Table of Contents for PNAS August 19, 2014 vol. 111 no. 33.
# JOURNAL NAME: Proceedings Of The National Academy Of Sciences Of The United States Of America
# ABBREVIATION: P NATL ACAD SCI USA
# 2013 JCR IMPACT FACTOR: 9.809
Molecular Mechanisms of Radiation Damage. Dmitri Popov
Current medical management of the Acute Radiation Syndromes (ARS) does not include immune prophylaxis based on the Antiradiation Vaccine. Existing principles for the treatment of acute radiation syndromes are based on the replacement and supportive therapy. Haemotopoietic cell transplantation is recomended as an important method of treatment of a Haemopoietic form of the ARS. Though in the different hospitals and institutions, 31 pa-tients with a haemopoietic form have previously undergone transplantation with stem cells, in all cases(100%) the transplantants were rejected. Lethality rate was 87%.(N.Daniak et al. 2005).
Conclusion: Specific antibodies – possible antagonists of Toll like receptors and can inhibit massive activation of lysosomal hydrolytic enzymes and prevent radiation toxicity after high doses of Radiation.
Molecular Mechanisms of Radiation Damage. Dmitri Popov
Current medical management of the Acute Radiation Syndromes (ARS) does not include immune prophylaxis based on the Antiradiation Vaccine. Existing principles for the treatment of acute radiation syndromes are based on the replacement and supportive therapy. Haemotopoietic cell transplantation is recomended as an important method of treatment of a Haemopoietic form of the ARS. Though in the different hospitals and institutions, 31 pa-tients with a haemopoietic form have previously undergone transplantation with stem cells, in all cases(100%) the transplantants were rejected. Lethality rate was 87%.(N.Daniak et al. 2005).
Conclusion: Specific antibodies – possible antagonists of Toll like receptors and can inhibit massive activation of lysosomal hydrolytic enzymes and prevent radiation toxicity after high doses of Radiation.
The Effect of Gamma Irradiation on the Radiofrequency Dielectric Dispersion P...theijes
The International Journal of Engineering & Science is aimed at providing a platform for researchers, engineers, scientists, or educators to publish their original research results, to exchange new ideas, to disseminate information in innovative designs, engineering experiences and technological skills. It is also the Journal's objective to promote engineering and technology education. All papers submitted to the Journal will be blind peer-reviewed. Only original articles will be published.
The Effect of Gamma Irradiation on the Radiofrequency Dielectric Dispersion P...theijes
The International Journal of Engineering & Science is aimed at providing a platform for researchers, engineers, scientists, or educators to publish their original research results, to exchange new ideas, to disseminate information in innovative designs, engineering experiences and technological skills. It is also the Journal's objective to promote engineering and technology education. All papers submitted to the Journal will be blind peer-reviewed. Only original articles will be published.
Wagner College Forum for Undergraduate Research, Vol. 16 No. 1Wagner College
The Fall 2017 issue contains abstracts by Monica Cipriani, Merrysha Castillo, Regina Ismaili, Helema Tayeh & Anna Cios, Alexis Dispensa, Lejla Bolevic & Domenick Palmieri, Theresa Mustacchio, Anthony Tucker-Bartley, Michelle DeTomaso and Nicole Bell. It also contains articles by Shannon Cedeno, Nicole Aylmer, Nada Metwally, Robin Santoro, Vanessa Dailey, Madison McNichol, Cynedra Osinaike, Madison J. Ruff, Daniel S. Smith, Rebecca Martin and Kelly Glenn.
Doping the quantum dots is one of the most emerging hot topics. In addition to the enhancement of the optical properties of the quantum dots, it also improve the chemical stability and inhibit the self quenching effect in the undoped quantum dots. In addition to that, It opened the field of using non Cadmium based quantum dots, that will be very useful for various biological applications.
해당 잡지사의 허락을 받고 공유합니다. 다운로드 가능합니다.
[이달의 신기술]에 '기후변화 시뮬레이션이 던지는 시사점'이라는 제목으로 원고를 부탁받아서 작성한 글입니다.
[이달의 신기술]은 <이달의 신기술>은 산업통상자원부가 후원하여 R&D 전담기관인 한국산업기술평가관리원, 한국에너지기술평가원, 한국산업기술진흥원 및 한국공학한림원 공동으로 발행되는 매거진입니다.
원고에서 저는 기후변화가 주는 위험 요인과 기회 요인을 언급했습니다. 관심있는 분은 읽고 공유해 주시면 고맙겠습니다.
정창권 드림
Benjamin@System-Leadership.org
비록 박정희와 육사 동기지만 5.16에 가담하지 않았고 유신체제에 대한 비판의식이 있었던 김재규. 그는 재판에서도 박정희에 대한 ‘각하' 호칭을 사용하는 등의 한계가 있었지만 민주주의에 대한 확고한 역사관 철학으로 네 번째 저격으로 뜻을 이뤘다. 혼란스러운 과도기에 전두환은 치밀하고 신속하게 정권을 찬탈했다. 박정희와 그 옹호 세력들이 일을 처리하는 방식은 큰 충격을 준다.
