IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Embryo implantation in the region of a previous caesarean section scar is a rare but potentially catastrophic complication of a previous cesarean birth.
Embryo implantation in the region of a previous caesarean section scar is a rare but potentially catastrophic complication of a previous cesarean birth.
Fetal anterior neck teratomas are tumors which arise from the
three blastomericl ayers - ectoderm, endoderm and mesoderm. It occurs when the totipotent germ cells are out of control of primary organizers [1,2]. Th e histologic features may include cystic and solid areas with organoid patterns and it may include mature or immature cells [1]. Even though the most common area of occurrence is at sacrococcgeal area it can also occur in other body parts [1,3]. In this case report we presented one of the rare place of teratoma - anterior fetal neck teratoma.
Subserosal leiomyomas rarely have any significant effect on a pregnant uterus, but very large ones may compress the uterine cavity in early pregnancy resulting in abortion. A 32 year old female presented with vagina bleeding for days. There was a 3 month history of amenorrhoea. Her last confinement was 3 years prior to presentation which ended with vaginal delivery with no complication. However, obstetric ultrasound scan done 3 years earlier during the first pregnancy showed a subserous leiomyoma at the fundus of the uterus. On examination, the uterine size was greater than the gestational age. Abdomino-pelvic ultrasound showed huge degenerating leiomyoma extending from the uterine fundus to the left lobe of the liver. The uterus was anteverted and harbours a 12 week non-viable foetus which appeared compressed in the upper aspect of the uterine cavity. The size of the myometrium was normal for the gestational age. An impression of missed abortion associated with a huge degenerating subserous leiomyoma was made.
In this presentation we will focus on aetiological factors that cause infirtility. Our focus is on US depiction of these aetiological factors to help physician in the management of infirtility.
We have nothing to do with direct radiological intervention in the management of infirtility in this presentation.
Natural history of caesarean scar pregnancy on prenatal ultrasound the cross...Võ Tá Sơn
Natural history of caesarean scar pregnancy on prenatal ultrasound the cross-over sign Cali 2016
Dấu hiệu cross-over trong siêu âm tiền sản tiên lượng tiến triển của thai ở sẹo mổ lấy thai, võ tá sơn
Endometriosis is known to have a remarkably negative effect on the Quality of Life of the women. Surgery is considered when medical therapy is unsuccessful or in the setting of infertility. A high recurrence rate is reported in advanced stages of endometriosis. Thus, Complete excision and prevention of recurrence is particularly important.
Adnexal masses are commonly identified in pregnancy but they are rarely malignant. Most adnexal masses either resolve spontaneously or can be managed conservatively during pregnancy. Pregnancy may alter the serum levels of tumour markers, making the interpretation of results difficult.
Fetal anterior neck teratomas are tumors which arise from the
three blastomericl ayers - ectoderm, endoderm and mesoderm. It occurs when the totipotent germ cells are out of control of primary organizers [1,2]. Th e histologic features may include cystic and solid areas with organoid patterns and it may include mature or immature cells [1]. Even though the most common area of occurrence is at sacrococcgeal area it can also occur in other body parts [1,3]. In this case report we presented one of the rare place of teratoma - anterior fetal neck teratoma.
Subserosal leiomyomas rarely have any significant effect on a pregnant uterus, but very large ones may compress the uterine cavity in early pregnancy resulting in abortion. A 32 year old female presented with vagina bleeding for days. There was a 3 month history of amenorrhoea. Her last confinement was 3 years prior to presentation which ended with vaginal delivery with no complication. However, obstetric ultrasound scan done 3 years earlier during the first pregnancy showed a subserous leiomyoma at the fundus of the uterus. On examination, the uterine size was greater than the gestational age. Abdomino-pelvic ultrasound showed huge degenerating leiomyoma extending from the uterine fundus to the left lobe of the liver. The uterus was anteverted and harbours a 12 week non-viable foetus which appeared compressed in the upper aspect of the uterine cavity. The size of the myometrium was normal for the gestational age. An impression of missed abortion associated with a huge degenerating subserous leiomyoma was made.
In this presentation we will focus on aetiological factors that cause infirtility. Our focus is on US depiction of these aetiological factors to help physician in the management of infirtility.
We have nothing to do with direct radiological intervention in the management of infirtility in this presentation.
