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Harold Tagalog was assigned a task for his Biology 104 Genetics class to complete a matrix providing information on seminal findings and breakthroughs in genetics, including the date, discovery or invention, contributor, and impact. Some of the entries in the matrix include Barbara McClintock discovering transposable elements or "jumping genes" in 1940 and their role in species growth and evolution. Patrick Brown developed genomic mismatch scanning in 1993 to more quickly identify genes in families. Victor Dzau tested gene alterations on vein grafts in 1994 which helped make veins resistant to clogging after heart bypass surgery. The task is due by January 30, 2023.
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![Name: Harold Tagalog Date: Jan. 29, 2023
Year & Sec: BSBIO- 2a
BIOLOGY 104 GENETICS
2ND
SEM. SY 2022-2023
TOPIC: Introductory
LEARNING OBJECTIVE: to point out significant research findings [which couldz be tools and approaches/techniques] and scientists/researchers
responsible for these contribution in enhancing our current understanding of the field of genetics
TASK [1]: Research on the information as stated in the heading of each column and fill up the given matrix.
Date [in
chronological
order]
Seminal Findings or
Breakthrough
discoveries/Inventions
[word or phrase only]; provide
a picture if tools/devices
Contributor/s or Maker or
Researchers/Scientist/s
Responsible
[name/s and picture]
What made this breakthrough a turning point for the field of
genetics?
[not to exceed 5 sentences]; 2 points each
1 1940 Discovering genetic
transposition ("jumping
genes").
Barbara McClintock
Transposable elements (TEs), also known as "jumping genes,"
are DNA sequences that can move from one location on the
genome to another. According to research, these sequences are
essential for the species' growth, development, and evolution. A
quarter of them, for example, are in charge of working on the
genetic switches that turn on and off and can alter protein
synthesis and gene action.](https://image.slidesharecdn.com/bio104task1tagalogh-230206103554-baeecb1e/85/Bio-104-Task-1_tagalog-H-doc-1-320.jpg)
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other problems introduced by such behavior, but ignore these for answering this question).
(d) Suggest a possible confounding factor (other than age, income, or religion) and clearly explain
why you think it might be a confounding factor.
4. A randomized, controlled, double-blind study published in March, 2008 shows the well-known “placebo
effect” works even better if the placebo costs more. In the study, volunteers were given an electric
shock and took a pill. Volunteers in the treatment group were told it was an expensive painkiller,
while those in the c.
The Future Of Human Evolution Essay
The document discusses evidence that supports evolution being real, including fossil records, embryology, comparative anatomy, molecular biology, and direct observation. Fossil records show remains of ancestral species and how creatures have changed over time. Embryology and comparative anatomy demonstrate homologous and analogous structures between species. Molecular biology reveals DNA comparisons between past and present species. Direct observation allows seeing how species adapt in their environments. Taken together, this evidence substantiates evolution as occurring through genetic changes in populations over generations in response to their environments.
The mechanisms of epigenetic inheritance: how diverse are they?
Although epigenetic inheritance (EI) is a rapidly growing field of modern biology, it still has no clear place in fundamental genetic concepts which are traditionally based on the hereditary role of DNA. Moreover, not all mechanisms of EI attract the same attention, with most studies focused on DNA methylation, histone modification, RNA interference and amyloid prionization, but relatively few considering other mechanisms such as stable inhibition of plastid translation. Herein, we discuss all known and some hypothetical mechanisms that can underlie the stable inheritance of phenotypically distinct hereditary factors that lack differences in DNA sequence. These mechanisms include (i) regulation of transcription by DNA methylation, histone modifications, and transcription factors, (ii) RNA splicing, (iii)RNA-mediated post-transcriptional silencing, (iv) organellar translation, (v) protein processing by truncation,
(vi) post-translational chemical modifications, (vii) protein folding, and (viii) homologous and non-homologous protein
interactions. The breadth of this list suggests that any or almost any regulatory mechanism that participates in gene expression or gene-product functioning, under certain circumstances, may produce EI. Although the modes of EI are highly variable, in many epigenetic systems, stable allelic variants can be distinguished. Irrespective of their nature, all such alleles have an underlying similarity: each is a bimodular hereditary unit, whose features depend on (i) a certain epigenetic mark (epigenetic determinant) in the DNA sequence or its product, and (ii) the DNA sequence itself (DNA determinant; if this is absent, the epigenetic allele fails to perpetuate). Thus, stable allelic epigenetic inheritance (SAEI) does not contradict the hereditary role of DNA, but involves additional molecular mechanisms with no or almost no limitations to their variety.
Basic concepts & scope of recombinant DNA technology
Recombinant DNA technology involves combining DNA molecules from different sources and introducing them into host cells. Key developments include the discovery that DNA carries genetic information (Avery, 1944), determining DNA's structure (Watson and Crick, 1953), developing techniques to cut and join DNA (restriction enzymes and ligase, 1970s), and creating the first recombinant DNA molecules by combining bacterial plasmid and phage DNA (Cohen and Boyer, 1973). These advances laid the foundation for genetic engineering.
