The document outlines the concept of the modern Columbian exchange as a manifestation of globalization that introduces challenges, particularly in managing complex interconnections of technology, lifestyles, and diseases. It emphasizes the importance of leveraging human intelligence and big data to tackle these complexities, proposing new strategies for data utilization and real-time decision-making. The authors call for immediate action to transform available data into actionable knowledge to enhance community well-being and scientific advancements.