Natural history of caesarean scar pregnancy on prenatal ultrasound the cross...Võ Tá Sơn
Natural history of caesarean scar pregnancy on prenatal ultrasound the cross-over sign Cali 2016
Dấu hiệu cross-over trong siêu âm tiền sản tiên lượng tiến triển của thai ở sẹo mổ lấy thai, võ tá sơn
Endometriosis is known to have a remarkably negative effect on the Quality of Life of the women. Surgery is considered when medical therapy is unsuccessful or in the setting of infertility. A high recurrence rate is reported in advanced stages of endometriosis. Thus, Complete excision and prevention of recurrence is particularly important.
Adnexal masses are commonly identified in pregnancy but they are rarely malignant. Most adnexal masses either resolve spontaneously or can be managed conservatively during pregnancy. Pregnancy may alter the serum levels of tumour markers, making the interpretation of results difficult.
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
— Pregnancy in non-communicating rudimentary horn is very rare and life threatening. It is often not diagnosed unless it terminates by rupture in the second trimester. Prerupture diagnosis of rudimentary horn pregnancy with USG is technically difficult, with sensitivity of 30%. Here a case of unruptured ectopic pregnancy in non-communicating rudimentary horn of unicornuate uterus at 15 weeks of gestation is presented. This patient presented in emergency department as a case of intrauterine fetal death. Laparotomy was carried out and excision of rudimentary horn was done.
A case report of cervical ectopic pregnancy misdiagnosed as cervical miscarriageApollo Hospitals
Cervical pregnancy is a rare variety of ectopic gestation. The aetiology is obscure. Diagnosis may be difficult unless the clinician/the radiologist is conscious of the entity. The evaluation of first trimester vaginal bleeding or pelvic pain is an important task for the emergency physician. The early identification of an ectopic pregnancy can help prevent significant morbidity and mortality for patients seeking emergency care. We present the case of a patient found to have a cervical ectopic pregnancy.
Abstract
This case report describes the diagnosis and management of a large mesenteric cyst in a 55 year old lady who presented with abdominal distension & with mass in the left upper quadrant. Mesenteric cysts are rare, benign, abdominal tumors to which <1000 cases have been reported in the literature. While 40% of cases are incidental findings found either through physical examination or imaging, they can cause non-specific abdominal symptoms including pain, altered bowel habits, nausea/vomiting or anorexia. Less commonly, 10% of cases can present with bowel obstruction, volvulus, torsion or shock. In general, the lack of characteristic clinical and radiological features presents as a diagnostic difficulty.
The mainstay in imaging is computerized tomography (CT). CT identifies and helps aid the decision to pursue a laparoscopic or open laparotomy approach, where complete surgical resection is the ultimate goal. In our patient a CT Abdomen & Pelvis showed a large, loculated cystic mass measuring 30cm in cranio-caudal length and 16cm in the transverse and anterior/posterior diameter. While different approaches have been described in the literature to surgically resect such cysts, our approach was largely reflective of size and adherence to surrounding structures in this case. A laparotomy was performed using an upper mid-line 7 cm incision; 4500cc of fluid was aspirated from the cyst which was found to originate from the small bowel mesentery. A complete resection of the multi-loculated cystic sac was done that included the resection of the middle mesenteric vein. The post-operative period was uneventful. The patient was discharged on post-operative day 2. The Histopathology identified the mass as a multi-loculated peritoneal inclusion-type cyst.
Adrenal Mass in Pregnancy: Diagnostic Approach and DilemmasApollo Hospitals
An adrenal incidentaloma is a mass lesion greater than 1 cm in diameter, incidentally found during radiologic examination for other reasons.
1. Such “adrenal incidentalomas” are increasingly recognised in clinical practice.
2. This is attributed to routine use of sophisticated and sensitive imaging techniques, with a reported prevalence of 4.4%.
3. Incidental findings of such masses pose dilemmas in evaluation and management, as current recommendations based on expert opinion.
4. Are open to debate in terms of cost and clinical
benefits. The uncertainties in management multiply with
such adrenal incidentalomas in the context of pregnancy.
We report a rare case of a large adrenal incidentaloma
complicating second trimester of pregnancy. This case
outlines the huge decisional dilemmas, both for the patient
and healthcare provider.
Vesicouterine Fistula Following Cesarean Delivery – Ultrasound Diagnosis and ...Michelle Fynes
Vesicouterine fistulae are uncommon, with most units reporting 1–5 cases over 5–15 year periods. To date there has been a paucity of case reports regarding this problem and only a few case series. In this report we outline the presentation and management of a vesicouterine fistula complicating a repeat Cesarean delivery, specifically describing the role of transvaginal ultrasound.
