A 68-year-old male patient undergoing root canal therapy becomes pale, sweaty, confused, and unresponsive with no pulse or breathing. Medical emergencies can occur unexpectedly in dental offices and it is important for staff to be prepared. Staff should be trained in first aid and CPR, have an emergency plan, take patient medical histories and vital signs at each appointment, and have an emergency kit readily available. Being prepared is the best way to handle a medical emergency should one occur in the dental office.