A basic approach towards carcinoma of prostate , symptoms, investigations , diagnosis, staging, treatment and follow up along with recent advances in surgeries, vaccines and immunotherapy.
A basic approach towards carcinoma of prostate , symptoms, investigations , diagnosis, staging, treatment and follow up along with recent advances in surgeries, vaccines and immunotherapy.
Overview and Pharmacotherapy of Prostate Cancer (based on NCCN 2012 guideline...hyunik116
This presentation was the prostate cancer lecture for the oncology therapeutics course (31:725:560) that was presented to the class of 2014 PharmD students at the Ernest Mario School of Pharmacy.
I really enjoyed researching and preparing this lecture for the students, and hope you also will find at least something useful in this presentation.
Prostate cancer or tumor is the most common cancer in men other than non-melanoma skin cancer.
The majority (more than 75%) of cases occur in men over age 65.
Prostate cancer is a malignant tumor of the prostate gland.
early detection helps ......................................................................................................................................................................................................................................................................................................
Carcinoma of the prostate; Incidence, Epidemiology, Aetiology, Clinical features, Workup, and Management.
by Osman Altohamy, A Fifth year Medical Student, Gezira, Sudan
osmansalahe@icloud.com
osmansalahe@hotmail.com
Prostate cancer or tumor is the most common cancer in men other than non-melanoma skin cancer.
The majority (more than 75%) of cases occur in men over age 65.
Risk factors for prostate cancer including increasing age, the incidence of prostate cancer increase rapidly after the age of 50 years. And more than 70% cases occur in men older than 65 year of age.
Basic information for discussion with a healthcare professional is provided here together with some background:
• An enlargement or the presence of tumors in the gland below a man’s bladder that produces fluid for semen ie, the prostate, may suggest benign prostatic hyperplasia (BPH) or prostate cancer
o Almost 8% of new cancer cases worldwide are attributed to this highly curable disease (proportion of patients surviving after 5 years = 98.9%)
o In the USA alone, prostate cancer is the most common non-skin cancer, diagnosed more often in African-American (1 in 5 cases) than white men (1 in 6 cases)
o Prostate cancer is strongly correlated with age, starting at about 50 years old and rising over the ensuing decades
o While debates over under- or over-treatment of prostate cancer continue, it is clear that management of the disease costs the USA an aggregate annual loss in productivity of $3.0 billion
o Moreover, prostate cancer is the third-leading cause of cancer-related deaths in the USA, mainly due to advanced or metastatic disease
Overview and Pharmacotherapy of Prostate Cancer (based on NCCN 2012 guideline...hyunik116
This presentation was the prostate cancer lecture for the oncology therapeutics course (31:725:560) that was presented to the class of 2014 PharmD students at the Ernest Mario School of Pharmacy.
I really enjoyed researching and preparing this lecture for the students, and hope you also will find at least something useful in this presentation.
Prostate cancer or tumor is the most common cancer in men other than non-melanoma skin cancer.
The majority (more than 75%) of cases occur in men over age 65.
Prostate cancer is a malignant tumor of the prostate gland.
early detection helps ......................................................................................................................................................................................................................................................................................................
Carcinoma of the prostate; Incidence, Epidemiology, Aetiology, Clinical features, Workup, and Management.
by Osman Altohamy, A Fifth year Medical Student, Gezira, Sudan
osmansalahe@icloud.com
osmansalahe@hotmail.com
Prostate cancer or tumor is the most common cancer in men other than non-melanoma skin cancer.
The majority (more than 75%) of cases occur in men over age 65.
Risk factors for prostate cancer including increasing age, the incidence of prostate cancer increase rapidly after the age of 50 years. And more than 70% cases occur in men older than 65 year of age.
