The heart is the most powerful organ in the circulatory system. It is located in the thoracic cavity between the lungs and pumps blood throughout the body. The heart has four chambers - two atria which receive blood and two ventricles which pump blood out. The right side contains deoxygenated blood while the left side contains oxygenated blood. The heart contracts to pump blood into the arteries and relaxes to receive blood from the veins, ensuring circulation throughout the body.