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International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume 7 Issue 6, November-December 2023 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470
@ IJTSRD | Unique Paper ID – IJTSRD60101 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 37
Ayurvedic Management of Vipadika - A Case Study
Dr. Subhashree Singha1, Prof. (Dr.) Pragya. P. Mallik2, Dr. Sonalika Jena3, Dr. Santilata Sahoo4
1
MD Scholar, PG Department of Kayachikitsa, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India
2
HOD, PG Department of Kayachikitsa, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India
3, 4
Reader, PG Department of Kayachikitsa, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India
ABSTRACT
Ayurveda is World’s oldest holistic healing system. According to
Ayurveda Kustha Roga (Skin disorders) occurs due to an imbalance
in body’s Tridosha- Vata, Pitta, Kapha. Vipadika is a Vata – Kapha
predominance type of Kshudra Kustha. This can be co-related with
Palmo – plantar Psoriasis in modern medical science. Palmo – Plantar
Psoriasis is a relatively unknown variant of Psoriasis that affects
Palm and soles of individuals of all ages. It represent 3-4% of all
Psoriasis cases and is the 2nd
most common type of Psoriasis
followed by Chronic Plaque Psoriasis. This is a variant of Psoriasis
which is resistant to many forms of treatment.
The present case study is a case of 52 years patient diagnosed as
Vipadika (Palmo-Plantar Psoriasis) based on its clinical sign and
symptoms. In this study a treatment protocol containg Six
formulations 1.Gandhaka Rasayana, 2.Rasabhra Guggulu, 3.
Avipattikara Choorna, 4. Mahamanjisthadi Kwatha, 5. Karanja taila
with Haridra, 6. Satadhauta Ghrita administered for 1 month.
KEYWORDS: Kustha, Vipadika, Kusthaghna, Kandughna, Deepana-
pachan, Varnaropana, Vedanasthapana, Sothahara
How to cite this paper: Dr. Subhashree
Singha | Prof. (Dr.) Pragya. P. Mallik |
Dr. Sonalika Jena | Dr. Santilata Sahoo
"Ayurvedic Management of Vipadika -
A Case Study" Published in
International
Journal of Trend in
Scientific Research
and Development
(ijtsrd), ISSN:
2456-6470,
Volume-7 | Issue-6,
December 2023,
pp.37-39, URL:
www.ijtsrd.com/papers/ijtsrd60101.pdf
Copyright © 2023 by author (s) and
International Journal of Trend in
Scientific Research and Development
Journal. This is an
Open Access article
distributed under the
terms of the Creative Commons
Attribution License (CC BY 4.0)
(http://creativecommons.org/licenses/by/4.0)
INTRODUCTION
Healthy Skin is a reflection of overall health. Twak
(Skin) is the largest organ of body. There is healthy
skin to make an individual more confident in both
mentally and physically. Now a days Twak vikara is
arising due to Urbanization and Stressful life
style.The disease entity named Vipadika is described
in Brihatrayi . There are two types of Kustha have
been described in Ayurvedic classics that is 7 Maha
kustha and 11 Kshudra kustha. Vipadika is a type of
Kshudra kustha1
with Vata- Kapha dosha
involvement and is characterized by “Pani-Pada
Sphutana and Teevra Vedana”2
by Acharya Charak.
Acharya Vagbhata has stated that same features as
described by Acharya Charak but mentioned one
feature i.e. red patches over Palms and Soles3
.
Vipadika can be co-related with Palmo-Plantar
Psoriasis which is a Chronic, inflammatory disease
characterized by red, itchy, scaly patches over the
Palms and Soles4
. There are multiple painful cracks
and bleeding also present.
In modern science, it is commonly treated with
corticosteroids, topical therapies, vitamins, Immune
modulators. But commonly this disease relapses again
and again. Through Ayurvedic treatment it can be
managed without re-occurrence of the disease.
CASE STUDY
Center of study- OPD of Kayachikitsa Department,
Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha,
India.
Case report – A male patient of age 52 years came to
OPD of Kayachikitsa Department, GAM, Puri with
chief complaints- itching sensation, cracks and severe
pain on both soles since 3 years.
