The invention relates a tool, new of its kind, to deliver therapeutic substances (e.g., biomaterials, stem cells, etc.) during arthroscopic micro-invasive surgery.
A MINIATURE ROBOTIC DEVICE APPLICABLE TO A FLEXIBLE ENDOSCOPE FOR THE SURGICA...Toscana Open Research
The invention is a tool installed as cap to the tip of an endoscope. The cap contains a teleoperation robot with 2 arms which the surgeon/endoscopist can control with an ergonomic console.
The document discusses the history and development of robotic surgery. It describes how the first robotic surgery device, the PUMA 560, was used in 1985 for brain biopsies. Later systems like PROBOT and ROBODOC were developed in the late 1980s and early 1990s. The da Vinci surgical system was approved by the FDA in 2000 and is now commonly used for procedures like prostatectomies and cardiac/gynecological surgeries. The da Vinci allows surgeons to operate remotely through small incisions while magnifying their hand movements. Robotic surgery provides benefits like shorter recovery times but drawbacks include the high costs of equipment and training. New innovations continue to advance the field.
DEVELOPMENT of PROTOTYPE LAPAROSCOPIC GRASPER with HAPTIC FEEDBACKAM Publications
The introduction of robot-assisted surgery into the operating room has revolutionized the medical field.
These systems not only have the advantages of traditional minimally invasive surgery (MIS), such as reduced patient
trauma and recovery time, lower morbidity, and lower health care costs, but they also eliminate surgeon tremor,
reduce the effects of surgeon fatigue, and incorporate the ability to perform remote surgical procedures. However,
current robotic surgical systems, such as the Da Vinci™ Surgical System, lack the capability of providing force
feedback to the surgeon that is present in conventional surgery. Therefore, this lack of force feedback presents
excellent developmental opportunities for surgeons and engineers to create novel surgical tools and methods to
incorporate force feedback capabilities into these robotic surgical systems. The goal of this research is to restore force
feedback capability to the surgeon in robot-assisted surgery through a haptic interaction experience involving force
feedback from the surgical site using our novel teleoperation platform. This project will summarize our research
including: 1)The Laparoscopic tool will be mounted over robotic arm.2)The Laparoscopic grasper can be integrated
with force feedback system and tactile system.3)Incorporation of master slave technique in prototype model.4)The
sensors will be used to transmit force data to slave controller and then transmitted wirelessly to master controller
which then controlled by servo motor(force feedback device.5)Opening and closing process of Laparoscopic grasper is controlled by servo motor.
The technology consists of a contact force sensor comprising an inflatable balloon, a processing unit receiving a signal of changes in pressure or deformation in the balloon and a device for notifying the operator of the contact force signal (compliance of fabrics) calculated by the processing unit.
Most surgeons and patients agree that minimally invasive surgery is preferable to open surgery, as it results in less post-operative pain, shorter hospital stays, and easier recovery. Both laparoscopic and robotic surgery are types of minimally invasive surgery. Laparoscopic surgery involves making several small incisions to insert small tools including a video camera, while robotic surgery uses a computer-controlled robot to manipulate instruments with greater precision via a 3D high-definition video feed. Robotic surgery allows for a greater range of motion than laparoscopic surgery and enables surgeons to access more difficult to reach areas. Both result in shorter recovery times compared to traditional open surgery.
Robotic surgery uses robotic systems to assist surgeons with complex procedures. The da Vinci system is the most commonly used surgical robot. It has three components - a console where the surgeon sits, a patient-side cart with four robotic arms controlled by the surgeon, and a display for other medical staff. Robotic surgery provides benefits like improved 3D vision, more precise movements, and smaller incisions, leading to less invasive procedures and faster recovery times for patients. Robotic systems are used in various specialties like general surgery, urology, cardiothoracic surgery, and neurosurgery for procedures such as prostate removal and heart valve replacement.
Review on 'Needle-free injection technology'.
Importance and awareness on why this technology is necessary in the developing nation like India (This technology is being used in small extent in the developed nations such as USA, UK EU etc.)
Note: Due to technical glitch for the previously uploaded slide, new slide has been uploaded (Previous slide link: https://www.slideshare.net/OmkarMurtale/presentation-on-needlefree-injection-technology-by-omkar-murtale)
A MINIATURE ROBOTIC DEVICE APPLICABLE TO A FLEXIBLE ENDOSCOPE FOR THE SURGICA...Toscana Open Research
The invention is a tool installed as cap to the tip of an endoscope. The cap contains a teleoperation robot with 2 arms which the surgeon/endoscopist can control with an ergonomic console.
The document discusses the history and development of robotic surgery. It describes how the first robotic surgery device, the PUMA 560, was used in 1985 for brain biopsies. Later systems like PROBOT and ROBODOC were developed in the late 1980s and early 1990s. The da Vinci surgical system was approved by the FDA in 2000 and is now commonly used for procedures like prostatectomies and cardiac/gynecological surgeries. The da Vinci allows surgeons to operate remotely through small incisions while magnifying their hand movements. Robotic surgery provides benefits like shorter recovery times but drawbacks include the high costs of equipment and training. New innovations continue to advance the field.
DEVELOPMENT of PROTOTYPE LAPAROSCOPIC GRASPER with HAPTIC FEEDBACKAM Publications
The introduction of robot-assisted surgery into the operating room has revolutionized the medical field.
