And while there are many different types of cancer, some are more difficult to diagnose than others. In this blog post, we will explore six types of cancer that are difficult to diagnose.
Cancer strikes people of all ages, but you are more likely to get cancer as you get older, even if no one in your family has ever had cancer. The good news is that cases of cancer and death rates are going down. That means that no matter what your age, the chances of surviving cancer are better today than ever before.
Ovarian cancer is a group of diseases that originates in the ovaries, or in the related areas of the fallopian tubes and the peritoneum. Women have two ovaries that are located in the pelvis, one on each side of the uterus. The ovaries make female hormones and produce eggs for reproduction.
Do not die of colon cancer press message 2Innocent Atuhe
Colon cancer is one of the commonest cancers in Uganda. But it can be prevented. It can be easily detected using a cost effective easily accessible screening method (FOBT)
The incidence of cancer has been rising alarmingly for the last few decades. In India, more than 1200 cancer deaths are reported every day. Cancer can be removed from the body by surgery, provided it is detected early enough when the tumour is localised. Although it is extremely difficult to detect cancer in such an early stage, still the most important step in our fight against cancer remains its early detection.
For more information: www.cancertame.com
Helping Children with Cancer Feel Understood
CANSA partnered with the Hollard Insurance Group to release stories in short booklet form, to encourage children fighting cancer.
Read more:
https://cansa.org.za/helping-children-with-cancer-feel-understood/
'Feeling Sad' is a sensitively written book that explains a young boy's challenge after his mother dies from cancer, normalising his fears and helping him with ways to handle his grief. The book was written by Sally Anne Carter and illustrated by Alison Guy.
Borskanker affekteer baie Suid-Afrikaanse vroue en is die mees algemene kanker onder vroue in die land. Deur jou geesteswelstand te prioritiseer, kan die borskankerervaring meer hanteerbaar maak. KANSA verstaan dit, en bied beradingsdienste en ondersteuningsgroepe om kankeroorwinnaars en versorgers emosioneel te ondersteun.
Lees meer:
https://cansa.org.za/die-impak-van-borskanker-op-geestesgesondheid/
KANSA vier gedurende Augustus KANSA se ondersteuningsaanbiedinge. Ons lig die nuwe KANSA Inligtings- en Ondersteuningstoonbanke by sommige openbare hospitale uit wat deur personeel en opgeleide vrywilligers behartig word. KANSA het verder ’n reeks ‘Verwerking van Kanker’-plakkate ontwikkel wat beskikbaar is in Engels, Afrikaans, seSotho, seTswana, isiXhosa, isiZulu
https://cansa.org.za/ons-plaas-die-sorg-in-kansa-sorgmaand
CANSA celebrates CANSA Care Month in August to highlight its service offerings. We highlight our new CANSA Information and Support Desks at public hospitals, run by staff and trained volunteers. CANSA also developed a series of ‘Coping with Cancer’ posters in in English, Afrikaans, seSotho, seTswana, isiXhosa, isiZulu
https://cansa.org.za/putting-the-care-in-cansa-care-month
Die Kankervereniging van Suid-Afrika (KANSA) vestig die kollig op die impak van ’n kankerdiagnose op vroue, met betrekking tot vrugbaarheid. Wanneer hulle jonk is en die lewe gewoonlik pragtig en vol drome is, kan vroue wat met kanker gediagnoseer word, moeilike en onverwagse uitdagings in die gesig staar. Lees meer:
https://cansa.org.za/bewaar-hoop-gesprekke-met-vroue-kankerpasiente-oor-vrugbaarheid/
Preserving Hope: Fertility Discussions for Female Cancer Patients
CANSA highlights the impact of a cancer diagnosis on women, regarding fertility. At the peak of their youth, when life is usually a beautiful journey of dreams and possibilities, women diagnosed with cancer might meet difficult and unforeseen intersection of challenges. Find out more:
https://cansa.org.za/preserving-hope-fertility-discussions-for-female-cancer-patients/
The theme for World No Tobacco Day for 2023 is “We Need Food Not Tobacco”. The Cancer Association of South Africa (CANSA) wholeheartedly supports the World Health Organisation (WHO) campaign to create awareness around the negative consequences of tobacco farming and use of tobacco.
