(1) The document discusses the management of burn sequelae and contractures in different body regions.
(2) It provides guidance on preventing contractures through splinting, scar massage, and compressive garments.
(3) Surgical techniques for releasing contractures include Z-plasty, skin grafting, and local flaps. Intralesional steroids and silicone sheeting can also help reduce scarring.
Acute care of facial burns (7th august 2010)Tauseef Hassan
A brief overview of acute management of facial burns, specific procedures regarding excision and different skin substitutes and dressings used for biological and definitive coverage.
Acute care of facial burns (7th august 2010)Tauseef Hassan
A brief overview of acute management of facial burns, specific procedures regarding excision and different skin substitutes and dressings used for biological and definitive coverage.
A skin graft is a surgical procedure in which a piece of skin is transplanted from one area to another. Often skin will be taken from unaffected areas on the injured person and used to cover a defect, often a burn.
BURN WOUND ASSESSMENT by Priya Malik ( M.Pharm)priyamalik43
BURN WOUND :
Burn injuries can take up to 10 days to truly present the depth and extent of injury so reassessment is vital. As burn injuries heal accurate wound assessment will ensure wound management is altered as needed to ensure appropriate wound care continues to be delivered to the patient. its also based on the severity of burn cause.
Pressure sores are localized areas of tissue breakdown in skin and/or underlying tissues that develop when persistent pressure between a bony site and underlying surface obstructs healthy capillary flow.
Constant external pressure over 70 mm Hg for 2 hours produces irreversible ischemic changes.
Synonyms : Pressure ulcer, Decubitus ulcer,
Bed sore.
There are two main categories of burn surgery: acute and reconstructive. ... It is delivered by a team of trauma surgeons (General Surgeons) that specialize in acute burn care. Complex burns often require consultation with plastic surgeons, who assist with the inpatient and outpatient management of these cases.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
4. ❏ total 2º and 3º burns > 10% TBSA in patients < 10 or > 50
years of age
❏ total 2º and 3º burns > 20% TBSA in patients any age
❏ 3º burns > 5% TBSA in patients any age
❏ 2º or 3º burns with threat of serious functional or cosmetic
impairment (i.e. face, hands, feet, genitalia, perineum, major
joints).
5. ❏ inhalation injury (may lead to respiratory distress)
❏ electrical burns (internal injury underestimated by
TBSA)
❏ chemical burns posing threat of functional or
cosmetic impairment
❏ burns associated with major trauma
6. Focus of burn treatment is then shifted to the definitive
burn wound treatment and to the general support of the
patient, which include:
Wound care and coverage
Nutritional support
Infection diagnosis and management
Rehabilitation and management of burn wound
sequale
7. Full-thickness circumferential burns result in the formation
of a tough, inelastic mass of burnt tissue (eschar).
The eschar, may due to this inelasticity, results in the burn-
induced compartment syndrome.
This is caused by the accumulation of extracellular and
extravascular fluid within confined anatomic spaces
The excessive fluid causes the intracompartmental pressure
to increase, resulting in collapse of the contained vascular
and lymphatic structures and, hence, loss of tissue
viability.
8. The presence of a circumferential eschar with one of
the following:
Impending or established vascular compromise of
the extremities or digits.
Impending or established respiratory compromise
due to circumferential torso burns
9. Neurovascular integrity should be monitored frequently
and in a scheduled manner.
Capillary refilling time, Doppler signals, pulse oximetry,
and sensation distal to the burned area should be checked
every hour.
Limb deep compartment pressures should be checked
initially to establish a baseline.
10. Subsequently, any increase in capillary refill time,
decrease in Doppler signal, or change in sensation
should lead to rechecking the compartment pressures.
Compartment pressures greater than 30 mm Hg
should be treated by immediate decompression via
escharotomy and fasciotomy, if needed.
11. When escharotomy is required in a patient with a
circumferential chest wall burn, it is performed in the
anterior axillary line bilaterally. If there is significant
extension of the burn onto the adjacent abdominal
wall, the escharotomy incisions should be extended to
this area and should be connected by a transverse
incision along the costal margin
12.
13. Local anesthesia is unnecessary because third- degree
eschar is insensate; small doses of intravenous
narcotics may be utilized to control anxiety.
The incision, which must avoid major nerves, vessels,
and all tendons should extend through the eschar
down to the subcutaneous fat.
Escharotomy is rarely required within the first 6 h
postburn .
14.
15.
16.
17.
18.
19.
