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1. 1
A Patient’s Guide to Treatment

2. The BOTOX®
Cosmetic “WOW” Commercial

3. BOTOX®
Cosmetic Overview
 History of BOTOX®
Cosmetic
 How lines and wrinkles can form
 How BOTOX®
Cosmetic works
 What to expect from a BOTOX®
Cosmetic procedure

4. BOTOX®
Cosmetic Overview [cont’d]
 Dramatic results with no downtime
 Dramatic results within a week
 Dramatic results that people notice
 Dramatic results that look natural
 BOTOX®
Cosmetic safety
 Summary

5. BOTOX®
(Botulinum Toxin Type A)—
10 Years of Success
 BOTOX®
is the only one of its type with over 10 years
of success in treating patients with a variety of conditions
 Approved in 70 countries for a broad range of conditions
 Currently being investigated in the US for the treatment of
many medical conditions

6. BOTOX®
Cosmetic—
NOW FDA APPROVED!
 With dosing specific to treat frown lines, BOTOX®
is
now available as BOTOX®
Cosmetic
 BOTOX®
Cosmetic is a highly effective procedure that
can dramatically reduce wrinkles between your brows

7. How Lines and Wrinkles Can Form
 Movement of brow muscles causes the skin to crease
corrugator muscles corrugator muscles
procerus muscle
 As skin becomes less elastic over time, repeated frowning
creates visible lines and wrinkles

8. Ricki
“My daughter said that I was looking older
and that I looked unhappy—even when
I was smiling. I realized that I was looking
older because of the frown lines that were
developing between my brows.”

9. How BOTOX®
Cosmetic Works
 BOTOX®
Cosmetic is a natural and purified protein that
relaxes the muscles by blocking nerve impulses
With a few tiny injections, BOTOX®
Cosmetic blocks the release of
acetylcholine, the chemical that
causes muscles to contract.
 Once the muscles are at rest, the skin becomes smoother,
creating a more natural and relaxed appearance

10. What to Expect From a
BOTOX®
Cosmetic Procedure
 This simple 10-minute procedure consists of a few
tiny injections
 No anesthesia is required, although you may be advised
to numb the area with a cold pack or anesthetic cream
prior to injecting
 Discomfort is minimal and brief—most patients compared
the sensation to a bug bite
 There may be slight temporary bruising at the injection site,
which can easily be covered up with makeup
Advance to Video Advance to Next Slide

11. Injection Video

12. Dramatic Results…
With No Downtime
before after
Unretouched clinical photos taken at maximum frown before BOTOX®
Cosmetic
and 30 days after BOTOX®
Cosmetic treatment.
 After the procedure, you can resume normal activity
immediately

13.  You’ll see a marked improvement within days that may continue
to improve for as long as a week
 In clinical studies, the majority of people (82.5%) reported an
improvement in the lines between their brows after a week
(n=405)
 The effects of BOTOX®
Cosmetic last up to 4 months
before after
Dramatic Results…
Within a Week
Unretouched clinical photos taken at maximum frown before BOTOX®
Cosmetic
and 30 days after BOTOX®
Cosmetic treatment.

14. Donna
“I would definitely do it again. I make sure
to schedule treatments every 3 to 4 months.
I’m pretty diligent about it because I feel
like it makes a difference.”

15. Dramatic Results…
That People Notice
 After 30 days, nearly 90% of BOTOX®
Cosmetic patients
surveyed rated the improvement in their brow lines as moderate
to better
 For many patients, BOTOX®
Cosmetic virtually “erases” these
lines
Unretouched clinical photos taken at maximum frown before BOTOX®
Cosmetic
and 30 days after BOTOX®
Cosmetic treatment.
before after

16. Ricki
“The results have been terrific.
[BOTOX®
Cosmetic] has virtually removed
the frown lines between my brows.”

17. Dramatic Results…
That Look Natural
 With BOTOX®
Cosmetic, you will not look “like you’ve
had work done.” You can still frown, smile, or look surprised
without the wrinkles and creases
Donna
“I get compliments on my appearance, but nobody
can pinpoint exactly what I’ve done. I feel good
about not doing something that’s very obvious,
because I like appearing natural. That’s important
to me.”

18. BOTOX®
Cosmetic Safety
 Contraindicated in the presence of infection at the proposed
injection site(s) and in individuals with known hypersensitivity
to any ingredient in the formulation
 Safe and effective. The most common side effects are
headache, respiratory infection, flu syndrome, temporary
eyelid droop, and nausea
 Administered at very low doses, and the effects are usually
confined to the injected area; it does not travel throughout
the body

19. BOTOX®
Cosmetic Safety
 Less frequently occurring (<3%) adverse reactions included pain
in the face, redness at the injection site, and muscle weakness
 These events are thought to be associated with the injection
and occurred within the first week
 Full prescribing information has been provided to your doctor

20. BOTOX®
Cosmetic—Summary
 BOTOX®
Cosmetic is a simple, 10-minute procedure that can
dramatically reduce your frown lines
 No recuperation time is required
 You’ll see a marked improvement within days, and effects last up
to 4 months
 Treatment is safe and effective. The most common side effects
are headache, respiratory infection, flu syndrome, temporary
eyelid droop, and nausea
Questions to ask your doctor:
 Am I a good candidate for BOTOX®
Cosmetic treatment?
 What is your experience in using BOTOX®
Cosmetic for
frown lines?
 When can I expect to see results and how long will they last?