Doppler ultrasound uses the Doppler effect to measure the direction and speed of blood cells as they move through vessels. It works by detecting changes in the pitch of reflected sound waves caused by moving blood cells. A computer collects and processes the sounds and creates color images representing blood flow. Doppler ultrasound can detect abnormalities, measure blood flow, screen for blockages, and evaluate vessels. It is a noninvasive way to obtain information about blood circulation.
1) Doppler ultrasound works by detecting changes in frequency of reflected ultrasound waves caused by moving red blood cells. This frequency change is known as the Doppler shift.
2) The Doppler shift is directly proportional to the velocity of blood flow, the angle of insonation, and the transmitted ultrasound frequency. It is used to determine blood velocity despite usually not knowing the exact insonation angle.
3) Power Doppler is more angle independent and sensitive to flow compared to standard color Doppler as it displays the power of Doppler shifts rather than mean frequency or velocity.
Doppler ultrasound uses the Doppler effect to measure blood flow velocity. It works by transmitting ultrasound pulses that reflect off moving red blood cells, with the frequency of the returning echoes shifted based on the velocity of flow. Continuous wave Doppler lacks depth resolution while pulsed wave Doppler can determine depth but has limitations on maximum detectable velocity. Duplex scanning combines B-mode imaging with pulsed Doppler to allow visualization of anatomy and measurement of flow velocities within vessels. Spectral Doppler analysis displays the distribution of velocities over time as a spectrum, providing quantitative flow information. Proper Doppler technique requires optimizing factors like transducer frequency, Doppler angle, and sample volume placement.
Doppler ultrasound utilizes the Doppler effect to detect moving objects like blood cells. It works by transmitting ultrasound pulses and detecting shifts in the frequency of echoes from moving reflectors. There are different Doppler modes including continuous wave, pulsed wave, color Doppler, and spectral Doppler. Optimization involves adjusting settings like gain, filter, sample volume size, and velocity scale. Common artifacts include aliasing, blooming, flash, and mirror artifacts. Doppler ultrasound provides both qualitative and quantitative assessment of blood flow.
Doppler ultrasound utilizes the Doppler effect to detect moving objects like blood flow inside the body. It works by transmitting ultrasound pulses into the body and detecting the change in frequency (Doppler shift) of echoes reflected from moving structures like blood cells. There are different Doppler ultrasound modes - continuous wave measures presence and direction of flow while pulsed wave provides depth information. Spectral Doppler displays flow information as a waveform while color Doppler images flow in color overlaid on anatomy. Optimization involves adjusting settings like Doppler angle, sample volume size, and velocity scale to improve sensitivity and accuracy.
When a sound source and the reflector are moving toward each other, the sound waves are spaced closer together and reach the receiver at a higher frequency than they were originally emitted “
Doppler ultrasound uses the Doppler effect to measure the direction and speed of blood cells as they move through vessels. It works by detecting changes in the pitch of reflected sound waves caused by moving blood cells. A computer collects and processes the sounds and creates color images representing blood flow. Doppler ultrasound can detect abnormalities, measure blood flow, screen for blockages, and evaluate vessels. It is a noninvasive way to obtain information about blood circulation.
1) Doppler ultrasound works by detecting changes in frequency of reflected ultrasound waves caused by moving red blood cells. This frequency change is known as the Doppler shift.
2) The Doppler shift is directly proportional to the velocity of blood flow, the angle of insonation, and the transmitted ultrasound frequency. It is used to determine blood velocity despite usually not knowing the exact insonation angle.
3) Power Doppler is more angle independent and sensitive to flow compared to standard color Doppler as it displays the power of Doppler shifts rather than mean frequency or velocity.
