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to Get the Most
from Your NIH Application




  Brought to you by Principal Investigators Association
             www.principalinvestigators.org
                   Phone: 1-800-303-0129
           Email: info@principalinvestigators.org
Principal Investigators Association offers a free eNewsletter, bi-weekly e-Alerts,
grant application manuals, executive reports and a year-long series of online
seminars — all devoted to helping you improve performance and spend
more time doing what you love: the research.

Our goal as an organization is to be the world’s leading source of real-world,
results-oriented information for our members in all fields of science. Our
unique approach — delivering targeted guidance, case studies, success
strategies and best practices — has earned us a reputation for depth,
usefulness and high-value information as well as a loyal group of members who
rely on that information to help them with their administrative and funding
duties.

We invite you to review all of our products and services at
www.principalinvestigators.org.


       © 2010 Principal Investigators Association and Karin Rodland. The entire contents of this publication are protected by
      Copyright, worldwide. All rights reserved. Reproduction or further distribution by any means, beyond the paid customer,
      is strictly forbidden without written consent of Principal Investigators Association, including photocopying and digital,
      electronic, and/or Web distribution, dissemination, storage, or retrieval. This report is an independent publication by
      Principal Investigators Association and Karin Rodland. It is not endorsed nor has any official connection with Pacific
      Northwest National Laboratory Department of Energy, National Institutes of Health, or any other entity.
Pretend that you’ve got an hour to
address an advanced biology class
atPretendexcellentanhigh address an advanced
     an that you’ve got hour to school or an
  biology class at an excellent high school or an especially
especiallycollege freshmen. What would you tell them
  bright group of bright group of college
freshmen. What research, its impact, and why they
  to give the flavor of your would you tell them
to give excited? flavor of your research,
  should get the
its impact, and why they should get
excited?
Don’t be obsessed with showing off how much
you know, and don’t go into great experimental
detail or include a lot of background on the
history of your field.
Take the long view of “impact.”
Reviewers want to know how the research you’re doing
will change the field and translate into an impact in
human health. So if you’re doing a basic study of, say,
DNA repair enzymes, you need to say, “Even though this is
basic research, it’s needed for new drug development.
Think that far ahead.
Tell reviewers the ultimate utility of your research — even
if it’s five years down the road.
Make your train of thought crystal
clear. You know the logical
connections in your head. You know
why you’re doing a specific
experiment.

Don’t forget to tell the reviewers.


Some of what they’re evaluating is your
thought process — your summary of
the significance of your research and
your summary of its impact.
Introducing Science Pro Insider
                        The only Free Monthly eNewsletter
                        focused on providing best practices on
                        obtaining grant funding, lab management,
                        career advice and much more!

                      SUBSCRIBE TODAY!
                      Visit http://bit.ly/SciencePro


 Inside November’s Issue:
 •   Communicating Data-Rich Results – Key Success Factors
 •   How to Leverage Connections for Private Funding
 •   R01 or R21? Choose The Appropriate Grant Type
 •   Dealing with the ‘Negative’ Staffer in your Lab
Don’t use words you don’t need.

          A 12-page form, as opposed to a 25-
          page form, means there’s a great deal
          of pressure on you to show your
          thought processes in a direct and
          architectural way.

          Show that you know what’s
          important and what’s superfluous.


             Chlorine
                           Argon      Platinum
      Nitrogen
                  Fluorine                                 Gallium
Lithium
                                 Manganese       Hassium
                           Potassium
                      Sulfur
             Praseodymium
                               Vanadium
Get a complete draft done at least
10 days before it’s due and find
someone who’s not involved in the
project — don’t use a post-doc in
your lab — to check it out.

That person can find the logical
holes and can help you outline the
impact.
Use the word “impact” as needed.
It shows you paid attention
to the new criteria for grants.
End your grant with a paragraph that says what the
         government gets at the end of the day if it funds your
         research.

That’s exactly what “impact” is.

The difference between significance and impact is, basically, that
significance is whether what you’re doing is worth doing and
impact is what the NIH gets after it’s funded you. You can be
explicit: “At the conclusion of this research program, we will have
identified [fill in the blank] and we will have determined [fill in the
blank] and we will be on our way to developing [fill in the blank].