기획재정부가 보내 준 공식자료(보도 자료)를 공유합니다.
이 자료가 필요하신 분에게 적절히 사용되기를 바랍니다.
(보도자료) 긴급 거시경제금융회의 개최결과
(보도자료) 2015회계연도 세입․세출 마감 결과 - 세계잉여금 4년만에 흑자로 전환 (2.8조원) -
(보도자료) 민생안정과 경제활력제고를 위한조속 처리 필요 법안 주요내용
(보도참고) 「증세는 없다?…작년 월급쟁이 세금 6.7%증가」제하 기사 관련
(보도참고) 「연금저축의 배신」제하 기사 관련
cf) 2015년 공공기관 경영평가 위원으로서 받은 자료입니다. 담당부서의 승인을 받아 원문을 공유합니다.
ʱ (보도) 누리과정의 차질없는 시행 및 교육환경 개선을 위해 ‘16년 목적예비비 3,000억원 지원
ʲ (보도참고) 「2015 대한민국 정책평가」 기사 ‘공공기관 임금피크제’ 관련 (2015.11.30., 12.2 동아일보)
ʳ (보도참고) 위안화의 SDR 바스켓 편입의 영향 및 대응방향-
ʴ (보도) 2015년도 세법개정안 주요내용과 의미
※ 본 자료는 기획재정부가 운영하는 위원회 및 자문단 소속 위원님께 정책의 이해를 돕기 위하여 보내드리는 자료입니다. 주1회 현안이슈에 대한 기획재정부의 입장이 담긴 자료를 보내드립니다.
2015년 공공기관 경영평가 위원으로서 받은 자료입니다. 담당부서의 승인을 받아 원문을 공유합니다.
ʱ (보도참고) 최경환 부총리, 한중 FTA 등 조속한 비준처리 촉구 (제51회 국무회의 FTA비준 관련 발언, 한·중, 한·베, 한·뉴 FTA 영향평가 결과 및 보완대책)
ʲ (보도참고) 국민일보, 「서비스법 통과땐 일자리 69만개 생긴다는데...과연?」 제하 기사 관련
ʳ (보도참고) ‘15년 3/4분기 가계동향 분석 “가계소득 0.7% 증가, 소득분배 개선세 지속”
ʴ (보도) 「제13차 재정관리점검 회의」 - 2016년 예산을 연초부터 즉시 집행할 수 있도록 사전준비 완료
※ 본 자료는 기획재정부가 운영하는 위원회 및 자문단 소속 위원님께 정책의 이해를 돕기 위하여 보내드리는 자료입니다. 주1회 현안이슈에 대한 기획재정부의 입장이 담긴 자료를 보내드립니다.
내 인생의 소중한 가치 10가지를 쓰는 훈련을 위해 저의 소중한 가치를 소개합니다. 나의 소중한 가치는 중요한 의사결정을 할 때의 기준이 됩니다. 따라서 나에게 헌법과 같은 의미입니다.
하지만 완성된 것으로 보면 안됩니다. 내용도 바뀔 수 있습니다. 또한 이 가치를 현재 내가 잘 지키고 있다는 뜻이 아닙니다. 나의 지향점을 의미합니다. 그 이상도 그 이하도 아닙니다. 현재 이런 모습이 아닐지라도 그런 모습으로 이끌어 갈 수 있는 힘을 받을 수 있습니다.
편하게 작성해 보십시오. 그리고 계속 수정하십시오. 저는 이 내용을 3년 동안 수정하면서 완성한 것입니다.
정창권 드림
경영학 박사, cck@K-Bridge.org
2015년 9월 24일 기획재정부
ㅇ 기업·공공기관에서 사회적 가치를 실현하는 기관을 대상으로 지원하는 사회공헌사업 중 지속적으로 진행되고 있는 프로그램을 발췌하여 안내하오니 (사회적)협동조합에서는 지원자격, 지원내용 등을 확인하시어 향후 사회공헌프로그램 공모에 대비하시기 바랍니다.
ㅇ 특히 한국전력공사의 사회공헌 프로그램은 '15.9월 이후 진행되오니 금융지원 등이 필요한 협동조합은 적극 참가하시기 바랍니다.
※ 신청 요건 및 절차, 문의처 등 자세한 내용은 첨부의 자료를 참고하시기 바랍니다.
출처: 한국사회적기업진흥원 http://bit.ly/1NTYTeB
www.facebook.com/EcoSocialEconomy
HBR 2014년 5월호 Cover Story가 Resilient Company 였습니다. 자연재해와 천연자원의 고갈이 기업이 관리해야 하는 원가 위협/수익 위협 요인이어서 속수무책으로 당하지 말자는 취지에서 resilience를 키워야 하는 관점을 보이고 있습니다.
