MRI characteristics in Relapsing- Remitting versus Secondary- Progressive MS by Till Sprenger, Department of Neurology and Division of Neuroradiology University Hospital Basel, Switzerland
MRI characteristics in Relapsing- Remitting versus Secondary- Progressive MS by Till Sprenger, Department of Neurology and Division of Neuroradiology University Hospital Basel, Switzerland
GB Syndrome is an inflammatory disease, incidence is rising sharply in Pakistan, it needs epidemiological investigation and extensive search for reason of this endemic status.
Austin Anesthesiology is an open access, peer reviewed, scholarly journal dedicated to publish articles in all areas of Anesthesia & Anesthesiology. The renowned editorial team ensures a balanced, expert assessment of the articles published with an aim to provide a forum for physicians, researchers and other healthcare professionals to find most recent advances in all areas of anesthesiology.
Austin Anesthesiology accepts original research articles, review articles and short communication covering all aspects of Anesthesia for review and possible publication.
Austin Anesthesiology strongly supports the scientific up gradation and fortification in related scientific research community by enhancing access to peer reviewed scientific literary works. Austin Publishing Group also brings universally peer reviewed journals under one roof thereby promoting knowledge sharing, mutual promotion of multidisciplinary science.
Muscular Dystrophy & Myasthenia Gravis - PPT
By Prof. Dr. R. R. Deshpande
• This PPT is based on the – Syllabus of CCIM ( 2014) for4th BAMS – Kayachikitsa subject – Paper 2 Part A Point No 5 .
• Contents of PPT are – Causes ,Symptoms & Treatment of Muscular Dystrophy & Myasthenia Gravis
• Visit – www.ayurvedicfriend.com
• Phone – 922 68 10 630
ANAESTHESIA MANAGEMENT IN PATIENTS OF NEUROMUSCULAR DISORDERS.pptxSumit Tyagi
Comprehensive ppt covering myasthenia graves in details along with other neuromuscular disorders.
brief and complete solution for presentation needs of DNB/MD students in anaesthesia department.full coverage of myasthenia graves with light on all other neuromuscular disease.illustrative diagram of NMJ.Tabular list of drugs exacerbating myasthenia graves and increasing the duration of action of the muscular relaxants
GB Syndrome is an inflammatory disease, incidence is rising sharply in Pakistan, it needs epidemiological investigation and extensive search for reason of this endemic status.
Austin Anesthesiology is an open access, peer reviewed, scholarly journal dedicated to publish articles in all areas of Anesthesia & Anesthesiology. The renowned editorial team ensures a balanced, expert assessment of the articles published with an aim to provide a forum for physicians, researchers and other healthcare professionals to find most recent advances in all areas of anesthesiology.
Austin Anesthesiology accepts original research articles, review articles and short communication covering all aspects of Anesthesia for review and possible publication.
Austin Anesthesiology strongly supports the scientific up gradation and fortification in related scientific research community by enhancing access to peer reviewed scientific literary works. Austin Publishing Group also brings universally peer reviewed journals under one roof thereby promoting knowledge sharing, mutual promotion of multidisciplinary science.
Muscular Dystrophy & Myasthenia Gravis - PPT
By Prof. Dr. R. R. Deshpande
• This PPT is based on the – Syllabus of CCIM ( 2014) for4th BAMS – Kayachikitsa subject – Paper 2 Part A Point No 5 .
• Contents of PPT are – Causes ,Symptoms & Treatment of Muscular Dystrophy & Myasthenia Gravis
• Visit – www.ayurvedicfriend.com
• Phone – 922 68 10 630
ANAESTHESIA MANAGEMENT IN PATIENTS OF NEUROMUSCULAR DISORDERS.pptxSumit Tyagi
Comprehensive ppt covering myasthenia graves in details along with other neuromuscular disorders.