These systems not only have the advantages of traditional minimally invasive surgery (MIS), such as reduced patient
trauma and recovery time, lower morbidity, and lower health care costs, but they also eliminate surgeon tremor,
reduce the effects of surgeon fatigue, and incorporate the ability to perform remote surgical procedures. However,
current robotic surgical systems, such as the Da Vinci™ Surgical System, lack the capability of providing force
feedback to the surgeon that is present in conventional surgery. Therefore, this lack of force feedback presents
excellent developmental opportunities for surgeons and engineers to create novel surgical tools and methods to
incorporate force feedback capabilities into these robotic surgical systems. The goal of this research is to restore force
feedback capability to the surgeon in robot-assisted surgery through a haptic interaction experience involving force
feedback from the surgical site using our novel teleoperation platform. This project will summarize our research
including: 1)The Laparoscopic tool will be mounted over robotic arm.2)The Laparoscopic grasper can be integrated
with force feedback system and tactile system.3)Incorporation of master slave technique in prototype model.4)The
sensors will be used to transmit force data to slave controller and then transmitted wirelessly to master controller
which then controlled by servo motor(force feedback device.5)Opening and closing process of Laparoscopic grasper is controlled by servo motor.
The technology consists of a contact force sensor comprising an inflatable balloon, a processing unit receiving a signal of changes in pressure or deformation in the balloon and a device for notifying the operator of the contact force signal (compliance of fabrics) calculated by the processing unit.
Most surgeons and patients agree that minimally invasive surgery is preferable to open surgery, as it results in less post-operative pain, shorter hospital stays, and easier recovery. Both laparoscopic and robotic surgery are types of minimally invasive surgery. Laparoscopic surgery involves making several small incisions to insert small tools including a video camera, while robotic surgery uses a computer-controlled robot to manipulate instruments with greater precision via a 3D high-definition video feed. Robotic surgery allows for a greater range of motion than laparoscopic surgery and enables surgeons to access more difficult to reach areas. Both result in shorter recovery times compared to traditional open surgery.
Robotic surgery uses robotic systems to assist surgeons with complex procedures. The da Vinci system is the most commonly used surgical robot. It has three components - a console where the surgeon sits, a patient-side cart with four robotic arms controlled by the surgeon, and a display for other medical staff. Robotic surgery provides benefits like improved 3D vision, more precise movements, and smaller incisions, leading to less invasive procedures and faster recovery times for patients. Robotic systems are used in various specialties like general surgery, urology, cardiothoracic surgery, and neurosurgery for procedures such as prostate removal and heart valve replacement.
Review on 'Needle-free injection technology'.
Importance and awareness on why this technology is necessary in the developing nation like India (This technology is being used in small extent in the developed nations such as USA, UK EU etc.)
Note: Due to technical glitch for the previously uploaded slide, new slide has been uploaded (Previous slide link: https://www.slideshare.net/OmkarMurtale/presentation-on-needlefree-injection-technology-by-omkar-murtale)
Design of Minimal Invasive Surgical devices.pptxShajedAhmed1
This document discusses the history and types of minimally invasive surgery. It describes how minimally invasive surgery uses small incisions rather than large cuts, and how endoscopes allow surgeons to see inside the body. The main types of minimally invasive surgery are endoscopy, laparoscopy, and robot-assisted surgery. The document then provides details on the invention of the first endoscopic devices in the early 1800s, how modern endoscopes work, and important early patents for laparoscopic instruments and robotic surgery systems. It concludes by discussing challenges around patents in the surgical robotics field.
The primary objective of medical tattooing is to restore part of a patient’s physical
integrity. Moreover, the procedure seeks to assist in psychological recovery from the
physical and/or psychological consequences of disease, surgery or trauma. The method
described in this brief note marks a step forward in the field of such tattooing. The
treatment simulates reconstruction of the nail bed, as the nails of the big toes had
previously been removed through a surgical avulsion procedure. This treatment, agreed
with the physician and performed by a tattooist with proven experience in medical tattooing,
also involved the use of specific colour nuances that resulted in an extremely
realistic outcome.
This document discusses minimally invasive surgery techniques. It begins by defining minimally invasive surgery as procedures that enter the body through small openings while causing minimal damage. The document then outlines the history of laparoscopy from its earliest uses in animals in the early 1900s to the development of modern equipment like fiber optics and cameras in the 1950s. It proceeds to describe various minimally invasive procedures like laparoscopic gallbladder removal and hernia repair. Emerging techniques discussed include single-incision laparoscopic surgery, robotic-assisted surgery using the da Vinci system, and natural orifice translumenal endoscopic surgery (NOTES), which are described as providing benefits like improved cosmesis and recovery over traditional open surgery.
The Future Of Surgical Gastroenterology Trends And PredictionsHealixHospitals
Explore the evolving landscape of Surgical Gastroenterology! Uncover future trends and predictions shaping the field. Stay ahead in medical advancements.
The document describes a hand exoskeleton device invented by researchers at the Istituto Italiano di Tecnologia that is capable of guiding and assisting finger flexion and extension movements to enable grasping of objects. The exoskeleton can accommodate different hand sizes and reduce strain on joints while precisely actuating each finger segment to allow grasping unknown objects safely and comfortably without calibration. The researchers are seeking an industrial partner interested in licensing the technology covered by the granted patent.
India has over 1 billion people and is very diverse, with 22 official languages. Healthcare is centered in urban areas which house only 28% of the population. Over the past 65 years since independence, India has seen advances in fields like trauma care, with good infrastructure and trained surgeons in major cities providing care on par with international standards. However, rural healthcare remains inadequate, and trauma care system development is still needed to address transportation barriers and prioritize emergency response nationwide.
The document describes a Sterile Hospital Suite (SHS) that provides an integrated solution for sterility concerns in operating rooms. The SHS combines a touchless interactive screen, wireless electrosurgical knife, and wireless laparoscopic camera that are all controlled by a single sterile control unit. This holistic solution maximizes sterility and safety for patients, improves surgical outcomes, and streamlines workflow by removing non-value added tasks. The integrated suite provides benefits such as reduced surgery duration, highest sterility conditions, and allowing surgeons to focus on core surgical activities.