기존의 efficiency와 원가 절감을 단기적인 관점으로 돌려버리고 장기적인 관점에서 기업의 경영에 도움이 되기 위해서라도 efficiency에 반대되는 diversity를 키워야 하고 원가 절감에 반대되는 것처럼 보이는 redundancy를 중요시 해야한다는 주장을 하고 있습니다. 이것이 HBR이 관심을 가지고 있는 새로운 자본주의/ 기업 경영 원리로 자리잡고 있습니다.
동영상 강의와 연결해서 보시면 도움이 되실겁니다
동영상 라이브 강의 : http://goo.gl/8QCAQV
동영상 강의 목차 :
1. 강의 점검 및 강의소개 : 5분 55초 - 6분 29초
2. hbr 활용법 : 6분 30초 - 14분 11초
3. resilience의 개념 : 14분 12초 - 23분 14초
4. 본론 :23분 15초 - 1시간 19분 29초
5. 토론 : 1시간 19분 30초- 1시간 49분 59초
6. 정리 : 1시간 50분 - 끝까지
본 과정은 석, 박사 과정입니다.
에코 컨텐츠를 세상과 소통시키는 것에 관심있는 여성 인재들을 환영합니다.
본 사업단을 위해 교과목으로 [에코 크리에이티브 협동과정]이라는 석, 박사 과정을 새로 개설하였으며, 이 협동과정에는 자연대, 미대(산업디자인), 언론홍보영상학과, 사범대가 함께 합니다.
21세기는 에코가 경쟁력입니다. 본 협동과정과 사업단의 다양한 활동을 통해 다양성(Diversity)가 왜 기업, 사회, 인류의 생존 대안이 될수밖에 없는지 확인하시고 새로운 길을 열어보기 바랍니다.
관련 문의 : 민주영 (이화여자대학교 에코과학 창조아카데미 사업단)
T. 3277-3868 e600118@ewha.ac.kr
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Table of Contents for PNAS August 19, 2014 vol. 111 no. 33.
1. Cover image: Pictured is Mount Etna during a summit eruption on January 5, 2012. Robina
Shaheen et al. measured sulfur aerosol isotope levels contained in snow pit samples collected
at the South Pole to track anomalous peaks between 1984 and 2001 and identify their origins.
In addition to sulfur aerosol isotope peaks that correlated with volcanic eruptions, the highest
peak occurred during a 1997–1998 El Niño Southern Oscillation event. Sulfur aerosol isotope
levels are related to biomass and fossil fuel burning, carbonyl sulfide emissions, and atmo-spheric
dynamics, and they resemble sulfur anomalies observed in the Precambrian. See
the article by Shaheen et al. on pages 11979–11983. Image courtesy of Nicole Bobrowski
(University of Heidelberg, Heidelberg).
From the Cover
11979 Implications of atmospheric sulfur isotopes
11943 Printable diodes
12103 Bacteria and organic pollutants
12199 Environmental influence on pathogenicity
12222 Transmission of learned fears
Contents
THIS WEEK IN PNAS
11907 In This Issue
LETTERS (ONLINE ONLY)
E3362 Cleaning up the record on the maximal information
coefficient and equitability
David N. Reshef, Yakir A. Reshef, Michael Mitzenmacher,
and Pardis C. Sabeti
E3364 Reply to Reshef et al.: Falsifiability or bust
Justin B. Kinney and Gurinder S. Atwal
E3365 Getting “function” right
Tyler D. P. Brunet and W. Ford Doolittle
E3366 Reply to Brunet and Doolittle: Both selected effect
and causal role elements can influence human
biology and disease
Manolis Kellis, Barbara Wold, Michael P. Snyder, Bradley E.
Bernstein, Anshul Kundaje, Georgi K. Marinov, Lucas D.
Ward, Ewan Birney, Gregory E. Crawford, Job Dekker,
Ian Dunham, Laura L. Elnitski, Peggy J. Farnham, Elise A.
Feingold, Mark Gerstein, Morgan C. Giddings, David M.
Gilbert, Thomas R. Gingeras, Eric D. Green, Roderic Guigo,
Tim Hubbard, Jim Kent, Jason D. Lieb, Richard M. Myers,
Michael J. Pazin, Bing Ren, John Stamatoyannopoulos,
Zhiping Weng, Kevin P. White, and Ross C. Hardison
NEWS FEATURE—An in-depth look at trending science issues
11909 News Feature: How to light a cosmic candle
Nadia Drake
PROFILE
11912 Profile of Alexander D. Johnson
Tinsley H. Davis
See Inaugural Article on page 10404 in issue 29 of volume 111
COMMENTARIES
11915 Dopamine challenge reveals neuroadaptive changes
in marijuana abusers
Bertha K. Madras
See companion article on page E3149 in issue 30 of
volume 111
11917 Printed diodes operating at mobile phone frequencies
Antonio Facchetti
See companion article on page 11943
11919 PCB dechlorinases revealed at last
Donna L. Bedard
See companion article on page 12103
PNAS PLUS
11921 Significance Statements
Brief statements written by the authors about the significance of
their papers.
