Dr. Rahul VC Tiwari - Fellowship In Orthognathic Surgery - Jubilee Mission Medical College Hospital and Research Center, Thrissur, Kerala - 30th publicationJAMDSR 6TH name
Dr. Rahul VC Tiwari - Fellowship In Orthognathic Surgery - Jubilee Mission Medical College Hospital and Research Center, Thrissur, Kerala - 30th publicationJAMDSR 6TH name
Supplemental corticosteroids for dental patients with adrenal insufficiencyR...DrKamini Dadsena
Primary Adrenal Insufficiency:
It is caused by a progressive destruction of the adrenal cortex, usually of an idiopathic nature (most commonly autoimmune), but also results from hemorrhage, sepsis, infectious diseases (such as tuberculosis, human immunodeficiency virus, cytomegalovirus and fungal infection), malignancy, adrenalectomy, amyloidosis or drugs.
Dr. Kenneth Dickie from Royal Centre of Plastic Surgery in Barrie, Ontario explained the refining experience for Ambulatory Surgery.
If you have any questions, please contact Dr. Kenneth Dickie at http://royalcentreofplasticsurgery.com/
Ambulatory Anesthesia and Non–Operating Room Anesthesia (NORA)Saeid Safari
GUIDELINES FOR AMBULATORY ANESTHESIA AND SURGERY (American Society of Anesthesiologists)
GUIDELINES FOR AMBULATORY ANESTHESIA AND SURGERY
Non–Operating Room Anesthesia (NORA)
Postoperative care is the care you receive after a surgical procedure. The type of postoperative care you need depends on the type of surgery you have, as well as your health history. It often includes pain management and wound care. Postoperative care begins immediately after surgery.
Supplemental corticosteroids for dental patients with adrenal insufficiencyR...DrKamini Dadsena
Primary Adrenal Insufficiency:
It is caused by a progressive destruction of the adrenal cortex, usually of an idiopathic nature (most commonly autoimmune), but also results from hemorrhage, sepsis, infectious diseases (such as tuberculosis, human immunodeficiency virus, cytomegalovirus and fungal infection), malignancy, adrenalectomy, amyloidosis or drugs.
Dr. Kenneth Dickie from Royal Centre of Plastic Surgery in Barrie, Ontario explained the refining experience for Ambulatory Surgery.
If you have any questions, please contact Dr. Kenneth Dickie at http://royalcentreofplasticsurgery.com/
Ambulatory Anesthesia and Non–Operating Room Anesthesia (NORA)Saeid Safari
GUIDELINES FOR AMBULATORY ANESTHESIA AND SURGERY (American Society of Anesthesiologists)
GUIDELINES FOR AMBULATORY ANESTHESIA AND SURGERY
Non–Operating Room Anesthesia (NORA)
Postoperative care is the care you receive after a surgical procedure. The type of postoperative care you need depends on the type of surgery you have, as well as your health history. It often includes pain management and wound care. Postoperative care begins immediately after surgery.
Methods: Retrospectively, the file records of the patients who underwent sleeve gastrectomy were examined. Demographic features, Body Mass Index (BMI), the mouth opening, Mallampati score, thyromental distance, sternomental distance, neck circumference measurements and videolaryngoscopic examination results were recorded Results: In a total of 140 consecutive patients (58 male, 82 female) were included in the study. The mean age of the study participants was 35.40 ± 9.78 and the mean BMI of the patients was 44.33 ± 7.52 kg/m2
. The mean mouth opening of the patients was 4.82 ± 0.54 cm
and the mean neck circumference was 43.52 ± 4.66 cm. The mean thyromental distance was 8.02 ± 1.00 cm and the mean sternomental distance was16.58 ± 1.53 cm. Difficult intubation was determined in 8 (5.7%) patients. In logistic regression analysis, age (p : 0.446), gender (p : 0.371), BMI (p : 0.947), snoring (p : 0.567), sleep apnea (p : 0.218), mouth opening (p : 0.687), thyromental distance (p :0.557), sternomental (p : 0.596) and neck circumference (p : 0.838) were not the independent predictors of difficult intubation. However, Mallampati score (p : 0.001) and preoperative direct laryngoscopy findings (p : 0.037) performed in outpatient clinic were the significant
predictors of difficult intubation. Interestingly, all patients with grade 4 laryngoscopy findings had difficult intubation.