On 4 March 2022, International Human Papilloma Virus (HPV) Day, the Cancer Association of South Africa (CANSA) supports the International Papillomavirus Society’s (IPVS) #OneLessWorry campaign, that aims to raise awareness of the virus, and the tools to overcome it, such as screening and vaccination programmes. HPV can cause cancer and is responsible for almost half a million deaths globally each year.
#OneLessWorry #HPV #EliminateCervicalCancer #CANSACervicalCancerAwareness
Find out more:
https://cansa.org.za/cervical-cancer/
Die Kankervereniging van Suid-Afrika (KANSA) ondersteun die tema ‘Tabak – ‘n Bedreiging vir ons Omgewing’ vir Wêreld Geen-Tabak Dag (31 Mei 2022). In samewerking met die Nasionale Raad Teen Rook (the National Council Against Smoking), die Hart en Beroerte-Stigting van Suid-Afrika en die Suid-Afrikaanse Mediese Navorsingsraad, help KANSA om die nuwe Wetsontwerp op Tabakprodukte en Elektrioniese Afleweringstelsels te bevorder sodat Suid-Afrikaners die keuse het vir ‘n rookvrye lewenswyse en om ‘n einde te bring aan die bedreiging wat die gebruik van tabakprodukte vir die omgewing inhou.
https://cansa.org.za/kansa-se-kies-rookvrye-lewenswyses/
CANSA aligns itself to the theme, ‘Tobacco – Threat to our Environment’ for World No Tobacco Day (31 May 2022). Together with the National Council Against Smoking (NCAS), Heart and Stroke Foundation of South Africa and the South African Medical Research Council, it continues campaigning for the new Control of Tobacco Products and Electronic Delivery Systems Bill to be passed by Parliament, to make it easier for South Africans to choose smoke-free lives and put an end to the threat tobacco-use poses to the environment.
Read more:
https://cansa.org.za/cansa-says-choose-smoke-free-lives/
KANSA raai mense aan om ’n aktiewe, gebalanseerde leefstyl te lei en sê dat sekere leefstylveranderinge kankerrisiko kan verlaag.* Verder beveel ons aan dat mense sekere leefstylfaktore uitsny wat hulle in gevaar stel vir kanker, veral kolorektale kanker wat een van die top drie kankers** onder mans en vroue in Suid-Afrika is. Slegte leefstylkeuses kan ’n belangrike rol speel wanneer dit by verhoogte risiko vir hierdie tipe kanker kom.
#CANSAColorectalCancer #ColorectalCancerAwareness #ActiveBalancedLifestyle
Lees meer:
https://cansa.org.za/is-jou-kolon-gesond/
CANSA promotes living an active balanced lifestyle and promotes that certain lifestyle changes can lower the risk of cancer.* It further advocates cutting out lifestyle factors that can put one at risk for cancer, especially colorectal cancer which is among the top three cancers** among men and women in South Africa. Poor lifestyle choices can play a significant part, in increasing risk for this type of cancer.