That’s impact.
NIH R01 Grant Application Mentor:
                                   An Educational How-to Manual

                                                • 299 Pages – 8 Unique Sections – Covering each
                                                  important facet of the NIH R01 process
                                                • A 50 min. recording “Crafting Your R01 Proposal
                                                  Like the Pro’s: 10 Insider Tips Revealed”
                                                • How-to Advice from veteran grant winners
                                                • Insights, techniques and checklists to help you
                                                  write more effectively and with confidence
                                                • BONUS! Includes sample language from funded
                                                  applications


Although I have served as an NIH grant reviewer for                    For More Information
more than 20 years, the R01 Grant Application Mentor                   http://bit.ly/R01Grant
has significantly enhanced my efforts as a reviewer and
in the preparation of my own R01 grant this year.
- Dr. Joseph C. Hall, Professor Norfolk State University

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9 Tips to Get the Most From Your NIH Application

  • 1. to Get the Most from Your NIH Application Brought to you by Principal Investigators Association www.principalinvestigators.org Phone: 1-800-303-0129 Email: info@principalinvestigators.org
  • 2. Principal Investigators Association offers a free eNewsletter, bi-weekly e-Alerts, grant application manuals, executive reports and a year-long series of online seminars — all devoted to helping you improve performance and spend more time doing what you love: the research. Our goal as an organization is to be the world’s leading source of real-world, results-oriented information for our members in all fields of science. Our unique approach — delivering targeted guidance, case studies, success strategies and best practices — has earned us a reputation for depth, usefulness and high-value information as well as a loyal group of members who rely on that information to help them with their administrative and funding duties. We invite you to review all of our products and services at www.principalinvestigators.org. © 2010 Principal Investigators Association and Karin Rodland. The entire contents of this publication are protected by Copyright, worldwide. All rights reserved. Reproduction or further distribution by any means, beyond the paid customer, is strictly forbidden without written consent of Principal Investigators Association, including photocopying and digital, electronic, and/or Web distribution, dissemination, storage, or retrieval. This report is an independent publication by Principal Investigators Association and Karin Rodland. It is not endorsed nor has any official connection with Pacific Northwest National Laboratory Department of Energy, National Institutes of Health, or any other entity.
  • 3.
  • 4. Pretend that you’ve got an hour to address an advanced biology class atPretendexcellentanhigh address an advanced an that you’ve got hour to school or an biology class at an excellent high school or an especially especiallycollege freshmen. What would you tell them bright group of bright group of college freshmen. What research, its impact, and why they to give the flavor of your would you tell them to give excited? flavor of your research, should get the its impact, and why they should get excited?
  • 5. Don’t be obsessed with showing off how much you know, and don’t go into great experimental detail or include a lot of background on the history of your field.
  • 6. Take the long view of “impact.” Reviewers want to know how the research you’re doing will change the field and translate into an impact in human health. So if you’re doing a basic study of, say, DNA repair enzymes, you need to say, “Even though this is basic research, it’s needed for new drug development. Think that far ahead. Tell reviewers the ultimate utility of your research — even if it’s five years down the road.
  • 7. Make your train of thought crystal clear. You know the logical connections in your head. You know why you’re doing a specific experiment. Don’t forget to tell the reviewers. Some of what they’re evaluating is your thought process — your summary of the significance of your research and your summary of its impact.
  • 8. Introducing Science Pro Insider The only Free Monthly eNewsletter focused on providing best practices on obtaining grant funding, lab management, career advice and much more! SUBSCRIBE TODAY! Visit http://bit.ly/SciencePro Inside November’s Issue: • Communicating Data-Rich Results – Key Success Factors • How to Leverage Connections for Private Funding • R01 or R21? Choose The Appropriate Grant Type • Dealing with the ‘Negative’ Staffer in your Lab
  • 9. Don’t use words you don’t need. A 12-page form, as opposed to a 25- page form, means there’s a great deal of pressure on you to show your thought processes in a direct and architectural way. Show that you know what’s important and what’s superfluous. Chlorine Argon Platinum Nitrogen Fluorine Gallium Lithium Manganese Hassium Potassium Sulfur Praseodymium Vanadium
  • 10. Get a complete draft done at least 10 days before it’s due and find someone who’s not involved in the project — don’t use a post-doc in your lab — to check it out. That person can find the logical holes and can help you outline the impact.
  • 11. Use the word “impact” as needed. It shows you paid attention to the new criteria for grants.
  • 12. End your grant with a paragraph that says what the government gets at the end of the day if it funds your research. That’s exactly what “impact” is. The difference between significance and impact is, basically, that significance is whether what you’re doing is worth doing and impact is what the NIH gets after it’s funded you. You can be explicit: “At the conclusion of this research program, we will have identified [fill in the blank] and we will have determined [fill in the blank] and we will be on our way to developing [fill in the blank]. That’s impact.
  • 13. NIH R01 Grant Application Mentor: An Educational How-to Manual • 299 Pages – 8 Unique Sections – Covering each important facet of the NIH R01 process • A 50 min. recording “Crafting Your R01 Proposal Like the Pro’s: 10 Insider Tips Revealed” • How-to Advice from veteran grant winners • Insights, techniques and checklists to help you write more effectively and with confidence • BONUS! Includes sample language from funded applications Although I have served as an NIH grant reviewer for For More Information more than 20 years, the R01 Grant Application Mentor http://bit.ly/R01Grant has significantly enhanced my efforts as a reviewer and in the preparation of my own R01 grant this year. - Dr. Joseph C. Hall, Professor Norfolk State University