This document summarizes the outputs and lessons learned from the AARINENA.RAIS initiative to strengthen information and communication management for rural development in the Near East and North Africa region. Key outputs included the development of a regional portal and national portals, regional thematic knowledge networks on topics like biotechnology and plant protection, and national information systems in countries like Egypt. Lessons learned stressed the importance of enabling environments, working with people not just technology, institutionalizing networks, developing a knowledge-sharing culture, facilitating networks through meetings, and ensuring sustainability.