This document describes a material and treatment system for regenerating cartilage tissue in joints. The system utilizes a 3D printed composite material that is implanted using minimally invasive surgery and stimulates tissue regeneration in situ using ultrasound, without multiple interventions. The material and system could enable treatment of osteoarthritis and other degenerative diseases through stem cell-mediated regenerative techniques. The inventors are exploring partnerships with industrial companies interested in licensing the technology.
This document discusses robotics in healthcare and different robotic devices used in surgery. It begins by introducing robotics in ehealth and its role in improving patient outcomes. It then discusses how robots function in ehealth by relieving medical staff and making procedures safer. Several examples of robotic devices are provided, including ones used for surgical procedures like coronary bypass and hip replacement. The document also explores how robots are used for sterilization, UV-C disinfection, and handling of COVID-19 patients. Top robotic surgery systems and various impacts of robots in daily life are summarized at the end.
Robotic surgery involves a surgeon remotely controlling robotic surgical instruments to perform operations. The surgeon views the procedure using a control console while the robotic arms mimic the surgeon's hand movements. Some key advantages of robotic surgery include less pain and scarring for patients due to smaller incisions, faster recovery times, and improved dexterity over traditional laparoscopic techniques. However, higher costs remain a concern for widespread adoption of robotic surgery systems. Major systems include da Vinci and Zeus, which are used in various specialty areas like cardiac surgery and urology. Further research is still needed to fully evaluate robotic surgery's cost-effectiveness compared to conventional methods.
This document summarizes a study that compared four methods for sterilizing orthodontic pliers: wrapped cassettes in an M11 ultraclave sterilizer, V-shaped pouches in an M11 ultraclave, wrapped cassettes in a Statim 5000 sterilizer, and V-shaped pouches in a Statim 5000. The study found that the most efficient method was using V-shaped pouches in the larger M11 ultraclave sterilizer, while the least efficient was using wrapped cassettes in the smaller Statim 5000 sterilizer. Following CDC guidelines and using pouches designed for hinged instruments like pliers allows for better sterilization than cassettes. While all methods
Robotic surgery uses robotic systems to assist surgeons in performing operations. The da Vinci Surgical System was the first robotic system approved by the FDA in 2000. It allows for more precise operations through miniaturized instruments controlled by the surgeon at a console. Robotic surgery offers advantages over traditional surgery like smaller incisions, less blood loss, and faster recovery times for patients. The primary reasons for using robotic surgery are improved precision and reducing risks from human error.
The object of the present invention is an under-actuated robotic hand with possible prosthetic application as well, i.e., a myoelectric hand having a number of actuators less than the number of degrees of freedom and capable of reproducing the movements of a human hand.
This document provides an overview of minimal access surgery (MAS). It defines MAS as applying modern technology to minimize surgical trauma without compromising exposure or safety. The history of MAS is traced from early laparoscopic procedures in the 1900s to developments like natural orifice transluminal endoscopic surgery (NOTES) and single incision laparoscopic surgery (SILS) more recently. The advantages of MAS include reduced pain, wounds, and recovery time compared to open surgery. Potential complications include injuries and those related to pneumoperitoneum such as arrhythmias. A variety of endoscopic, laparoscopic, and catheter-based minimal access procedures across several specialties are described in the document.
General surgery is the part of surgical science that studies patient care, principles of preventing and treating surgical infections through asepsis and antisepsis, anesthesia principles, trauma management, hemostasis, and purulent disease treatment. The key principles are anatomical access, technical possibility, and physiological permission. Asepsis aims to prevent wound contamination through sterilizing all objects touching the wound. Antisepsis eliminates microbes through mechanical, physical, chemical, and biological methods like wound debridement, light/heat, and antiseptic solutions.
Robotic surgery is a type of minimally invasive surgery. “Minimally invasive” means that instead of operating on patients through large incisions, we use miniaturized surgical instruments that fit through a series of quarter-inch incisions.
Microsurgery involves highly precise surgery performed under a microscope. It is used to reconnect small blood vessels and nerves after injuries and reconstructive procedures. Extensive training is required for surgeons to master the delicate techniques of microsurgery. Key aspects include reattaching amputated body parts, transplanting tissue flaps between areas, and repairing nerves and blood vessels down to a microscopic level. Microsurgery relies on specialized tools and sutures, as well as operating microscopes, to enable surgeons to visualize and manipulate tiny anatomical structures.
This document describes a new medical device called O.U.I. (Osmosi Ultrasonica Inversa), which uses ultrasound inverted osmosis technology to non-invasively treat localized fat deposits. It was developed through collaboration between university laboratories and a private company. The device transmits ultrasound waves into fat tissue, increasing cell membrane permeability and allowing triglycerides to be released from fat cells in a process called ultrasound inverted osmosis. The document provides technical specifications for the device and its components, including its hand probes, software, microprocessor and mobility station.
Seminário proferido por Iñigo Braceras Izagirre, do Centro de P,D e I TECNALIA (San Sebastián, Espanha) na seção UCS do Instituto Nacional de Engenharia de Superfícies, no dia 17 de abril para um público de cerca de 30 estudantes e professores.
Robotic surgery uses robotic systems to assist surgeons in performing minimally invasive surgery. The robotic systems allow for enhanced visualization, improved dexterity and precision, and smaller incisions compared to traditional open surgery. Some key benefits of robotic surgery for patients include less pain, shorter hospital stays, smaller scars, and faster recovery times. Common applications of robotic surgery include procedures in areas like cardiology, urology, gynecology, and orthopedics. While robotic surgery provides advantages, it also faces challenges like high costs and potential mechanical and software issues.
