Program Project, or P01, grants support multifaceted, long-term research programs with a major objective or theme. Program Project Grants involve the organized efforts of relatively large groups, often from multiple disciplines, wishing to collaborate by bringing together their know-how and resources. P01s are designed to meet the needs of projects whose end goal could not be achieved by investigators working independently. Additionally, the interactions and/or core facilities made possible by the P01 strengthen the individual projects of each of the members.
Getting the seal of approval from reviewers for a P01 project requires a strong leader and masterful organization, among other key elements. To succeed, you must convince reviewers of the synergy and added value resulting from this type of collaboration. Integration of all the moving parts into the whole takes time, careful planning and unparalleled management skills.
During this partnership-driven Webinar, your expert presenter will go over the basic structure of P01s, the importance of reading and following the directions, the strong focus on management, and the justification for cores for the P01. Selection and integration of the projects will be covered as will how to emphasize the synergy of the work to be done.
5 Key Take-Aways:
1. Basic structure of P01 applications
2. Management that sells the proposal
3. How to get people in the program to work together so that the plan can be integrated
4. How to justify the need for certain cores
5. How to find the right niche for a P01
P01 Grant Proposal From A to Z: Overcoming Organizational Challenges, Inspiring Reviewers
1. Presented by Dorothy E Lewis PhD
Brought to you by Principal Investigators Association
2.
3. Investigator initiated with a theme
Largely unsolicited—in some cases solicited
Involves multiple projects/multiple cores
Focused on synergy and cost saving—i.e. bang for
the buck
LOTS OF WORK/TIME to PREPARE!!!!
4. Must make compelling case that theme of
the P01 is important
The projects must EACH be important to do
and synergize—the big goal in the P01
would NOT be accomplished without
working together
YOU are the group to do the work
5. Above all, they take organization
Must herd cats—so it’s not easy—deadlines
loom.
Many make a big mistake by not
understanding what it takes to organize the
P01 properly
6. To Order Online Click Here
Or Call 1-800-303-0129 ext. 506
To Learn More Click Here
About Your Speaker
Dr. Dorothy Lewis, Professor, Internal
Medicine, Infectious Diseases at the
University of Texas Health Science Center
has a 25-year history of writing grant
applications, including P01 applications.
Her successful track record for winning
grants has given her a valuable “in the
trenches” perspective that can benefit
you, at whichever stage you find yourself.
What You Get:
1. Invite your colleagues to listen in
with you – unlimited listeners
allowed in the same viewing room
2. A FREE recording of the webinar in
CD-ROM, MP4 or PDF Transcript
3. Expert answers to your tough
questions
4. LIVE Question & Answer Session
To Order Online Click Here
Or Call 1-800-303-0129 ext. 506
7.
8. It is hard to come up with a program project
grant at the last minute or by gluing projects
together.
Best/only way is to get a group together, usually
a single person or several people have a vision
so they invite investigators who might fit with
the theme.
When the meetings are done, some projects
will be in, others out.
9.
10. Is critical
Knows how to select projects that fit together
Can negotiate conflict and resolve differences
After the meetings and a way forward is
decided, the PI must be able to include those
who fit and exclude those that don’t—done
with a smile, not animosity
11.
12. A good P01 application could be years in the making
Need to have a critical mass of investigators
Need a crucial research area
NIH has interest in the topic
Meetings to discuss and decide
More meetings
Individual projects vetted/revised
Iterative
13. Themes should be cutting edge—based on the
latest advances/technologies.
There must be expertise amongst the P01
members.
It must be apparent that the group has or will
work together well.
So the sum of the P01 is greater than the parts.
14. After some direction is determined—continue
with regular meetings of the group.
Know when the deadline is and set internal
deadlines
The PI must have all the parts together way
before (weeks before) the submission
deadline, so individual project and core
deadlines will be earlier than normal
This is the hardest thing for a PI to accomplish.
15. Overview of main theme and each project
How the P01 creates synergy--- convince reviewers
that this is best mechanism to fund rather than
RO1’s
Overview charts/place investigators in context—
show the location/equipment, other positive
features available—put the P01 in context.
Put the cores in context—make it clear HOW each
project will use each core.
16. Link investigators
Link topics
Link cores
Show HOW it all fits together visually
17.