Spontaneous rupture of endometriotic cyst in 3rd trimester of pregnancyApollo Hospitals
Endometriosis is a well established cause of female infertility and may be associated with early pregnancy losses. Association of endometriosis with pregnancy is rare. Ruptured endometriotic cyst presenting as acute abdomen in pregnancy is even a rarer presentation.
We present hereby a rare and interesting case, presented in our hospital, of Spontaneous rupture of endometiotic Cyst in 3rd trimester of pregnancy and its subsequent management.
Similar to A Case of Abdominal Pregnancy, Primary vs Secondary – Radiological Workup (15)
An Examination of Effectuation Dimension as Financing Practice of Small and M...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Does Goods and Services Tax (GST) Leads to Indian Economic Development?iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Childhood Factors that influence success in later lifeiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Emotional Intelligence and Work Performance Relationship: A Study on Sales Pe...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Customer’s Acceptance of Internet Banking in Dubaiiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
A Study of Employee Satisfaction relating to Job Security & Working Hours amo...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Consumer Perspectives on Brand Preference: A Choice Based Model Approachiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Student`S Approach towards Social Network Sitesiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Broadcast Management in Nigeria: The systems approach as an imperativeiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
A Study on Retailer’s Perception on Soya Products with Special Reference to T...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
A Study Factors Influence on Organisation Citizenship Behaviour in Corporate ...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Consumers’ Behaviour on Sony Xperia: A Case Study on Bangladeshiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Design of a Balanced Scorecard on Nonprofit Organizations (Study on Yayasan P...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Public Sector Reforms and Outsourcing Services in Nigeria: An Empirical Evalu...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Media Innovations and its Impact on Brand awareness & Considerationiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Customer experience in supermarkets and hypermarkets – A comparative studyiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Social Media and Small Businesses: A Combinational Strategic Approach under t...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Secretarial Performance and the Gender Question (A Study of Selected Tertiary...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Implementation of Quality Management principles at Zimbabwe Open University (...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Organizational Conflicts Management In Selected Organizaions In Lagos State, ...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdf
A Case of Abdominal Pregnancy, Primary vs Secondary – Radiological Workup
1. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 14, Issue 12 Ver. III (Dec. 2015), PP 43-47
www.iosrjournals.org
DOI: 10.9790/0853-141234347 www.iosrjournals.org 43 | Page
A Case of Abdominal Pregnancy, Primary vs Secondary –
Radiological Workup
Dr. Mohd Kamran Siddiqui, Dr. Pramod Setty J.,Dr. Bhagyavathi M. Kulkarni,
Dr. Jeevika M.U., Dr. Sindu P. Gowdar.
I. Introduction
Ectopic pregnancy was first recognised by Busiere in 1663 on examining the body of an executed
prisoner in Paris. Gifford made a more complete report in 1731 in England, describing the condition in which
the fertilised ovum was implanted anywhere outside the uterine cavity [1]. During this decade the number of
hospitalisations for ectopic pregnancy has tripled and ectopic pregnancy has emerged as a leading cause of
maternal morbidity[2,3]. Fortunately the risk of death has declined despite increasing incidence of the disease.
The incidence of ectopic pregnancy in non-white patients is approx. 12/1000. Out of all ectopic pregnancies,
98.5% are singleton tubal pregnancies and rest is at other sites, which create diagnostic problems and have been
associated with greater morbidity and mortality than tubal pregnancies. Pregnancy in the rudimentary horn of a
bicornuate uterus is a very rare condition and Johnsen reported the incidence of this pregnancy at approximately
one in one lakh pregnancies[4].
Abdominal pregnancy, with a diagnosis of one per 10000 births, is an extremely rare and serious form
of extrauterine gestation [5]. Abdominal pregnancy is classified as primary or secondary. The diagnosis of
primary abdominal pregnancy was confirmed according to Studdiford’s criteria [6]. In these criteria, the
diagnosis of primary abdominal pregnancy is based on the following anatomic conditions: 1) normal tubes and
ovaries, 2) absence of an uteroplacental fistula, and 3) attachment exclusively to a peritoneal surface early
enough in gestation to eliminate the likelihood of secondary implantation. The placenta sits on the
intraabdominal organs generally the bowel or mesentery, or the peritoneum, and has sufficient blood supply.