Sirit: the fascist internment system in Tuscany during World War II (1940-44)...Toscana Open Research
The research project focused on the Fascist internment system in Tuscany between 1940, when Italy joined the Second World War, and 1944, when the region was liberated by the Allied Army. During the war, the Fascist government and the Italian Social Republic adopted a series of measures restricting individual freedom. This led to the isolation, imprisonment, marginalization and control of anyone deemed dangerous for public security, even only on the basis of mere suspicion. These provisions resulted in a widespread and articulated network of internment devices that affected different categories of persons.
Sirit: Il sistema di internamento e di reclusione in Toscana (1940-1944): dal...Toscana Open Research
Il progetto di ricerca SIRIT prende in esame il sistema di internamento fascista in Toscana tra l’ingresso dell’Italia nella Seconda guerra mondiale (1940) e la liberazione della regione (1944). Durante la guerra, il governo fascista e la Repubblica Sociale Italiana adottarono una serie di misure restrittive della libertà individuale che portarono all’isolamento, alla reclusione, alla marginalizzazione e al controllo di chiunque fosse ritenuto pericoloso per l’ordine pubblico. Oggetto di ricerca di SIRIT sono proprio queste misure che si tradussero in una fitta rete di dispositivi e provvedimenti di internamento, che colpirono diverse categorie di persone
Design of Minimal Invasive Surgical devices.pptxShajedAhmed1
This document discusses the history and types of minimally invasive surgery. It describes how minimally invasive surgery uses small incisions rather than large cuts, and how endoscopes allow surgeons to see inside the body. The main types of minimally invasive surgery are endoscopy, laparoscopy, and robot-assisted surgery. The document then provides details on the invention of the first endoscopic devices in the early 1800s, how modern endoscopes work, and important early patents for laparoscopic instruments and robotic surgery systems. It concludes by discussing challenges around patents in the surgical robotics field.
The primary objective of medical tattooing is to restore part of a patient’s physical
integrity. Moreover, the procedure seeks to assist in psychological recovery from the
physical and/or psychological consequences of disease, surgery or trauma. The method
described in this brief note marks a step forward in the field of such tattooing. The
treatment simulates reconstruction of the nail bed, as the nails of the big toes had
previously been removed through a surgical avulsion procedure. This treatment, agreed
with the physician and performed by a tattooist with proven experience in medical tattooing,
also involved the use of specific colour nuances that resulted in an extremely
realistic outcome.
This document discusses minimally invasive surgery techniques. It begins by defining minimally invasive surgery as procedures that enter the body through small openings while causing minimal damage. The document then outlines the history of laparoscopy from its earliest uses in animals in the early 1900s to the development of modern equipment like fiber optics and cameras in the 1950s. It proceeds to describe various minimally invasive procedures like laparoscopic gallbladder removal and hernia repair. Emerging techniques discussed include single-incision laparoscopic surgery, robotic-assisted surgery using the da Vinci system, and natural orifice translumenal endoscopic surgery (NOTES), which are described as providing benefits like improved cosmesis and recovery over traditional open surgery.
The Future Of Surgical Gastroenterology Trends And PredictionsHealixHospitals
Explore the evolving landscape of Surgical Gastroenterology! Uncover future trends and predictions shaping the field. Stay ahead in medical advancements.
The document describes a hand exoskeleton device invented by researchers at the Istituto Italiano di Tecnologia that is capable of guiding and assisting finger flexion and extension movements to enable grasping of objects. The exoskeleton can accommodate different hand sizes and reduce strain on joints while precisely actuating each finger segment to allow grasping unknown objects safely and comfortably without calibration. The researchers are seeking an industrial partner interested in licensing the technology covered by the granted patent.
India has over 1 billion people and is very diverse, with 22 official languages. Healthcare is centered in urban areas which house only 28% of the population. Over the past 65 years since independence, India has seen advances in fields like trauma care, with good infrastructure and trained surgeons in major cities providing care on par with international standards. However, rural healthcare remains inadequate, and trauma care system development is still needed to address transportation barriers and prioritize emergency response nationwide.
The document describes a Sterile Hospital Suite (SHS) that provides an integrated solution for sterility concerns in operating rooms. The SHS combines a touchless interactive screen, wireless electrosurgical knife, and wireless laparoscopic camera that are all controlled by a single sterile control unit. This holistic solution maximizes sterility and safety for patients, improves surgical outcomes, and streamlines workflow by removing non-value added tasks. The integrated suite provides benefits such as reduced surgery duration, highest sterility conditions, and allowing surgeons to focus on core surgical activities.
This document describes a material and treatment system for regenerating cartilage tissue in joints. The system utilizes a 3D printed composite material that is implanted using minimally invasive surgery and stimulates tissue regeneration in situ using ultrasound, without multiple interventions. The material and system could enable treatment of osteoarthritis and other degenerative diseases through stem cell-mediated regenerative techniques. The inventors are exploring partnerships with industrial companies interested in licensing the technology.
This document discusses robotics in healthcare and different robotic devices used in surgery. It begins by introducing robotics in ehealth and its role in improving patient outcomes. It then discusses how robots function in ehealth by relieving medical staff and making procedures safer. Several examples of robotic devices are provided, including ones used for surgical procedures like coronary bypass and hip replacement. The document also explores how robots are used for sterilization, UV-C disinfection, and handling of COVID-19 patients. Top robotic surgery systems and various impacts of robots in daily life are summarized at the end.
Robotic surgery involves a surgeon remotely controlling robotic surgical instruments to perform operations. The surgeon views the procedure using a control console while the robotic arms mimic the surgeon's hand movements. Some key advantages of robotic surgery include less pain and scarring for patients due to smaller incisions, faster recovery times, and improved dexterity over traditional laparoscopic techniques. However, higher costs remain a concern for widespread adoption of robotic surgery systems. Major systems include da Vinci and Zeus, which are used in various specialty areas like cardiac surgery and urology. Further research is still needed to fully evaluate robotic surgery's cost-effectiveness compared to conventional methods.