Doppler ultrasound uses the Doppler effect to measure blood flow velocity. It works by transmitting ultrasound pulses that reflect off moving red blood cells, with the frequency of the returning echoes shifted based on the velocity of flow. Continuous wave Doppler lacks depth resolution while pulsed wave Doppler can determine depth but has limitations on maximum detectable velocity. Duplex scanning combines B-mode imaging with pulsed Doppler to allow visualization of anatomy and measurement of flow velocities within vessels. Spectral Doppler analysis displays the distribution of velocities over time as a spectrum, providing quantitative flow information. Proper Doppler technique requires optimizing factors like transducer frequency, Doppler angle, and sample volume placement.
Doppler ultrasound utilizes the Doppler effect to detect moving objects like blood cells. It works by transmitting ultrasound pulses and detecting shifts in the frequency of echoes from moving reflectors. There are different Doppler modes including continuous wave, pulsed wave, color Doppler, and spectral Doppler. Optimization involves adjusting settings like gain, filter, sample volume size, and velocity scale. Common artifacts include aliasing, blooming, flash, and mirror artifacts. Doppler ultrasound provides both qualitative and quantitative assessment of blood flow.
Doppler ultrasound utilizes the Doppler effect to detect moving objects like blood flow inside the body. It works by transmitting ultrasound pulses into the body and detecting the change in frequency (Doppler shift) of echoes reflected from moving structures like blood cells. There are different Doppler ultrasound modes - continuous wave measures presence and direction of flow while pulsed wave provides depth information. Spectral Doppler displays flow information as a waveform while color Doppler images flow in color overlaid on anatomy. Optimization involves adjusting settings like Doppler angle, sample volume size, and velocity scale to improve sensitivity and accuracy.
When a sound source and the reflector are moving toward each other, the sound waves are spaced closer together and reach the receiver at a higher frequency than they were originally emitted “
This document provides an introduction to ultrasound physics, including how sonographic imaging works. It explains that ultrasound uses sound waves above the range of human hearing to produce images. Sonography works using a pulse-echo technique where an ultrasound transducer sends out pulses and receives echoes to create scan lines that compose images. Images can be displayed in linear or sector formats depending on the pulse direction. Doppler ultrasound detects the frequency shift of echoes from moving objects like blood cells to determine blood flow direction and velocity. Doppler information can be presented audibly, through color doppler imaging, or with spectral Doppler graphs.
This concepts of Doppler physics contents are introduction, history, on which principle it works, applications of this physics Doppler angle types of flow types of Doppler advantages disadvantages and summary
Doppler echocardiography uses the Doppler effect to analyze the velocity and direction of blood flow. There are several Doppler modalities used in cardiac evaluation including continuous wave Doppler, pulsed wave Doppler, and color flow Doppler. Continuous wave Doppler measures very high velocities, pulsed wave Doppler samples local low velocities, and color flow Doppler visually displays velocities using color scales. The Nyquist limit defines the maximum detectable velocity and avoiding aliasing. Tissue Doppler also evaluates myocardial velocities. The Bernoulli equation relates velocity and pressure gradients which allows Doppler to estimate valve pressures.
Doppler echocardiography uses the Doppler effect to analyze the velocity and direction of blood flow. There are several Doppler modalities used in cardiac evaluation including continuous wave Doppler, pulsed wave Doppler, and color flow Doppler. Continuous wave Doppler measures very high velocities, pulsed wave Doppler samples local low velocities, and color flow Doppler visually displays velocities using color scales. The Nyquist limit defines the maximum detectable velocity and avoiding aliasing. Tissue Doppler also evaluates myocardial velocities. The Bernoulli equation relates velocity and pressure gradients which allows Doppler to estimate valve pressures.
Color Doppler ultrasound uses the Doppler effect to detect moving structures like blood flow. It works by transmitting ultrasound pulses and detecting shifts in frequency between transmitted and echoed pulses based on the movement of reflectors like blood cells. There are different Doppler modes including continuous wave, pulsed wave, color Doppler, and spectral Doppler which analyze blood flow in various ways. Optimization of color Doppler examination involves adjusting settings like transducer frequency, Doppler angle, sample volume, and velocity scale to accurately depict flow.