Frequency of Anastomotic Leak in Early Versus Dealyed Oral Feeding after Elec...semualkaira
Intestinal stoma is usually performed as component of other surgical intervention for small and large bowel
pathologies. Of these temporary colostomy are commonest stomas
created for de-functioning of the distal anastomotic site to minimise the chances of leak. Colostomy is usually reversed at 8 to 12
weeks and Ileostomy closure is often considered a minor procedure but it is associated with significant morbidity and mortality
Frequency of Anastomotic Leak in Early Versus Dealyed Oral Feeding after Elec...semualkaira
Intestinal stoma is usually performed as component of other surgical intervention for small and large bowel
pathologies. Of these temporary colostomy are commonest stomas
created for de-functioning of the distal anastomotic site to minimise the chances of leak. Colostomy is usually reversed at 8 to 12
weeks and Ileostomy closure is often considered a minor procedure but it is associated with significant morbidity and mortality
Dr. Rahul VC Tiwari - Fellowship In Orthognathic Surgery - Jubilee Mission Medical College Hospital and Research Center, Thrissur, Kerala - 31st publication IJAR 1st name
Improving Outcome for the Elderly Surgical Patients in a Singapore Teaching H...Crimsonpublisherssmoaj
Improving Outcome for the Elderly Surgical Patients in a Singapore Teaching Hospital by Si Ching Lim*, Peter Chow, Peter CL Chow, Fuyin Li, Swee Sim Hiew, Lau Soy Soy and Zhang Di in Crimson Publishers: Surgical Medicine Open Access Journal
The elderly patients admitted under surgery have longer lengths of stay and develop multiple complications during their hospital stay particularly with delirium, medical complications and functional decline. A Geriatrician’s input was helpful to identify incident and postop delirium early and put in measures to improve outcome, together with better nursing care and pharmacist’s input to reduce harm from medications.
https://crimsonpublishers.com/smoaj/fulltext/SMOAJ.000537.php
For more open access journals in Crimson Publishers
Please click on: https://crimsonpublishers.com/
For more articles on Surgical Medicine Open Access Journal
Please click on link: https://crimsonpublishers.com/smoaj/index.php
Please follow the below link for our LinkedIn page
https://www.linkedin.com/company/crimsonpublishers
Bo Abrahamsen's presentation from Osteoporosis 2016: Surgically treated osteonecrosis and osteomyelitis of the jaw and oral cavity in patients highly adherent to alendronate treatment.
Find out more at: https://nos.org.uk/conference
Mandibular Third Molar Surgery in Patients with Oral Submucous Fibrosis: Mana...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. e606
Med Oral Patol Oral Cir Bucal. 2009 Nov 1;14 (11):e605-11. Anesthesia and oral surgery on disabled patients
Introduction
The mentally disabled population represents a group
with a high incidence of oral disease caused by factors
that are specific to the disability itself: high incidence
of cavities, periodontal disease, lack of hygiene habits,
cariogenic diets, drug treatments, etc. In the current
state of well-being, there is a growing social demand
for dental treatment for this group, which sometimes
requires different techniques of general anesthesia in
order for the procedure to be properly carried out. To
meet this demand, the Castilla la Mancha Health Ser-
vice (SESCAM) developed a Dental Care Plan for the
Disabled.
