This study investigated CD36 gene status in north Indian subjects with type 2 diabetes (T2DM) by screening for deletions of exons 3, 4 and 5 and certain polymorphisms. Blood samples were taken from 300 T2DM patients and 100 healthy controls. Biochemical parameters and DNA extraction were performed, and exons 3-5 were analyzed via PCR. Deletions of exons 4 and 5 were identified in T2DM patients but not controls. The study aims to further analyze genetic factors and deletions related to the CD36 gene in T2DM patients in north India.