This document discusses the role of color Doppler ultrasound in antepartum fetal surveillance. It begins by outlining the purposes of fetal surveillance, which include reducing fetal death and optimizing delivery timing. It then discusses various maternal and fetal conditions that require increased surveillance due to risks of chronic hypoxia. The document covers different methods of antepartum surveillance and provides detailed explanations of Doppler ultrasound principles, techniques like uterine and umbilical artery Doppler, and how abnormal Doppler readings can predict complications like fetal growth restriction.
Doppler ultrasound uses the Doppler effect to measure the velocity of moving objects like blood cells. It works by detecting the change in frequency (known as the Doppler shift) between the transmitted ultrasound pulse and its echo off moving objects. The Doppler shift equation relates the shift frequency to factors like ultrasound frequency, velocity of the moving object, and the angle between the ultrasound beam and object velocity. Doppler ultrasound is useful for clinical applications like evaluating blood flow and detecting abnormalities.
Doppler ultrasound uses high frequency sound waves to visualize blood vessels. It is a non-invasive technique to test for conditions like deep vein thrombosis. The document discusses the Doppler effect, which is a change in observed frequency of a wave caused by relative motion between the source and observer. It defines key terms like frequency and wavelength. It also describes different Doppler ultrasound techniques like continuous wave and color Doppler, and discusses applications in assessing blood flow velocity and direction in vessels.
Exploring Doppler Effect Physics: Frequency Shifts in Sound and Light Waves D...DrRizwanAhmed4
The Doppler effect, or Doppler shift, describes the change in frequency or wavelength of a wave in relation to an observer moving relative to the wave source. It is commonly observed in sound waves but also applies to electromagnetic waves such as light. When the source and the observer are moving closer together, the observed frequency increases (blue shift in light), and when they are moving apart, the observed frequency decreases (red shift in light).
This slide contain application of ultrasound and biological effects of ultrasound , ppt contains many GIF files and notes , which may not be accessible here ,,
This document provides an overview of Doppler physics and ultrasound techniques used to evaluate blood flow velocity. It discusses the Doppler effect, continuous wave and pulsed Doppler, color flow imaging, power Doppler, and spectral Doppler analysis. Key points covered include how Doppler shift relates to velocity, the Nyquist limit, factors that affect the Doppler signal, and common Doppler artifacts. The summary evaluates blood flow using ultrasound Doppler modalities.
1) There are several types of Doppler ultrasound used to evaluate blood flow, including color Doppler imaging (CDI), power Doppler, spectral Doppler, duplex Doppler, and continuous wave Doppler.
2) CDI uses color coding to depict blood flow direction and velocity, power Doppler provides greater detail of blood flow, spectral Doppler yields graphical representations of flow velocity over time, duplex Doppler combines B-mode and Doppler imaging, and continuous wave Doppler utilizes dedicated transmit and receive elements without pulses.
3) The optimal Doppler technique depends on the application and aims to accurately measure blood flow velocities while avoiding artifacts from incorrect gain settings or angle dependencies.
Doppler ultrasound utilizes the Doppler effect to detect moving structures in the body. It works by transmitting ultrasound pulses and detecting changes in frequency between transmitted and received signals based on the movement of reflective structures like blood cells. There are different Doppler modes including continuous wave, pulsed wave, color flow, and spectral Doppler which provide quantitative or qualitative assessments of flow. Optimization of Doppler techniques and understanding artifacts can improve diagnostic accuracy. Recent innovations continue enhancing Doppler ultrasound capabilities.
1. Aliasing occurs when the Doppler shift is higher than half the pulse repetition frequency, causing signals to become indistinguishable and display with the wrong color or velocity. It can be corrected by increasing the pulse repetition frequency or adjusting the baseline.
2. Mirror artifacts occur when the ultrasound beam reflects off a structure like bone or diaphragm before returning to the transducer, creating a duplicate image. Changing the angle of insonation can help avoid it.