The aim of the different dental care programs is to treat
oral disease in these patients. In cases in which such
treatment cannot be carried out at the dental office, it
must be performed under general anesthesia. The fluent
communication between the departments of anesthesi-
ology and odontostomatology is important so as to avoid
unnecessary surgical treatments (1). Acceptance of fu-
ture dental treatments is influenced by prior experience
and an appropriate pharmacological amnesia of the dif-
ferent processes (2). In this context, it is important to
create clinical pathways for patients with special needs
who are going to be treated while under anesthesia and
/ or conscious sedation, as well as various prevention
programs. Typically, postoperative complications from
oral surgery are estimated to be approximately 7% (3),
with a significant number of prolonged awakenings af-
ter general anesthesia. However, thanks to technologi-
cal and pharmacologic advances, these numbers have
been dramatically reduced, making it possible to use
general anesthesia in various Major Ambulatory Sur-
gery (MAS) programs. The MAS in these types of pro-
cedures involves minimal alteration of the familiar and
social environment of these patients, with a low number
of anesthetic-surgical incidences.
The aim of our study was to learn about the demo-
graphic and comorbidity characteristics of the disabled
population treated in a public non-profit public hospi-
tal, as well as the results and anesthetic and surgical
incidences of a general inhalational anesthesia protocol
used in MAS.
Material and Methods
This involves a retrospective observational study con-
ducted in a public hospital during the period between
February 15, 2006 to December 31, 2007, following
the adoption of Decree 273/2004 of November 9th, re-
garding the provision of dental care to the population
of Castilla la Mancha, including disabled persons who
have certain medical conditions, and Decree 34/2006 of
March 28th, which is a modification of the previous law
and includes disabled people with no age limit (4.5).
Although the study design is retrospective, the informa-
tion about the surgical procedure of each one of the sub-
jects was generated before presenting the research; the
observation is prospective in terms of analysis, as the
population studied comprises 100% of the patients of
the group. The Department of Oral Health for Disabled
Persons (known by its Spanish acronym as USBD-D)
consists of odonto-stomatologists, hygienists, anesthe-
siologists and nurses. The patients included in the study
were all operated under the MAS program. The surgical
activity consisted of a weekly surgery. The operating
room has standard monitoring (electrocardiogram, non-
invasive and invasive blood pressure, pulse, Bispectral
Index), respirator with gas analyzer, gas extraction and
aspiration systems. The scheduling of the waiting list
and weekly surgery is handled by the odonto-stomatol-
ogists of the department.
The preoperative study in all of the patients consisted of
an evaluation by means of clinical history and amane-
sis of the airway for screening of a potentially difficult
airway, as well as evaluation of the respiratory, car-
diac and neurological functions. The laboratory tests
performed included: hemogram, coagulation and bio-
chemical testing. A chest x-ray and electrocardiogram
were performed as prescribed by the anesthesiologist.
The informed consent for administering general anes-
thesia was signed by the patient’s legal guardian. In
the cases where it was necessary, antibiotic prophylaxis
was indicated for bacterial endocarditis, and anticomi-
cial treatment was used in patients with convulsive dis-
order. Upon admission to the ward, the disabled patient
was given a face-mask in order that he/she may become
familiar with this device. Two dressings were placed
with EMLA cream for subsequent venipuncture and the
patient's guardians were given a syringe for administer-
ing the oral medication. The pre-anesthetic oral medica-
tion in aggressive patients with no history of epilepsy,
heart disease or obstructive sleep apnea, consisted of
midazolam 0.3-0.6 mg/kg, ketamine 3-6 mg/kg, and
ibuprofen 0.6 mg/kg. For the cases in which it was not
possible to administer the medication orally, midazo-
lam 0.05 mg/kg, ketamine 1.5 mg/kg and atropine 0.3
mg/kg were administered intramuscularly. Patients who
had a contraindication for the use of benzodiazepines or
ketamine as pre-medication, were given ibuprofen 0.6
mg/kg and hydroxicine 0.6 mg/kg orally.