This document summarizes a study that compared four methods for sterilizing orthodontic pliers: wrapped cassettes in an M11 ultraclave sterilizer, V-shaped pouches in an M11 ultraclave, wrapped cassettes in a Statim 5000 sterilizer, and V-shaped pouches in a Statim 5000. The study found that the most efficient method was using V-shaped pouches in the larger M11 ultraclave sterilizer, while the least efficient was using wrapped cassettes in the smaller Statim 5000 sterilizer. Following CDC guidelines and using pouches designed for hinged instruments like pliers allows for better sterilization than cassettes. While all methods
Robotic surgery uses robotic systems to assist surgeons in performing operations. The da Vinci Surgical System was the first robotic system approved by the FDA in 2000. It allows for more precise operations through miniaturized instruments controlled by the surgeon at a console. Robotic surgery offers advantages over traditional surgery like smaller incisions, less blood loss, and faster recovery times for patients. The primary reasons for using robotic surgery are improved precision and reducing risks from human error.
The object of the present invention is an under-actuated robotic hand with possible prosthetic application as well, i.e., a myoelectric hand having a number of actuators less than the number of degrees of freedom and capable of reproducing the movements of a human hand.
This document provides an overview of minimal access surgery (MAS). It defines MAS as applying modern technology to minimize surgical trauma without compromising exposure or safety. The history of MAS is traced from early laparoscopic procedures in the 1900s to developments like natural orifice transluminal endoscopic surgery (NOTES) and single incision laparoscopic surgery (SILS) more recently. The advantages of MAS include reduced pain, wounds, and recovery time compared to open surgery. Potential complications include injuries and those related to pneumoperitoneum such as arrhythmias. A variety of endoscopic, laparoscopic, and catheter-based minimal access procedures across several specialties are described in the document.
General surgery is the part of surgical science that studies patient care, principles of preventing and treating surgical infections through asepsis and antisepsis, anesthesia principles, trauma management, hemostasis, and purulent disease treatment. The key principles are anatomical access, technical possibility, and physiological permission. Asepsis aims to prevent wound contamination through sterilizing all objects touching the wound. Antisepsis eliminates microbes through mechanical, physical, chemical, and biological methods like wound debridement, light/heat, and antiseptic solutions.
Robotic surgery is a type of minimally invasive surgery. “Minimally invasive” means that instead of operating on patients through large incisions, we use miniaturized surgical instruments that fit through a series of quarter-inch incisions.
Microsurgery involves highly precise surgery performed under a microscope. It is used to reconnect small blood vessels and nerves after injuries and reconstructive procedures. Extensive training is required for surgeons to master the delicate techniques of microsurgery. Key aspects include reattaching amputated body parts, transplanting tissue flaps between areas, and repairing nerves and blood vessels down to a microscopic level. Microsurgery relies on specialized tools and sutures, as well as operating microscopes, to enable surgeons to visualize and manipulate tiny anatomical structures.
This document describes a new medical device called O.U.I. (Osmosi Ultrasonica Inversa), which uses ultrasound inverted osmosis technology to non-invasively treat localized fat deposits. It was developed through collaboration between university laboratories and a private company. The device transmits ultrasound waves into fat tissue, increasing cell membrane permeability and allowing triglycerides to be released from fat cells in a process called ultrasound inverted osmosis. The document provides technical specifications for the device and its components, including its hand probes, software, microprocessor and mobility station.
Seminário proferido por Iñigo Braceras Izagirre, do Centro de P,D e I TECNALIA (San Sebastián, Espanha) na seção UCS do Instituto Nacional de Engenharia de Superfícies, no dia 17 de abril para um público de cerca de 30 estudantes e professores.
Robotic surgery uses robotic systems to assist surgeons in performing minimally invasive surgery. The robotic systems allow for enhanced visualization, improved dexterity and precision, and smaller incisions compared to traditional open surgery. Some key benefits of robotic surgery for patients include less pain, shorter hospital stays, smaller scars, and faster recovery times. Common applications of robotic surgery include procedures in areas like cardiology, urology, gynecology, and orthopedics. While robotic surgery provides advantages, it also faces challenges like high costs and potential mechanical and software issues.
Sirit: the fascist internment system in Tuscany during World War II (1940-44)...Toscana Open Research
The research project focused on the Fascist internment system in Tuscany between 1940, when Italy joined the Second World War, and 1944, when the region was liberated by the Allied Army. During the war, the Fascist government and the Italian Social Republic adopted a series of measures restricting individual freedom. This led to the isolation, imprisonment, marginalization and control of anyone deemed dangerous for public security, even only on the basis of mere suspicion. These provisions resulted in a widespread and articulated network of internment devices that affected different categories of persons.
Sirit: Il sistema di internamento e di reclusione in Toscana (1940-1944): dal...Toscana Open Research
Il progetto di ricerca SIRIT prende in esame il sistema di internamento fascista in Toscana tra l’ingresso dell’Italia nella Seconda guerra mondiale (1940) e la liberazione della regione (1944). Durante la guerra, il governo fascista e la Repubblica Sociale Italiana adottarono una serie di misure restrittive della libertà individuale che portarono all’isolamento, alla reclusione, alla marginalizzazione e al controllo di chiunque fosse ritenuto pericoloso per l’ordine pubblico. Oggetto di ricerca di SIRIT sono proprio queste misure che si tradussero in una fitta rete di dispositivi e provvedimenti di internamento, che colpirono diverse categorie di persone
BIO-SCULT ha condotto un censimento di tutte le opere conservate nelle sale e nei depositi di Villa Corsini, verificando e - in moltissimi casi - recuperando i numeri di inventario delle sculture, andati perduti in seguito ai danni arrecati al Museo dall’alluvione e al trasferimento a Villa Corsini della sua collezione di marmi. Si è creato un database che è diventato la base per un catalogo tridimensionale delle sculture che, grazie a ricostruzioni 3D, consente a tutti la fruizione dell'intera collezione
Il progetto ha permesso la fruizione di testi, metadati, immagini, video ed esecuzioni musicali nei luoghi turistici dell’area senese tramite lo sviluppo della Realtà Aumentata.
