Antioxidants are substances that can neutralize reactive molecules and reduce oxidative damage. They include vitamins C and E, beta-carotene, selenium, and other minerals. Free radicals are unstable atoms that can damage cells, and antioxidants help fight them. Free radicals occur naturally but can increase with factors like pollution, smoking, and sun exposure. Consuming antioxidants through foods and supplements can help combat free radicals and promote health.