The anesthetic technique in all of the cases was gen-
eral anesthesia by inhalation induction with sevoflurane
(CAM 6-8%) and 100% oxygen until an appropriate
level of anesthetic depth was achieved, at which point,
we proceeded to channel a peripheral path, placing sur-
gical patties with epinephrine (topical anesthesia) in the
more permeable nostril. We then administered atropine,
fentanyl at 1-1.5 µcg/kg intravenously, under direct lar-
yngoscopy or insertion of the laryngeal mask, without
using neuromuscular relaxants. Sometimes, propofol
3. e607
Med Oral Patol Oral Cir Bucal. 2009 Nov 1;14 (11):e605-11. Anesthesia and oral surgery on disabled patients
was also administered in order to improve endotracheal
intubation conditions. Finally, we placed the oropha-
ryngeal tamponade. Intubation was only performed in
conditions of apnea when we were certain that there
was not a potentially difficult airway. The anesthetic
maintenance was carried out with a dosage of sevoflu-
rane, oxygen-air and remifentanyl 0.05-0.20 μgr/kr/min
in order to maintain a Bispectral Index (BIS) between
45 and 55. At the discretion of the anesthesiologist, the pa-
tient was gassed in a controlled method or by spontaneous
breathing. Provided there was not any contraindication,
post-intubation medication consisted of antibiotic pro-
phylaxis (ampicillin 50 mg/kg), antiemetic prophylaxis
(ondasentron 0.1 mg/kg), gastric prophylaxis (ranitidine
1.5 mg/kg), preemptive analgesia (desketoprofen 0.5
mg/kg) and corticoids (dexamethasone 0.15 mg/kg).
Blood pressure was monitored non-invasively, and an
electrocardiogram, arterial saturation by pulsimetry,
and analysis of gases were performed in order to mea-
sure the percentage of halogenated anesthetic and con-
centration of CO2
inhaled at the end of exhalation, and
levels of hypnosis using BIS monitor. Fluid therapy was
with glucosaline serum 10 mL/kg. The pressure points
were cushioned and the corneas were protected. Lo-
cal or truncular anesthesia was performed by the den-
tist before beginning the surgical procedure. For cases
in which dental extractions were performed, the patient
was given paracetamol 15 mg/kg or ketorolac 0.5 mg/kg,
once the procedure was finished.
The first phase of postoperative analysis was performed
at the Post-Anesthesia Recovery Unit (PACU), and then
in the rehabilitation wards on site. After meeting the
general discharge criteria by means of modified Aldrete
test, the patient went home. For all patients, the standard
home analgesia consisted of a combination of paraceta-
mol and ibuprofen, along with gastric protection with
ranitidine, except in the case of relative or absolute con-
traindications to the use of any of the active ingredients.
Patients were given an antibiotic treatment of amoxicil-
lin-clavulanate for six days. Twenty four hours after the
hospital discharge, we called the patient’s home in order
to follow up on the progress of the patient. The patient
and family completed a satisfaction survey.
Based on each clinical history and phone interview,
we obtained the demographic characteristics (age, sex,
weight), socioeconomic status, previous dental history
and dental treatments performed, whether public or pri-
vate, etiological cause of the mental disability, degree of
mental retardation, associated comorbidity quantified
by the scale of the American Society of Anesthesiolo-
gists (ASA), assessment of the airway using the Mal-
lampati classification, method of control of the airway,
use of muscle relaxants and ketamine, preoperative and
intraoperative anesthetic or surgical incidents, assess-
ment of the level of analgesia using the visual analogue
scale (VAS), length of stay and incidences in APPU,
the replacement rate, the rate of suspensions, the rate or
number of hospitalizations, any complications that oc-
curred and the rate of satisfaction.
The replacement rate is the percentage of interventions
carried out as MAS with regard to the total number of
dental surgery procedures performed at the center. The
rate of hospitalization corresponds to patients who are
scheduled for MAS and end up requiring unplanned
hospitalization. The rate of suspensions corresponds
to those interventions not performed on the day of the
scheduled procedure. The rate of re-hospitalizations
corresponds to patients who are discharged from the
hospital and end up being hospitalized again due to a
complication that arises within a period of 7 days after
surgery.
