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Age-Period-Cohort Analysis ppt.pptx
1. Age, Period & Cohort Effects
Analysis of age, birth, cohort &
period effects
SBPM Makkah
1st Oct, 2023
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19. Cohort effects
In epidemiology, a cohort effect is conceptualized as an
interaction or effect modification due to a period effect that is
differentially experienced through age-specific exposure or
susceptibility to that event or cause.
20. Cohort effect as an effect modification
In epidemiology, sociological literature consider cohort effect as
a structural factor representing the sum of all unique exposures
experienced by the cohort from birth.
In this case, age and period effect are conceived as
confounders of cohort effect and APC analysis aims to separate
the independent effect of age, period and cohort.
Most of the APC analysis strategies are based on the
sociological model of cohort effect, conceptualize independent
effect of age, period and cohort effect.
21. Detecting Cohort Effects
Cohort effects are a special interaction of age and period.
The three effects are interrelated. Once two are specified
the third is determined by the other two
Cohort effects are often hard to detect because analysis is
usually by age and period.
Cohort effects are usually seen as an elevated risk which
changes with age over time
23. Deafness In Australia
AGE 1911 1921 1933
0-4 16 17 11
5-9 59 72 95
10-14 111 86 89
15-19 64 57 141
20-24 65 117 98
25-29 60 59 69
30-34 54 67 140
35-39 57 62 71
Do you see the birth cohort effect in these data?
24. 1- The data show a peak in deafness among 10-14 years olds in
1911
2- among 20-24 year olds in 1921
3- among 30-34 year olds in 1933.
This is clearly the same cohort that is aging.
Later research showed that a rubella epidemic took place in
Australia at the same time that this cohort was in utero.
The effects of congenital rubella infection in causing sensori-neural
hearing loss were not discovered until decades later, but these data
were early evidence of the effects of the epidemic.
25. Deafness In Australia
AGE 1911 1921 1933
0-4 16 17 11
5-9 59 72 95
10-14 111 86 89
15-19 64 57 141
20-24 65 117 98
25-29 60 59 69
30-34 54 67 140
35-39 57 62 71
Do you see the birth cohort effect in these data?