Continuous Reactions at Albemarle Presentation

1. Continuous Reactions
at Albemarle
1

2. Outline
• Albemarle Capability
• Some Existing Continuous Reactions
• Bench Scale Equipment
• Multipurpose Continuous Assets
2

3. Albemarle Corporation
2011 Net Sales Distribution - $2.9 billion
• Global provider of value
Fine added technical solutions
Chemistry
25%
• Comprised of three business
Catalysts
38%
segments with balanced
product portfolios
• Proprietary technology and
service-driven business model
• Fundamentally strong margin
and cash flow businesses
Polymer
Solutions Fine Chemistry
37% Services
Go to: www.albemarle.com
3

4. We Offer
• US-based leading cGMP and custom manufacturing production
capabilities
• Full project support (Technical, Regulatory, HSE, Information
Management, Logistics)
• Extensive process development and scale-up capabilities
• Expertise in the development of complex syntheses
• Long Term Relationship / Production Partner
4

5. We Have
• Excellent safety record (top 10% of ACC)
• Innovative technical staff that says YES!
• FDA registered facilities with no 483s in last inspections
• ISO certified custom manufacturing facilities
• State-of-the-art analytical support
• Raw material sourcing assets in China
5

6. We Have – Manufacturing Capability
• Five Commercial Scale Multipurpose Plants
• South Haven, MI (cGMP)
• Orangeburg, SC (including cGMP)
• Tyrone, PA
• Pasadena, TX
• Baton Rouge, LA
6

7. We Have – Manufacturing Capability
• cGMP capability - kilo, pilot and commercial
• 25 L to 16,000 gal Reactors of all MOCs
• Distillation and Wiped Film Evaporators
• Most types of solids handling
• Full Utilities
• Cryogenic to hot oil
• Pressures to 1000 PSI
• Short lead time for Environmental Permits
7

8. We Have – Development Capability
Full Scale
Lab
Kilo Lab Pilot Plant Commercial
Synthesis
Plant
Baton Rouge, LA Baton Rouge, LA Baton Rouge, LA Baton Rouge, LA
South Haven, MI South Haven, MI South Haven, MI South Haven, MI
Tyrone, PA LLN, Belgium Tyrone, PA Tyrone , PA
LLN, Belgium Orangeburg, SC
Pasadena, TX
Customer Driven
8

9. Albemarle Continuous Capability
• Over 40 years of Experience
• World Scale Plants (100’s to >10,000’s TPY)
• Existing processes at Multiple Plants
• Long Term Supply
• Proven Record with Recent Successes
9

10. Ag Chemical
• Long Term Relationship
• Expanding as Customer Grows
• Started <500 TPY
• Debottlenecked existing asset to > 1500 TPY
• Further capacity increase with new asset
• Process Includes
• Hazardous Chemicals
10

11. Brominated Flame Retardant
• World Scale plant
• Complex process
• All Unit Ops Integrated
11

12. Personal Care Intermediates
• Multiple Products
• Tubular Plug Flow / High Pressure
• Long Term Supplier
12

13. Pyrophorics
• Multiple Products
• Extremely Exothermic
• Adiabatic Temperature Rise > 2000 °C
• Unique Technical Solutions
• Long Term Supplier
13

14. Custom Lubricant Production
• Albemarle selected as Scale up Partner
• Commercial Plant Operational in 21 months
• 15,000 TPY established in first month
• Scale up from Lab Directly to Commercial
• No Pilot Plant
14

15. Bench Scale Equipment
• We have a Modular Multipurpose Apparatus
• Multiple Reactor Configurations
• Currently up to 3 different feed streams
• CSTR (single or series)
• Tubular Fixedbed
• Tubular Plug Flow
15

16. Bench Scale Equipment
• Temperature range
• –100 to 200 C with circulators
• higher with electric heating
• Pressure range
• Vacuum to 1000 PSI
• >1000 PSI in High Pressure Lab
• Feed rates
• 1 g/min to 100 g/min
16

17. Bench Scale Equipment
• Computer
Controlled
Valves
• Versatile Feed
Configurations
• Computer
Interfaced
Scales
17

18. Bench Scale Equipment
18

19. Small Pilot Scale Equipment
Continuous Loop Type CFR
Distillation
Feed Pumps
19

20. Skid Mount Pilot Unit
20

21. Multipurpose Continuous Assets
• Existing Idle Equipment with World Scale Logistics
Support (rail and ship)
• Distillation Columns (100 PSI, 300 C)
• Continuous Hydrogenation Columns (500 PSI)
• High Pressure Reactors(1000 PSI, 300 C)
21

22. Why Choose Albemarle?
• Successfully Partner with both Small and Large
Companies
• Leading cGMP and Custom Manufacturing Facilities
• Competency in the Development of Complex Syntheses
• Extensive Process Development and Scale-up Capabilities
22

23. Why Choose Albemarle?
• Excellent Safety and Regulatory Record
• Demonstrated Consistent Success
• Large Scale Equipment Available
• Long Term Partner
23

24. Find out how Albemarle
says YES!
to your project.
Americas Europe, Middle East, Africa
• Fine Chemistry Services • EMA Fine Chemistry Services
• Tel: +1 225 388 7402 • Tel: +32 10 48 1711
• ALBSales@albemarle.com • EMASales@albemarle.com
Web: www.Albemarle.com
24