In the gathering and handling of information, we ad-
hered to the rules regarding the discretion and respect
for patient privacy, according to the Rules of the Ethics
Committee of our hospital. Because the patients were
treated in our MAS department, and because identif-
ying information is not published, formal approval by
the Ethics Committee was not required.
The description of the qualitative data was conducted
in the form of absolute frequencies and percentages.
Quantitative data were described using the mean and
standard deviation. A descriptive and univariant analy-
sis was carried out with the tests of the t for Student
(quantitative variables) or chi2
(qualitative variables).
The values for p <0.05 were considered statistically
significant. The data was processed using the program
Stata release 7 (Stata Corp., College Station, TX).
Results
During the study period, dental care was provided at
the Department of Oral Health for Disabled Persons for
a total of 346 patients. Of these patients, 61% received
treatment at the dental clinic of the health center, where-
as the rest of the patients required treatment under gen-
eral anesthesia or are on the waiting list for surgery.
We gathered 112 oral surgery procedures that had been
performed on disabled patients who were operated un-
der general inhalational anesthesia as part of major am-
bulatory surgery. Of these cases, 8 were excluded due to
incomplete information in the medical history. During
this period, 577 fillings, 413 extractions, 179 sealants,
102 tartrectomies, 22 root canals, 17 gingivectomies
and 3 frenectomies were performed. The most frequent
pathology was cavities in 81% of patients, with an ave-
rage of 7.3 ± 4.3 cavities and a range of 1 to 14 cavities.
Cleaning of the dental plaque was the second most com-
mon pathology. The most frequent course of treatment
is conservative as opposed to extractions.
The average age of the patients was 24.07±13.17 years
old, with a range from 2 to 64 years old. Pediatric pa-
4. e608
Med Oral Patol Oral Cir Bucal. 2009 Nov 1;14 (11):e605-11. Anesthesia and oral surgery on disabled patients
Table 1. Demographic characteristics of the population studied.
5. e609
Med Oral Patol Oral Cir Bucal. 2009 Nov 1;14 (11):e605-11. Anesthesia and oral surgery on disabled patients
tients represent 27.88% of the total patient group. There
is a clear predominance of males, with a proportion of
1.73:1. The most frequent cause of disability was mental
retardation in 41 patients (39.42%). In 75% (78 cases) of
the patients treated, they presented a coexisting medi-
cal condition and the number of prescribed medications
that they were taking was 2.13 ± 1.79 per disabled per-
son. In 40.38% of the patients (42 cases), a history of
epilepsy was observed in the pre-anesthetic history. The
presence of structural heart disease was found in 8.65%
of the patients (9 cases).We did not find any statistically
significant differences between the onset of complica-
tions and the existence of a previous history of heart
disease and epilepsy. In 66.35% of the patients (69 ca-
ses), there was no history of surgery. During the prepa-
ration of the patient in pre-surgery, there were 2 minor
incidences of the disabled patient attacking the nurses.
Demographic variables such as age, sex, ASA, comor-
bidity, distance from home to the hospital, etiology and
degree of mental retardation are shown in Table 1.
General inhalational anesthesia was performed without
the use of muscle relaxants in 97.12% of the patients
(101 cases), and nasotracheal intubation was used for
89 patients. The number of difficult intubations was de-
scribed in two cases, which were resolved by placement
of a laryngeal mask on one occasion, and in another
by replacing orotracheal intubation with nasotracheal
intubation. The total number of dental procedures per-
formed was 1291, with surgery time averaging 72.69 ±
29.78 minutes per patient. The average length of stay
in the Ambulatory Surgery Unit was 140.91 ± 29.78
minutes. The main incidences that occurred in the post-
operative awakening room are reflected in Table 2.