3. Motion artifacts appear as random color flashes caused by movement of the patient, transducer, or tissue during imaging. They can be minimized by comfortable patient positioning and a stable scanning arm.
Doppler ultrasound uses the Doppler effect to measure the velocity of moving objects like blood cells. It works by transmitting ultrasound pulses and detecting slight differences in the echoes from moving scatterers compared to stationary tissue. These differences are measured as a Doppler frequency shift, which can be used to calculate velocity if the angle between the ultrasound beam and flow direction is known. Doppler ultrasound provides both spectral Doppler displays of velocity over time at a single point, as well as color flow imaging, which produces color-coded maps of flow direction and velocity superimposed on B-mode images. Factors like velocity, ultrasound frequency, beam-flow angle, and imaging mode affect the quality of Doppler ultrasound images.
This document discusses Doppler ultrasound principles including the Doppler effect, spectral Doppler parameters, and optimizing Doppler measurements. The key points are:
1) The Doppler effect is the change in frequency/pitch of a wave due to relative motion between the source and observer. This principle allows Doppler ultrasound to detect the direction and velocity of blood flow.
2) Important spectral Doppler parameters that affect measurements include the baseline, Doppler angle, and velocity scale. The baseline and velocity scale must be optimized to prevent aliasing, while the Doppler angle should be corrected to compensate for inaccuracies introduced by non-parallel ultrasound beams.
3) Correctly adjusting these spectral Doppler parameters is essential for obtaining accurate blood flow velocity measurements and meaningful Doppler
The Doppler effect refers to the change in frequency of a wave as the source and observer move relative to each other. The document discusses the history of the Doppler effect and its discovery by Doppler in 1842. It defines key terms like frequency and wavelength and presents the Doppler effect equation. Examples are given of how the equation applies to moving sources and observers. Real-life applications like monitoring blood flow and fetal heartbeats using Doppler are also mentioned.
Normal doppler spectral pattern of abdominal and limb vessels finalNipun Gupta
This document provides information on normal Doppler patterns of abdominal vessels. It begins by covering Doppler physics principles. It then discusses normal Doppler flow patterns seen in the abdominal aorta, ductus venosus, celiac artery, superior mesenteric artery, and mesenteric arteries. For each vessel, it describes anatomy, imaging recommendations, and typical Doppler waveform patterns. The document serves as an educational guide for residents to learn how to properly evaluate and interpret Doppler ultrasound of the abdominal vasculature.
This document provides an introduction to ultrasound physics, including how sonographic imaging works. It explains that ultrasound uses sound waves above the range of human hearing to produce images. Sonography works using a pulse-echo technique where an ultrasound transducer sends out pulses and receives echoes to create scan lines that compose images. Images can be displayed in linear or sector formats depending on the pulse direction. Doppler ultrasound detects the frequency shift of echoes from moving objects like blood cells to determine blood flow direction and velocity. Doppler information can be presented audibly, through color doppler imaging, or with spectral Doppler graphs.
This concepts of Doppler physics contents are introduction, history, on which principle it works, applications of this physics Doppler angle types of flow types of Doppler advantages disadvantages and summary
Doppler echocardiography uses the Doppler effect to analyze the velocity and direction of blood flow. There are several Doppler modalities used in cardiac evaluation including continuous wave Doppler, pulsed wave Doppler, and color flow Doppler. Continuous wave Doppler measures very high velocities, pulsed wave Doppler samples local low velocities, and color flow Doppler visually displays velocities using color scales. The Nyquist limit defines the maximum detectable velocity and avoiding aliasing. Tissue Doppler also evaluates myocardial velocities. The Bernoulli equation relates velocity and pressure gradients which allows Doppler to estimate valve pressures.
Doppler echocardiography uses the Doppler effect to analyze the velocity and direction of blood flow. There are several Doppler modalities used in cardiac evaluation including continuous wave Doppler, pulsed wave Doppler, and color flow Doppler. Continuous wave Doppler measures very high velocities, pulsed wave Doppler samples local low velocities, and color flow Doppler visually displays velocities using color scales. The Nyquist limit defines the maximum detectable velocity and avoiding aliasing. Tissue Doppler also evaluates myocardial velocities. The Bernoulli equation relates velocity and pressure gradients which allows Doppler to estimate valve pressures.
Color Doppler ultrasound uses the Doppler effect to detect moving structures like blood flow. It works by transmitting ultrasound pulses and detecting shifts in frequency between transmitted and echoed pulses based on the movement of reflectors like blood cells. There are different Doppler modes including continuous wave, pulsed wave, color Doppler, and spectral Doppler which analyze blood flow in various ways. Optimization of color Doppler examination involves adjusting settings like transducer frequency, Doppler angle, sample volume, and velocity scale to accurately depict flow.
This document discusses the role of color Doppler ultrasound in antepartum fetal surveillance. It begins by outlining the purposes of fetal surveillance, which include reducing fetal death and optimizing delivery timing. It then discusses various maternal and fetal conditions that require increased surveillance due to risks of chronic hypoxia. The document covers different methods of antepartum surveillance and provides detailed explanations of Doppler ultrasound principles, techniques like uterine and umbilical artery Doppler, and how abnormal Doppler readings can predict complications like fetal growth restriction.
Doppler ultrasound uses the Doppler effect to measure the velocity of moving objects like blood cells. It works by detecting the change in frequency (known as the Doppler shift) between the transmitted ultrasound pulse and its echo off moving objects. The Doppler shift equation relates the shift frequency to factors like ultrasound frequency, velocity of the moving object, and the angle between the ultrasound beam and object velocity. Doppler ultrasound is useful for clinical applications like evaluating blood flow and detecting abnormalities.
Doppler ultrasound uses high frequency sound waves to visualize blood vessels. It is a non-invasive technique to test for conditions like deep vein thrombosis. The document discusses the Doppler effect, which is a change in observed frequency of a wave caused by relative motion between the source and observer. It defines key terms like frequency and wavelength. It also describes different Doppler ultrasound techniques like continuous wave and color Doppler, and discusses applications in assessing blood flow velocity and direction in vessels.
Exploring Doppler Effect Physics: Frequency Shifts in Sound and Light Waves D...DrRizwanAhmed4
The Doppler effect, or Doppler shift, describes the change in frequency or wavelength of a wave in relation to an observer moving relative to the wave source. It is commonly observed in sound waves but also applies to electromagnetic waves such as light. When the source and the observer are moving closer together, the observed frequency increases (blue shift in light), and when they are moving apart, the observed frequency decreases (red shift in light).
This slide contain application of ultrasound and biological effects of ultrasound , ppt contains many GIF files and notes , which may not be accessible here ,,
This document provides an overview of Doppler physics and ultrasound techniques used to evaluate blood flow velocity. It discusses the Doppler effect, continuous wave and pulsed Doppler, color flow imaging, power Doppler, and spectral Doppler analysis. Key points covered include how Doppler shift relates to velocity, the Nyquist limit, factors that affect the Doppler signal, and common Doppler artifacts. The summary evaluates blood flow using ultrasound Doppler modalities.
1) There are several types of Doppler ultrasound used to evaluate blood flow, including color Doppler imaging (CDI), power Doppler, spectral Doppler, duplex Doppler, and continuous wave Doppler.
2) CDI uses color coding to depict blood flow direction and velocity, power Doppler provides greater detail of blood flow, spectral Doppler yields graphical representations of flow velocity over time, duplex Doppler combines B-mode and Doppler imaging, and continuous wave Doppler utilizes dedicated transmit and receive elements without pulses.
3) The optimal Doppler technique depends on the application and aims to accurately measure blood flow velocities while avoiding artifacts from incorrect gain settings or angle dependencies.
