The Meeting of G20 Agricultural Chief Scientists (MACS) was held in Punta del Este, Uruguay in October 2012. [1] High and volatile agricultural commodity prices have negatively impacted global food security by making food unaffordable for many. [2] Food production must increase 70% by 2050 to feed a growing population of over 9 billion people, but constraints like less available land and water and climate change pose challenges. [3] The MACS meeting reviewed global agricultural research initiatives and identified areas for improved coordination to strengthen food security through open data sharing and technology transfer.