August 19, 2014 u vol. 111 u no. 33 u 11907–12270
Free online through the PNAS open access option.
PNAS u August 19, 2014 u vol. 111 u no. 33 u iii–vii
2. INAUGURAL ARTICLE
11924 Threonine-4 of the budding yeast RNAP II CTD couples
transcription with Htz1-mediated chromatin remodeling
Emanuel Rosonina, Nathan Yurko, Wencheng Li,
Mainul Hoque, Bin Tian, and James L. Manley
PHYSICAL SCIENCES
APPLIED PHYSICAL SCIENCES
11932 Duration of urination does not change with body size
Patricia J. Yang, Jonathan Pham, Jerome Choo,
and David L. Hu
11938 Two-axis control of a singlet–triplet qubit with an
integrated micromagnet
Xian Wu, D. R. Ward, J. R. Prance, Dohun Kim, John King
Gamble, R. T. Mohr, Zhan Shi, D. E. Savage, M. G. Lagally,
Mark Friesen, S. N. Coppersmith, and M. A. Eriksson
11943 All-printed diode operating at 1.6 GHz
Negar Sani, Mats Robertsson, Philip Cooper, Xin Wang,
Magnus Svensson, Peter Andersson Ersman, Petronella
Norberg, Marie Nilsson, David Nilsson, Xianjie Liu, Hjalmar
Hesselbom, Laurent Akesso, Mats Fahlman, Xavier Crispin,
Isak Engquist, Magnus Berggren, and Göran Gustafsson
See Commentary on page 11917
11949 Acoustic excitations and elastic heterogeneities in
disordered solids
Hideyuki Mizuno, Stefano Mossa, and Jean-Louis Barrat
CHEMISTRY
11955 Scalable NMR spectroscopy with semiconductor chips
Dongwan Ha, Jeffrey Paulsen, Nan Sun, Yi-Qiao Song,
and Donhee Ham
EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES
11961 Rare events in earth history include the LB1 human
skeleton from Flores, Indonesia, as a developmental
singularity, not a unique taxon
Robert B. Eckhardt, Maciej Henneberg, Alex S. Weller,
and Kenneth J. Hsü
11967 Evolved developmental homeostasis disturbed in LB1
from Flores, Indonesia, denotes Down syndrome and not
diagnostic traits of the invalid species Homo floresiensis
Maciej Henneberg, Robert B. Eckhardt, Sakdapong
Chavanaves, and Kenneth J. Hsü
11973 Testing for ontological errors in probabilistic forecasting
models of natural systems
Warner Marzocchi and Thomas H. Jordan
11979 Large sulfur-isotope anomaly in nonvolcanic sulfate
aerosol and its implications for the Archean atmosphere
Robina Shaheen, Mariana M. Abaunza, Teresa L. Jackson,
Justin McCabe, Joël Savarino, and Mark H. Thiemens
ENGINEERING
11984 Universal mobile electrochemical detector designed
for use in resource-limited applications
Alex Nemiroski, Dionysios C. Christodouleas, Jonathan W.
Hennek, Ashok A. Kumar, E. Jane Maxwell, Maria Teresa
Fernández-Abedul, and George M. Whitesides
11990 A robust nanoscale experimental quantification of
fracture energy in a bilayer material system
Denvid Lau, Kurt Broderick, Markus J. Buehler,
and Oral Büyüköztürk
PHYSICS
E3367 Robust excitons inhabit soft supramolecular nanotubes
Dörthe M. Eisele, Dylan H. Arias, Xiaofeng Fu, Erik A.
Bloemsma, Colby P. Steiner, Russell A. Jensen, Patrick
Rebentrost, Holger Eisele, Andrei Tokmakoff, Seth Lloyd,
Keith A. Nelson, Daniela Nicastro, Jasper Knoester,
and Moungi G. Bawendi
E3386 Free-energy inference from partial work measurements
in small systems
Marco Ribezzi-Crivellari and Felix Ritort
12109 Artificial selection for structural color on butterfly wings
and comparison with natural evolution
Bethany R. Wasik, Seng Fatt Liew, David A. Lilien, April J.
Dinwiddie, Heeso Noh, Hui Cao, and Antónia Monteiro
SUSTAINABILITY SCIENCE
11996 Land, irrigation water, greenhouse gas, and reactive
nitrogen burdens of meat, eggs, and dairy production
in the United States
Gidon Eshel, Alon Shepon, Tamar Makov, and Ron Milo
SOCIAL SCIENCES
PSYCHOLOGICAL AND COGNITIVE SCIENCES
12002 Nonliteral understanding of number words
Justine T. Kao, Jean Y. Wu, Leon Bergen,
and Noah D. Goodman
12252 A computational and neural model of momentary
subjective well-being
Robb B. Rutledge, Nikolina Skandali, Peter Dayan,
and Raymond J. Dolan
BIOLOGICAL SCIENCES
APPLIED BIOLOGICAL SCIENCES
11932 Duration of urination does not change with body size
Patricia J. Yang, Jonathan Pham, Jerome Choo,
and David L. Hu
12008 Antibody-based delivery of IL4 to the neovasculature
cures mice with arthritis
Teresa Hemmerle, Fabia Doll, and Dario Neri
12013 Lignin valorization through integrated biological
funneling and chemical catalysis
Jeffrey G. Linger, Derek R. Vardon, Michael T. Guarnieri,
Eric M. Karp, Glendon B. Hunsinger, Mary Ann Franden,
Christopher W. Johnson, Gina Chupka, Timothy J.
