- South-South cooperation (SSC) has evolved as some developing countries experience high growth while others remain low-growth. SSC focuses on respecting sovereignty, national ownership, non-conditionality, and mutual benefit. - Key areas for SSC in agricultural biotechnology include joint research in new technologies like CRISPR, genome mapping of crops, and developing regulatory frameworks suited to developing countries. - Open innovation models involving partnerships across sectors, as well as open data and hardware platforms, can effectively promote SSC in agricultural biotechnology.