#CANSAColorectalCancer #ColorectalCancerAwareness #ActiveBalancedLifestyle
Read more:
Prostaatkanker is die mees algemene kanker onder mans wêreldwyd en die nommer een kanker wat Suid-Afrikaanse mans affekteer (Nasionale Kankerregister 2017), met 1 uit 17 mans wat die risiko loop om in hul leeftyd hiermee gediagnoseer te word. Lees meer:
https://cansa.org.za/mans-takel-saam-prostaatkanker/
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists
CANSA Men's Health slideshow 2018
1. www.cansa.org.za
Toll free 0800 22 66 22
072 197 9305
071 867 3530
English,
Xhosa, Zulu,
Afrikaans
Sotho, Siswati
#MensHealth
November 2018
AFFECTING MEN IN SA
THE BIG 5 CANCERS
2. CANSA Urges Men
Not to Delay Screening
Knowledge is power and can change the lives of men
drastically if they are aware of early warning signs and
symptoms of male cancers
CANSA highlights symptoms, in the hope that men will not
delay screening
It’s of great concern that the number of men being
diagnosed with late stage cancer is on the rise
Men need to be pro-active about their health and should
recognise warning signs
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
3. CANSA Urges Men
Not to Delay Screening
We encourage monthly testicular self-examinations, annual
medical check-ups and cancer screening for early detection,
as symptoms don’t always present
until cancer has spread
Men also need to lead an active,
healthy, balanced lifestyle, cutting out
lifestyle factors that increase their
cancer risk
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
4. www.cansa.org.za
Toll free 0800 22 66 22
Prostate Cancer - Symptoms
The Big 5 Cancers
Affecting Men in SA
1 in 19* SA men will develop prostate cancer
Prostate cancer often occurs without any symptoms
Symptoms more likely if advanced:
Frequent urination, esp at night
Straining to pass urine
Painful or burning sensation during
urination or ejaculation
Leaking urine
Bloody urine/semen
Advanced cancer can cause deep
pain in lower back, hips/upper thighs
Watch video: Jereme Prins, Prostate Cancer
Survivor Encourages Early Screening & Support
*National Cancer Registry 2014
5. www.cansa.org.za
Toll free 0800 22 66 22
Prostate Cancer – Reduce the Risk
The Big 5 Cancers
Affecting Men in SA
Some risk factors such as race, family history, age can’t be helped
Eat a healthy diet:
Men who eat a lot of red meat or high-fat dairy products
appear to have a slightly higher risk
High alcohol intake increases risk
Maintain a healthy weight
Use of steroids influences development of prostate cancer
Avoid smoking
TREATMENT & PROGNOSIS: Treatment depends on age and how aggressive the
cancer is. Options include surgery, radiation therapy, chemotherapy & hormonal
therapy. The prognosis for prostate cancer is good if diagnosed early and treated.
6. Prostate Cancer – Screening
www.cansa.org.za
Toll free 0800 22 66 22
Contact your local CANSA Care Centre for information on
and bookings for Prostate Specific Antigen (PSA) screening
The Big 5 Cancers
Affecting Men in SA
Screening is done with a blood test called the Prostate Specific Antigen
(PSA) test - blood test to help detect
prostate abnormalities
CANSA recommends talking to doctor
about screening by age 50, or sooner if
you have a family history
The PSA test is often combined with a
digital rectal exam, done by a doctor
7. Colorectal Cancer – Reduce the Risk
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
1 in 79* SA men will develop colorectal cancer
Go for cancer
screenings
Eat a healthy
diet
Exercise
regularly
Maintain healthy
weight
Do not
smoke
Avoid
alcohol
Screening:
Go for regular colon
screening tests such as a
colonoscopy or a
sigmoidoscopy from age
50 - every 10 years
Some CANSA Care
Centres offer faecal
occult blood tests
(positive results require a
referral to a doctor)
*National Cancer Registry 2014
8. www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
Colorectal Cancer – Signs, Symptoms
(You can have early colorectal cancer without symptoms)
Change in bowel habits
A feeling that the bowel doesn’t empty completely
Rectal bleeding
Stomach pain
Weakness
Unexplained weight loss
Treatment & Prognosis: Treatment depends on how far the cancer has advanced.
Treatment may include surgery, radiation, chemotherapy, or a combination of these
therapies. Prognosis also depends on how far the cancer has advanced. For early (stage I)
cancer of the colon or rectum, the five year survival is about 75%
9. Lung Cancer - Symptoms
www.cansa.org.za
Toll free 0800 22 66 22
You can have lung cancer before symptoms develop.
Shortness of breath
Cough
Coughing up blood
Chest pains
Noisy breathing
Feeling very tired all the time
The Big 5 Cancers
Affecting Men in SA
Treatment & Prognosis: Treatment depends on the type of cancer, its location and how
advanced it is. Options involve surgery, radiation, chemotherapy or a combination.