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Baryons at the edge of the x ray–brightest galaxy cluster
Baryons at the edge of the x ray–brightest galaxy cluster
COMPLETE GUIDE ON WRITING A RESEARCH PROPOSAL ON GENETICS IN THE 21ST CENTURY
COMPLETE GUIDE ON WRITING A RESEARCH PROPOSAL ON GENETICS IN THE 21ST CENTURY
Minor Planet Evidence for Water in the Rocky Debris of a Disrupted Extrasolar...
Minor Planet Evidence for Water in the Rocky Debris of a Disrupted Extrasolar...
Introduction of Animal Genetics & History of Genetics
Introduction of Animal Genetics & History of Genetics
Why Life is Difficult, and What We MIght Do About It
Why Life is Difficult, and What We MIght Do About It
Stat 1040, Recitation packet 11. A 1999 study claimed that.docx
Stat 1040, Recitation packet 11. A 1999 study claimed that.docx
The mechanisms of epigenetic inheritance: how diverse are they?
The mechanisms of epigenetic inheritance: how diverse are they?
Basic concepts & scope of recombinant DNA technology
Basic concepts & scope of recombinant DNA technology
Recently uploaded
Applied Science: Thermodynamics, Laws & Methodology.pdf
When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
Compexometric titration/Chelatorphy titration/chelating titration
Classification
Metal ion ion indicators
Masking and demasking reagents
Estimation of Magnisium sulphate
Calcium gluconate
Complexometric Titration/ chelatometry titration/chelating titration, introduction, Types-
1.Direct Titration
2.Back Titration
3.Replacement Titration
4.Indirect Titration
Masking agent, Demasking agents
formation of complex
comparition between masking and demasking agents,
Indicators/Metal ion indicators/ Metallochromic indicators/pM indicators,
Visual Technique,PM indicators (metallochromic), Indicators of pH, Redox Indicators
Instrumental Techniques-Photometry
Potentiometry
Miscellaneous methods.
Complex titration with EDTA.
The debris of the ‘last major merger’ is dynamically young
The Milky Way’s (MW) inner stellar halo contains an [Fe/H]-rich component with highly eccentric orbits, often referred to as the
‘last major merger.’ Hypotheses for the origin of this component include Gaia-Sausage/Enceladus (GSE), where the progenitor
collided with the MW proto-disc 8–11 Gyr ago, and the Virgo Radial Merger (VRM), where the progenitor collided with the
MW disc within the last 3 Gyr. These two scenarios make different predictions about observable structure in local phase space,
because the morphology of debris depends on how long it has had to phase mix. The recently identified phase-space folds in Gaia
DR3 have positive caustic velocities, making them fundamentally different than the phase-mixed chevrons found in simulations
at late times. Roughly 20 per cent of the stars in the prograde local stellar halo are associated with the observed caustics. Based
on a simple phase-mixing model, the observed number of caustics are consistent with a merger that occurred 1–2 Gyr ago.
We also compare the observed phase-space distribution to FIRE-2 Latte simulations of GSE-like mergers, using a quantitative
measurement of phase mixing (2D causticality). The observed local phase-space distribution best matches the simulated data
1–2 Gyr after collision, and certainly not later than 3 Gyr. This is further evidence that the progenitor of the ‘last major merger’
did not collide with the MW proto-disc at early times, as is thought for the GSE, but instead collided with the MW disc within
the last few Gyr, consistent with the body of work surrounding the VRM.
EWOCS-I: The catalog of X-ray sources in Westerlund 1 from the Extended Weste...
Context. With a mass exceeding several 104 M⊙ and a rich and dense population of massive stars, supermassive young star clusters
represent the most massive star-forming environment that is dominated by the feedback from massive stars and gravitational interactions
among stars.
Aims. In this paper we present the Extended Westerlund 1 and 2 Open Clusters Survey (EWOCS) project, which aims to investigate
the influence of the starburst environment on the formation of stars and planets, and on the evolution of both low and high mass stars.
The primary targets of this project are Westerlund 1 and 2, the closest supermassive star clusters to the Sun.
Methods. The project is based primarily on recent observations conducted with the Chandra and JWST observatories. Specifically,
the Chandra survey of Westerlund 1 consists of 36 new ACIS-I observations, nearly co-pointed, for a total exposure time of 1 Msec.
Additionally, we included 8 archival Chandra/ACIS-S observations. This paper presents the resulting catalog of X-ray sources within
and around Westerlund 1. Sources were detected by combining various existing methods, and photon extraction and source validation
were carried out using the ACIS-Extract software.