Strathmann, Philip T. Pienkos, and Gregg T. Beckham
BIOCHEMISTRY
E3376 Spliceostatin hemiketal biosynthesis in Burkholderia
spp. is catalyzed by an iron/α-ketoglutarate–
dependent dioxygenase
Alessandra S. Eustáquio, Jeffrey E. Janso, Anokha S.
Ratnayake, Christopher J. O’Donnell, and Frank E. Koehn
iv u www.pnas.org
3. 11924 Threonine-4 of the budding yeast RNAP II CTD couples
transcription with Htz1-mediated chromatin remodeling
Emanuel Rosonina, Nathan Yurko, Wencheng Li,
Mainul Hoque, Bin Tian, and James L. Manley
12019 Disassembly of mitotic checkpoint complexes by the
joint action of the AAA-ATPase TRIP13 and p31comet
Esther Eytan, Kexi Wang, Shirly Miniowitz-Shemtov,
Danielle Sitry-Shevah, Sharon Kaisari, Tim J. Yen,
Song-Tao Liu, and Avram Hershko
12025 Broad and adaptable RNA structure recognition by
the human interferon-induced tetratricopeptide
repeat protein IFIT5
George E. Katibah, Yidan Qin, David J. Sidote, Jun Yao,
Alan M. Lambowitz, and Kathleen Collins
12031 Structural investigation of ribosomally synthesized
natural products by hypothetical structure enumeration
and evaluation using tandem MS
Qi Zhang, Manuel Ortega, Yanxiang Shi, Huan Wang,
Joel O. Melby, Weixin Tang, Douglas A. Mitchell,
and Wilfred A. van der Donk
12037 Variable cooperativity in SNARE-mediated membrane
fusion
Javier M. Hernandez, Alex J. B. Kreutzberger, Volker
Kiessling, Lukas K. Tamm, and Reinhard Jahn
12043 Circadian rhythm of hyperoxidized peroxiredoxin II
is determined by hemoglobin autoxidation and the
20S proteasome in red blood cells
Chun-Seok Cho, Hyun Ju Yoon, Jeong Yeon Kim,
Hyun Ae Woo, and Sue Goo Rhee
BIOPHYSICS AND COMPUTATIONAL BIOLOGY
E3386 Free-energy inference from partial work measurements
in small systems
Marco Ribezzi-Crivellari and Felix Ritort
E3395 Protective hinge in insulin opens to enable its receptor
engagement
John G. Menting, Yanwu Yang, Shu Jin Chan, Nelson B.
Phillips, Brian J. Smith, Jonathan Whittaker, Nalinda P.
Wickramasinghe, Linda J. Whittaker, Vijay Pandyarajan,
Zhu-li Wan, Satya P. Yadav, Julie M. Carroll, Natalie
Strokes, Charles T. Roberts, Jr., Faramarz Ismail-Beigi,
Wieslawa Milewski, Donald F. Steiner, Virander S.
Chauhan, Colin W. Ward, Michael A. Weiss,
and Michael C. Lawrence
12049 Order and disorder control the functional
rearrangement of influenza hemagglutinin
Xingcheng Lin, Nathanial R. Eddy, Jeffrey K. Noel,
Paul C. Whitford, Qinghua Wang, Jianpeng Ma,
and José N. Onuchic
12055 Allostery within a transcription coactivator is
predominantly mediated through dissociation
rate constants
Sarah L. Shammas, Alexandra J. Travis, and Jane Clarke
12061 Dissecting allosteric effects of activator–coactivator
complexes using a covalent small molecule ligand
Ningkun Wang, Jean M. Lodge, Carol A. Fierke,
and Anna K. Mapp
12067 Prepaying the entropic cost for allosteric regulation
in KIX
Sean M. Law, Jessica K. Gagnon, Anna K. Mapp,
and Charles L. Brooks III
12073 The ribosome uses cooperative conformational changes
to maximize and regulate the efficiency of translation
Wei Ning, Jingyi Fei, and Ruben L. Gonzalez, Jr.