History of Present Illness- Complaints started with
itching and slight scaling on both soles before 3 years.
After few months he suffered from slight bleeding
with pain on both soles. After few years, he
developed cracks, severe pain & more itching
sensation on both soles. He was taking different type
of Modern medication, but it provided him only
temporary relief.
IJTSRD60101
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD60101 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 38
Aggravating factor- Un hygienic Work Place, non-
veg diet, over eating, junk food, hot and spicy food.
History of Past Illness- There was no relevant past
history.
Family history- No member of family had such
illness.
Personal history-
 Diet Mixed diet
 Bowel Irregular
 Micturition Normal
 Sleep Disturbed
 Addiction Tobacco
On examination-
 BP 130 / 86 mmHg
 Pulse 78 / min
 Weight 74 kg
Systemic Examination-
 RS-AEBE, bilateral clear
 CVS- S1S2 normal
 CNS- Conscious, Oriented
Nidana Panchaka
 Nidana
• Non veg diet, Sea food
• Tea (4-5 times), White flour product, Deep fried
food 5 times a day
• Atichintana (Stress full mind)
• Divaswapna (Day sleep)
 Poorva Roopa
• Kandu
 Roopa
• Cracking of both soles, scaling, itching, bleeding
and pain on both soles
 Upashaya
• After treatment
 Samprapti
• Hetu sevana
• Vata – Kapha Pradhana Tridosha
• Lasika (Ambu), Twak, Rakta, Mamsa
• Lakshanotapatti
Samprapti Ghataka
 Dosha – Vata – Kapha Pradhana Tridosha
 Dushya – Lasika, Twak, Rakta, Mamsa
 Srotos – Rasa, Rakta, Mamsa, Sweda vaha Srotos
 Sroto dusti – Sanga, Vimarga gamana
 Agni- Mandagni
 Vyadhi Marga – Bahya
TREATMENT PROTOCOL
Name of the Drug Dose Duration
Gandhaka Rasayana 125 mg Twice a day with luke warm water, After food
Rasabhra Guggulu 500 mg Twice a day with luke warm water, After food
Avipattikara Choorna 5 gm Twice a day with luke warm water, before food
Mahamanjisthadi Kwatha 15 ml Twice a day with equal amount of water After meal
Karanja taila + Haridra Sufficient quantity Externally
Satadhauta ghrta Sufficient quantity Externally
Advice – Patient was advised to take care of his soles.
 Maintain Proper hygiene
 Always wear soft sleeper
 Clean with luke warm water
Fig. 1- Before Treatment Fig. 2- After Treatment Fig. 3- After Treatment
RESULT
After 1month of Proper medication the symptoms like cracking of both soles, itching, scaling, bleeding from
cracked region reduced. The patient was advised for follow up and avoiding fried food items, non-vegetarian
food & sea food.
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD60101 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 39
DISCUSSION
Gandhaka Rasayana5, 6
- It is useful in various skin
diseases such as Eczema, Psoriasis, several types of
wounds. It is very much effective towards curing
abscesses and Chronic non healing wounds.
Rasabhra Guggulu7
- It acts as deepaneeya,
tridoshahara, srotoshodhaka, raktadustihara, as well
as good immune modulator. Its ingredients like
Abhrak bhasma mainly used in kaphavata disorder,
loha bhasma has lekhana guna which eliminates mala
rupi kapha and drugs like jaiphala, Triphala helps to
removal of vitiated doshas.
Avipattikara churna8
- It contains sunthi, pippali,
maricha, haritaki, vibhitaki, amalaki, ela, tejapatra,
nagarmotha, vidlavana, vayavidanga, all in equal
parts with 11 parts of lavanga, 44 parts of sita. It
helps in Proper Deepana and Pachana, in
agnimandya, Triphala is a best anti oxidant, Vidanga
have properties like anti microbial activities.
