Treatment of Extremely Displaced and Impacted Second Premolar in the MandibleAbu-Hussein Muhamad
The mandibular second premolar is one of the most frequently impacted teeth. The recommended treatment is to extract the second primary molar with or without removing the bone along the eruption path, to uncover the tooth surgically and move it into the arch by orthodontic treatment. The purpose of this article is to review the principles of case management of soft tissue impacted second premolars mandibular and to illustrate their potential to respond well to the treatment. Although the scope of treatment may depend on a varying range of factors, this case report demonstrates the inherent potential for good treatment outcome in cases of soft tissue impactions.
Treatment of Extremely Displaced and Impacted Second Premolar in the MandibleAbu-Hussein Muhamad
The mandibular second premolar is one of the most frequently impacted teeth. The recommended treatment is to extract the second primary molar with or without removing the bone along the eruption path, to uncover the tooth surgically and move it into the arch by orthodontic treatment. The purpose of this article is to review the principles of case management of soft tissue impacted second premolars mandibular and to illustrate their potential to respond well to the treatment. Although the scope of treatment may depend on a varying range of factors, this case report demonstrates the inherent potential for good treatment outcome in cases of soft tissue impactions.
Mandibular Third Molar Surgery in Patients with Oral Submucous Fibrosis: Mana...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Prevalence of Impacted Mandibular Third Molars in Population of Arab Israel...Abu-Hussein Muhamad
Abstract:
Introduction: Impaction may be defined as the failure of complete eruption into a normal functional position of one tooth within normal time due to lack of space in the dental arch, caused by obstruction by another tooth or development in an abnormal position. The mandibular third molar is the most frequently impacted tooth. The incidence varies from 9.5% to 68% in different populations.
Methods: The study was conducted in Center for Dentistry Research and Aesthetics, Jatt, Israel .Study represents retrospective analysis of panoramic radiographs (orthopantomograms) of patients referred to Center for Dentistry Research and Aesthetics, Jatt, Israel from January 2006 to December 2015 .
Results: A total of 1076 patients,649(60,3%) males ,and 427 (39,7%) females visited Center for Dentistry Research and Aesthetics, Jatt, Israel between January2006 and December2015. . A total of 206 patients met the inclusion criteria. The age ranged from 17 to 55years, with a mean age of 28.1 years and the standard deviation was 5.8 years.The prevalence of impacted mandibular third molars for this study was 19,2%.
Conclusion: This study demonstrated that males (62,2%) were more likely to present with impacted mandibular third molars than females (37,8%). The prevalence of third molar impactions was almost the same on both the left (47.8%) and right (52,2%) sides. This study also noted that mesio-angular impactions (50%) were the most common type of impaction. The least common form of impactions was the inverted types (0.3%). The prevalence of impacted mandibular third molars for this study was 19,2%.
Keywords: impacted mandibular third molars, incidence,Arab Israeli(Arab48)
The purpose of this article is to review the principles of case management of soft tissue impacted second premolars mandibular and to illustrate their potential to respond well to the treatment. Although the scope of treatment may depend on a varying range of factors, this case report demonstrates the inherent potential for good treatment outcome in cases of soft tissue impactions
The mandibular second premolar is one of the most frequently impacted teeth. The recommended treatment is to extract the second primary molar with or without removing the bone along the eruption path, to uncover the tooth surgically and move it into the arch by orthodontic treatment. The purpose of this article is to review the principles of case management of soft tissue impacted second premolars mandibular and to illustrate their potential to respond well to the treatment. Although the scope of treatment may depend on a varying range of factors, this case report demonstrates the inherent potential for good treatment outcome in cases of soft tissue impactions.
The mandibular second premolar is one of the most frequently impacted teeth. The recommended treatment is to extract the second primary molar with or without removing the bone along the eruption path, to uncover the tooth surgically and move it into the arch by orthodontic treatment.