The rate of replacement of the unit was 100% during the
study period. The suspension rate was 1.92% (2 cases),
one case due to the coexistence of blockage in the upper
respiratory tract and the other due to non-attendance of
the patient on the date of scheduled surgery. The rate of
hospitalization was 1.92% (2 cases) and in both cases, it
was due to significant bleeding from the mouth. Howe-
ver, neither patient required special treatment and both
patients were discharged from hospital within 24 hours
of being admitted; in both cases, it is related to gingi-
vectomies. The rate of re-hospitalizations was 3.84% (4
cases) and the reasons that prompted the medical atten-
tion were fever that was probably due to dental extrac-
tion, retention of urine, drowsiness that was likely due
to prescribed drugs, and an episode of psychomotor dis-
turbance. Two hospitalizations were required, although
unrelated to the surgical procedure (craniocerebral
trauma and paraphimosis).
Discussion
Mental retardation affects people of all races and social
class. The World Health Organization estimated the in-
cidence to affect 3% of the world’s population. In Spain,
it is estimated that 15% of the population has some sort
of disability, with 4-5% of the cases considered to be
Table 2. Incidences that occurred in the postoperative recovery room
6. e610
Med Oral Patol Oral Cir Bucal. 2009 Nov 1;14 (11):e605-11. Anesthesia and oral surgery on disabled patients
moderate-severe. There is a change in the behavior of
the general population towards people with disabilities
and there are health policies that emphasize the integra-
tion and inclusion of disabled persons in public and so-
cial life. Poor oral hygiene, often present in people with
disabilities, has a significant impact on their quality of
life. Dental problems are among the top ten causes that
limit the activity of disabled people, the most common
are dental cavities, tooth loss and periodontal disease
(6). The percentage of patients in our department who
required treatment under general anesthesia and the
cause of disability support that observed by other au-
thors (7). Consistent with the findings of Escribano et al
(7), cavities and cleaning of dental plaque are the most
frequent dental problems; however, in contrast, conser-
vative treatments were more frequent than extractions
in our study group.
The disabled population is entitled to receive oral health
care as a part of the Public Health Service, yet this re-
quires specialized methods in order for it to be prop-
erly implemented. Although most of the autonomous
regions offer some sort of dental care for disabled per-
sons, perhaps it can be said that the provinces of As-
turias, Extremadura and Navarre are the most advanced
in offering dental treatment to the disabled population
(7.8). Attention to disabled persons in the Community
of Castilla La Mancha currently has two dental clinics
(Albacete and Ciudad Real). Except for the conserva-
tive treatment of temporary teeth and dentures, all treat-
ments are offered without imposing any type of age
limits. Before these clinics opened their doors, the only
solution to the pathologies was surgery with multiple
extractions. Disparities in oral health conditions and ac-
cess to dental care for disabled persons have a signifi-
cant epidemiological importance, as the use of private
dentistry services is relatively low.
The MAS can be applied to all surgical procedures sub-
ject to be performed under general, regional or local
anesthesia, or sedation, and which require minor and
short-term postoperative care, allowing the patient back
to return home within a few hours after the undergoing
the procedure. The progressive expansion and maturity
of the MAS is observed with the elimination of usual
exclusion criteria, such as the distance from home, the
presence of an associated pathology, certain treatments,
physical and psychological defects (9). Thus, in our
work we found that due to the vastness of our region,
41.34% of patients (43 patients) described their usual
residence as being located more than 90 km from the
hospital and 75% of patients (100 patients) presented
associated comorbidity, not finding significant statisti-
cal differences between these variables and the rate of
complications and re-hospitalizations. Several studies
show that the incidence of medical and surgery com-
plications following dental procedures performed using
general anesthesia is minimal. In the classic study of
Nordenram (3) carried out on 1,457 patients who under-
went oral surgery, there was an incidence of bleeding
reported in 0.75% of the cases, 1.78% lower than what
we show in our series. In the aforementioned study, the
percentage of prolonged awakenings was 0.68%, while
there was no such case in our group. A possible expla-
nation may be due to technological advances and new
anesthetic drugs with a more ideal pharmacokinetics.