Mahamanjisthadi Kwatha9
- It acts as blood purifier,
antioxidant with healing properties. It is used in the
treatment of Skin diseases due to its sothahara,
Varnaropaka, Varnya properties
Karanja taila10, 11
- Due to its Tikta, Katu rasa and
Usna virya, it is Vataghna and Kaphaghna . It is
effectively used because of its Kandughna,
Kusthaghna, Jantughna, Varnaropana and
Vedanasthapana properties.
Haridra12
- It contains katu, Tikta rasa which acts
against kaphadosha. Acharya charak has mentioned
haridra in Kusthaghna, Vishaghna, lekhaniya
mahakashya.
Satadhauta ghrta13
-Due to its Antiseptic, Antibacterial
and Soothing properties it is indicated in various skin
disease such as Visarpa, Kustha, Kandu etc.
CONCLUSION
The case study could be conclude that Ayurvedic
management seems to very effective and curative
over Vipadika like skin disease. From the above case,
it can be said that Palmo-plantar Psoriasis can be
successfully managed through Ayurvedic treatment.
REFERENCES
[1] Agnivesha, Charak, Dridhabala, Charak
Samhita ‘Vidyotini’ Hindi Commentary by
Pt.Kasinatha Sastri, Dr.Gorakhanath
Chaturvedi, Part 2 Chapter 7 Ch.chi Verse 13
pg no-250 by Chaukhambha Bharati Academy,
Varanasi, (Reprinted.). 2016.
[2] Agnivesha, Charak, Dridhabala, Charak
Samhita ‘Vidyotini’ Hindi Commentary by
Pt.Kasinatha Sastri, Dr.Gorakhanath
Chaturvedi, Part 2 Chapter 7 Ch.chi Verse 21-
26 pg no-252 by Chaukhambha Bharati
Academy, Varanasi, (Reprinted.). 2016.
[3] Vaghbhata, Astanga Hridyam of by Kaviraj
Atrideva Gupta, with ‘Vidyotini’ Hindi
Commentary, edited by Vaidya Yadunandana
Upadhhyaya, Chapter 14 verse 22-23 pg no-371
Chaukhambha Prakashan, Varanasi, (Reprint
ed.). 2018.
[4] Klaus Wolff, Lowell A Goldsmith, Stephen I.
Katz, Barbara A. Gilchrest, Amy Paller, David
J. Leffell, Dermatology in General Medicine-
Fitzpatrik’s, Vol. I, 7th
ed., Mc Graw Hill, New
Delhi.
[5] Laxmipatti Sashtri, Rasayanadhikara
Yogaratanakara. Chaukhambha Sanskrit
Sanstha Publication, Vranasi.3rd
Edition
1983:pg 390.
[6] Shetty P, kedukodi P, kamath S. et.al.
Gandhaka rasayana: possible role as a
modulator of fibroblast cell function in wound
healing. Int J Health Sci Res.2020; 10(6): 36-
45.
[7] Kaviraj Govind Das Sen, Bhaishajya Ratnavli,
Edited by Mishra S, Chapter 27, Verse 82-87
pg no.580.Chaukhambha Surbharati Prakashan,
Varanasi, (Reprint ed.). 2017.
[8] Kaviraj Govind Das Sen.Bhaishajya Ratnavli,
Edited by Mishra S, Chapter 56, Verse 24-28
pg no.903.Chaukhambha Surbharati Prakashan,
Varanasi, (Reprint ed.). 2017.
[9] Dr. Brahmananda Tripathy, 2020, Sarangadhara
Samhita, madhyama khanda, 2nd
chapter.Verse
no.(137-142).
[10] Rao. P. Bhaisajya kalpana vigyan.Edition-2008,
Chaukhambha Sanskrit sansthan, 13/44, 328p.
[11] Jakhotiya Y, Kuchewar V. Ayurvedic
management of palmoplantar psoriasis. A case
study. J of Ayurveda and Hol. Med (JAHM)
2017. 5(2); 59-64P.
[12] Agnivesha, Charak, Dridhabala, Charak
Samhita ‘Vidyotini’ Hindi Commentary by
Pt.Kasinatha Sastri, Dr.Gorakhanath
Chaturvedi, Part 1 Chapter 4Ch.Su Verse 3, 13,
16 pg no-65 by Chaukhambha Bharati
Academy, Varanasi, (Reprint ed.). 2016.