The MeB project, resulted from the collaboration between the Scuola Normale Superiore and the Bargello Museums. Its main objective was the development of shared, applied research, aimed at the modernization of the scientific analysis processes and art-historical study of small-scale metal production of the Early Modern age. Moreover, it aimed at elaborating new operational solutions of potential interest for similar cultural contexts, also throughout the use of 3D laser scans.
Il progetto MeB, frutto della collaborazione tra la Scuola Normale Superiore e i Musei del Bargello, ha avuto come principale obiettivo quello di sviluppare una ricerca condivisa di natura applicativa, finalizzata alla modernizzazione dei processi di analisi scientifica e studio storico-artistico della produzione metallica di piccole dimensioni d’età moderna e all’elaborazione, anche attraverso scansioni laser 3D, di soluzioni operative di potenziale interesse per analoghi contesti culturali.
L’unità di Ricerca applica due strategie di design. La prima - principale - attiene alla possibilità di garantire ad ogni persona l’utilizzo di luoghi, beni e servizi, secondo i principi dello Universal Design; la seconda - in sinergia con la prima - attiene alla predisposizione di specifici dispositivi di sostegno e di specifiche tecnologie (Assistive Technologies/Adaptive Technologies) volti a consentire a persone con particolari esigenze di tipo fisico, senso-percettivo o cognitivo una migliore qualità della vita.
Riconoscimento di minerali in luce trasmessa e riflessa o diffrazione X, studi paragenetici, determinazione di elementi maggiori e in tracce,
tecniche di microanalisi, studi di speciazione mediante tecniche di estrazione sequenziali, misurazioni di concentrazioni di Hg a livello di ultratracce
L’attività di ricerca sul tema dei beni culturali 4 0 (BBCC 4 0 si svolge su più fronti una parte si concentra sulle analisi diagnostiche dei Beni Culturali ed un’altra sul trasferimento tecnologico delle competenze e delle conoscenze. Parte della ricerca sul tema include il riutilizzo del materiale di scarto della filiera dell’estrazione e lavorazione del marmo di Carrara, ovvero polveri e sabbie di carbonato di calcio
Designing and monitoring new learning models;
creating solutions for improving the well-being of employees;
psychometric and neurometric analyses for creating either inbound or outbound effectivecommunication strategies;
psychometric analyses of personality traits, leadership, and social interactions oncompany personnel aimed at creating predictive models of the success in relocatingresources;
human resources management.
Knowledge and tools aimed at characterizing sleep in physiological and
pathological conditions. Develops and tests approaches and tools aimed at intervening on sleep to modify its efficiency and functions.
Normative and descriptive models of reasoning, Analysis of experts’ judgment and decision-making, monitoring, counseling, and correction of toxic behaviors on social media (fake news, misinformation, conspiracy theories, etc.)
Managerial and organizational neurosciences to increase company valuesToscana Open Research
The research activity presides the application
of managerial and organizational neurosciences, psychophysiology and advanced analytical
approaches, offering possible services and applications in four business domains: Training,
Cognitive Ergonomics, Communication, Resources human
Process for obtaining levulinic acid esters, in particular alkyl levulinatesToscana Open Research
Our patented process is useful to obtain levulinic acid esters by direct alcoholysis of carbohydrates, such as C6 monosaccharides and/or polysaccharides thereof and/or chitin and/or chitosan, with a predetermined alcohol, takes place at a reaction temperature preferably between 100°C and 220°C for a time preferably between 30 and 300 minutes and in the presence of a co-solvent with specific properties, in addition to a conventional acid catalyst said alcohol and said co
solvent are preferably separated from the reaction mixture after conversion and then, recycled back to the conversion step
Procedimento per ottenere esteri dell'acido levulinico, in particolare alchil...Toscana Open Research
Il nostro processo brevettato è utile ad ottenere esteri dell’acido levulinico mediante alcolisi diretta di carboidrati, come monosaccaridi C6 e/o loro polisaccaridi e/o chitina e/o chitosano con un alcol predeterminato, ha luogo a una
temperatura di reazione preferibilmente compresa tra 100 C e 220 C per un tempo
preferibilmente compreso tra 30 e 300 minuti e in presenza, oltre che di un catalizzatore acido di tipo convenzionale, di un co solvente avente specifiche caratteristiche il suddetto alcol e detto solvente saranno preferibilmente separati
dalla miscela di reazione dopo conversione e riciclati alla fase di conversione
Materiale e sistema per il trattamento terapeutico di articolazioniToscana Open Research
L’invenzione vuole sostituire il bisogno di iniezioni ripetute per la rigenerazione dei tessuti e/o gli interventi chirurgici per la sostituzione dell’intera giunzione articolare. Si tratta di un materiale composito a base organica rilasciato da una stampante 3D integrata in un tool artroscopico.
Manoscritti e testi filosofici tra Oriente e Occidente dal Medioevo ai giorni...Toscana Open Research
Il focus di ricerca sulle zone liminari della storia della filosofia, ai confini tra civiltà diverse e spesso ritenute inevitabilmente conflittuali, permette a PhiBor di costituire un vero e proprio laboratorio vivente di interculturalità, intesa sia come interscambio tra differenti civiltà, sia come interfaccia razionale tra modelli conoscitivi distinti
The extracorporeal clearance precision measurement system allows clearance rate of extracorporeal treatments to be measured in real time and adjusted to patients’ needs.