20. Treatment planning depends on the assessment of the
following factors:
• Patient’s general condition and co-morbid factors
• Patient age
• Burn depth
• Burn size
• Anatomical distribution of injury
21. Treatment optionBurn depth
1-Topical antimicrobials
2-Biological dressings e.g human
placenta
3-Skin substitutes e.g Biobrane®
5-exposure
Small /medium sized superficial
partial thickness wound (< 40%
TBSA)
1-Allograft
2-Xenograft
3-Topical antimicrobials
Large superficial partial thickness
injury(> 40% TBSA)
excision and grafting
Versus
Topical antimicrobials
Deep partial thickness injury
(small and large )
invariably
require excision and skin grafting.
Full thickness injury
22. DisadvantagesAdvantagesTopical Agents
Lack of penetrationPainlessSilver Sulfadiazine
Painful, Carbonic
anhydrase inhibitor
PenetratesMafenide Acetate
Limited penetrationBroad spectrumSilver Nitrate
Impairs wound
healing in high
doses
Broad spectrumSodium
Hypochlorite
29. There are numerous products available and can be
differentiated to those that provide temporary wound
cover while the underlying wound re-epithializes or
is ready for autografting (i.e., Biobrane®,
Dermagraft TC®) and those that close the wound
and help reconstitute part of the resultant skin
(Integra®).
30.
31. usually harvested from cadaveric donors after
appropriate donor selection and screening for
communicable disease, and consent from relatives
has been obtained.
In order of preference of allograft take on the excised
burn wound, fresh allograft is by far the best followed
by cryopreserved, glycerolized, then freeze-dried.
Allograft skin can also be obtained from living donors,
usually parents or relatives of burned children
32.
33. Skin from different species can be used for temporary
physiological wound closure.
Pig skin is commonly used and is commercially
available.
34. There are two methods of management of the burn
wound with topical agents.
In exposure therapy, no dressings are applied
over the wound after application of the agent to the
wound twice or three times daily. This approach is
typically used on the face and head. Disadvantages are
increased pain and heat loss as a result of the
exposed wound and an increased risk of cross-
contamination.
35. In the closed method, an occlusive dressing is
applied over the agent and is usually changed twice
daily. The disadvantage of this method is the potential
increase in bacterial growth if the dressing is not
changed twice daily, particularly when thick eschar is
present. The advantages are less pain, less heat loss, and
less cross-contamination. The closed method is generally
preferred.
36. In vitro culturing of epidermal cells (keratinocytes)
produced a permanent skin and grafted onto a burn
wound bed, closing massive wounds when donor
sites were limited.
The first successful grafting was reported in children
in 1986.
37. When the patient is admitted, a 1-cm skin biopsy
specimen is usually sent to a commercial laboratory
for culturing.
Three weeks later 5- by 5-cm 2 sheets of cultured
cells are delivered.
CEAs are expensive.
Engrafted CEAs are poorly adherent and extremely
fragile for months after application.
38.
39.
40.
41. Excisional procedures should be performed as early
as possible after the patient is stabilized.
This allows the wound to be closed before infection
occurs and, in extensive burns , allows donor sites to
be recropped as soon as possible.
Cosmetic results are better if the wound can be
excised and grafted before the intense inflammatory
response associated with burns becomes well
established.
42. Any burn projected to take longer than 3 weeks to
heal is a candidate for excision within the first
postburn week.
Wound excision is adaptable to all age groups, but
infants, small children, and elderly patients require
close perioperative monitoring.
43. Excision can be performed to include the burn and
subcutaneous fat to the level of the investing fascia
(fascial excision), or by sequentially removing thin
slices of burned tissue until a viable bed remains
(sequential excision).
44. The principle is to shave very thin layers of burn eschar
sequentially until viable tissue is reached.
The burn can be removed with a variety of instruments,
usually power- or hand-driven dermatomes.
45. Slices are taken until a viable bed of dermis or
subcutanbed does not bleed briskly, another slice of the
same depth eous fat is reached.
If inspection of the dermal or fatty bed reveals a surface
that appears gray or dull rather than white and shiny, or
if there is evidence of clotted vessels, the excision should
be carried deeper.
46. Any fat that has a brownish discoloration, has blood
staining, or contains clotted blood vessels will not support
a skin graft and must be excised until the bed contains
uniformly yellow fat with briskly bleeding vessels.
Bleeding is controlled with sponges soaked in 1:10,000
epinephrine solution applied to the excision bed for 10
min.
Continued bleeding is then controlled with an
electrocautery.
47. Fascial excision is reserved for patients with very
deep or for patients with very large, life-threatening,
full-thickness burns.
48. (1) It results in a reliable bed of known viability.
(2) Tourniquets can be routinely used for extremities.
(3) Operative blood loss is less than with sequential
excision.