Results. The EWOCS X-ray catalog comprises 5963 validated sources out of the 9420 initially provided to ACIS-Extract, reaching a
photon flux threshold of approximately 2 × 10−8 photons cm−2
s
−1
. The X-ray sources exhibit a highly concentrated spatial distribution,
with 1075 sources located within the central 1 arcmin. We have successfully detected X-ray emissions from 126 out of the 166 known
massive stars of the cluster, and we have collected over 71 000 photons from the magnetar CXO J164710.20-455217.
Micronuclei test.M.sc.zoology.fisheries.
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Speaker: Diego Blas (IFAE/ICREA)
Title: Gravitational wave detection with orbital motion of Moon and artificial
Abstract:
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ESR spectroscopy in liquid food and beverages.pptx
With increasing population, people need to rely on packaged food stuffs. Packaging of food materials requires the preservation of food. There are various methods for the treatment of food to preserve them and irradiation treatment of food is one of them. It is the most common and the most harmless method for the food preservation as it does not alter the necessary micronutrients of food materials. Although irradiated food doesn’t cause any harm to the human health but still the quality assessment of food is required to provide consumers with necessary information about the food. ESR spectroscopy is the most sophisticated way to investigate the quality of the food and the free radicals induced during the processing of the food. ESR spin trapping technique is useful for the detection of highly unstable radicals in the food. The antioxidant capability of liquid food and beverages in mainly performed by spin trapping technique.
Direct Seeded Rice - Climate Smart Agriculture
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Randomised Optimisation Algorithms in DAPHNE
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Aleš Zamuda: Randomised Optimisation Algorithms in DAPHNE .
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https://ashpc.eu/
Katherine Romanak - Geologic CO2 Storage.pdf
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Thematic analysis in qualitative research is a time-consuming and systematic task, typically done using teams. Team members must ground their activities on common understandings of the major concepts underlying the thematic analysis, and define criteria for its development. However, conceptual misunderstandings, equivocations, and lack of adherence to criteria are challenges to the quality and speed of this process. Given the distributed and uncertain nature of this process, we wondered if the tasks in thematic analysis could be supported by readily available artificial intelligence chatbots. Our early efforts point to potential benefits: not just saving time in the coding process but better adherence to criteria and grounding, by increasing triangulation between humans and artificial intelligence. This tutorial will provide a description and demonstration of the process we followed, as two academic researchers, to develop a custom ChatGPT to assist with qualitative coding in the thematic data analysis process of immersive learning accounts in a survey of the academic literature: QUAL-E Immersive Learning Thematic Analysis Helper. In the hands-on time, participants will try out QUAL-E and develop their ideas for their own qualitative coding ChatGPT. Participants that have the paid ChatGPT Plus subscription can create a draft of their assistants. The organizers will provide course materials and slide deck that participants will be able to utilize to continue development of their custom GPT. The paid subscription to ChatGPT Plus is not required to participate in this workshop, just for trying out personal GPTs during it.
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Bio 104 Task 1_tagalog, H..doc
- 1. Name: Harold Tagalog Date: Jan. 29, 2023 Year & Sec: BSBIO- 2a BIOLOGY 104 GENETICS 2ND SEM. SY 2022-2023 TOPIC: Introductory LEARNING OBJECTIVE: to point out significant research findings [which couldz be tools and approaches/techniques] and scientists/researchers responsible for these contribution in enhancing our current understanding of the field of genetics TASK [1]: Research on the information as stated in the heading of each column and fill up the given matrix. Date [in chronological order] Seminal Findings or Breakthrough discoveries/Inventions [word or phrase only]; provide a picture if tools/devices Contributor/s or Maker or Researchers/Scientist/s Responsible [name/s and picture] What made this breakthrough a turning point for the field of genetics? [not to exceed 5 sentences]; 2 points each 1 1940 Discovering genetic transposition ("jumping genes"). Barbara McClintock Transposable elements (TEs), also known as "jumping genes," are DNA sequences that can move from one location on the genome to another. According to research, these sequences are essential for the species' growth, development, and evolution. A quarter of them, for example, are in charge of working on the genetic switches that turn on and off and can alter protein synthesis and gene action.
- 2. 2 1993 Develops genomic mismatch scanning. Patrick Brown A quick way to look for genes in families by comparing individual genomes. 3 1994 Tests gene alterations on vein grafts. Victor Dzau The new genes help make the veins resistant to clogging by plaque after they are grafted onto arteries in heart bypass surgery.
- 3. 4 1960 Cloned the second live mammal. Ryuzo Yanagimachi It is a turning point for the field of genetics, allowing the development of the human sperm penetration assay, which could aid in determining human fertility potential. 5 1950 Discovered the hereditary nature of Wilson disease. Alexander Gordon Bearn Which provided an important model for the identification, diagnosis, and treatment of other genetic diseases, served to bridge the gap between genetics and medicine that existed in the 1950s.
- 4. Due: January 30, 2023 @9:00 AM Submit to nadettejn@yahoo.com with the following file name: Bio 104 Task 1_tagalog, H.