Basic information for discussion with a healthcare professional is provided here together with some background:
• An enlargement or the presence of tumors in the gland below a man’s bladder that produces fluid for semen ie, the prostate, may suggest benign prostatic hyperplasia (BPH) or prostate cancer
o Almost 8% of new cancer cases worldwide are attributed to this highly curable disease (proportion of patients surviving after 5 years = 98.9%)
o In the USA alone, prostate cancer is the most common non-skin cancer, diagnosed more often in African-American (1 in 5 cases) than white men (1 in 6 cases)
o Prostate cancer is strongly correlated with age, starting at about 50 years old and rising over the ensuing decades
o While debates over under- or over-treatment of prostate cancer continue, it is clear that management of the disease costs the USA an aggregate annual loss in productivity of $3.0 billion
o Moreover, prostate cancer is the third-leading cause of cancer-related deaths in the USA, mainly due to advanced or metastatic disease
This slide deck is about Prostate cancer. It is amongst the leading cause of cancer deaths in adult males. This slide deck will provide you with necessary information regarding the symptoms, risk, diagnosis, and possible treatment of prostate cancer. I hope the readers find this slide deck useful & informative
Prostate cancer is among the leading causes of cancer death among American men, second only to lung cancer. Learn more about prostate cancer and how Oklahoma CyberKnife's noninvasive treatment may work for you by calling (918) 949-6676.
Austin CyberKnife presents the American Cancer Society Facts and Figures 2014 annual report outlining the estimated numbers of new cancer cases and deaths in 2014 as well as current cancer incidence, mortality, and survival statistics and information on cancer symptoms, risk factors, early detection and treatment.
Potomac Urology is dedicated to providing personalized, state-of-the-art urology treatments with exceptional care and compassion. At Potomac Urology, we strive to bring you the best urological care along with the convenience and comfort of staying close to home.
The risk of dying from colon cancer is reduced approximately 33% among people who are screened regularly. Colonoscopy is the gold standard approach to screening for colon cancer.
Austin CyberKnife presents the American Cancer Society Facts and Figures 2013 annual report outlining the estimated numbers of new cancer cases and deaths in 2013 as well as current cancer incidence, mortality, and survival statistics and information on cancer symptoms, risk factors, early detection and treatment.
As the second-most common cancer in both men and women, lung cancer is responsible for the majority of cancer-related deaths. The American Cancer Society estimates more than 160,000 people will lose their battle with lung cancer this year, accounting for more victims than breast, prostate, colon and pancreatic cancers combined.
In recognition of National Lung Cancer Awareness Month in November, Austin CyberKnife encourages local residents to take preventive steps to protect themselves and their loved ones from common and lesser-known causes of lung cancer.
May marks the recognition of National Brain Tumor Awareness Month. Since its establishment in 2008, community organizations and support groups celebrate this month with increased efforts to raise awareness of brain tumors, increase funding for research and educate the public on symptoms and treatment options.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
1. STAGES OF PROSTATE CANCER
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
2. A
prostate
cancer
diagnosis
can
be
scary.
Learn
more
about
prostate
cancer
and
how
we
can
help.
Please
note:
The
informa1on
presented
here
is
not
all-‐inclusive.
Rather,
it
represents
a
star1ng
point
to
learn
more
about
medical
condi1ons
and
treatment
op1ons.
There
is
no
subs,tute
for
consul,ng
a
medical
professional.
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
3. Prostate Cancer Overview
Possible Signs of Prostate Cancer:
Weak or interrupted flow of urine
Frequent urination
Trouble urinating
Pain or burning during urination
Blood in the urine or semen
Persistent pain in the back, hips, or pelvis
Painful ejaculation
¨ The prostate is a
walnut-sized gland
located in a man’s
lower abdomen that
controls the flow of
urine and semen.
¨ Prostate cancer is a
leading cause of
cancer death among
American men, second
only to lung cancer.
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
4. Diagnosing Prostate Cancer
Prostate cancer can be diagnosed by:
¨ Digital Rectal Exam (DRE) – examination of
the rectum.
¨ Prostate-specific antigen (PSA) test –
measures the level of PSA in the blood. PSA
may be found in an increased amount in the
blood of men with prostate cancer.
¨ Transrectal Ultrasound – provides a picture of
the prostate for the doctor to analyze.
¨ Gleason Score – determines how likely
prostate cancer is to spread.
