This document provides 30 tips and pearls related to dermatopathology. Some of the key points include: a biopsy cannot definitively prove or disprove certain diagnoses; deeper levels in a biopsy block can provide more diagnostic information; markers and genetic tests do not always indicate lymphoma; lentigo maligna often arises de novo rather than from a nevus; and dermatopathology is to dermatology as an EKG is to cardiology in terms of diagnostic assistance.

5. ACNE

6. Treatment of scarring alopecias

16. scabies

21. Leg ulcers

22. Leg ulcers

23. MICOSIS FUNGOIDES / S.SEZARY

24. 1.- Dogmatic dermpath people are either really right or really wrong. 2.- “Consistent with””suggestive of” means tha pathologist is not sure! 3.- A biopsy cannot prove a rash is a drug reaction and cannot prove that it is not a drug reaction 4.- A biopsy cannot prove that a lesion is a bug bite or i not a bug bite. 5. Eosinophils usually are NOT present in lupus erythematosus. 6.- Eosinophils in vasculitis do not prove it is drug-related. 7.- Flame figures is not specific for Well´s syndrome. 8.- Nuclear dust does not mean vascilitis necessarily. 9.- Sweet syndrome –is it a vasculitis? 10.- Lymphocytic vasculitis and perivasculitis are nebolous. 11.- Erythema annulare centrifugum. The coat-sleeve infiltrate is overrated. 12.- The best special stain in dermpath is DEEPER LEVELS in the block. 13.- T and B-cell markers on rashes are usually not hepful. 14.- Gene rearrangements studies do not prove something is lymphoma. 15.- Langerhans microgranulomas in the epidermis are common witn contact dermatitis. PEARLS IN DERMPATH

25. 16.- If it is called junctonal dysplastic nevus, but is on severely sun damaged skin, it likely is a lentigo maligno. 17.- Almost all lentigos malignas arise de novo, NOT from a nevus. 18.- Dysplastic nevus grading is a mess. 19.- Follicular actinic keratosis- reason for liquid nitrogen failure. 20.- Keratoacanthomas usually are squamous cell carcinomas. 21.- Biopsy of white macules is usually a waste of time. 22.- Biopsy of subtle plaque: biopsy the edge with normal skin for comparison. 23.- Horizontal scalp biopsies might be likely to miss lupus erythematous. 24.- Culture, serology, or other tests are better tna biopsy for some diagnoses. 25.- Biopsy cannot prove something is congenital nevus. 26.- Leishmaniasis: NNN media for culture 27.- Dermatologist are qualified to read shin biopsies. 28.- Morgellon´s disease is a new name popular on intenet for patients with delusions of parasitosis 29.- Spindle-cell malignancies on sun damaged skin. The big 3 are atypical fibroxanthoma, spindel-cel melanoma and spindle-cell squamous cell carcinoma. 30.- Dermpath is to derm as EKGs are to cardiologists, and X-rays are to orthopedists.

34. OBSESSIVE COMPULSIVE DISORDER