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Definition of respiratory distress
• At least 2 of the following
1) Heart rate >120% of the usual rate for > 5
min and/or systolic BP >180 or < 90 mmHg
and/or systolic BP changes > 20% of the
previous value for > 5 min
2) Respiratory rate >40 breaths/min
3) Marked use of accessory muscles
4) Diaphoresis
5) Abdominal paradox
6) Marked complaint of dyspnea
Initial settings: 70% assist
PEEP at least 5 cmH2O
FIO2<50%-60%
Condition 1 Condition 2 Condition 3 Condition 4
No respiratory distress
RR<35 b/min
VT>5 ml/Kg
SaO2 > 90%
No respiratory distress
RR>35 b/min
and/or VT<5 ml/Kg
SaO2 > 90%
Respiratory distress
Inefficient
gas exchange
(with no distress)
The patient meets criteria for assisted modes
(or for starting weaning trial)
Set up the ventilator on PAV mode
(check that ET tube size and IBW are correct)
No respiratory distress
RR<35 b/min
VT>5 ml/Kg
SaO2 > 90%
Observe for some time
(i.e. 2 hours, may be less or more)
No respiratory distress
Crs: ↔ or ↑
Rrs: ↔ or ↓
Decrease by 10-20%
No respiratory distress after 2 hrs
RR and VT: ↔
Respiratory distress
and/or marked ↑ in RR (>20-30%)
and/or marked ↓ in VT (<4 ml/kg)
Increase assist to previous value
(or slightly higher)
Further reductions in assist to be
done at less frequent intervals
(12-24 hours)
10-20% assist and PEEP ≤5 cmH2O
Consider extubation or
spontaneous breathing trial
PAV- Condition 1
No respiratory distress
RR>35 b/min
and/or VT < 5 ml/Kg
SaO2 > 90%
Close observation for 5-10 min
Respiratory distress develops
or RR increases further (>15%)
or VT decreases further (>15-20%)
No respiratory distress
RR and VT remains constant
Obtain ABGs
Inefficient
Gas exchange
Manage as Condition 3
PAV- Condition 2
Acceptable
PaO2 and PaCO2
Manage as Condition 1 Manage as Condition 4
Respiratory distress
at 70%
Increase PEEP in steps until Crs no
longer increases
No respiratory distress Respiratory distress
1) Ensure Pawthershold is 40 cmH2O
2) Check the set-up of the ventilator
3) Check the resistance of the ventilator circuit
Proceed as in Condition 1
(Gradual reduction of assist/PEEP)
PAV- Condition 3
See next algorithm
No respiratory distress Respiratory distress
Respiratory distress at 70%
(after PEEP adjustment
and proper set-up of the ventilator)
Increase % assist in steps of 5% up to 90%
and wait 15-20 breaths between steps
Some breaths become stretched out
(delayed cycling-off)
No Yes
No respiratory distress Respiratory distress
Proceed as in Condition 1
(Gradual reduction of assist/PEEP)
Switch to other mode
Stretched out breath
PAV- Condition 3 (cont.)
Inefficient gas exchange*
(assist 70% and FIO2 60%)
with no distress
↑PEEP until Crs no longer increases
↓PaO2 ↑PaCO2
↓PaO2 ↑PaO2
Switch to control modes
Gradual reduction of
assist/PEEP
(as in Condition 1)
Acidemia
(pH <7.35)
No significant acidemia
(pH>7.35)
Manage as
Condition 1
*Exclude causes of inefficient gas exchange such as pneumothorax, atelectasis and low cardiac output states
Treat accordingly
Consider switching to
control modes
Overassist prior to PAV
Metabolic alkalosis (primary
or secondary to Chronic
Hypercapnia)
PAV- Condition 4
Poor respiratory drive:
Excessive analgo-sedation
CNS disease
High CO2 set point

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Algorithms simplified (1) (1).ppt

  • 1. Definition of respiratory distress • At least 2 of the following 1) Heart rate >120% of the usual rate for > 5 min and/or systolic BP >180 or < 90 mmHg and/or systolic BP changes > 20% of the previous value for > 5 min 2) Respiratory rate >40 breaths/min 3) Marked use of accessory muscles 4) Diaphoresis 5) Abdominal paradox 6) Marked complaint of dyspnea
  • 2. Initial settings: 70% assist PEEP at least 5 cmH2O FIO2<50%-60% Condition 1 Condition 2 Condition 3 Condition 4 No respiratory distress RR<35 b/min VT>5 ml/Kg SaO2 > 90% No respiratory distress RR>35 b/min and/or VT<5 ml/Kg SaO2 > 90% Respiratory distress Inefficient gas exchange (with no distress) The patient meets criteria for assisted modes (or for starting weaning trial) Set up the ventilator on PAV mode (check that ET tube size and IBW are correct)
  • 3. No respiratory distress RR<35 b/min VT>5 ml/Kg SaO2 > 90% Observe for some time (i.e. 2 hours, may be less or more) No respiratory distress Crs: ↔ or ↑ Rrs: ↔ or ↓ Decrease by 10-20% No respiratory distress after 2 hrs RR and VT: ↔ Respiratory distress and/or marked ↑ in RR (>20-30%) and/or marked ↓ in VT (<4 ml/kg) Increase assist to previous value (or slightly higher) Further reductions in assist to be done at less frequent intervals (12-24 hours) 10-20% assist and PEEP ≤5 cmH2O Consider extubation or spontaneous breathing trial PAV- Condition 1
  • 4. No respiratory distress RR>35 b/min and/or VT < 5 ml/Kg SaO2 > 90% Close observation for 5-10 min Respiratory distress develops or RR increases further (>15%) or VT decreases further (>15-20%) No respiratory distress RR and VT remains constant Obtain ABGs Inefficient Gas exchange Manage as Condition 3 PAV- Condition 2 Acceptable PaO2 and PaCO2 Manage as Condition 1 Manage as Condition 4
  • 5. Respiratory distress at 70% Increase PEEP in steps until Crs no longer increases No respiratory distress Respiratory distress 1) Ensure Pawthershold is 40 cmH2O 2) Check the set-up of the ventilator 3) Check the resistance of the ventilator circuit Proceed as in Condition 1 (Gradual reduction of assist/PEEP) PAV- Condition 3 See next algorithm No respiratory distress Respiratory distress
  • 6. Respiratory distress at 70% (after PEEP adjustment and proper set-up of the ventilator) Increase % assist in steps of 5% up to 90% and wait 15-20 breaths between steps Some breaths become stretched out (delayed cycling-off) No Yes No respiratory distress Respiratory distress Proceed as in Condition 1 (Gradual reduction of assist/PEEP) Switch to other mode Stretched out breath PAV- Condition 3 (cont.)
  • 7. Inefficient gas exchange* (assist 70% and FIO2 60%) with no distress ↑PEEP until Crs no longer increases ↓PaO2 ↑PaCO2 ↓PaO2 ↑PaO2 Switch to control modes Gradual reduction of assist/PEEP (as in Condition 1) Acidemia (pH <7.35) No significant acidemia (pH>7.35) Manage as Condition 1 *Exclude causes of inefficient gas exchange such as pneumothorax, atelectasis and low cardiac output states Treat accordingly Consider switching to control modes Overassist prior to PAV Metabolic alkalosis (primary or secondary to Chronic Hypercapnia) PAV- Condition 4 Poor respiratory drive: Excessive analgo-sedation CNS disease High CO2 set point