18. Humans view an object with a sweep starting at the bottom
central edge around to the right and end up slightly right of
center upper quadrant
Note where the most colorful image is in this figure—its
purple/blue circular—looks kinetic.
This is where you want to put your most colorful
graphic/best data—so the eye sweeps the page and there it
is—slightly right of center in the upper quadrant of the
page.
19. About Your Speaker
Dr. Dorothy Lewis, Professor, Internal
Medicine, Infectious Diseases at the
University of Texas Health Science Center
has a 25-year history of writing grant
applications, including P01 applications.
Her successful track record for winning
grants has given her a valuable “in the
trenches” perspective that can benefit
you, at whichever stage you find yourself.
What You Get:
1. Invite your colleagues to listen in
with you – unlimited listeners
allowed in the same viewing room
2. A FREE recording of the webinar in
CD-ROM, MP4 or PDF Transcript
3. Expert answers to your tough
questions
4. LIVE Question & Answer Session
To Order Online Click Here
Or Call 1-800-303-0129 ext. 506
To Order Online Click Here
Or Call 1-800-303-0129 ext. 506
To Learn More Click Here
20. Besides the PI, is there a trusty assistant---
i.e. a back up plan to change if necessary?
All of this kind of detail needs to be spelled
out
21.
22. How will the group communicate?
How will you distribute information?
How will you resolve conflicts?
How will you decide who is on what paper?
All these details are above and beyond a regular R01
NEED PLANS FOR EACH
23. Communication is key in P01s
How frequently will you meet/talk to each other
via SKYPE, etc.—needs to be spelled out.
Resolution of conflicts is key and a plan must be in
place—usually the institution is the ultimate
arbitrator
24. A reviewer can tell if the grant has been organized.
A reviewer can tell if the PI has read each proposal
and has placed the work in the context of the P01.
Kluging together projects and cores will come
across like you glued it together and thus you will
be unlikely to get in the door.
Especially important to overcome sloppiness—the
reviewer looks upon this as a reflection of both the
PI and the P01.
25.
26. Arctic animals?
Stuck in an ice cube?
Global warming?
Are the people organized?
This is chaos and its obvious it is—without
good organization, this is what your P01 will
end up like.
27. What are the big issues in your field?
Do you have a critical mass in your institution/or
combined with a few other places?
Could brainstorm this at meetings, at study
sections or at your institution.
The best places seem to generate an environment
that fosters these type of interactions
28. Go to institute pages, look for their new initiatives.
At an even earlier stage, look for each institutes
“council approved concepts”
These are areas to start planning for in advance.
Contact suitable program officer to suggest ideas
29. The theme could involve projects all related to
the big concept—cell mediated immunity to
TB
The theme could involve different types of
investigators with different technical expertise
brought together to solve a problem—i.e.
molecular biologists and structural
biologists—to attack a problem at several
levels.
30. Organized around a theme with multiple projects and
a main administrator
Each of the projects should have an independent
investigator—i.e. the project could be stand alone but
because of synergy fits into the P01 mechanism
Depending on institute may be upper limit of costs
that can be requested—for NIGMS--6.5 million direct
for 5 years—meaning a little over 1 million each year—
thus, projects may or may not be full RO1’s (250K)
31. P01s require significant effort on the part of each
participating PI
Effort must be DISTINCT from other efforts—i.e.
watch for overlap with other grants.
Competitive and hard to get—must have a
niche, an organized PI and a great team.
Science must meet the same standards as R01s
32. About Your Speaker
Dr. Dorothy Lewis, Professor, Internal
Medicine, Infectious Diseases at the
University of Texas Health Science Center
has a 25-year history of writing grant
applications, including P01 applications.
Her successful track record for winning
grants has given her a valuable “in the
trenches” perspective that can benefit
you, at whichever stage you find yourself.
What You Get:
1. Invite your colleagues to listen in
with you – unlimited listeners
allowed in the same viewing room
2. A FREE recording of the webinar in
CD-ROM, MP4 or PDF Transcript
3. Expert answers to your tough
questions
4. LIVE Question & Answer Session
To Order Online Click Here
Or Call 1-800-303-0129 ext. 506
To Order Online Click Here
Or Call 1-800-303-0129 ext. 506
To Learn More Click Here
33. Not intended to fund a senior investigator
with satellites—i.e. each project headed by a
bona fide investigator.
