BP607 Medicinal Chemistry-III

1. Mr. Pradeep Swarnkar
Associate Professor

2. Chemistry wet laboratories contain certain inherent dangers and hazards. As a chemistry
student working in a laboratory, you must learn how to work safely with these hazards in
order to prevent injury to yourself and others around you. You must make a constant
effort to think about the potential hazards associated with what you are doing, and to
think about how to work safely to prevent or minimize these hazards as much as
possible. The following guidelines are here to help you. Please understand and follow
these guidelines and act according to the principles behind them to help everybody to be
as safe as possible. Ultimately, your own safety is your own responsibility. Please make
sure you are familiar with the safety precautions, hazard warnings and procedures of the
experiment you are performing on a given day before you start any work. If you are
unsure of how to do something safely, please ask the TA before proceeding. Experiments
should not be performed without an instructor in attendance and must not be left
unattended while in progress. No unauthorized experiments are allowed. No modification
of the experiments is allowed. No work outside of regular hours is allowed, except under
exceptional circumstances.

3. SAFETY RULES

4. • Make sure you are familiar with all the safety information given
to you about each experiment before starting the experiment.
This includes your manual, these safety guidelines, any posted
information or any other information provided to by your TA.
• Always wear safety glasses (including during check-in and
check-out), except when their removal has been specifically
authorized by the TA prior to their removal. Contact lenses are
forbidden. You must also wear a face shield when requested to
by the TA.
• You must wear a lab coat (and do it up) in all Chemistry labs.

5. • Footwear must completely cover the foot and heel (no
sandals, baby dolls, ballet flats, mules, open-toed footwear,
etc.).
• You must wear long pants (no shorts, capris, skirts, or
dresses).
• If you arrive at your Chemistry lab and do not have the
required clothing, you will be directed to rent or purchase
missing items (glasses, lab coats, disposable foot coverings
and long pants) from Chemistry Stores before you will be
allowed to participate in the lab.

6. • Loose hair must be tied back so as to be out of the way.
Dangling jewellery must be removed.
• Do not eat or drink in the lab.
• Visitors are not allowed to be in the lab.
• Please keep your work area and the common work areas tidy.
Also, please make sure the aisles, safety showers, eyewash
stations and doorways are unobstructed.

7. • Please leave all glassware, equipment, tools, etc. as clean or
cleaner than you found them.
• Please clean up spills immediately. If the spill is large or is
of a hazardous material, inform the TA immediately. Use
spill mix to absorb solvent or caustic liquids.
• Please dispose of waste properly and in a timely manner and
according to the instructions provided in your lab manual. If
you are not sure, please ask your TA for the proper method
of disposal.

8. • Wash your hands before you leave the lab.
• Do not remove chemicals or equipment from the lab except
when required to do so for analysis.
• Please notify your TA of any serious medical conditions.
• Do not wear earbuds or earphones while in the lab.

9. CHEMICAL SAFETY

10. • The vapours of many organic solvents are flammable or
combustible. Do not expose electric sparks, open flames and
heating elements to organic solvent vapours. UNLESS
OTHERWISE STATED, ASSUME ALL ORGANIC
SOLVENTS ARE FLAMMABLE.
• Many chemicals (solid, liquid or vapour) are poisonous. Do
not taste chemicals. If it is necessary to smell a chemical, do
so by fanning the vapours towards your nose. Never inhale
directly. Avoid inhaling dust or fine powders. Use fume hoods
and personal protective equipment when necessary.

11. • Do not pipet with your mouth.
• Be extremely careful when transferring, distilling or
refluxing volatile liquids.
• Do not return used chemicals back to the stock
container.
• Do not tap flasks under vacuum.

12. • Do not heat, measure or mix any chemicals in front of
your face.
• Never heat a closed system – it will act as a bomb!
• Never pour water into concentrated acid. Pour acid
slowly into water, stirring constantly. Mixing acid with
water is often exothermic.

13. • Concentrated acids and bases are stored in the fume
hood. Do not carry them to your bench.
• Make sure test tubes containing reactions are pointed
away from people, especially when they are being
heated. Pressurized gas cylinders must only be operated
by the TA.