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Environmental Health and
Household Demographics
Impacting Diarrhea and Child
Stunting in a Complex System
By
Lee Voth-Gaeddert, PhD Student
Daniel Oerther, PhD Adviser
Environmental Systems Engineer
Missouri University of Science and Technology
Twitter handle: @LeeVG11
Outline
• Diarrhea Issues
• Structural Equation Modeling
• Dan Divelbiss Research in Guatemala
• My Thesis Research in Brazil
• Child Stunting Issues
• Dissertation Research in Guatemala
• Mycotoxins
• Enteric Infections
• Time Variant Issues
• Data Collection
• Conclusion
Latent Variables
Structural Equation Modeling
Ex:
• Symptoms of disease
• Intelligence
• Depression
• SES, Educ., Health Burdens
Latent Variables Path Analysis
Structural Equation Modeling
• Direct/Indirect effects
• Regression based
• Covariance matrices
Latent Variables Path Analysis
Structural Equation Modeling
Structural Equation Model
Improved Water
Storage
Diarrheal
Occurrences
Socio-
economic
Status
Household
Education
Level
Filter Operation
and
Maintenance
Additional
Water
Treatment
Improved Water
Source
Improved
Sanitation
Soap Present in
Home
Structural Model
on Diarrhea
Quiche, Guatemala
Additional
Water
Treatment
Diarrheal
Occurrences
Socio-
economic
Status
Household
Education
Level
Filter Operation
and
Maintenance
Soap Present in
Home
Improved Water
Source
0.139
-0.122
-0.095
-0.119
-0.170
-0.169
-0.527
Quiche, Guatemala
Divelbiss et al. 2013. “Environmental Health and Household Demographics
Impact Biosand Filter Maintenance and Diarrhea in Guatemala: An Application of
Structural Equation Modeling”. Environmental Science & Tech. 47: 1638-1645
Improved Water
Storage
Diarrheal
Occurrences
Socio-
economic
Status
Household
Education
Level
Filter Operation
and
MaintenanceAdditional
Water
Treatment
Improved Water
Source
Improved
Sanitation
Soap Present in
Home
Structural Model
on Diarrhea
Para, Brazil
Socio-
economic
Status
Household
Education
Level
Filter Operation
and
Maintenance
Additional
Water
Treatment
Improved Water
Source
Improved
Sanitation
0.353
0.256
-0.344
0.094
0.401
-0.278
-0.071
-0.200
Para, Brazil
Diarrheal
Occurrences
0.277
Confirmatory Data and Tests
Secondary data used: Demographic and Health Survey data, selected by
department and demographics
Statistical techniques used: 1) Mahalanobis Taguchi Strategy, 2) Canonical
Correlation Analysis, and 3) Latent Factor Regression
Guatemala
• Education (maternal and
paternal)
• Water Source
• Family Planning and Structure
Brazil
• Education
• Sanitation
• Socio-economic Status
• Family Structure
Voth-Gaeddert et al. 2015. “Measuring multidimensional poverty in a complex
environment; identifying the sensitive links”. Procedia Engineering 107: 172-180
Improved Water
Storage
Diarrheal
Occurrences
Socio-
economic
Status
Household
Education
Level
Filter Operation
and
MaintenanceAdditional
Water
Treatment
Improved Water
Source
Improved
Sanitation
Soap Present in
Home
Structural Model
on Diarrhea
Child stunting
World Health Organization: “a failure to reach linear
growth potential as a result of suboptimal health and/or
nutritional conditions. A height that is 2 Standard
Deviations below the WHO Child Growth Standards
median”
Why is it important and why should Environmental
Engineers focus on it?
- Our measures of success (microbial prevalence,
trihalomethane (THMs), neoicotinoids, etc.) have all
been linked to child stunting
- Stunting impacts long term physical and mental societal
contributions, and can be multigenerational
Sustainable Development Goals (SDGs)
The SDGs are a [proposed] set of 17 goals and 169 targets to follow the
Millennium Development Goals, focused on global sustainable development
including ending poverty and hunger, improving health and education,
improving cities, combating climate change, and protecting our oceans and
forests. Child health underlies many goals.
What do the SDGs incorporate that is of interest to Environmental Engineers?