[13] Di Pompo G, Poli F, Mandrone M, Lorenzi B,
Roncuzzi L, Baldini N, Granchi D.J,
Comparative “ In vitro” evaluation of the
antiresorptive activity residing in four
Ayurvedic medicinical plants ethnopharmacol.
2014 Jun 11;154(2): 462-7P.

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Ayurvedic Management of Vipadika A Case Study

  • 1. International Journal of Trend in Scientific Research and Development (IJTSRD) Volume 7 Issue 6, November-December 2023 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470 @ IJTSRD | Unique Paper ID – IJTSRD60101 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 37 Ayurvedic Management of Vipadika - A Case Study Dr. Subhashree Singha1, Prof. (Dr.) Pragya. P. Mallik2, Dr. Sonalika Jena3, Dr. Santilata Sahoo4 1 MD Scholar, PG Department of Kayachikitsa, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India 2 HOD, PG Department of Kayachikitsa, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India 3, 4 Reader, PG Department of Kayachikitsa, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India ABSTRACT Ayurveda is World’s oldest holistic healing system. According to Ayurveda Kustha Roga (Skin disorders) occurs due to an imbalance in body’s Tridosha- Vata, Pitta, Kapha. Vipadika is a Vata – Kapha predominance type of Kshudra Kustha. This can be co-related with Palmo – plantar Psoriasis in modern medical science. Palmo – Plantar Psoriasis is a relatively unknown variant of Psoriasis that affects Palm and soles of individuals of all ages. It represent 3-4% of all Psoriasis cases and is the 2nd most common type of Psoriasis followed by Chronic Plaque Psoriasis. This is a variant of Psoriasis which is resistant to many forms of treatment. The present case study is a case of 52 years patient diagnosed as Vipadika (Palmo-Plantar Psoriasis) based on its clinical sign and symptoms. In this study a treatment protocol containg Six formulations 1.Gandhaka Rasayana, 2.Rasabhra Guggulu, 3. Avipattikara Choorna, 4. Mahamanjisthadi Kwatha, 5. Karanja taila with Haridra, 6. Satadhauta Ghrita administered for 1 month. KEYWORDS: Kustha, Vipadika, Kusthaghna, Kandughna, Deepana- pachan, Varnaropana, Vedanasthapana, Sothahara How to cite this paper: Dr. Subhashree Singha | Prof. (Dr.) Pragya. P. Mallik | Dr. Sonalika Jena | Dr. Santilata Sahoo "Ayurvedic Management of Vipadika - A Case Study" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-6, December 2023, pp.37-39, URL: www.ijtsrd.com/papers/ijtsrd60101.pdf Copyright © 2023 by author (s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0) INTRODUCTION Healthy Skin is a reflection of overall health. Twak (Skin) is the largest organ of body. There is healthy skin to make an individual more confident in both mentally and physically. Now a days Twak vikara is arising due to Urbanization and Stressful life style.The disease entity named Vipadika is described in Brihatrayi . There are two types of Kustha have been described in Ayurvedic classics that is 7 Maha kustha and 11 Kshudra kustha. Vipadika is a type of Kshudra kustha1 with Vata- Kapha dosha involvement and is characterized by “Pani-Pada Sphutana and Teevra Vedana”2 by Acharya Charak. Acharya Vagbhata has stated that same features as described by Acharya Charak but mentioned one feature i.e. red patches over Palms and Soles3 . Vipadika can be co-related with Palmo-Plantar Psoriasis which is a Chronic, inflammatory disease characterized by red, itchy, scaly patches over the Palms and Soles4 . There are multiple painful cracks and bleeding also present. In modern science, it is commonly treated with corticosteroids, topical therapies, vitamins, Immune