12079 Energetically significant networks of coupled
interactions within an unfolded protein
Jae-Hyun Cho, Wenli Meng, Satoshi Sato, Eun Young Kim,
Hermann Schindelin, and Daniel P. Raleigh
CELL BIOLOGY
E3405 Cyclin D3 promotes pancreatic β-cell fitness and viability
in a cell cycle-independent manner and is targeted in
autoimmune diabetes
Noemí Alejandra Saavedra-Ávila, Upasana Sengupta,
Begoña Sánchez, Ester Sala, Laura Haba, Thomas
Stratmann, Joan Verdaguer, Dídac Mauricio, Belén
Mezquita, Ana Belén Ropero, Ángel Nadal,
and Conchi Mora
12085 Prion-like proteins sequester and suppress the toxicity
of huntingtin exon 1
Can Kayatekin, Kent E. S. Matlack, William R. Hesse,
Yinghua Guan, Sohini Chakrabortee, Jenny Russ,
Erich E. Wanker, Jagesh V. Shah, and Susan Lindquist
12091 UBR5-mediated ubiquitination of ATMIN is required
for ionizing radiation-induced ATM signaling
and function
Tianyi Zhang, Janet Cronshaw, Nnennaya Kanu,
Ambrosius P. Snijders, and Axel Behrens
DEVELOPMENTAL BIOLOGY
12097 Hypertrophic chondrocytes can become osteoblasts
and osteocytes in endochondral bone formation
Liu Yang, Kwok Yeung Tsang, Hoi Ching Tang,
Danny Chan, and Kathryn S. E. Cheah
ENVIRONMENTAL SCIENCES
12103 Genomic characterization of three unique
Dehalococcoides that respire on persistent
polychlorinated biphenyls
Shanquan Wang, Kern Rei Chng, Andreas Wilm,
Siyan Zhao, Kun-Lin Yang, Niranjan Nagarajan,
and Jianzhong He
See Commentary on page 11919
EVOLUTION
11961 Rare events in earth history include the LB1 human
skeleton from Flores, Indonesia, as a developmental
singularity, not a unique taxon
Robert B. Eckhardt, Maciej Henneberg, Alex S. Weller,
and Kenneth J. Hsü
11967 Evolved developmental homeostasis disturbed in LB1
from Flores, Indonesia, denotes Down syndrome and not
diagnostic traits of the invalid species Homo floresiensis
Maciej Henneberg, Robert B. Eckhardt, Sakdapong
Chavanaves, and Kenneth J. Hsü
12109 Artificial selection for structural color on butterfly wings
and comparison with natural evolution
Bethany R. Wasik, Seng Fatt Liew, David A. Lilien, April J.
Dinwiddie, Heeso Noh, Hui Cao, and Antónia Monteiro
12115 Temperate origins of long-distance seasonal migration
in New World songbirds
Benjamin M. Winger, F. Keith Barker, and Richard H. Ree
PNAS u August 19, 2014 u vol. 111 u no. 33 u v
4. 12121 Different tradeoffs result from alternate genetic
adaptations to a common environment
Alejandra Rodríguez-Verdugo, David Carrillo-Cisneros,
Andrea González-González, Brandon S. Gaut,
and Albert F. Bennett
12127 Pervasive domestication of defective prophages
by bacteria
Louis-Marie Bobay, Marie Touchon,
and Eduardo P. C. Rocha
GENETICS
E3415 Short sequences can efficiently recruit histone H3 lysine
27 trimethylation in the absence of enhancer activity
and DNA methylation
Philip Jermann, Leslie Hoerner, Lukas Burger,
and Dirk Schübeler
12133 The PML domain of PML–RARα blocks senescence to
promote leukemia
Katharina Korf, Harald Wodrich, Alexander Haschke,
Corinne Ocampo, Lena Harder, Friederike Gieseke,
Annika Pollmann, Kevin Dierck, Sebastian Prall, Hannah
Staege, Hui Ma, Martin A. Horstmann, Ronald M. Evans,
and Thomas Sternsdorf
IMMUNOLOGY AND INFLAMMATION
E3422 IL-17 drives psoriatic inflammation via distinct, target
cell-specific mechanisms
Hye-Lin Ha, Hongshan Wang, Prapaporn Pisitkun,
Jin-Chul Kim, Ilaria Tassi, Wanhu Tang, Maria I.
