- BOTOX Cosmetic is a purified protein that temporarily treats moderate to severe frown lines between the brows through tiny injections that block nerve impulses and muscle movement. - Results are typically seen within days and can last up to 4 months, with minimal side effects like temporary eyelid drooping. - It is a popular, non-surgical procedure that produces natural-looking results without downtime.

1. A Patient’s Guide to BOTOX ® Cosmetic Emil Chynn, MD, FACS, MBA Dartmouth/Columbia/Harvard/Emory/NYU-trained Park Avenue Laser 102 East 25 th Street, NY, NY 10010 Full prescribing information has been provided to your doctor.

2. Why get Botox/Juvaderm from an Eye Surgeon? Both products by Allergan, the eye company Both used by Eye MDs longer than any other MD Dr. Chynn performed Botox at Harvard in 1995! 1 st used hyaluronidase/Juvaderm in 1993! Has more years of experience with each product than any plastic surgeon/dermatologist

3. BOTOX ® Cosmetic - Outline History of BOTOX Cosmetic (initial use by Eye MDs) How lines and wrinkles can form between the brows How BOTOX ® works What to expect from a BOTOX ® Cosmetic procedure What you should know before getting BOTOX ®

4. BOTOX ® Cosmetic Overview Results with no downtime Results seen in days / can last up to 4 months Results people notice Results that look like you haven’t “had work done” Important BOTOX ® Cosmetic Information BOTOX ® Cosmetic summary Continued

5. BOTOX ® Cosmetic The only FDA-approved prescription treatment For the temporary treatment of moderate to severe frown lines between the brows in people ages 18 to 65 Almost 3.3 million BOTOX ® Cosmetic procedures were performed in 2005 alone 1 After this presentation, we will help you decide if BOTOX is right for you! 1. The American Society For Aesthetic Plastic Surgery, 2005. One-of-a-Kind Treatment

6. How Lines and Wrinkles Can Form Between the Brows Movement of brow muscles causes the skin to crease Skin becomes less elastic over time; repeated frowning creates wrinkles between brows (the clinical term is glabellar lines) Corrugator muscle Corrugator muscle Procerus muscle

7. Patient Testimonial “ I realized my frown lines had grown strong enough that even in my relaxed state, they were fairly pronounced.”

8. How BOTOX ® Cosmetic Works BOTOX ® Cosmetic is a purified protein that smoothes the muscles by blocking nerve impulses With a few tiny injections, BOTOX ® Cosmetic blocks the release of acetylcholine, which causes muscles to contract With less movement, the skin surface gradually smoothes out and lines begin to fade!

9. What to Expect From a BOTOX ® Cosmetic Procedure Simple 10-minute procedure consists of a few tiny injections Results typically seen in days and will continue to improve during the first week after treatment (results may vary) No anesthesia injections required Your doctor will numb the area with anesthetic cream Minimal and brief discomfort There may be slight temporary bruising at the injection site This can be easily covered up with makeup The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness and/or bleeding/bruising may be associated with any injection Advance to Video Advance to Next Slide

10. Important Safety Information Serious heart problems and serious allergic reactions have been reported rarely If you think you’re having an allergic reaction or other unusual symptoms, such as difficulty swallowing, speaking, or breathing, call your doctor immediately The most common side effects following injection include temporary eyelid droop and nausea Localized pain, infection, inflammation, tenderness, swelling, redness and/or bleeding/bruising may be associated with the injection Patients with certain neuromuscular disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious side effects

11. What You Should Know Before a BOTOX ® Cosmetic Procedure To ensure the best treatment outcome: Your physician should inject 20 units (1/5 of an entire vial) in the glabellar region between the brows Dr. Chynn will give you the ENTIRE DOSE for best results! Dosage amount is not based on the # syringes used! Dr. Chynn follows Allergan directions on dilution: 2.5 mL sterile saline for entire vial = 100 units Botox each 0.5 mL syringe = 20 units Botox

12. Results… Un-retouched clinical photos taken at maximum frown before and 14 days after treatment with BOTOX With No Downtime Before After Before After

13. Results… You’ll see improvement within days that will continue to improve during the first week after treatment Results will last 3-6 months (longer if younger, had it before, finer lines) 89% of men and women saw significant improvement in their appearance of brow frown lines at 1 month Un-retouched clinical photos taken at maximum frown before and after BOTOX ® at day 14. Seen in Days and Can Last Up to 4 Months 1. BOTOX ® Cosmetic Prescribing Information. Before After

14. Patient Testimonial “ I’ve had BOTOX 3 times, and am so happy with my results I’m going to make it my routine every 3-4 months to maintain my new look!”

15. The Results Speak for Themselves! The most popular MD-administered cosmetic procedure BOTOX ® Cosmetic has been the #1 MD-administered cosmetic procedure in the US for 4 years in a row! BOTOX ® is the Most Popular Non-surgical, Physician-Administered Cosmetic Treatment Before After

16. Patient Testimonial “ I see a difference. . . but more importantly, friends and family have seen a lot of difference!”

17. Terrific Results… You can still frown, smile, or look surprised without wrinkles / creases between your brows “ I am still able to smile and look natural and warm, after Botox by Dr. Chynn—and as an actress, I’m happy with that!” Without Looking Like You’ve “Had Work Done”

18. Important Safety Information Serious heart problems and allergic reactions have been reported rarely If you think you’re having an allergic reaction or unusual symptoms such as difficulty swallowing, speaking, or breathing, call your doctor immediately The most common side effects following injection include temporary eyelid droop and nausea Localized pain, infection, inflammation, tenderness, swelling, redness, or bleeding/bruising may be associated w. injection Patients with neuromuscular disorders such as ALS, MG (myasthenia gravis), or Lambert-Eaton syndrome may be at increased risk of serious side effects

19. BOTOX ® Cosmetic—Summary BOTOX ® Cosmetic is a simple, 10-minute procedure that will reduce the appearance of moderate to severe frown lines between the brows, crow’s feet, and smile (marionette) lines within days No downtime Noticeable improvement within days and results that will last 3-6 months, depending on age, severity, frequency The most common side effects are temporary eyelid droop and nausea

20. Questions to Ask Dr. Chynn Am I a good candidate for BOTOX ® Cosmetic treatment? What is your experience in using BOTOX ® Cosmetic for frown lines, crow’s feet, smile lines? What kind of results can I expect based on my personal profile? Do you suggest augmentation with Juvaderm filler (if my lines are very deep) – ask us about Juvaderm (hyalaronidase = organic = purified rooster combs!)

21. Thank You Emil Chynn, MD, FACS, MBA Park Avenue Laser ©2006 Allergan, Inc., Irvine, CA 92612 ® Marks owned by Allergan, Inc.