Not intended to support a department
Not designed solely to buy a piece of
equipment
34.
35. In my experience, not everyone is good at this.
Must be organized and have help to organize
Must approach the grant in logical steps
Must be able to both encourage and criticize.
Must set goals and deadlines and be able to
enforce without angering people of the group
36. Each Institute may have specific instructions re: how
the P01 is put together.
CONTACT program—provide letter of intent 2
months before due—deadlines are regular ones.
CONTRACT program 6 weeks before deadline because
grants are usually more than 500K.
In general, the projects are all 12 pages
All the budgets and CVs are put together rather than in
individual projects.
This is NOT a mechanism that distributes
developmental grants
37. There MUST be a plan as to how you will all
interact—i.e. meetings, sharing data, etc.
A section called “synergy and interactions among
projects and project leaders”
The preliminary data sections should reflect past
interactions/collaborations amongst members of
the P01
Core leaders should have appropriate expertise to
guide the component
38. Introducing Science Pro Insider
Inside Past Issues:
• Communicating Data-Rich Results – Key Success Factors
• How to Leverage Connections for Private Funding
• R01 or R21? Choose The Appropriate Grant Type
• Dealing with the ‘Negative’ Staffer in your Lab
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39. The organizational structure and administrative
structure is NOT included in the 12 page limit
Should have:
chain of responsibility, external and internal advisory
boards, specific managerial responsibilities, relation of
the organization to the administration of the applicant
institution, consortium arrangements, designation of
replacement for PI
40. Put in an organizational chart of the main theme and
components
Pull together advisory boards that are realistic—need
letters from each members as well as biosketches
How is the grant to be managed—with admin
assistants/trusty assistant? Need to spell this out
41. Need letter from big cheese at institution
praising the P01 and how it meets a need
Must put in organizational chart how the
P01 fits into the institution
Any consortiums should have letters from
their administrative officials
42. Allow at least 6 months—even a year for P01
preparation.
You rush at the expense of organization
DON’T RUSH!!
43.
44. By a big group of investigators with the
breadth of knowledge
Each project is reviewed separately
Each core is reviewed separately
The whole P01 is reviewed as a unit and the
individual project make up the parts, but
maybe not be the sum of the parts.
45.
46. About Your Speaker
Dr. Dorothy Lewis, Professor, Internal
Medicine, Infectious Diseases at the
University of Texas Health Science Center
has a 25-year history of writing grant
applications, including P01 applications.
Her successful track record for winning
grants has given her a valuable “in the
trenches” perspective that can benefit
you, at whichever stage you find yourself.
What You Get:
1. Invite your colleagues to listen in
with you – unlimited listeners
allowed in the same viewing room
2. A FREE recording of the webinar in
CD-ROM, MP4 or PDF Transcript
3. Expert answers to your tough
questions
4. LIVE Question & Answer Session
To Order Online Click Here
Or Call 1-800-303-0129 ext. 506
To Order Online Click Here
Or Call 1-800-303-0129 ext. 506
To Learn More Click Here
47. In 2012, 286 P01’s were submitted, 38 were funded
for a success rate of 13.6% and expenditures of 71
million.
In 2012, 153 P01 renewals were submitted, with 47
funded for a success rate of 31% at 87 million
dollars
Examples of
institutes, NIAID, 13/75, NCI, 21/96, NHBLI, 17/99.
In general, slightly better funding rates than
individual R01’s
48. Successful P01 takes planning/organization and a
good theme
Successful P01 is more than the sum of its parts
Successful P01 take time/effort to pull off
PI is especially critical—their vision and their
organizational skills are put to the test in a P01
49. Introducing Science Pro Insider
Inside Past Issues:
• Communicating Data-Rich Results – Key Success Factors
• How to Leverage Connections for Private Funding
• R01 or R21? Choose The Appropriate Grant Type
• Dealing with the ‘Negative’ Staffer in your Lab
The only Free Monthly eNewsletter
focused on providing best practices on
obtaining grant funding, lab
management, career advice and much more!
SUBSCRIBE TODAY!
Visit http://bit.ly/SciencePro