Sonography is considered the front-line diagnostic imaging method, with magnetic resonance imaging (MRI)
serving as an adjunct in cases when sonography is equivocal and in cases when the delineation of anatomic
relationships may alter the surgical approach [7].
Mullerian duct anomalies result from defective fusion, canalization or absorption of the median septum
of the female reproductive system during embryonic development [8]. A working classification depending on
the degree of failure of normal development was proposed by Buttram and Gibbons in 1979 and modified in
1988 by American Society of Reproductive Medicine[8]. The prevalence of uterine malformation is estimated to
be 6.7% in the general population, slightly higher (7.3%) in the infertility population, and significantly higher in
a population of women with a history of recurrent miscarriages (16%) [9]. Presence of bicornuate uterus
predisposes to lower fertility, high risk of abortions, preterm births. IUGR, malpresentations and lower fetal
survival rate. However after corrective surgery successful pregnancy with good outcome is achieved in 80% of
cases [8]. Ruptured horn poses a life threatening situation to the pregnant woman.
MRI is accepted as a highly accurate tool for the evaluation of müllerian duct anomalies [10-15] and
thus is commonly used in clinical practice. In clinical practice, the results of theMRI examination are used by
the clinician inthe context of a comprehensive clinical assessmentscheme to reach the final clinical diagnosis.
Information obtained from pelvic examination, laparoscopy, office hysteroscopy, or other imaging examinations
such as sonography, sonohysterography, and hysterosalpingography differs from the type of information
provided by MRI, but these imaging techniques provide added information that complements the information
gained from MRI.
Here we present an interesting radiological workup of a case of 20 year old woman with abdominal pregnancy.
II. Case Report
A 20 year old P1L1 female who presented to our emergency medicine department with severe anaemia
associated with generalised weakness, abdominal distension and fatigue for evaluation. The patient gives a
history of 4months of amennorhoea. She gives a past history of previous full term normal delivery. She was
referred to the Radiology department for abdominal sonography.
Ultrasound revealed a dead fetus of about 17weeks gestation seen in the right iliac fossa. The uterus
was found intact with thick endometrium. Bilateral tubes and ovaries were separately identified. The placenta
however could not be localised, instead a vague heterogenous mass was localized in left iliac fossa displacing
the sigmoid colon to the right side, which was considered as placenta probably attaching to mesentery. There
2. A Case of Abdominal Pregnancy, Primary vs Secondary – Radiological Workup
DOI: 10.9790/0853-141234047 www.iosrjournals.org 44 | Page
was moderate intraperitoneal free fluid collection. A diagnosis of primary abdominal pregnancy was made out
based on the studdiford’s criteria.
MRI of abdomen was done for localisation and evaluation of attachment of placenta . It revealed a
bicornuate uterus with ruptured left horn. Fetus of around 17weeks was identified towards the right of maternal
spine. The placenta was seen attached to the sigmoid colon mesentery with large proportion resting on the
ruptured horn, pushing the bowel loops towards the right side. The final diagnosis was secondary abdominal
pregnancy following rupture of left horn of bicornuate uterus with foetal demise.
The patient underwent emergency explorative laparotomy. The rudimentary left horn of uterus was
removed and sent for histopathological analysis. Bilateral tubes and ovaries were found intact on surgical table.
The histopathological examination revealed placental elements within the rudimentary horn confirming the
diagnosis of secondary abdominal pregnancy.
The postoperative period was uneventful. Regular follow up was done with no further complications.
(1) (2)
Figure 1. Axial ultrasonogram image in the region of left lower abdomen demonstrates vague abdominal mass
with echogenicity similar to placenta, attached to the abdominal wall anteriorly, displacing bowel loops
surrounding it.
Figure 2. Sagittal ultrasonogram image demonstrates normal uterus with endometrium and dead foetus in the
peritoneal cavity lying above it.
Figure 3. T2 weighted SPAIR axial MRI image at the level of lower abdomen demonstrates normal cornu of
uterus on right side and heterogeneous placenta with internal haemorrhage appearing dark with hyper intense
areas within on left side, attached to the ruptured left horn and sigmoid mesentery. Peritoneal collection also
noted.
3. A Case of Abdominal Pregnancy, Primary vs Secondary – Radiological Workup
DOI: 10.9790/0853-141234047 www.iosrjournals.org 45 | Page
(4) (5)
Figure 4. Coronal T2W image clearly demonstrates the foetus lying in the peritoneal cavitywith fluid
surrounding it and mass consisting of placenta and ruptured left horn on left side which appears heterogeneous
containing areas of haemorrhage appearing hyper intense in centre.