The purpose of this article is to review the principles of case management of soft tissue impacted second premolars mandibular and to illustrate their potential to respond well to the treatment. Although the scope of treatment may depend on a varying range of factors, this case report demonstrates the inherent potential for good treatment outcome in cases of soft tissue impactions
Introduction: Impaction of maxillary canines is a frequently encountered clinical problem in orthodontic therapy. When a preventive approach fails, treatment involves surgical exposure of the impacted tooth, followed by orthodontic traction to guide and align it into the dental arch. The aim of the present report was to demonstrate by case reports of an adult patient with bilateral impacted maxillary canines treated with surgical exposure and orthodontic treatment
Mandibular Third Molar Surgery in Patients with Oral Submucous Fibrosis: Mana...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Prevalence of Impacted Mandibular Third Molars in Population of Arab Israel...Abu-Hussein Muhamad
Abstract:
Introduction: Impaction may be defined as the failure of complete eruption into a normal functional position of one tooth within normal time due to lack of space in the dental arch, caused by obstruction by another tooth or development in an abnormal position. The mandibular third molar is the most frequently impacted tooth. The incidence varies from 9.5% to 68% in different populations.
Methods: The study was conducted in Center for Dentistry Research and Aesthetics, Jatt, Israel .Study represents retrospective analysis of panoramic radiographs (orthopantomograms) of patients referred to Center for Dentistry Research and Aesthetics, Jatt, Israel from January 2006 to December 2015 .
Results: A total of 1076 patients,649(60,3%) males ,and 427 (39,7%) females visited Center for Dentistry Research and Aesthetics, Jatt, Israel between January2006 and December2015. . A total of 206 patients met the inclusion criteria. The age ranged from 17 to 55years, with a mean age of 28.1 years and the standard deviation was 5.8 years.The prevalence of impacted mandibular third molars for this study was 19,2%.
Conclusion: This study demonstrated that males (62,2%) were more likely to present with impacted mandibular third molars than females (37,8%). The prevalence of third molar impactions was almost the same on both the left (47.8%) and right (52,2%) sides. This study also noted that mesio-angular impactions (50%) were the most common type of impaction. The least common form of impactions was the inverted types (0.3%). The prevalence of impacted mandibular third molars for this study was 19,2%.
Keywords: impacted mandibular third molars, incidence,Arab Israeli(Arab48)
The purpose of this article is to review the principles of case management of soft tissue impacted second premolars mandibular and to illustrate their potential to respond well to the treatment. Although the scope of treatment may depend on a varying range of factors, this case report demonstrates the inherent potential for good treatment outcome in cases of soft tissue impactions
The mandibular second premolar is one of the most frequently impacted teeth. The recommended treatment is to extract the second primary molar with or without removing the bone along the eruption path, to uncover the tooth surgically and move it into the arch by orthodontic treatment. The purpose of this article is to review the principles of case management of soft tissue impacted second premolars mandibular and to illustrate their potential to respond well to the treatment. Although the scope of treatment may depend on a varying range of factors, this case report demonstrates the inherent potential for good treatment outcome in cases of soft tissue impactions.
The mandibular second premolar is one of the most frequently impacted teeth. The recommended treatment is to extract the second primary molar with or without removing the bone along the eruption path, to uncover the tooth surgically and move it into the arch by orthodontic treatment.
The purpose of this article is to review the principles of case management of soft tissue impacted second premolars mandibular and to illustrate their potential to respond well to the treatment. Although the scope of treatment may depend on a varying range of factors, this case report demonstrates the inherent potential for good treatment outcome in cases of soft tissue impactions
Introduction: Impaction of maxillary canines is a frequently encountered clinical problem in orthodontic therapy. When a preventive approach fails, treatment involves surgical exposure of the impacted tooth, followed by orthodontic traction to guide and align it into the dental arch. The aim of the present report was to demonstrate by case reports of an adult patient with bilateral impacted maxillary canines treated with surgical exposure and orthodontic treatment
Introduction: Impaction of maxillary canines is a frequently encountered clinical problem in orthodontic therapy. When a preventive approach fails, treatment involves surgical exposure of the impacted tooth, followed by orthodontic traction to guide and align it into the dental arch. The aim of the present report was to demonstrate by case reports of an adult patient with bilateral impacted maxillary canines treated with surgical exposure and orthodontic treatment.
