Autism spectrum disorder (ASD) is a developmental disability
that includes deficits in:
• Social Communication
• Social Interaction
• Repetitive Behaviors
Introduces affected parts of the brain, awareness, prevalence, and characteristics.
Autism spectrum disorder (ASD) is a developmental disability
that includes deficits in:
• Social Communication
• Social Interaction
• Repetitive Behaviors
Introduces affected parts of the brain, awareness, prevalence, and characteristics.
This Speak Hard 2012 presentation was given by two youth from northeast Missouri and was the platform keyword for reducing risk factors and strengthening protective factors in at-risk youth. The presentation addressed local efforts in northeast Missouri involving prevention activities related to suicide prevention through the production of Public Service Announcements involving universal messages in bullying and substance abuse prevention. Participants learned how to identify risk factors and what to do when a friend is asking for help.
The Madrona Group, Joe Kiser and Jason Fox, practice Living Life as a Contribution. They work to give back to a community that has given them so much. One of the ways that they will do that in 2020 is by promoting the Autism Speaks Awareness Walk.
The walk will take place on Saturday September 26th 2020 and they hope to get as many people out there joining their team as possible.
This cause is particularly special to Jason as his son is diagnosed on the spectrum. His name is Hudson and he is 8 years old in 1st grade. Hudson was nonverbal until about 8 months ago and has responded well to the many forms of therapy that have been provided to him.
Hudson is an amazing young man, incredibly smart, very funny, super courageous and brave and as sweet as can be.
If you are interested in joining our Walk Team and donating please visit: http://act.autismspeaks.org/goto/themadronagroup
Whilst sudden outbursts of behaviour such as tantrums, hitting and
kicking are part of a child’s development as long as they do not occur
frequently, some children have serious behavioural problems that can
affect their ability to lead a normal life. When this behaviour becomes a problem, it is known as Conduct Disorder (CD).
The video for this presentation is available on our Youtube channel:
https://youtube.com/allceuseducation A continuing education course for this presentation can be found at https://www.allceus.com/member/cart/index/index?c=
Unlimited Counseling CEUs for $59 https://www.allceus.com/
Specialty Certificate tracks starting at $89 https://www.allceus.com/certificate-tracks/
Live Webinars $5/hour https://www.allceus.com/live-interactive-webinars/
Linkedin: dawnelisesnipes (https://www.linkedin.com/in/dawnelisesnipes)
Pinterest: drsnipes
This Speak Hard 2012 presentation was given by two youth from northeast Missouri and was the platform keyword for reducing risk factors and strengthening protective factors in at-risk youth. The presentation addressed local efforts in northeast Missouri involving prevention activities related to suicide prevention through the production of Public Service Announcements involving universal messages in bullying and substance abuse prevention. Participants learned how to identify risk factors and what to do when a friend is asking for help.
The Madrona Group, Joe Kiser and Jason Fox, practice Living Life as a Contribution. They work to give back to a community that has given them so much. One of the ways that they will do that in 2020 is by promoting the Autism Speaks Awareness Walk.
The walk will take place on Saturday September 26th 2020 and they hope to get as many people out there joining their team as possible.
This cause is particularly special to Jason as his son is diagnosed on the spectrum. His name is Hudson and he is 8 years old in 1st grade. Hudson was nonverbal until about 8 months ago and has responded well to the many forms of therapy that have been provided to him.
Hudson is an amazing young man, incredibly smart, very funny, super courageous and brave and as sweet as can be.
If you are interested in joining our Walk Team and donating please visit: http://act.autismspeaks.org/goto/themadronagroup
Whilst sudden outbursts of behaviour such as tantrums, hitting and
kicking are part of a child’s development as long as they do not occur
frequently, some children have serious behavioural problems that can
affect their ability to lead a normal life. When this behaviour becomes a problem, it is known as Conduct Disorder (CD).
The video for this presentation is available on our Youtube channel:
https://youtube.com/allceuseducation A continuing education course for this presentation can be found at https://www.allceus.com/member/cart/index/index?c=
Unlimited Counseling CEUs for $59 https://www.allceus.com/
Specialty Certificate tracks starting at $89 https://www.allceus.com/certificate-tracks/
Live Webinars $5/hour https://www.allceus.com/live-interactive-webinars/
Linkedin: dawnelisesnipes (https://www.linkedin.com/in/dawnelisesnipes)
Pinterest: drsnipes
historia, epidemiologia, fisiopatologia, clinica, diagnostico y tratamiento para el sindrome metabolico.
importante reconocerlo para dar tratamiento adecuado y a tiempo para asi reducir el riesgo de enfermedad cardiovascular
This is a project for an AP Psychology course. This is a fictionalized account of having a psychological ailment.
For questions about this blog project or its content please email the teacher, Laura Astorian: laura.astorian@cobbk12.org.
Autism Spectrum Disorder: Its Affects on African Americans and the Preschool ...JenniferPrice102
Autism Spectrum Disorder (ASD) affects children of all races, ethnicities and income levels; yet, African American children receive an autism diagnosis later in life than white children. Additionally, when African American children are diagnosed with a disability, they are more often diagnosed with behavioral disabilities, such as conduct disorder, oppositional defiance disorder, or ADHD. There are negative attributes associated with these disabilities, which subsequently affect how the children are viewed by teachers when they are behaving consistent with their disability (even if it is a wrongly-diagnosed disability). A misdiagnosis or late diagnosis combined with a diagnosis of a behavioral disability substantially increases the likelihood of a black autistic child being introduced inappropriately to the juvenile justice system.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
2. Causes
No known single
cause
There are theories
that imply that it is
caused by genetic
and heredity
A “trigger” has not
been found yet
Prevalent in all
races
3.
4. Characteristics
Issues with social skills
such as little eye contact,
resistance to being
touched, difficulty
understanding jokes, does
not have a filter, and has
issues keeping friends
Speech is abnormally loud
or quiet
Likes consistency and
habit
And many more…
5. Frequency
1 in 68 children have
autism
5 times more common in
boys
Boys- 1 in 42
Girls- 1 in 189
6.
7. Works Cited:
"Autism characteristics." List of autism
characteristics. N.p., n.d. Web. 1 Apr. 2014.
<http://www.calgaryautism.com/characteristics.htm
>.
"Causes - Autism Society." Autism Society Causes
Comments. N.p., n.d. Web. 1 Apr. 2014.
<http://www.autism-society.org/about-
autism/causes/>.
"Data & Statistics." Centers for Disease Control and
Prevention. Centers for Disease Control and
Prevention, 24 Mar. 2014.Web. 1 Apr. 2014.
<http://www.cdc.gov/ncbddd/autism/data.html>.