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A 65-year-old alcoholic was taken to the emergency room with severe necrotic, blackened areas
on both feet and several draining ulcers on his heels and toes. He was stuporous. His medical
records indicated no vaccination history in the past 20 years. During that evening he had a
seizure and was treated with phenytoin and barbiturates. By the end of the night he had
developed increasing rigor and respiratory distress and was unresponsive. His neck was stiff and
hvperextended and his teeth clenched in a grimace. Culture from the ulcers revealed gram
positive bacilli that were terminal endospore formers. Specific therapy and supportive care led to
his full recovery. 1. What organism is causing this disease? Name of Disease? What led you to
this conclusion? Signs and Symptoms (What is the unusual ghostly smile-like facial expression
called)? 2. Route of infection? Method of Transmission? Portal of entry? Natural Reservoir and
Source? 3. What virulence factor/toxins does it produce? What are their effects? Be specific.
What specific therapy is used to treat this infection? Can it be prevented? 4. Copy-paste the
websites for sources you used for all three cases. Full credit is given for at least

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  • 1. A 65-year-old alcoholic was taken to the emergency room with severe necrotic, blackened areas on both feet and several draining ulcers on his heels and toes. He was stuporous. His medical records indicated no vaccination history in the past 20 years. During that evening he had a seizure and was treated with phenytoin and barbiturates. By the end of the night he had developed increasing rigor and respiratory distress and was unresponsive. His neck was stiff and hvperextended and his teeth clenched in a grimace. Culture from the ulcers revealed gram positive bacilli that were terminal endospore formers. Specific therapy and supportive care led to his full recovery. 1. What organism is causing this disease? Name of Disease? What led you to this conclusion? Signs and Symptoms (What is the unusual ghostly smile-like facial expression called)? 2. Route of infection? Method of Transmission? Portal of entry? Natural Reservoir and Source? 3. What virulence factor/toxins does it produce? What are their effects? Be specific. What specific therapy is used to treat this infection? Can it be prevented? 4. Copy-paste the websites for sources you used for all three cases. Full credit is given for at least