(4) Less experience is required to ensure an optimal
bed.
49. (1) The operative time is longer.
(2) There may be severe cosmetic deformity,
especially in obese patients.
(3) There is a higher incidence of distal edema when
excision is circumferential.
50. Skin graft junctures should be avoided over joints,
and grafts should be placed transversely when
possible.
Thick skin grafts yield a better appearance than thin
skin grafts so should be used on the face, neck, and
other cosmetically important areas.
51. The resultant donor sites can be overgrafted with thin
skin grafts to minimize hypertrophic scarring of the
donor site.
Whenever possible, cosmetically important areas
should be grafted with sheet skin grafts.
52. Although meshed skin grafts provide cover with
excellent function, the meshed pattern persists as a
permanent reminder of the burn.
Adjacent pieces of skin graft should be approximated
carefully.
While staples are adequate for areas in which
cosmetics is not an issue, for critical areas, such as
the face, suturing the edges together is preferred.
53.
54.
55.
56.
57.
58.
59.
60.
61. Superficial burns of the face should be left exposed.
The face is washed twice daily with a mild soap and
water, and a thin layer of a bland ointment
(bacitracin) is applied to the open wounds to prevent
drying.
62. Superficial burns of the ear should be treated with a
bland ointment.
Deeper injuries must be treated with topical
antibiotics; excessive pressure may cause chondritis,
and should be avoided.
63. Suspected corneal burns should be stained with
fluorescein for confirmation of diagnoses.
Superficial corneal burns should be treated similarly
to corneal abrasions, with vigorous irrigation, the
application of ophthalmologic antibiotic ointment,
and eye patching.
64. Superficial burns of the hand should be elevated for
24 to 48 h to minimize swelling.
Circumferential hand burns may require
hospitalization for observation of adequate
circulation.
Range-of-motion exercises should begin as soon as
possible after injury.
.
65. Although burns of the feet are painful, walking and
range-of-motion exercises should be performed.
Crutches should not be allowed.
To prevent edema, burned feet should be elevated
when the patient is not walking or exercising.
An elastic bandage should be applied over the
wound dressing when the patient is walking or
sitting, but it should be removed at night when the
feet are elevated.
66. Perineal burns frequently require hospitalization for
24 to 48 h for observation of urinary obstruction
secondary to edema.
Minor perineal burns can be treated with a bland
ointment.
Extensive superficial perineal burns, e.g., pediatric
bathtub scald injuries, are best treated with topical
(silver sulfadiazine), utilizing a diaper as the wound
dressing.
67. To prevent contractureAim
Extended (no pillow)Head and neck
apply eye ointment 3
times daily
Eyelids
apply moisturizing agent
(Vaseline)
Lips
apply maintainerLip commissure
elevation and apply splint
in functional position
Hand
(abducted )Axilla
dorsiflexed with foot
support.
Foot
68.
69.
70.
71.
72. 1- Early release of tension over flexion creases of
joints. Tension in a scar encourages hypertrophy, so
that releasing it by grafting or local flaps may
prevent its occurrence.
2- Continuous scar massage, after application of skin
emollient, can be quite effective.
73. 3- Pressure on maturing scar tissue, appears to
reduce the incidence of hypertrophic changes. Such
pressure is most likely maintained by compressive
garments for 24hrs./day, for at least six to twelve
months.
74. 1- The release of the contracture by re-arranging
the tissues by local flaps (e.g.: Z- plasty) or by the
application of skin graft.
2- Intralesional steroid injection
(e.g.: triamcinolone acetonide; 1-2 cc of 40 mg./cc
at one or two weeks interval.). It inhibits collagenase
inhibitors causing degradation of collagen, thus
decreasing dermal thickening.
75. 3- Application of silicone gel sheet as an
occlusive dressing.
Ideally it should be placed 24hrs./day for about a
year.
76. 5- Laser therapy :
The modalities are :
- Pulse-dyed laser ----- microvascular thrombosis
- CO2 laser & Argon laser----- collagen shrinkage
through heating.
- Nd-YAG laser----- inhibits collagen metabolism
and production.
However the recurrence rate with laser therapy is
high.
77. 6- Interferon therapy : The newest therapeutic
modality on the horizon is intralesional injection Of Inter
They reduce fibroblast synthesis and collagen
type I, III and possibly IV and increase the
collagenase activity.
78. Management of burn sequelae
in specific regions
1- Head and Neck
2- Upper extremity
3- Lower extremity
4- Trunk
79. 3- Reconstruction :
a- Minor defect: advancement and rotation
of adjacent scalp flaps will be enough to
fill the defect.
b- Moderate defect: Tissue expansion is
the final treatment of choice. This allows
the area to be reconstructed with like
tissue and with no donor defect.