Prognosis depends on whether the cancer has spread.
For cancers that have not spread, the five-year survival rate is about 50%
1 in 80* SA men will develop lung cancer
*National Cancer Registry 2014
10. Lung Cancer
www.cansa.org.za
Toll free 0800 22 66 22
Screening
Examining the lungs with a fiberoptic telescope
Sampling sputum to look for cancer cells
Doing a CT scan
If you are older than 50 and have a history of smoking or
have Chronic Obstructive Airway Disease (COPD), talk to
your doctor about screening
The Big 5 Cancers
Affecting Men in SA
Lowering of Risk
It is estimated that risk for lung cancer can be lowered in 90% of cases
through action and awareness
Smoking accounts for majority of preventable lung cancers, but non-smokers
can take action to lower their risk as well
Best way to prevent lung cancer is to not smoke & avoid second hand smoke
11. Kaposi Sarcoma (KS)
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
1 in 320* SA men will develop Kaposi Sarcoma
KS is a cancer that causes patches of abnormal tissue to grow under
the skin, in the lining of the mouth, nose and throat or in other organs
Symptoms
Skin lesions (pink to brown, brown-red or reddish purple)
A raised or slightly raised bump (nodule) or a flat area
on the skin
Swelling in the arms, legs and elsewhere due to KS causes
damage to lymph vessels
Lung, stomach and bowel problems
Anaemia, as the lesions occasionally bleed slowly
Before the HIV/AIDS epidemic, KS usually developed slowly.
In HIV/AIDS patients though, the disease moves quickly *National Cancer Registry 2014
12. Kaposi Sarcoma (KS)
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
Reduce the Risk
Avoid known risk factors that raise risk of
HIV infection:
Risky sexual practices, such as having
unprotected sex
Using intravenous (IV) needles that have
been used by someone else
Screening
To be sure that a lesion is caused
by KS, the doctor will do a biopsy
to take a small sample of tissue
from the lesion and send it to a
laboratory to be analysed.
Treatment & Prognosis:
• Treatment can be difficult due to immunosuppressed state of many of people affected.
• The doctor will recommend treatment based on patient’s general health, on where the
lesions are, how extensive they are and how many there are.
• For people with AIDS, anti-HIV medications are used against the virus. This can improve the
person’s overall health and help treat KS.
• Outlook for KS depends on the form of the disease.
• About one-third of people with classic KS develop another cancer which can be fatal.
13. Blood in your urine
Blood may change colour of
urine or show up as blood
clots
Needing to urinate
frequently
Burning pain when
urinating
Biggest risk factor is smoking
— it doubles your risk
Having a family history of
bladder cancer
Being older than 55
Bladder Cancer
www.cansa.org.za
Toll free 0800 22 66 22
Signs & Symptoms
The Big 5 Cancers
Affecting Men in SA
Risk Factors
1 in 152* SA men will develop bladder cancer
*National Cancer Registry 2014
14. Tell your doctor if you
have any symptoms or
are at a high risk
Investigations are done
based on symptoms
Tests may include
cystoscopy, biopsy,
laboratory & imaging
tests
Surgery is the most common
treatment
Additional treatments may include:
administering drugs directly into
the bladder
chemotherapy
radiation therapy
Like all cancers, prognosis depends
on finding the cancer early
For stage I bladder cancer, the 5-year
survival rate is about 90%
Bladder Cancer
www.cansa.org.za
Toll free 0800 22 66 22
Screening
The Big 5 Cancers
Affecting Men in SA
Treatment & Prognosis
15. Testicular Cancer
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
1 in 2084* SA men will develop Testicular cancer
Testicular cancer is a common cancer in men
between the ages of 15-49
Risk Factors
Having had an undescended testicle
Family history of testicular cancer
HIV infection
Personal history of testicular cancer
Age group
*National Cancer Registry 2014
16. Testicular Cancer
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
Like any other part of the body,
the testicles can be affected by
various conditions and
diseases, which can lead to
symptoms:
Lumps (Masses)
Swelling
Pain
Diagnosis of testicular
cancer is done on presence
of symptoms followed by
physical examination and
laboratory & diagnostic