In this context we decided to start the program of the
Department of Oral Health for Disabled Persons in the
form of clinical surgery (not requiring hospitalization).
After implementation of the MAS in all of the disabled
patients of the Department of Oral Health for Disabled
Persons (replacement rate of 100%), we obtain a rate of
hospitalization that is less than 2% and a rate of re-hos-
pitalization is reported in 4 cases (3.84%) with minimal
severity. These figures show that the MAS in this group
is a safe and effective surgical procedure despite being
patients with high comorbidity (33.65% of the patients
were ASA III).
The families are very involved in the oral health pro-
grams of the public healthcare service, a statement con-
sistent with the existence of a rate of 1.92% suspension
and only a single case of patient not appearing for sur-
gery at our clinic.
Postoperative nausea and vomiting (PONV) along with
pain are the most frequent and significant complica-
tions associated with MAS. Both have broad repercus-
sions because they constitute the most common medi-
cal causes of delay in discharge of the patient, as well
as re-hospitalizations. In the MAS units, the incidence
of PONV varies between 3.5% and 4.6% (10). In our
group, the incidence is higher (5.76%). This value may
be explained by the use of inhalational anesthesia, which
traditionally has been associated with an increase in
PONV (11). Acute postoperative pain increases the in-
cidence of PONV (12). Is a quality indicator in the sat-
isfaction surveys, and its incidence is difficult to quan-
tify, but several authors agree that it is high. We believe
that the onset of moderate pain in only five cases (4.8%)
indicates that the strategy of local or troncular infiltra-
tion, along with systemic analgesia, is effective. The
scientific evidence that is available today allows us to
affirm that the goal of achieving an adequate postopera-
tive analgesia comfort and PONV is only achieved with
the use of analgesic techniques that are balanced or use
multiple methods, which covers drugs such as paraceta-
mol, the NSAIDs, the infiltration of the surgical wound
and peripheral nerve blocks (PNB). The use of opiates
increases the incidence of PONV (13). Complications of
soft tissue, bone, joint and nerve tissues are also rare.
In the last months of the study, ventilation with laryn-
geal mask was used in 8 cases without any notable inci-
dent, except that the surgical field was worsened and it
7. e611
Med Oral Patol Oral Cir Bucal. 2009 Nov 1;14 (11):e605-11. Anesthesia and oral surgery on disabled patients
caused discomfort to the dentist. The importance of this
instrument is its use in cases where tracheal intubation
is not possible, and one must remember the potential for
this to occur with this group, given that in 44.23% (46
cases), it was not possible to explore during the airway
during the pre-operative visit, due to lack of coopera-
tion on the part of the patient.
The literature indicates a high prevalence of adverse
events in dental practice with patients who suffer heart
problems (14). We did not find any statistically signifi-
cant differences in the occurrence of intra-postopera-
tive complications in disabled patients with and without
coexisting cardiac and neurological pathology, which
may be explained by the use of a correct preoperative
anxiolysis without ketamine, use of multimodal analge-
sia and in certain situations, refraining from the use of
local anesthetics containing epinephrine.
Collaboration and implementation of clinical pathways
between primary and specialty care in patients with dis-
abilities who require general anesthesia may improve
the results of these programs (15). The implementa-
tion of MAS, along with major advances in the field of
anesthesiology, has provided adequate oral healthcare
for disabled patients without altering the environment
of these patients, given that when applied within this
surgical method, the patients may return to their homes
within a few hours of having received the treatments
they need. Even so, Cumella (16) shows that in Eng-
land, the prevalence of untreated cavities is still very
high due to low expectations about the conditions of
oral health in people with disabilities, fear of treatment
and lack of interest from people responsible for taking
care of them. Also consistent with those findings, in our
group of pediatric patients younger than 14 years old,
only 32% of children had received oral care at a private
clinic at any previous time.