Clinical Management of Bilateral Impacted Maxillary CaninesAbu-Hussein Muhamad
Introduction: Impaction of maxillary canines is a frequently encountered clinical problem in orthodontic therapy. When a preventive
approach fails, treatment involves surgical exposure of the impacted tooth, followed by orthodontic traction to guide and align it into the
dental arch. The aim of the present report was to demonstrate by case reports of an adult patient with bilateral impacted maxillary canines
treated with surgical exposure and orthodontic treatment.
Material and Methods: A 15year-old female with various degrees of bilateral palatal impaction of maxillary canines were managed
by the described technique.
Results and Discussion: Autonomous eruption of the impacted canines after surgical uncovering was witnessed in all patients
without the need for application of a vertical orthodontic force for their extrusion.
Conclusion: The described method of surgical uncovering and autonomous eruption created conditions for biological eruption of the
palatally impacted canines into the oral cavity and facilitated considerably the subsequent orthodontic treatment for their proper alignment
in the dental arch.
Keywords: Impacted canines; Surgical; Tooth exposure; Orthodontic treatment
Titanium Button With Chain by Watted For Orthodontic Traction of Impacted Ma...Abu-Hussein Muhamad
Abstract: Advances in bonding techniques and materials allow for reliable bracket placement on ectopically positioned teeth. This prospective study evaluates the outcome of forced orthodontic eruption of impacted canine teeth in both palatal and labial positions. Eighty-two impacted maxillary canines in 2200patients were included in the study and were observed for 2006 to 2013 ,in Center for Dentistry research and Aesthetics, Jatt/Israel after exposure. Following exposure by means of a palatal flap or an apically repositioned buccal flap, an orthodontic traction hook, with a Titanium Button with chain by Watted (Dentaurum) attached, was bonded to each impacted tooth using a light cured orthodontic resin cement. A periodontal dressing was placed over the surgical site for a period of time. All teeth were successfully erupted. Complications consisted of: failure of initial bond, at the time of surgery, which required rebonding; premature debonding at the time of pack removal and; debonding of brackets during orthodontic eruption. There was no infection, eruption failure, ankylosis, resorption or periodontal defect (pocket greater than 3 mm) associated with any of the exposed teeth. Forced orthodontic eruption of impacted maxillary canines with a well bonded orthodontic traction hook and ligation chain, used in conjunction with a palatal flap or an apically repositioned labial flap, results in predictable orthodontic eruption with few complications. Key Words: cuspid/surgery; orthodontics, corrective; tooth, impacted/therapy
Root Resection – A Dark Horse in Management Offurcation Involved Maxillary Mo...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Treatment concept by Watted for a controlled alignment of palatally impacted ...Abu-Hussein Muhamad
It is known that maxillary canines remain impacted more often than the mandibular canines, and the inclusion can be
buccal or palatal. The treatment focuses mainly on the exposure and on the orthodontic realignment of the impacted
tooth. There are situations when canines erupt spontaneously after their surgical discovery. The present paper has the
purpose of approaching aspects related to impacted upper permanent canines by a literature review, including
localization and treatment conducts.
Key words: Impacted canine, periodontal, surgical-orthodontic treatment.
