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ANTIHELMINTICS
DRUGS
PRESENTED BY :
Ch.vikas
INTRODUCTION:
These drugs are used to treat
parasite infections due to flatworm
and roundworms.
They act either locally to expel
worms from the gastrointestinal tract
or systemically to eradicate species
and developmental forms of
helminths that invade organs and
tissues.
CLASSIFICATION:
1. benzimidazoles
2. Quinoline and isoquinolines
3. Piperazine derivatives
4. Vinylpyrimidines
5. Amides
6. Natural products
7. Organophosphorus
8. Imidazothiazoles
9. Nitro derivatives
1.Benzimidazoles
The benzimidazoles
are most widely
studies class of
drugs.
Thiabendazole was
introduced in 1961.
SYNTHESIS OF
ALBENDAZOLE
(VALBAZEN) :
SYNTHESIS OF OXIBENDAZOLE:
SYNTHESIS OF FLUBENDAZOLE:
2.QUINOLINE AND ISOQUINOLINES
i.PRAZIQUANTEL (BILTRICIDE) :
ii.OXAMNIQUINE (VANSIL) :
3.PIPERAZINE DERIVATIVES:
4.VINYL PYRIMIDINES:
• OXANTEL (ALFANIL) :
5.AMIDES: • NICLOSAMIDE (NICLOCIDE) :
6. NATURAL PRODUCTS : AVERMECTINS
7. ORGANOPHOSPHORUS :
• METRIFONATE (BILACIL) :
8. IMIDAZOTHIAZOLES :
• LEVAMISOLE HYDROCHLORIDE
(VIZOLE) :
9. NITRO DERIVATIVES :
• NIRIDAZOLE (AMBILHAR) :
Antihelmintics drugs

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Antihelmintics drugs