Health authorities must get involved in publicizing
health programs, especially in the most disadvantaged
sectors of the population.
References
1. Barberia E, Arenas M, Gómez B, Saavedra-Ontiveros D. An
audit of paediatric dental treatments carried out under general an-
aesthesia in a sample of Spanish patients. Community Dent Health.
2007;24:55-8.
2. Jensen B, Schröder U. Acceptance of dental care following early
extractions under rectal sedation with diazepam in preschool chil-
dren. Acta Odontol Scand. 1998;56:229-32.
3. Nordenram A. Postoperative complications in oral surgery. A
study of cases treated during 1980. Swed Dent J. 1983;7:109-14.
4. Decree 273/2004 of November 9th, regarding the provision of den-
tal care to the population of Castilla-La Mancha, with ages ranging
between 6 and 15 years old. Diario Oficial de Castilla la Mancha (Of-
ficial Journal), November 12, 2004, No 213. p.18433-4.
5. Decree 34/2006 of March 28th, modification of Decree 273/2006.
6. Escribano Hernández A, Hernández Corral T, Ruiz-Martín E,
Porteros Sánchez JA. Results of a dental care protocol for mentally
handicapped patients set in a primary health care area in Spain. Med
Oral Patol Oral Cir Bucal. 2007;12:E492-5.
7. Limeres Posse J, Vázquez García E, Medina Henríquez J, Tomás
Carmona I, Fernández Feijoo J, Diz Dios P. Pre-assessment of se-
verely handicapped patients suitable of dental treatment under gen-
eral anesthesia. Med Oral. 2003;8:353-60.
8. Bruma M, Gallardo N, De Nova J, Mourelle M ª R. Providing den-
tal care for disabled children in the Public Health System in Spain.
Med Oral 2007;12:314-319.
9. Pohl Y, Filippi A, Geiger G, Kirschner H, Boll M. Dental treatment
of handicapped patients using endotracheal anesthesia. Anesth Prog.
1996;43:20-3.
10. Gupta A, Wu CL, Elkassabany N, Krug CE, Parker SD, Fleisher
LA. Does the routine prophylactic use of antiemetics affect the inci-
dence of postdischarge nausea and vomiting following ambulatory
surgery?: A systematic review of randomized controlled trials. An-
esthesiology. 2003;99:488-95.
11. Johannesson GP, Florén M, Lindahl SG. Sevoflurane for ENT-
surgery in children. A comparison with halothane. Acta Anaesthe-
siol Scand. 1995;39:546-50.
12. Sakellaris G, Georgogianaki P, Astyrakaki E, Michalakis M,
Dede O, Alegakis A, et al. Prevention of post-operative nausea and
vomiting in children--a prospective randomized double-blind study.
Acta Paediatr. 2008;97:801-4.
13. Shirakami G, Teratani Y, Segawa H, Matsuura S, Shichino T,
Fukuda K. Omission of fentanyl during sevoflurane anesthesia de-
creases the incidences of postoperative nausea and vomiting and ac-
celerates postanesthesia recovery in major breast cancer surgery. J
Anesth. 2006;20:188-95.
14. Margaix Muñoz M, Jiménez Soriano Y, Poveda Roda R, Sarrión
G. Cardiovascular diseases in dental practice. Practical consider-
ations. Med Oral Patol Oral Cir Bucal. 2008;13:E296-302.
15. De Nova-García MJ, Martínez MR, Sanjuán CM, López NE, Ca-
baleiro EC, García YA. Program for coordinated dental care under
general anaesthesia for children with special needs. Med Oral Patol
Oral Cir Bucal. 2007;12:E569-75.
16. Cumella S, Ransford N, Lyons J, Burnham H. Needs for oral care
among people with intellectual disability not in contact with Com-
munity Dental Services. J Intellect Disabil Res. 2000;44( Pt 1):45-
52.