80.
81.
82.
83.
84.
85. c- Extensive defect: This is a difficult situation.
Defects in this range may be too large to be
corrected by tissue expansion. If periosteum is
intact, a skin graft is applied. Otherwise free tissue
transfer is required. The most common flaps are the
omentum and the latissimus myocutaneous flaps.
86. 1- The forehead : is best resurfaced with a
single sheet of split thickness skin graft.
With bony exposure or destruction, flap
reconstruction is indicated.
2- The cheeks : the best is tissue expansio
from adjacent non-injured tissue (e.g.: nec
Thin free flaps may be considered (e.g.: rad
forearm flap). Others describe the use of a
large full-thickness graft as one aesthetic
87. Eye lid reconstruction :
Indications : exposed cornea, contractor
ectropion of upper and/or lower eye lid and
contractures at the canthi regions.
1- Total loss of eye lids : the exposed cornea can
be covered by mobilizing the conjunctiva which is
covered with skin graft. Later on the lids can be
reconstructed with local flaps (e.g.: cheek flap or
median forehead flap
with septal
mucoperichondrial graft
as lining).
88. 2- Ectropion :
we have to distinguish between :
a- primary ectropion where the deep burn affects
the eye lids directly. The treatment is release of the
contrature and application of thick split thickness
graft to the upper eye lid and a full thickness graft to
the lower eye lid.
89. b- secondary ectropion, due to contracture of
forehead, cheek or neck pulling on the eye lids.
Treating the cause will alleviate the condition.
90. Eye brow reconstruction :
* Loss of the hair may be
compensated by the simple
simulation done by an eye brow
pencil ( specially in women ).
However surgical reconstruction
of the eye brow may be done
through :
91. 1- Hair transplantation: single hair transplantation is
better than a punch graft.
2-Hair-bearing flap from the temporal scalp. It is
based on the superficial temporal artery and it is an
island flap.
92. 3- Strip graft taken anywhere from the hairy
scalp with the dimension and shape of the eye
brow. Care is taken :
- not to exceed 4 mm. in width.
- not to injure the hair follicles during elevation of
the flap by the scalpel.
- the direction of the hair should be oriented from
medial to lateral.
93. Lip and mouth reconstruction :
1- Extensive scarring of the upper or
lower lip:
excision and full thickness graft within
the
aesthetic unit of the involved lip.
2- Microstomia (oral commissure
contracture):
corrected by full thickness incisions at
each angle
of the mouth as far as a line dropped
vertically
from the pupil of the eye. Then the
oral mucosa
94. is mobilized and everted onto the lip skin,
forming
a new commissure. Some overcorrection is
generally advisable.
95. Nasal reconstruction :
1- Total destruction of the nose requires :
a- Flap reconstruction either
regional, like the forehead flap,
or distant by microvascular transfer.
b- Prosthetic reconstruction.
2- Unacceptable hypertrophic or hypopigmented
scars over a large surface of the nose may be
treated by dermabrasion, either mechanical or by
laser, and application of a single sheet of skin
graft within the nasal aesthetic units.
96. 3- Alar rim reconstruction is done using a composite
graft from the ear.
4- Nostril stenosis is treated by release and skin
grafting. Splints must be worn for at least six months
after surgery to prevent recurrence.
5- Web contracture between columella and upper lip,
may be released by V-Y advancement flap.
97. Ear reconstruction:
- Indications: Partial or total loss of the external
ear.
- Classification: Help to determine the treatment.
Mild defect: loss of helix and upper part of the
auricle, without extensive scarring.
Moderate defect: concha nearly normal; upper h
of the ear missing; antihelix and its posterior cr
missing.
Severe defect: remnant of concha; local soft tiss
scarred; external ear orifice normal or stenosed.
98. Head & neck reconstruction
(Ear reconstr.)
Treatment :
1- Total absence of the auricle :
- Surgical reconstruction using a costochondral
graft, as described for microtia.
- Osteointegrated prosthesis.
2- Subtotal absence of helical rim :
- Local flap reconstruction is preferred.
- When the entire helix is missing, a tubed
cervical skin flap is used.
99. 3- Ear lobe deformity:
- Adherence of the ear lobe to the neck is the main
deformity. Z-plasty or local flaps are generally
sufficient for correction.
4- Meatal stenosis :
- Splinting may be used as a preventive measure
and may eliminate the need for surgical
correction
- After release, use local flaps if available. If not
use skin graft.
- A conformer is worn by the patient for 4 - 6
months to prevent recurrence.
