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Atropisomerism

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Pradeep Swarnkar

B.Pharm iv sem. Pharmaceutical Organic Chemistry III

Health & Medicine
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KOTA COLLEGE OF PHARMACY Atropisomerism in biphenyl compounds Mr. Pradeep Swarnkar Associate Professor
• Atropisomers are the stereoisomers in which rotation hindered about a single bond. • The isomers have difference energy of stability due to steric strain or a barrier to rotation. • The stability of the structure allow isomers to isolation individually.
Atropisomerism
Atropisomerism
Atropisomerism
Atropisomerism

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Atropisomerism

  • 1. KOTA COLLEGE OF PHARMACY Atropisomerism in biphenyl compounds Mr. Pradeep Swarnkar Associate Professor
  • 2.
  • 3. • Atropisomers are the stereoisomers in which rotation hindered about a single bond. • The isomers have difference energy of stability due to steric strain or a barrier to rotation. • The stability of the structure allow isomers to isolation individually.