brief and complete solution for presentation needs of DNB/MD students in anaesthesia department.full coverage of myasthenia graves with light on all other neuromuscular disease.illustrative diagram of NMJ.Tabular list of drugs exacerbating myasthenia graves and increasing the duration of action of the muscular relaxants
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
1. A CASE OF MULTIPLE SCLEROSIS :
Follow Up Since 1997
Dr. L. K. Malhotra
MBBS, MD, DM (Neurology)
Consultant Neurologist
New Delhi, India
2. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
BACKGROUND
• Tertiary neurocentre : 0-2 new patients of
MS/ yr
• Majority patients have no insurance cover
• Patient can consult any neurologist
throughout India anytime
3. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
• 22 yrs Female SM
• On 22/7/97 H/O Acute onset ataxia
without headache, vomiting, fever, tinnitus,
deafness
• No past H/O fever, immunization, rash,
visual loss. H/O myocarditis in childhood.
No DOE
• O/E : Fundus normal, Gait ataxia, brisk
jerks, extensor plantars
4. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
• Investigations : Haemogram, Blood sugar,
liver, renal function tests, Rheumatoid
factor, ANF, DsantiDNA Ab, Se B12 levels,
ECG, X - ray chest ---- normal
• HIV and VDRL ---- negative
• CSF : cytology : 20 cells L, Proteins : 80
mg, sugar : 40mg, oligoclonal bands
----negative
• VEP : 112 ms ----- bilateral
8. A CASE OF MULTIPLE SCLEROSIS : 17 YEARS
FOLLOW-UP
• Treatment : I.V. -- M.P. 5 g followed by
oral steroids for 2 weeks
• Clinical and radiological improvement
seen
14. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
• Oct 2000 : worsening of ataxia
• MRI brain : Fresh brain stem and supra
tentorial lesions
• Treatment : I.V. M.P. 5 g
• Partial Improvement
15. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
• Nov 2000 : started on Avonex
16. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
• Aug 2001 : Worsening of ataxia, Tremulousness
on standing, limb ataxia
• MRI brain : fresh lesion in medulla
• Treatment : I.V. M.P. 3 g, Azathioprine added.
• Partial improvement
20. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
• April 2003 : worsening of symptoms. Oral
steroids for 3 weeks minimal improvement
• July 2003 : worsening of symptoms. Oral
steroids started. No improvement.
• MRI Brain : fresh parasaggital lesion
• MRI cervical and dorsal spine : sub acute
to chronic plaque seen.
• I.V. M.P. 3 g, no improvement
25. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
• Aug 2003 : dysarthric, gaze evoked
nystagmus, limb and gait ataxia, ankle
clonus, brisk jerks, extensor plantars
• Needed support to walk.
• RRMS SPMS
26. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
SUMMARY
• 22 yrs Female
• 7 / 1997 : First attack --- I.V. M.P.
• 10/2000 : Second attack --- I.V. M.P.
• 11/2000 : Avonex started
• Relapses : Aug 2001, Sep 2002, Apr 2003,
Jul 2003 Progressive course
• Aggressive Disease since Sep 2002
27. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
Treatment options :
• Mitoxantrone
• Cyclophosphamide
• I.V. MethylPrednisolone monthly
• I.V. Immunoglobulins
• G.A.
• Injection Rebif
28. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
Pulse therapy
• I.V. cyclophosphamide with I.V. high dose steroids
• Cyclophosphamide 1000 mg/m2 /course
(approx. 1500-2000 mg for average person)
• I.V. Methylprednisolone 750 mg BD or
Dexamethasone 150 mg BD
• Monitor blood counts, urine, X-ray chest, ECG
• Anti – emetics before cyclophosphamide
• Hydration I.V. / oral
29. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
PULSE THERAPY
1. 27 Oct 2003 --------- 6 weeks
2. 08 Dec 2003 --------- 6 weeks
3. 13 Jan 2004 --------- 6 weeks
4. 03 Mar 2004 --------- 2 months
5. 05 May 2004 --------- 2 months
6. 06 Jul 2004 --------- 4 months
7. 13 Nov 2004
30. A CASE OF MULTIPLE SCLEROSIS : Follow Up
Since 1997
• No urinary / menstrual problem. Mild
alopecia.
• Injection Rebif 22 microgm thrice a week
since Nov 2004 till now.
• And no relapse since then.