Kits for modulation of anti-rejection therapies and early detection of neurod...Toscana Open Research
The patented technology is a nanofunctionalized device that enables the quantitative determination of the FKBP12 protein biomarker involved in many diseases. Quantification of FKBP12 in the blood allows for efficient monitoring of transplant patients and modulation of anti-rejection therapies, as well as early detection of neurodegenerative diseases. The device fills a gap by offering simple, sensitive quantification of FKBP12 directly in clinical settings. This supports proper dosing of immunosuppressive drugs for transplant patients and those with autoimmune diseases. It also enables early diagnosis of neurodegenerative conditions from easily obtained samples.
The cost of acquiring information by natural selectionCarl Bergstrom
This is a short talk that I gave at the Banff International Research Station workshop on Modeling and Theory in Population Biology. The idea is to try to understand how the burden of natural selection relates to the amount of information that selection puts into the genome.
It's based on the first part of this research paper:
The cost of information acquisition by natural selection
Ryan Seamus McGee, Olivia Kosterlitz, Artem Kaznatcheev, Benjamin Kerr, Carl T. Bergstrom
bioRxiv 2022.07.02.498577; doi: https://doi.org/10.1101/2022.07.02.498577
Discovery of An Apparent Red, High-Velocity Type Ia Supernova at 𝐳 = 2.9 wi...Sérgio Sacani
We present the JWST discovery of SN 2023adsy, a transient object located in a host galaxy JADES-GS
+
53.13485
−
27.82088
with a host spectroscopic redshift of
2.903
±
0.007
. The transient was identified in deep James Webb Space Telescope (JWST)/NIRCam imaging from the JWST Advanced Deep Extragalactic Survey (JADES) program. Photometric and spectroscopic followup with NIRCam and NIRSpec, respectively, confirm the redshift and yield UV-NIR light-curve, NIR color, and spectroscopic information all consistent with a Type Ia classification. Despite its classification as a likely SN Ia, SN 2023adsy is both fairly red (
�
(
�
−
�
)
∼
0.9
) despite a host galaxy with low-extinction and has a high Ca II velocity (
19
,
000
±
2
,
000
km/s) compared to the general population of SNe Ia. While these characteristics are consistent with some Ca-rich SNe Ia, particularly SN 2016hnk, SN 2023adsy is intrinsically brighter than the low-
�
Ca-rich population. Although such an object is too red for any low-
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cosmological sample, we apply a fiducial standardization approach to SN 2023adsy and find that the SN 2023adsy luminosity distance measurement is in excellent agreement (
≲
1
�
) with
Λ
CDM. Therefore unlike low-
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Ca-rich SNe Ia, SN 2023adsy is standardizable and gives no indication that SN Ia standardized luminosities change significantly with redshift. A larger sample of distant SNe Ia is required to determine if SN Ia population characteristics at high-
�
truly diverge from their low-
�
counterparts, and to confirm that standardized luminosities nevertheless remain constant with redshift.
Signatures of wave erosion in Titan’s coastsSérgio Sacani
The shorelines of Titan’s hydrocarbon seas trace flooded erosional landforms such as river valleys; however, it isunclear whether coastal erosion has subsequently altered these shorelines. Spacecraft observations and theo-retical models suggest that wind may cause waves to form on Titan’s seas, potentially driving coastal erosion,but the observational evidence of waves is indirect, and the processes affecting shoreline evolution on Titanremain unknown. No widely accepted framework exists for using shoreline morphology to quantitatively dis-cern coastal erosion mechanisms, even on Earth, where the dominant mechanisms are known. We combinelandscape evolution models with measurements of shoreline shape on Earth to characterize how differentcoastal erosion mechanisms affect shoreline morphology. Applying this framework to Titan, we find that theshorelines of Titan’s seas are most consistent with flooded landscapes that subsequently have been eroded bywaves, rather than a uniform erosional process or no coastal erosion, particularly if wave growth saturates atfetch lengths of tens of kilometers.
TOPIC OF DISCUSSION: CENTRIFUGATION SLIDESHARE.pptxshubhijain836
Centrifugation is a powerful technique used in laboratories to separate components of a heterogeneous mixture based on their density. This process utilizes centrifugal force to rapidly spin samples, causing denser particles to migrate outward more quickly than lighter ones. As a result, distinct layers form within the sample tube, allowing for easy isolation and purification of target substances.
Mending Clothing to Support Sustainable Fashion_CIMaR 2024.pdfSelcen Ozturkcan
Ozturkcan, S., Berndt, A., & Angelakis, A. (2024). Mending clothing to support sustainable fashion. Presented at the 31st Annual Conference by the Consortium for International Marketing Research (CIMaR), 10-13 Jun 2024, University of Gävle, Sweden.
Anti-Universe And Emergent Gravity and the Dark UniverseSérgio Sacani
Recent theoretical progress indicates that spacetime and gravity emerge together from the entanglement structure of an underlying microscopic theory. These ideas are best understood in Anti-de Sitter space, where they rely on the area law for entanglement entropy. The extension to de Sitter space requires taking into account the entropy and temperature associated with the cosmological horizon. Using insights from string theory, black hole physics and quantum information theory we argue that the positive dark energy leads to a thermal volume law contribution to the entropy that overtakes the area law precisely at the cosmological horizon. Due to the competition between area and volume law entanglement the microscopic de Sitter states do not thermalise at sub-Hubble scales: they exhibit memory effects in the form of an entropy displacement caused by matter. The emergent laws of gravity contain an additional ‘dark’ gravitational force describing the ‘elastic’ response due to the entropy displacement. We derive an estimate of the strength of this extra force in terms of the baryonic mass, Newton’s constant and the Hubble acceleration scale a0 = cH0, and provide evidence for the fact that this additional ‘dark gravity force’ explains the observed phenomena in galaxies and clusters currently attributed to dark matter.