modulators. But commonly this disease relapses again and again. Through Ayurvedic treatment it can be managed without re-occurrence of the disease. CASE STUDY Center of study- OPD of Kayachikitsa Department, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India. Case report – A male patient of age 52 years came to OPD of Kayachikitsa Department, GAM, Puri with chief complaints- itching sensation, cracks and severe pain on both soles since 3 years. History of Present Illness- Complaints started with itching and slight scaling on both soles before 3 years. After few months he suffered from slight bleeding with pain on both soles. After few years, he developed cracks, severe pain & more itching sensation on both soles. He was taking different type of Modern medication, but it provided him only temporary relief. IJTSRD60101
  • 2. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD60101 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 38 Aggravating factor- Un hygienic Work Place, non- veg diet, over eating, junk food, hot and spicy food. History of Past Illness- There was no relevant past history. Family history- No member of family had such illness. Personal history-  Diet Mixed diet  Bowel Irregular  Micturition Normal  Sleep Disturbed  Addiction Tobacco On examination-  BP 130 / 86 mmHg  Pulse 78 / min  Weight 74 kg Systemic Examination-  RS-AEBE, bilateral clear  CVS- S1S2 normal  CNS- Conscious, Oriented Nidana Panchaka  Nidana • Non veg diet, Sea food • Tea (4-5 times), White flour product, Deep fried food 5 times a day • Atichintana (Stress full mind) • Divaswapna (Day sleep)  Poorva Roopa • Kandu  Roopa • Cracking of both soles, scaling, itching, bleeding and pain on both soles  Upashaya • After treatment  Samprapti • Hetu sevana • Vata – Kapha Pradhana Tridosha • Lasika (Ambu), Twak, Rakta, Mamsa • Lakshanotapatti Samprapti Ghataka  Dosha – Vata – Kapha Pradhana Tridosha  Dushya – Lasika, Twak, Rakta, Mamsa  Srotos – Rasa, Rakta, Mamsa, Sweda vaha Srotos  Sroto dusti – Sanga, Vimarga gamana  Agni- Mandagni  Vyadhi Marga – Bahya TREATMENT PROTOCOL Name of the Drug Dose Duration Gandhaka Rasayana 125 mg Twice a day with luke warm water, After food Rasabhra Guggulu 500 mg Twice a day with luke warm water, After food Avipattikara Choorna 5 gm Twice a day with luke warm water, before food Mahamanjisthadi Kwatha 15 ml Twice a day with equal amount of water After meal Karanja taila + Haridra Sufficient quantity Externally Satadhauta ghrta Sufficient quantity Externally Advice – Patient was advised to take care of his soles.  Maintain Proper hygiene  Always wear soft sleeper  Clean with luke warm water Fig. 1- Before Treatment Fig. 2- After Treatment Fig. 3- After Treatment RESULT After 1month of Proper medication the symptoms like cracking of both soles, itching, scaling, bleeding from cracked region reduced. The patient was advised for follow up and avoiding fried food items, non-vegetarian food & sea food.
  • 3. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD60101 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 39 DISCUSSION Gandhaka Rasayana5, 6 - It is useful in various skin diseases such as Eczema, Psoriasis, several types of wounds. It is very much effective towards curing abscesses and Chronic non healing wounds. Rasabhra Guggulu7 - It acts as deepaneeya, tridoshahara, srotoshodhaka, raktadustihara, as well as good immune modulator. Its ingredients like Abhrak bhasma mainly used in kaphavata disorder, loha bhasma has lekhana guna which eliminates mala rupi kapha and drugs like jaiphala, Triphala helps to removal of vitiated doshas. Avipattikara churna8 - It contains sunthi, pippali, maricha, haritaki, vibhitaki, amalaki, ela, tejapatra, nagarmotha, vidlavana, vayavidanga, all in equal parts with 11 parts of lavanga, 44 parts of sita. It helps in Proper Deepana and Pachana, in agnimandya, Triphala is a best anti oxidant, Vidanga have properties like anti microbial activities. Mahamanjisthadi Kwatha9 - It acts as blood purifier, antioxidant with healing properties. It is used in the treatment of Skin diseases due to its sothahara, Varnaropaka, Varnya properties Karanja taila10, 11 - Due to its Tikta, Katu rasa and Usna virya, it is Vataghna and Kaphaghna . It is effectively used because of its Kandughna, Kusthaghna, Jantughna, Varnaropana and Vedanasthapana properties. Haridra12 - It contains katu, Tikta rasa which acts against kaphadosha. Acharya charak has mentioned haridra in Kusthaghna, Vishaghna, lekhaniya mahakashya. Satadhauta ghrta13 -Due to its Antiseptic, Antibacterial and Soothing properties it is indicated in various skin disease such as Visarpa, Kustha, Kandu etc. CONCLUSION The case study could be conclude that Ayurvedic management seems to very effective and curative over Vipadika like skin disease. From the above case, it can be said that Palmo-plantar Psoriasis can be successfully managed through Ayurvedic treatment. REFERENCES [1] Agnivesha, Charak, Dridhabala, Charak Samhita ‘Vidyotini’ Hindi Commentary by Pt.Kasinatha Sastri, Dr.Gorakhanath Chaturvedi, Part 2 Chapter 7 Ch.chi Verse 13 pg no-250 by Chaukhambha Bharati Academy, Varanasi, (Reprinted.). 2016. [2] Agnivesha, Charak, Dridhabala, Charak Samhita ‘Vidyotini’ Hindi Commentary by Pt.Kasinatha Sastri, Dr.Gorakhanath Chaturvedi, Part 2 Chapter 7 Ch.chi Verse 21- 26 pg no-252 by Chaukhambha Bharati Academy, Varanasi, (Reprinted.). 2016. [3] Vaghbhata, Astanga Hridyam of by Kaviraj Atrideva Gupta, with ‘Vidyotini’ Hindi Commentary, edited by Vaidya Yadunandana Upadhhyaya, Chapter 14 verse 22-23 pg no-371 Chaukhambha Prakashan, Varanasi, (Reprint ed.). 2018. [4] Klaus Wolff, Lowell A Goldsmith, Stephen I. Katz, Barbara A. Gilchrest, Amy Paller, David J. Leffell, Dermatology in General Medicine- Fitzpatrik’s, Vol. I, 7th ed., Mc Graw Hill, New Delhi. [5] Laxmipatti Sashtri, Rasayanadhikara Yogaratanakara. Chaukhambha Sanskrit Sanstha Publication, Vranasi.3rd Edition 1983:pg 390. [6] Shetty P, kedukodi P, kamath S. et.al. Gandhaka rasayana: possible role as a modulator of fibroblast cell function in wound healing. Int J Health Sci Res.2020; 10(6): 36- 45. [7] Kaviraj Govind Das Sen, Bhaishajya Ratnavli, Edited by Mishra S, Chapter 27, Verse 82-87 pg no.580.Chaukhambha Surbharati Prakashan, Varanasi, (Reprint ed.). 2017. [8] Kaviraj Govind Das Sen.Bhaishajya Ratnavli, Edited by Mishra S, Chapter 56, Verse 24-28 pg no.903.Chaukhambha Surbharati Prakashan, Varanasi, (Reprint ed.). 2017. [9] Dr. Brahmananda Tripathy, 2020, Sarangadhara Samhita, madhyama khanda, 2nd chapter.Verse no.(137-142). [10] Rao. P. Bhaisajya kalpana vigyan.Edition-2008, Chaukhambha Sanskrit sansthan, 13/44, 328p. [11] Jakhotiya Y, Kuchewar V. Ayurvedic management of palmoplantar psoriasis. A case study. J of Ayurveda and Hol. Med (JAHM) 2017. 5(2); 59-64P. [12] Agnivesha, Charak, Dridhabala, Charak Samhita ‘Vidyotini’ Hindi Commentary by Pt.Kasinatha Sastri, Dr.Gorakhanath Chaturvedi, Part 1 Chapter 4Ch.Su Verse 3, 13, 16 pg no-65 by Chaukhambha Bharati Academy, Varanasi, (Reprint ed.). 2016. [13] Di Pompo G, Poli F, Mandrone M, Lorenzi B, Roncuzzi L, Baldini N, Granchi D.J, Comparative “ In vitro” evaluation of the antiresorptive activity residing in four Ayurvedic medicinical plants ethnopharmacol. 2014 Jun 11;154(2): 462-7P.