Androgen Insensitivity Syndrome (AIS) is a genetic condition where people have male chromosomes and male gonads but experience partial or complete feminization of the external genitals. It is caused by mutations in the androgen receptor gene that results in cells not responding properly to androgens like testosterone. People with AIS show a spectrum of physical traits from fully female to ambiguous external genitalia depending on the severity of the mutation. Testing and treatment involves genetic testing, surgery, and hormone replacement therapy, while psychological support is also important.
AIS is a genetic condition where affected people have male chromosomes and male gonads with complete or partial feminization of the external genitals
An inherited X-linked recessive disease with a mutation in the Androgen Receptor (AR) gene resulting in:Functioning Y sex chromosome and abnormality on X chromosome
Overview normal physiological development; skeletal growth, maturation of the reproductive tract, development secondary sexual characteristics, CNS maturation, personality and psychology of the female adolescent.
AIS is a genetic condition where affected people have male chromosomes and male gonads with complete or partial feminization of the external genitals
An inherited X-linked recessive disease with a mutation in the Androgen Receptor (AR) gene resulting in:Functioning Y sex chromosome and abnormality on X chromosome
Overview normal physiological development; skeletal growth, maturation of the reproductive tract, development secondary sexual characteristics, CNS maturation, personality and psychology of the female adolescent.
Part 5 of "Science & Sexuality." What can we learn about sexual development and sexual identity from XY individuals with testes who have hormone receptor molecules that don't work at all or only partly?
A genetic condition where affected people have male chromosomes and male gonads with complete or partial feminization of the external genitals
An inherited X-linked recessive disease with a mutation in the Androgen Receptor (AR) gene resulting in:
Functioning Y sex chromosome
Abnormality on X sex chromosome
Gynecologic diseases in childhood are common. This review is intended to enable careful and sound management of pediatric patients as the initial assessment is paramount to proper management.
Part 5 of "Science & Sexuality." What can we learn about sexual development and sexual identity from XY individuals with testes who have hormone receptor molecules that don't work at all or only partly?
A genetic condition where affected people have male chromosomes and male gonads with complete or partial feminization of the external genitals
An inherited X-linked recessive disease with a mutation in the Androgen Receptor (AR) gene resulting in:
Functioning Y sex chromosome
Abnormality on X sex chromosome
Gynecologic diseases in childhood are common. This review is intended to enable careful and sound management of pediatric patients as the initial assessment is paramount to proper management.
DSD (Disorders of sexual development), Intersex.pptxAhmed Nasef
this presentation contain full, easy & simple description for the various disorders of sexual differentiation (DSD),
intersex
intersexuality
true hermaphroditism
false hermaphroditism
ambiguous genitalia ( causes, how to manage)
criteria for normal male development
criteria for normal female development
sweyer syndrome
testicular feminization syndrome
5 alpha reductase deficiency
testicular regression syndrome
ovotestis
this for undergraduates, postgraduates, General practitioners, doctors, obstetricians, gynecologists& nurses,
4. Androgen Insensitivity Visuals Image 1 : A woman with an XY chromosome pattern but insensitivity to androgens Image 2 : A newborn genetic male (46XY) with complete androgen insensitivity syndrome and female external genitalia Image 1 Image 2
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8. Normal Sexual Development MALE Sex Chromosome = XY Gonads = Testes External Genitalia = Male FEMALE Sex Chromosome = XX Gonads = Ovaries Normally chromosome sex determines gonad sex which determines phenotypic sex WHAT HAPPENS IN AIS? External Genitalia = Female
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