Doppler ultrasound utilizes the Doppler effect to detect moving structures in the body. It works by transmitting ultrasound pulses and detecting changes in frequency between transmitted and received signals based on the movement of reflective structures like blood cells. There are different Doppler modes including continuous wave, pulsed wave, color flow, and spectral Doppler which provide quantitative or qualitative assessments of flow. Optimization of Doppler techniques and understanding artifacts can improve diagnostic accuracy. Recent innovations continue enhancing Doppler ultrasound capabilities.
1. Aliasing occurs when the Doppler shift is higher than half the pulse repetition frequency, causing signals to become indistinguishable and display with the wrong color or velocity. It can be corrected by increasing the pulse repetition frequency or adjusting the baseline.
2. Mirror artifacts occur when the ultrasound beam reflects off a structure like bone or diaphragm before returning to the transducer, creating a duplicate image. Changing the angle of insonation can help avoid it.
3. Motion artifacts appear as random color flashes caused by movement of the patient, transducer, or tissue during imaging. They can be minimized by comfortable patient positioning and a stable scanning arm.
Doppler ultrasound uses the Doppler effect to measure the velocity of moving objects like blood cells. It works by transmitting ultrasound pulses and detecting slight differences in the echoes from moving scatterers compared to stationary tissue. These differences are measured as a Doppler frequency shift, which can be used to calculate velocity if the angle between the ultrasound beam and flow direction is known. Doppler ultrasound provides both spectral Doppler displays of velocity over time at a single point, as well as color flow imaging, which produces color-coded maps of flow direction and velocity superimposed on B-mode images. Factors like velocity, ultrasound frequency, beam-flow angle, and imaging mode affect the quality of Doppler ultrasound images.
This document discusses Doppler ultrasound principles including the Doppler effect, spectral Doppler parameters, and optimizing Doppler measurements. The key points are:
1) The Doppler effect is the change in frequency/pitch of a wave due to relative motion between the source and observer. This principle allows Doppler ultrasound to detect the direction and velocity of blood flow.
2) Important spectral Doppler parameters that affect measurements include the baseline, Doppler angle, and velocity scale. The baseline and velocity scale must be optimized to prevent aliasing, while the Doppler angle should be corrected to compensate for inaccuracies introduced by non-parallel ultrasound beams.
3) Correctly adjusting these spectral Doppler parameters is essential for obtaining accurate blood flow velocity measurements and meaningful Doppler
The Doppler effect refers to the change in frequency of a wave as the source and observer move relative to each other. The document discusses the history of the Doppler effect and its discovery by Doppler in 1842. It defines key terms like frequency and wavelength and presents the Doppler effect equation. Examples are given of how the equation applies to moving sources and observers. Real-life applications like monitoring blood flow and fetal heartbeats using Doppler are also mentioned.
Normal doppler spectral pattern of abdominal and limb vessels finalNipun Gupta
This document provides information on normal Doppler patterns of abdominal vessels. It begins by covering Doppler physics principles. It then discusses normal Doppler flow patterns seen in the abdominal aorta, ductus venosus, celiac artery, superior mesenteric artery, and mesenteric arteries. For each vessel, it describes anatomy, imaging recommendations, and typical Doppler waveform patterns. The document serves as an educational guide for residents to learn how to properly evaluate and interpret Doppler ultrasound of the abdominal vasculature.
Know the difference between Endodontics and Orthodontics.Gokuldas Hospital
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
3. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
1) General Principles
2) Color Doppler Specific Parameters
3) Power Doppler Imaging
4) Spectral Doppler Specific Parameters
5) Normal flow in Arteries and Veins
5. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• Christian Andreas Doppler was an Austrian
mathematician; he first observed that
certain properties of light emitted from stars
depend upon the relative motion of the
observer and the wave source.
• Colored appearance of some stars as due to
their motion relative to the earth, the blue
ones moving toward earth and the red ones
moving away.
• He theorized that sound waves from a moving
source would be compressed or expanded, or
that the frequency would change.
• This theory wasn't tested until 1845.