- These are a set of internationally negotiated areas of high importance
- Research and development play a critical role in reaching these goals
- Environmental Engineering plays a critical underlying role in a majority of
the goals
Improved Water
Storage
Diarrheal
Occurrences
Socio-
economic
Status
Household
Education
Level
Filter Operation
and
MaintenanceAdditional
Water
Treatment
Improved Water
Source
Improved
Sanitation
Soap Present in
Home
Structural Model
on Diarrhea
Improved Water
Storage
Diarrheal
Occurrences
Socio-
economic
Status
Household
Education
Level
Filter Operation
and
MaintenanceAdditional
Water
Treatment
Improved Water
Source
Improved
Sanitation
Soap Present in
Home
Improved
Water Storage
Diarrheal
Occurrences
Socio-
economi
c Status
Househol
d
Education
Level
Filter
Operation and
MaintenanceAdditional
Water
Treatment
Improved
Water Source
Improved
Sanitation
Soap Present
in Home
Environmental
Enteropathy /
Enteric Infections
Household
Mycotoxin
Burden
Environmental
Enteropathy /
Enteric Infections
Household
Mycotoxin
Burden
Child Stunting
Environmental
Enteropathy /
Enteric Infections
Child Stunting
Swaddling/
Baby Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric Intake
Environmental
Enteropathy /
Enteric Infections
Child Stunting
Swaddling/
Baby Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric Intake
Environmental
Enteropathy /
Enteric Infections
Mycotoxins
Household
Mycotoxin
Burden
Personal
storage
facilities
Selection style
of maize from
market
Food Miles/
time to
market
Nixtomalization
usage
Exposure from
market maize
Exposure
from Personal
crops
Mycotoxin
Consumption
Model
Local Climate
of Region
(temp/elev.)
Origin of
maize to
market
Women’s time
spent in field/
storage bin
SES (to buy
better maize)
Child Stunting
Swaddling/
Baby Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric Intake
Environmental
Enteropathy /
Enteric Infections
Child Stunting
Swaddling/
Baby Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric Intake
Environmental
Enteropathy /
Enteric Infections
WaSH/ Enteric Infections
WaSH Model
Environmental
Enteropathy /
Enteric Infections
Hygienic
environment/
hand washing
practices
Probability of
pathogen exposure
due to type/location
of latrine
Probability of
pathogen
exposure due to
water source
Water
Treatment
Food
Preparation
Habits
Child Stunting
Swaddling/
Baby Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric Intake
Environmental
Enteropathy /
Enteric Infections
Child
Stunting
Swaddling/
Baby
Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Environmental
Enteropahthy /
Enteric Infections
Micronutrient
IntakeBreastfeeding
Caloric
Intake
Child
Stunting
Swaddling/
Baby
Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric
Intake
Water Storage
Practice
Hygiene/ Hand
Washing
Sanitation/
Latrine Use
Water Source
Water
Treatment
Kangaroo
Cared at
Birth
Vitamin D
Levels
Swaddling
Tightness
Time Carried
(per day/
month/year)
Lack of
mobility
Swaddling Skin
Coverage
Vitamin D in
diet
Sun
Exposure
Personal
storage
facilities
Selection style of
maize from
market
Food Miles/
time to market
Nixtalization
usageExposure from
market maize
Exposure from
Personal crops
Local Climate
of Region
(temp/elev.)
Origin of maize
to market
Women’s time
spent in field/
storage bin
SES (to buy
better maize)
Skin Tone
Environmental
Enteropahthy /
Enteric Infections
Child
Stunting
Swaddling/
Baby
Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric
Intake
Water Storage
Practice
Hygiene/ Hand
Washing
Sanitation/
Latrine Use
Water Source
Water
Treatment
Kangaroo
Cared at
Birth
Vitamin D
Levels
Swaddling
Tightness
Time Carried
(per day/
month/year)
Lack of
mobility
Swaddling Skin
Coverage
Vitamin D in
diet
Sun
Exposure
Personal
storage
facilities
Selection style of
maize from
market
Food Miles/
time to market
Nixtalization
usageExposure from
market maize
Exposure from
Personal crops
Local Climate
of Region
(temp/elev.)
