This document contains summaries of three different crystal structures showing the HIV-1 envelope glycoprotein gp120 bound to CD4 and a neutralizing antibody. The structures include gp120 from different HIV-1 isolates complexed with human CD4 and antibody 17b, demonstrating the interaction between the viral protein, receptor, and immune system component at the atomic level across multiple representations.

1. HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b
Classification: Viral Protein / Immune System
Organism(s): Human immunodeficiency virus 1, Homo sapiens
Expression System: Homo sapiens, Escherichia coli
i) Wireframe:
ii) Sticks

2. iii) Spacefill
iv) Ball & Stick

3. v) Cartoon

4. HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING
HUMAN ANTIBODY
Classification: Viral protein/receptor/Immune system
Organism(s): Homo sapiens, Human immunodeficiency virus type 1 group M subtype B (isolate
HXB2)
Expression System: Mus musculus, Cricetulus griseus, Drosophila melanogaster
a) Wireframe
b) Sticks
c) Spacefill

5. d) Ball & Stick
e) Cartoons

7. Crystal structure of CD4M33, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2
gp120 envelope glycoprotein and anti-HIV-1 antibody 17b
Classification: Viral protein/Immune system
Organism(s): Human immunodeficiency virus type 1 group M subtype B (isolate YU-2)
Expression System: Mus musculus, Drosophila melanogaster
i) Wireframe
ii) Sticks
iii) Spacefill

8. iv) Ball & Sticks

9. v) Cartoon