• B. Ballot 1845 confirmed Doppler’s with horn
players on a train .
• Later, a scientist named Fizeau generalized
Doppler's work by applying his theory not
only to sound but also to light.
7. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
OBSERVER 2
Long wavelength
Low frequency
OBSERVER 1
Small wavelength
High frequency
8. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
DOPPLER FREQUENCY SHIFT :–
Higher returned frequency if RBCs are moving
towards the Transducer and lower if the cells are
moving away from transducer
9. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• Understanding the Doppler equation will enable you to quickly
identify the factors that affect the Doppler shift scenario.
• Fd is Doppler shifted frequency (what we measure).
• V is velocity of RBC (what we want to know).
• Ft is transducer (transmitted) frequency .
• Cos ϴ is cosine of angle between direction of flow and ultrasound beam.
• C is velocity of sound in the body tissues.
Fd = 2 Ft V (cosine Ф)
C
10. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
THE DOPPLER SHIFT FREQUENCY:
• The Doppler shift frequency is the difference
between the received frequency and
transmitted frequency.
• It is directly proportional to transducer
frequency.
12. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
Goals of Doppler
• Detection of flow in vessel
• Detection of flow direction
• Detection of flow Type:
» Aterial or venous
» Normal or abnormal
• Measurement of the flow velocity
13. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
Types of Doppler
I. Color Doppler.
II. Power Doppler
III.Pulsed Doppler.
IV.Continuous wave Doppler.
14. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
All Doppler Should be
performed with
I. Gray scale Ultrasound
II. Color Doppler
III.Power Doppler
IV.Pulsed Doppler
41. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• To perform good Pulsed Doppler you must be
able to understand the spectral display.
• It is a graphical representation of analyzed
Doppler shifts.
• It displays three components of the Doppler
shift as they occur over time: the direction of
the shift, the magnitude of the shift, and the
amplitude of the shift.
43. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• Shift Direction: The baseline on the spectral
display separates the positive from negative
shifts. Positive shifts are displayed on one
side; negative shifts are displayed on the
other.
44. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• Shift Magnitude: This is the size of the shift. Recall the
factors on the right side of the Doppler equation. These
are the factors that affect the magnitude of the
Doppler shift. The two primary factors that affect the
magnitude of the Doppler shift are blood velocity and
Doppler angle.
• The magnitude of the Doppler shift is displayed on the
vertical (Y) axis of the spectral display. Higher shifts are
displayed farther from the baseline, lower shifts are
displayed closer to the baseline.
• The magnitude of the Doppler shift is represented on
the vertical.
46. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• Shift Amplitude: This is the strength of the shift. Is it a
strong signal or a weak signal? The factors that affect the
amplitude of the signal are the same as those that affect
the amplitude of any echo: output power, attenuation,
acoustic impedance mismatch, type of reflector. However,
since the signal is coming from within a small sample
volume within moving blood, the primary factor that
changes the amplitude of the signal is the number of red
blood cells flowing through the sample volume. The more
blood, the stronger the signal. The amplitude of the shift is
represented by the brightness of the display. Strong shifts
are displayed with bright pixels, weaker shifts are displayed
with darker pixels.
48. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• Time: Time is displayed on the horizontal axis.
A typical display shows 3-4 seconds along the
X axis.
• Shift Magnitude: The magnitude of the
Doppler shift is displayed on the vertical axis.
• Shift Amplitude: The amplitude (strength) of
the Doppler shifted echoes is represented by
the brightness of the display (Z axis).
52. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• Baseline: The horizontal baseline separates
the positive and negative channels.
• Channels: Positive shifts are displayed in the
positive channel. Negative shifts in the
negative channel. The channels are usually,
but not always, indicated by a “positive” and
“negative” sign.
53. THE DOPPLER PRRINCIPLE AND INSTRUMENTATION
• Nyquist Limit: The
Nyquist is the
upper limit of each
channel.
• The Nyquist can be
changed by
changing the
scale.