Origin of maize
to market
Women’s time
spent in field/
storage bin
SES (to buy
better maize)
Skin Tone
Environmental
Enteropahthy /
Enteric Infections
Child
Stunting
Swaddling/
Baby
Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric
Intake
Water Storage
Practice
Hygiene/ Hand
Washing
Sanitation/
Latrine Use
Water Source
Water
Treatment
Kangaroo
Cared at
Birth
Vitamin D
Levels
Swaddling
Tightness
Time Carried
(per day/
month/year)
Lack of
mobility
Swaddling Skin
Coverage
Vitamin D in
diet
Sun
Exposure
Personal
storage
facilities
Selection style of
maize from
market
Food Miles/
time to market
Nixtalization
usageExposure from
market maize
Exposure from
Personal crops
Local Climate
of Region
(temp/elev.)
Origin of maize
to market
Women’s time
spent in field/
storage bin
SES (to buy
better maize)
Skin Tone
Example
Environmental
Enteropahthy /
Enteric Infections
Child
Stunting
Swaddling/
Baby
Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric
Intake
Hygiene/ Hand
Washing
Sanitation/
Latrine Use
Vitamin D
Levels
Time Carried
(per day/
month/year)
Lack of
mobility
Sun
Exposure
Exposure from
market maize
Origin of maize
to market
Example
Environmental
Enteropahthy /
Enteric Infections
Child
Stunting
Time Carried
(per day/
month/ year)
Pre-natal
Maternal
Health
Origin of
maize to
market
Micronutrient
IntakeBreastfeeding
Caloric
Intake
Hygiene/ Hand
Washing
Sanitation/
Latrine Use
Example
Environmental
Enteropahthy /
Enteric Infections
• Analysis uses structural equation modeling which is based on
regression analysis
• Temporal issues are a key driver in understanding a system (i.e.
feedback loops, lags/delays, oscillatory variables, etc.)
• Primary temporal issues could be; seasonality of rains, harvest, food
security, diet, others?
• How does that affect child stunting?
Time Variant Issues
FEWSNET 2010
Guatemalan Seasonal
Fluctuations
Structural Equation Model to System Dynamics Model
Child
Stunting
Swaddling/
Baby
Wearing
Pre-natal
Maternal
Health
Household
Mycotoxin
Burden
Micronutrient
IntakeBreastfeeding
Caloric
Intake
• Regression/probability based equations
• Parameter estimates & confidence intervals
• Cross sectional/static
• Differential equation based equations
• Feedback loops with stocks and flows
• Time variant/dynamic
Child
stunting
Mycotoxin
Nutrition
intervention
Becoming
sicker
Becoming
healthier
Breast-
feeding
Baby
wearing
% household
$$ spent on
healthcare
Enteric
infections
Micronutrient
intake
Caloric
intake
Access to
nutritious
foods
Poor
prenatal
health
Environmental
Enteropahthy /
Enteric Infections
• iPad or Tablet surveys uploaded to cloud
• SMS self reporting and reward system
• Simple or smart phone game with intermittent questions or tasks
• Hospital data collection through incentives
• Midwives
• Internet café/school
Data Collection Options
Goals of Research
• Synthesize academic literature on child stunting
• Identify causal factors of child stunting and potential cross cutting
solutions (technical OR non-technical)
• Find cost effective solutions AND cost effective assessments
• Bridge the gap between SEM (frequentist/bayesian statistics) and
SDM (differential equation based dynamics)
Acknowledgements
Funding:
• John A. and Susan Mathis Grant
• Chancellors Fellow Scholarship
• NCAA Postgraduate Scholarship
• Schowalter Foundation Grant
Persons:
• Gil Serique
• Tommy Goodwin
• Andrew Schrank
• Gerber and Michelle Perez,
Mission Impact
• Mennonite Central Committee
Thank you
lv6w3@mst.edu
@LeeVG11
Leevg11.wordpress.com

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American Chemical Society Presentation on Diarrhea and Child Stunting

Editor's Notes

  1. SES also might effect ‘exposure from market maize’ by having access to more, if you have the money, why grow it your self? Possibly at a certain level of SES (upper end) or those that soley rely on markets (80% and up), then look at relationship (control for confounder).
  2. SES and HEL has been shown not to be a factor in this issue due to the wide spread nature of it (Gong et al. 2004). More towards the cultural practices pathway model…