tests
Survival is good if detected
and treated early
Symptoms Treatment and Prognosis
17. Testicular Cancer
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
The testicular self-examination
(TSE) is an easy way for guys
to check their own testicles to
make sure there aren't any
unusual lumps or bumps —
which can be the first sign of
testicular cancer
Try to do a TSE every month
so you can become familiar
with the normal size and shape
of your testicles, making it
easier to tell if something feels
different or abnormal in future
Cup one testicle at a time using
both hands - best performed
during or after a warm bath or
shower
Examine by rolling the
testicle between thumb and
fingers - use slight pressure
Familiarise yourself with the
spermatic cord and epididymis -
tube like structures that connect on
the back side of each testicle
Feel for lumps, change in size
or irregularities – it’s normal
for one testis to be slightly
larger than the other
18. Testicular Cancer
Testi-monials
Testi-monials, a campaign created by FCB
Cape Town for CANSA which is setting out to remove the awkwardness
around talking about testicular cancer, and drive awareness about how
important it is that men not only talk balls but take care of them too
The campaign features testicles giving their own testi-monials about
cancer and how they have been personally affected. They will give
advice on how to self-examine and help detect signs and symptoms
testimonials.co.za
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
19. CANSA also rolls out the
‘MANVan’ initiative through
funds raised from the Hollard
Daredevil event
This mobile health clinic
provides free health checks,
and support programmes,
as well as raising awareness of
male-specific cancers
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
MANVan
20. CANSA encourages men to look after their health to reduce the risk of
male cancers
CANSA ensures that South African men have access to valuable and
potentially life saving information and screening tests
CANSA offers screening for men at its CANSA Care Centres:
Blood test called the Prostate Specific Antigen (PSA) test to detect any prostate
abnormalities
Colorectal screening - Faecal occult blood test that look for microscopic blood in the
faeces, which may be sign of a growth, inflammation/bleeding in digestive system
Access CANSA’s Fact Sheets on all cancers affecting men in SA at this link:
http://www.cansa.org.za/what-cansa-believes/
What is CANSA doing to help?
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
21. CANSA is funding a study conducted by Prof Riana
Bornman (University Pretoria) that will contribute to
the understanding of prostate cancer risk, disease
progression and outcomes specifically in the
South African population
We also coordinate the IRONMAN: International
Registry for Men with Advanced Prostate Cancer
study, funded by Movember and sponsored by the
Prostate Cancer Clinical Trials Consortium. It’s a large
global study of 5 000 men, evaluating the treatment
and patient-reported outcomes for men with
advanced prostate cancer, to determine the best
way of managing advanced prostate cancer
CANSA Research on Men’s Health
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
22. Help CANSA expand its cancer screening & educational
programmes, please consider making a
donation at any of our CANSA Care
Centres country-wide
or Online at
http://www.cansa.org.za/personal-donation-options/
or Make a donation via
Snapscan or Zapper apps
on your smartphone:
What can you do to help?
www.cansa.org.za
Toll free 0800 22 66 22 The Big 5 Cancers
Affecting Men in SA
23. The Big 5 Cancers
Affecting Men in SA
www.cansa.org.za
Toll free 0800 22 66 22
Disclaimer:
Whilst the Cancer Association of South Africa (CANSA) has taken every precaution in
compiling this presentation, neither it, nor any contributor(s) to this presentation can be
held responsible for any action (or the lack thereof) taken by any person or organisation
wherever they shall be based, as a result, direct or otherwise, of information contained in,
or accessed through, this presentation.
24. www.cansa.org.za
Toll free 0800 22 66 22
072 197 9305
071 867 3530
English,
Xhosa, Zulu,
Afrikaans
Sotho, Siswati
#MensHealth
November 2018
AFFECTING MEN IN SA
THE BIG 5 CANCERS