Figure 5. T2W sagittal image showing the dead foetus in the peritoneal cavity on the right side.
Figure 6. Gross specimen of foetus, left ruptured horn and placenta
Figure 1. Histopathological analysis correlated well with imaging findings and demonstrated smooth muscle
infiltrated by mixed inflammatory cell infiltrates and eosinophilic fibrin material. Chorionic villi are seen
adherent directly to the smooth muscle bundles and at place seen invading it.
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III. Discussion
Abdominal pregnancy refers to a pregnancy that has implanted within the peritoneal cavity, external to
the uterine cavity and fallopian tubes. Bicornuate uterus results from non-fusion of the two cornua of the uterus.
Estimated incidence of pregnancy in rudimentary horn is 1 in 10000 to 1 in 40000 [16].Most likely mechanism
of a pregnancy in a non-communicating rudimentary horn is transperitoneal migration of the spermatozoa or the
fertilized ovum [17]. Depending on the ability of the horn to undergo hypertrophy and its musculature the
rupture occurs between 5 weeks to 35 weeks. 80% of rupture occurs before 20 weeks. The haemorrhage
occurring because of rupture is massive and life threatening if corrective measures are not taken immediately.
The usual outcome of rupture in second trimester in 90% of cases is fetal demise. A routine USG examination in
suspected cases of uterine anomaly or an MRI is also appropriate to prevent the catastrophe.
The classic abdominal pregnancy ultrasound findings of an empty uterine cavity with absence of
myometrial tissue between the maternal urinary bladder and the pregnancy becomes more obvious on the larger
FOV of CT or MRI [18]. MRI and CT can be helpful in confirming the diagnosis, determining anatomic
relationships and potential vascular connections, and assessing placental adherence. On MRI, a gestational
saclike structure associated with hematoma may, for example, be depicted in the pouch of Douglas.
Enhancement of the peritoneum around the saclike structure may also be seen in abdominal pregnancies [19].
Attempted removal of a placenta that is adherent to abdominal organs can result in fatal hemorrhage. MRI is
useful in the accurate localization of the placenta, detection of arterial feeders, and assessment of placental
adherence to surrounding organs [20]. On CT, an intraabdominal extrauterine gestational saclike structure with
an enhancing rim can be seen; however, CT generally provides a less detailed placental evaluation.
In the present case, we were able to demonstrate primary abdominal pregnancy according to
Studdiford’s criteria with the use of transvaginal and transabdominal ultrasound examination. We found both
fallopian tubes and ovaries intact. With regard to the second criterion, we did not observe any uteroplacental
fistulae in our case. Since abdominal pregnancy at less than 20 weeks of gestation is considered early [21], our
case was regarded as early, and so we dismissed the possibility of secondary implantation.
Ultrasound examination is the usual diagnostic procedure of choice, but the findings are sometimes
questionable. They are dependent on the examiner’s experience and the quality of the ultrasound. Transvaginal
ultrasound is superior to transabdominal ultrasound in the evaluation of ectopic pregnancy since it allows a
better view of the adnexa and uterine cavity. MRI may help in surgical planning by evaluating the extent of
mesenteric and uterine involvement [22]. Non-contrast MRI using T2-weighted imaging is a sensitive, specific,
and accurate method for evaluating ectopic pregnancy [23], and we used it in our case.
Our patient had never taken antenatal visits and hence was unknown of her condition. We were able to
demonstrate the abdominal pregnancy through ultrasonography but missed the bicornuate uterus and ruptured
horn which was only possible through MRI.
IV. Conclusion
With the advancements made in radio-diagnosis it is possible to detect the Mullerian anomaly even in
pregnancy. However the possibilities of missing them are higher in inexperienced hands. In absence of timely
diagnosis or misdiagnosis the condition can be fatal. Although CT and MRI are not commonly used in the
imaging of patients with a positive β-HCG test, various types of ectopic pregnancy are occasionally imaged with
these modalities. There are certain CT and MRI features that may aid in the diagnosis of ectopicpregnancy, most
of which are correlates ofthe classic sonographic imaging signs of thiscondition. Moreover, MRI may be a
useful adjunctto ultrasound in the diagnosis and evaluationof various types of ectopic pregnancy as well as
mullerian duct anamolies and complications when question still persists after ultrasonography or diagnosis is
critical in patient’s evaluation.
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