JAMES WEBB STUDY THE MASSIVE BLACK HOLE SEEDSSérgio Sacani
The pathway(s) to seeding the massive black holes (MBHs) that exist at the heart of galaxies in the present and distant Universe remains an unsolved problem. Here we categorise, describe and quantitatively discuss the formation pathways of both light and heavy seeds. We emphasise that the most recent computational models suggest that rather than a bimodal-like mass spectrum between light and heavy seeds with light at one end and heavy at the other that instead a continuum exists. Light seeds being more ubiquitous and the heavier seeds becoming less and less abundant due the rarer environmental conditions required for their formation. We therefore examine the different mechanisms that give rise to different seed mass spectrums. We show how and why the mechanisms that produce the heaviest seeds are also among the rarest events in the Universe and are hence extremely unlikely to be the seeds for the vast majority of the MBH population. We quantify, within the limits of the current large uncertainties in the seeding processes, the expected number densities of the seed mass spectrum. We argue that light seeds must be at least 103 to 105 times more numerous than heavy seeds to explain the MBH population as a whole. Based on our current understanding of the seed population this makes heavy seeds (Mseed > 103 M⊙) a significantly more likely pathway given that heavy seeds have an abundance pattern than is close to and likely in excess of 10−4 compared to light seeds. Finally, we examine the current state-of-the-art in numerical calculations and recent observations and plot a path forward for near-future advances in both domains.
SDSS1335+0728: The awakening of a ∼ 106M⊙ black hole⋆Sérgio Sacani
Context. The early-type galaxy SDSS J133519.91+072807.4 (hereafter SDSS1335+0728), which had exhibited no prior optical variations during the preceding two decades, began showing significant nuclear variability in the Zwicky Transient Facility (ZTF) alert stream from December 2019 (as ZTF19acnskyy). This variability behaviour, coupled with the host-galaxy properties, suggests that SDSS1335+0728 hosts a ∼ 106M⊙ black hole (BH) that is currently in the process of ‘turning on’. Aims. We present a multi-wavelength photometric analysis and spectroscopic follow-up performed with the aim of better understanding the origin of the nuclear variations detected in SDSS1335+0728. Methods. We used archival photometry (from WISE, 2MASS, SDSS, GALEX, eROSITA) and spectroscopic data (from SDSS and LAMOST) to study the state of SDSS1335+0728 prior to December 2019, and new observations from Swift, SOAR/Goodman, VLT/X-shooter, and Keck/LRIS taken after its turn-on to characterise its current state. We analysed the variability of SDSS1335+0728 in the X-ray/UV/optical/mid-infrared range, modelled its spectral energy distribution prior to and after December 2019, and studied the evolution of its UV/optical spectra. Results. From our multi-wavelength photometric analysis, we find that: (a) since 2021, the UV flux (from Swift/UVOT observations) is four times brighter than the flux reported by GALEX in 2004; (b) since June 2022, the mid-infrared flux has risen more than two times, and the W1−W2 WISE colour has become redder; and (c) since February 2024, the source has begun showing X-ray emission. From our spectroscopic follow-up, we see that (i) the narrow emission line ratios are now consistent with a more energetic ionising continuum; (ii) broad emission lines are not detected; and (iii) the [OIII] line increased its flux ∼ 3.6 years after the first ZTF alert, which implies a relatively compact narrow-line-emitting region. Conclusions. We conclude that the variations observed in SDSS1335+0728 could be either explained by a ∼ 106M⊙ AGN that is just turning on or by an exotic tidal disruption event (TDE). If the former is true, SDSS1335+0728 is one of the strongest cases of an AGNobserved in the process of activating. If the latter were found to be the case, it would correspond to the longest and faintest TDE ever observed (or another class of still unknown nuclear transient). Future observations of SDSS1335+0728 are crucial to further understand its behaviour. Key words. galaxies: active– accretion, accretion discs– galaxies: individual: SDSS J133519.91+072807.4
2. Endoscopic surgical techniques, where possible, have significant advantages over standard
surgery such as aesthetic micro-invasiveness, speed of recovery, shorter duration of
operations with the relative benefits as regards the type of anesthesia.
During endoscopic surgical operations, especially those for the regenerative treatment of
worn cartilage, it is often necessary to deliver a drug and / or a regenerative substance to
the restricted site of intervention. The prior art devices also allow to simultaneously
extrude up to three different therapeutic substances at the same time, but do not give the
surgeon the possibility of directing their application except by hand by moving the
application nozzle with the arm.
The object of the invention is a tool, new of its kind, to deliver therapeutic substances (e.g.,
biomaterials, stem cells, etc.) during arthroscopic micro-invasive surgery.
This innovative device has the ability to direct the extruder in order to improve and
maximize the efficiency of the application by the healthcare professional.
Advantages of the proposed solution are:
• Ability to direct the medical application on site thanks to the mobility of the extruder
• Simplification of operations in arthroscopy
• Ability to microstructure the material delivered in concentric layers that maximize its
functionality
Invention
6. Scuola Superiore Sant’Anna – Technology Transfer Office
Headquarters: Piazza Martiri della Libertà 33, 56127, Pisa
Web site: www.santannapisa.it
E-mail:uvr@santannapisa.it
Ufficio Regionale di Trasferimento Tecnologico
Headquarters: Via Luigi Carlo Farini, 8 50121 Firenze (FI)
E-mail: urtt@regione.toscana.it
For more information:
For more information: