- Galileo Galilei was the first to use the telescope astronomically in 1609, observing sunspots on the Sun and features on the Moon like seas. His observations of Jupiter's moons provided evidence that bodies can orbit something other than Earth. His observations of Venus' phases provided evidence that Venus orbits the Sun.
- Kepler developed his three laws of planetary motion based on Brahe's astronomical measurements. His laws improved the Copernican model by showing planets orbit in ellipses rather than perfect circles.