100. * Treating established contractures :
1- Mild cases: mild scar bands can generally be
corrected surgically by using local flaps or Z-
plasties.
2- Moderate cases: contractures involving 1/3 - 2/3
of anterior neck, can be treated using tissue
expansion. The unscarred lateral aspects of the
neck are expanded.
101. 3- Severe cases: contractures involving more than
2/3 of the anterior neck, are better treated by
release and split thickness skin graft or distant flap
by microvascular technique. Local flaps are not
adequate.
102. * Treating established contractures :
1- Scar bands and minor contractures are bett
treated by local flaps e.g.: Z-plasty or V-Y plas
They may be combined with the application of
skin graft, kept in place by tie-over dressing.
103. * Treating established contractures :
2- Moderate contracture may be released and the
defect filled with a latissimus dorsi fasciocutaneous
flap.
104. * Treating established contractures :
3- Severe contracture, producing large defect on
release, are best treated with skin graft.
105. Plaster of paris is applied at the
end of the operation where the
joint is kept as fully abducted
as possible.
Splintage should be maintained
for several weeks until the
patient can put the joint
through a full range of
movement.
107. Management of clinically septic
patien
1) Support of cardiopulmonary and
G.I. systems.
2) Eschar debridement.
3) Empiric antibiotic.
4) Send for culture/sensitivity.
5) Adequate fluid to maintain
intravascular volume.
6) Invasive monitoring.
7) Change in frequency of dressing.
8) Change in topical antibiotic.
t
108. Before the availability of penicillin, streptococci and
staphylococci were the predominant infecting
organisms.
By the late 1950s, gram-negative bacteria (
Pseudomonas species) had emerged as the dominant
organism causing fatal wound infections in burn
patients.
109. All burn wounds become contaminated soon after
injury with the patient's endogenous flora or with
resident organisms in the treatment facilities
The likelihood of septicemia increases in proportion
to the size of the burn wound.
110. One result of the prolonged survival of severely burned
patients in critical care units, made possible by modern
patient support techniques, is that the respiratory tract has
become the most common locus of infection
A diagnosis of pneumonia is confirmed by the presence of
characteristic chest radiograph patterns, and the presence of
offending organisms and inflammatory cells in the sputum
For the diagnosis of bronchopneumonia, analysis of
sputum samples may be adequate
111. Suppurative thrombophlebitis is a major cause of
sepsis in burn patients, occurring in up to 5 percent of
patients with major burns.
112. Endocarditis is occasionally the cause of occult sepsis in
burn patients, and its incidence continues to rise with the
increasing use of intravenous catheters for hemodynamic
monitoring. Endocarditis should be suspected in patients
with positive blood cultures and no other identifiable
source of bacteremia. These patients should be examined
repeatedly
by echocardiography until the source of the septicemia is
identified.
113. Most patients with burns greater than 20 percent
TBSA require indwelling urinary catheters to guide
fluid resuscitation.
Aseptic techniques of insertion and catheter care, the
use of a closed drainage system, and the removal of
the catheter at the earliest clinically indicated time are
effective measures for preventing urinary tract
infections.
114. The pinna of the ear is composed almost entirely of
cartilage with minimal blood supply and is vulnerable
to infection.
It is a rare complication.
When chondritis does occur, conservative approach
with drainage of the helix centrally, in an attempt to
preserve the outer cartilages, is usually successful.
115. The nutritional effects of the hypermetabolic response
to thermal injury are manifested as exaggerated energy
expenditure and massive nitrogen loss.
Nutritional support is directed primarily toward
supply of calories to match energy expenditure and
provision of nitrogen to replace or support body protein
stores.
116. Caloric requirements in adult burn patients are
calculated using the Curreri
formula, which calls for 25 kcal/kg/day plus 40
kcal/% TBSA burned/day.
117. Patients with burns under 25 percent TBSA that are
not complicated by facial injury, inhalation injury, or
malnutrition, and are not associated with psychological
difficulties can usually be maintained on high-calorie,
high-protein diets ingested orally.
The nutritional requirements of patients with large
burns cannot be met by the oralroute alone, and these
patients should be fed gastrointestinally or
nasoenterally.
118. A functionally intact alimentary tract always should
be used.
Enteral nutrients seem to maintain the integrity of the
gastrointestinal tract, and increased hepatic protein
synthesis may reduce the incidence of bacterial
translocation from the gut.
119. An oral diet preserves gut mucosal mass and
maintains digestive enzyme content; parenteral feeding
results in decreased mucosal cell turnover.
Total parenteral nutrition should be instituted when
enteral feedings alone cannot provide adequate
nutritional support