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
5. The TNM Staging System
A staging system describes how far a cancer has spread.
The most widely used staging system for prostate cancer is
the American Joint Committee on Cancer (AJCC) TNM
system.
The TNM system for prostate cancer is based on 5 key
pieces of information:
¤ The extent of the primary tumor (T category)
¤ Whether the cancer has spread to nearby lymph nodes (N
category)
¤ The absence or presence of distant metastasis (M category)
¤ The PSA level at the time of diagnosis
¤ The Gleason Score, based on the prostate biopsy (or surgery)
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
6. Prostate Cancer - Stage I
¨ Cancer is found in the prostate only.
¨ Cancer is microscopic and cannot be felt during the
DRE or seen on imaging tests.
¨ Cancer is found in one-half or less of one lobe of
the prostate.
¨ PSA level is lower than 10 ng/mL.
¨ Gleason Score is 6 or lower.
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
7. Prostate Cancer - Stage IIA
¨ Cancer is more advanced than
Stage I but has not spread outside
the prostate.
¨ The cells are usually more
abnormal and may tend to grow
more quickly.
¨ Cancer is found in more than half
of one lobe of the prostate.
¨ PSA level is lower than 20 ng/mL.
¨ Gleason Score is 7 or lower.
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
8. Prostate Cancer - Stage IIB
¨ Cancer is found in opposite sides of the prostate.
¨ Cancer cannot be felt during a DRE and is not
visible by imaging.
¨ The tumor has not spread outside the prostate.
¨ PSA level is 20 ng/mL or higher.
¨ Gleason Score ranges from 2 to 10.
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
9. Prostate Cancer - Stage III
¨ Cancer has spread beyond the
outer layer of the prostate.
¨ Cancer may have spread to
nearby tissues like the seminal
vesicles.
¨ PSA can be any level.
¨ Gleason Score can range from
2 to 10.
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
10. Prostate Cancer - Stage IV
¨ Cancer has spread
(metastasized) beyond the
seminal vesicles to nearby
tissues or organs such as
the rectum, bladder or
pelvic wall.
¨ Cancer has spread to
distant parts of the body,
which may include other
lymph nodes or bones.
Prostate cancer often
spreads to the bones.
¨ Cancer has spread to
nearby lymph nodes
¨ PSA can be any level.
¨ Gleason score can range
from 2 to 10.
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
11. Prostate Cancer Treatment
Treatment Options
Active Surveillance
Surgery
External-Beam Radiation Therapy
Brachytherapy
Proton Therapy
Stereotactic Body Radiation Therapy
¨ Treatment options depend on:
¤ The stage of the cancer
¤ The patient’s age and health
¤ The patient’s Gleason Score
¤ Whether the cancer is recently
diagnosed or recurring
¤ The patient’s prostate-specific
antigen (PSA) levels
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
12. CyberKnife® Treatment Process
¨ Prior to stereotactic body radiation therapy with CyberKnife, small
tissue markers known as fiducials are implanted in the prostate to
help pinpoint the tumor location throughout each treatment.
¨ About a week later, patients undergo pretreatment imaging,
including CT scans which are used by physicians in the treatments
planning process.
¨ This treatment process
includes
¤ Consultation appointment
¤ Pretreatment procedures
¤ CyberKnife treatment
¤ Follow-up
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
14. Austin CyberKnife was the first in the greater Austin area, as well as
the central Texas region, to offer CyberKnife treatment, giving our
physicians the most experience treating patients with this technology in
our area. Austin CyberKnife is a department of University Medical
Center Brackenridge, a member of the Seton Healthcare Family.
If you or a loved one is diagnosed with prostate cancer, contact Austin
CyberKnife to schedule a consultation with our physicians to determine
the best next step for your treatment needs.
Medical Director: Dr. Doug Rivera
CyberKnife Nurse: Lori Eitelbach, RN
Medical Physicist: Jim Hevezi, PhD
Our Center
1400
North
IH
35,
Austin,
TX
78701
(512)
324-‐8060
www.austincyberknife.com
Connect
With
Us