Morasso, Mark C. Udey, and Ulrich Siebenlist
E3432 Critical role of all-trans retinoic acid in stabilizing
human natural regulatory T cells under inflammatory
conditions
Ling Lu, Qin Lan, Zhiyuan Li, Xiaohui Zhou, Jian Gu,
Qiang Li, Julie Wang, Maogen Chen, Ya Liu, Yi Shen,
David D. Brand, Bernhard Ryffel, David A. Horwitz,
Francisco P. Quismorio, Zhongmin Liu, Bin Li,
Nancy J. Olsen, and Song Guo Zheng
12139 Fibroblastic reticular cells of the lymph node are required
for retention of resting but not activated CD8+ T cells
Alice E. Denton, Edward W. Roberts, Michelle A. Linterman,
and Douglas T. Fearon
12145 Impaired selectin-dependent leukocyte recruitment
induces T-cell exhaustion and prevents chronic
allograft vasculopathy and rejection
Bara Sarraj, Junsheng Ye, Ahmed Ibrahim Akl, Guodong
Chen, Jiao-Jing Wang, Zheng Zhang, Farida Abadja,
Michael Abecassis, Stephen D. Miller, Geoffrey S. Kansas,
and M. Javeed Ansari
12151 Functional B-1 progenitor cells are present in the
hematopoietic stem cell-deficient embryo and depend
on Cbfβ for their development
Michihiro Kobayashi, W. Christopher Shelley, Wooseok Seo,
Sasidhar Vemula, Yang Lin, Yan Liu, Reuben Kapur,
Ichiro Taniuchi, and Momoko Yoshimoto
12157 Linkage of inflammation and oxidative stress via release
of glutathionylated peroxiredoxin-2, which acts as
a danger signal
Sonia Salzano, Paola Checconi, Eva-Maria Hanschmann,
Christopher Horst Lillig, Lucas D. Bowler, Philippe Chan,
David Vaudry, Manuela Mengozzi, Lucia Coppo, Sandra
Sacre, Kondala R. Atkuri, Bita Sahaf, Leonard A. Herzenberg,
Leonore A. Herzenberg, Lisa Mullen, and Pietro Ghezzi
12163 Oxysterols are agonist ligands of RORγt and drive
Th17 cell differentiation
Pejman Soroosh, Jiejun Wu, Xiaohua Xue, Jiao Song,
Steven W. Sutton, Marciano Sablad, Jingxue Yu, Marina I.
Nelen, Xuejun Liu, Glenda Castro, Rosa Luna, Shelby
Crawford, Homayon Banie, Rose A. Dandridge, Xiaohu
Deng, Anton Bittner, Chester Kuei, Mandana Tootoonchi,
Natasha Rozenkrants, Krystal Herman, Jingjin Gao, Xia V.
Yang, Kacey Sachen, Karen Ngo, Wai-Ping Fung-Leung,
Steven Nguyen, Aimee de Leon-Tabaldo, Jonathan Blevitt,
Yan Zhang, Maxwell D. Cummings, Tadimeti Rao,
Neelakandha S. Mani, Changlu Liu, Murray McKinnon,
Marcos E. Milla, Anne M. Fourie, and Siquan Sun
MEDICAL SCIENCES
12169 Circulating microRNA profiles in human patients with
acetaminophen hepatotoxicity or ischemic hepatitis
Jeanine Ward, Chitra Kanchagar, Isana Veksler-Lublinsky,
Rosalind C. Lee, Mitchell R. McGill, Hartmut Jaeschke,
Steven C. Curry, and Victor R. Ambros
12175 Multimonth controlled small molecule release from
biodegradable thin films
Bryan B. Hsu, Myoung-Hwan Park, Samantha R.
Hagerman, and Paula T. Hammond
12181 Sequential combination therapy of ovarian cancer
with degradable N-(2-hydroxypropyl)methacrylamide
copolymer paclitaxel and gemcitabine conjugates
Rui Zhang, Jiyuan Yang, Monika Sima, Yan Zhou,
and Jindrich Kopeˇcek
12187 Distinct patterns of hepcidin and iron regulation during
HIV-1, HBV, and HCV infections
Andrew E. Armitage, Andrea R. Stacey, Eleni Giannoulatou,
Elizabeth Marshall, Pamela Sturges, Kamaljit Chatha,
Nicola M. G. Smith, XiaoJie Huang, XiaoNing Xu,
Sant-Rayn Pasricha, Ning Li, Hao Wu, Craig Webster,
Andrew M. Prentice, Pierre Pellegrino, Ian Williams,
Phillip J. Norris, Hal Drakesmith, and Persephone Borrow
MICROBIOLOGY
E3441 Cross-resistance mechanism of respiratory syncytial
virus against structurally diverse entry inhibitors
Dan Yan, Sujin Lee, Vidhi D. Thakkar, Ming Luo,
Martin L. Moore, and Richard Karl Plemper
E3450 Synthesis and scavenging role of furan fatty acids
Rachelle A. S. Lemke, Amelia C. Peterson, Eva C.
