Drug degradation is the natural breakdown of drugs over time due to environmental factors like light, heat, humidity, and air exposure. This can reduce the potency and effectiveness of medications, and in some cases produce harmful side effects. The main types of drug degradation are hydrolysis, oxidation, and photodegradation. To prevent degradation, medications should be stored properly in a cool, dry place away from light and heat, expiration dates should be checked, and storage and usage instructions should be followed closely.