This document discusses quality assessment in systematic reviews. It states that quality assessment is required to interpret individual study results and grade the body of evidence. The key steps of quality assessment are identifying the study design, evaluating sources of bias, and rating quality based on freedom from bias. When choosing a quality assessment tool, the most important consideration is how well it covers sources of bias. When reporting quality assessment, systematic reviewers must describe the criteria, processes used, and how overall quality ratings were generated.