Ziegelhoffer, Michael S. Westphall, Henrik Tjellström,
Joshua J. Coon, and Timothy J. Donohue
12193 Modeling host interactions with hepatitis B virus using
primary and induced pluripotent stem cell-derived
hepatocellular systems
Amir Shlomai, Robert E. Schwartz, Vyas Ramanan,
Ankit Bhatta, Ype P. de Jong, Sangeeta N. Bhatia,
and Charles M. Rice
12199 Transient Darwinian selection in Salmonella enterica
serovar Paratyphi A during 450 years of global spread
of enteric fever
Zhemin Zhou, Angela McCann, François-Xavier Weill,
Camille Blin, Satheesh Nair, John Wain, Gordon Dougan,
and Mark Achtman
12205 Fungal negative-stranded RNA virus that is related to
bornaviruses and nyaviruses
Lijiang Liu, Jiatao Xie, Jiasen Cheng, Yanping Fu,
Guoqing Li, Xianhong Yi, and Daohong Jiang
vi u www.pnas.org
5. 12211 Temporal and spatial organization of ESCRT protein
recruitment during HIV-1 budding
Marina Bleck, Michelle S. Itano, Daniel S. Johnson,
V. Kaye Thomas, Alison J. North, Paul D. Bieniasz,
and Sanford M. Simon
NEUROSCIENCE
E3458 T-cell TGF-β signaling abrogation restricts
medulloblastoma progression
David Gate, Moise Danielpour, Javier Rodriguez, Jr., Gi-Bum
Kim, Rachelle Levy, Serguei Bannykh, Joshua J. Breunig,
Susan M. Kaech, Richard A. Flavell, and Terrence Town
E3467 Curvature-processing network in macaque visual cortex
Xiaomin Yue, Irene S. Pourladian, Roger B. H. Tootell,
and Leslie G. Ungerleider
12217 Competition between recently potentiated synaptic
inputs reveals a winner-take-all phase of synaptic
tagging and capture
Sreedharan Sajikumar, Richard G. M. Morris,
and Martin Korte
12222 Intergenerational transmission of emotional trauma
through amygdala-dependent mother-to-infant
transfer of specific fear
Jacek Debiec and Regina Marie Sullivan
12228 Lactate promotes plasticity gene expression by
potentiating NMDA signaling in neurons
Jiangyan Yang, Evelyne Ruchti, Jean-Marie Petit,
Pascal Jourdain, Gabriele Grenningloh, Igor Allaman,
and Pierre J. Magistretti
PHARMACOLOGY
12234 Dimerization of HIV-1 protease occurs through
two steps relating to the mechanism of protease
dimerization inhibition by darunavir
Hironori Hayashi, Nobutoki Takamune, Takashi Nirasawa,
Manabu Aoki, Yoshihiko Morishita, Debananda Das,
Yasuhiro Koh, Arun K. Ghosh, Shogo Misumi,
and Hiroaki Mitsuya
PHYSIOLOGY
E3476 Robust efficiency and actuator saturation explain
healthy heart rate control and variability
Na Li, Jerry Cruz, Chenghao Simon Chien, Somayeh
Sojoudi, Benjamin Recht, David Stone, Marie Csete,
Daniel Bahmiller, and John C. Doyle
12240 Overexpression of junctophilin-2 does not enhance
baseline function but attenuates heart failure
development after cardiac stress
Ang Guo, Xiaoying Zhang, Venkat Ramesh Iyer, Biyi Chen,
Caimei Zhang, William J. Kutschke, Robert M. Weiss,
Clara Franzini-Armstrong, and Long-Sheng Song
PLANT BIOLOGY
E3486 Structural basis for the recognition–evasion arms
race between Tomato mosaic virus and the
resistance gene Tm-1
Kazuhiro Ishibashi, Yuichiro Kezuka, Chihoko
Kobayashi, Masahiko Kato, Tsuyoshi Inoue, Takamasa
Nonaka, Masayuki Ishikawa, Hiroyoshi Matsumura,
and Etsuko Katoh
12246 Novel carotenoid cleavage dioxygenase catalyzes
the first dedicated step in saffron crocin
biosynthesis
Sarah Frusciante, Gianfranco Diretto, Mark
Bruno, Paola Ferrante, Marco Pietrella, Alfonso
Prado-Cabrero, Angela Rubio-Moraga, Peter
Beyer, Lourdes Gomez-Gomez, Salim Al-Babili,
and Giovanni Giuliano
PSYCHOLOGICAL AND COGNITIVE SCIENCES
12252 A computational and neural model of momentary
subjective well-being
Robb B. Rutledge, Nikolina Skandali, Peter Dayan,
and Raymond J. Dolan
12258 Plasma oxytocin concentrations and OXTR
polymorphisms predict social impairments in
children with and without autism spectrum disorder
Karen J. Parker, Joseph P. Garner, Robin A. Libove,
Shellie A. Hyde, Kirsten B. Hornbeak, Dean S. Carson,
Chun-Ping Liao, Jennifer M. Phillips, Joachim F.
Hallmayer, and Antonio Y. Hardan
SYSTEMS BIOLOGY
12264 Epigenetic coordination of embryonic heart
transcription by dynamically regulated long
noncoding RNAs
Scot J. Matkovich, John R. Edwards, Tiffani C.
Grossenheider, Cristina de Guzman Strong,
and Gerald W. Dorn II
RETRACTION
MEDICAL SCIENCES
12270 XMRV is present in malignant prostatic epithelium
and is associated with prostate cancer, especially
high-grade tumors
Robert Schlaberg, Daniel J. Choe, Kristy R. Brown,
Harshwardhan M. Thaker, and Ila R. Singh
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