Endodontic Management of Unusual Case of Type II Dens Invaginatus – A Case Re...QUESTJOURNAL
ABSTRACT: A thorough knowledge of the normal anatomy of the root canal system as well as the possible aberrancies is imperative for success of endodontic therapy .The challenge lies in diagnosing these conditions properly, complete debridement of the root canal system, and 3-dimensional sealing of the same. Morphological dental anomalies of the maxillary lateral incisors are relatively common . Endodontic treatment for teeth that exhibit the dental anomaly, dens invaginatus, can be difficult due to the bizarre anatomy and relative inaccessibility of the diseased pulp tissue. Dens invaginatus is a developmental malformation of teeth. Affected teeth show a deep infolding of enamel and dentine starting from the foramen caecum or even the tip of the cusps and which may extend deep into the root. . The malformation shows a broad spectrum of morphologic variations and frequently results in early pulp necrosis. Dens invaginatus is a critical condition for endodontic treatment once it frequently presents a complex internal anatomy and might be associated with incomplete root and apical development. Therefore every effort must be made to identify and diagnose the variation. This article presents an Unusual case of Endodontic Management of maxillary left lateral incisior with Type II Dens Invaginatus .
Detailed description on management of impacted maxillary and mandibular third molars. Surgical approaches and complications are also discussed in details.
24.Rahul VC Tiwari et al. Role of maxillary third molar in le fort I orthognathic surgery: A mini review & case report - International Journal of Applied Dental Sciences 2018; 4(4): 280-281.
20.Rahul VC Tiwari et al. Craniofacial trauma of 3-year-old child–Acritical case report. Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology, July-September, 2018;4(3):173-174
Similar to 32nd publication ijohmr - 2nd name (20)
60.Srinivasan S, Velusamy G, Munshi MAI, Radhakrishnan K, Tiwari RVC. Comparative Study of Antifungal Efficacy of Various Endodontic Irrigants with and without Clotrimazole in Extracted Teeth Inoculated with Candida albicans. J Contemp Dent Pract. 2020 Dec 1;21(12):1325-1330. PubMed PMID: 33893253.
Mathew P, Kattimani VS, Tiwari RV, Iqbal MS, Tabassum A, Syed KG. New Classification System for Cleft Alveolus: A Computed Tomography-based Appraisal. J Contemp Dent Pract. 2020 Aug 1;21(8):942-948. PubMed PMID: 33568619
Sahu S, Patley A, Kharsan V, Madan RS, Manjula V, Tiwari RVC. Comparative evaluation of efficacy and latency of twin mix vs 2% lignocaine HCL with 1:80000 epinephrine in surgical removal of impacted mandibular third molar. J Family Med Prim Care. 2020 Feb;9(2):904-908. doi: 10.4103/jfmpc.jfmpc_998_19. eCollection 2020 Feb. PubMed PMID: 32318443; PubMed Central PMCID: PMC7113948.
65.Izna, Sasank Kuntamukkula VK, Khanna SS, Salokhe O, Chandra Tiwari RV, Tiwari H. Knowledge and Apprehension of Dental Health Professionals Pertaining to COVID in Southern India: A Questionnaire Study. J Pharm Bioallied Sci. 2021 Jun;13(Suppl 1):S448-S451. doi: 10.4103/jpbs.JPBS_551_20. Epub 2021 Jun 5. PubMed PMID: 34447131; PubMed Central PMCID: PMC8375944.
Vohra P, Belkhode V, Nimonkar S, Potdar S, Bhanot R, Izna, Tiwari RVC. Evaluation and diagnostic usefulness of saliva for detection of HIV antibodies: A cross-sectional study. J Family Med Prim Care. 2020 May;9(5):2437-2441. doi: 10.4103/jfmpc.jfmpc_138_20. eCollection 2020 May. PubMed PMID: 32754516; PubMed Central PMCID: PMC7380795
Mittal S, Hussain SA, Tiwari RVC, Poovathingal AB, Priya BP, Bhanot R, Tiwari H. Extensive pelvic and abdominal lymphadenopathy with hepatosplenomegaly treated with radiotherapy-A case report. J Family Med Prim Care. 2020 Feb;9(2):1215-1218. doi: 10.4103/jfmpc.jfmpc_1125_19. eCollection 2020 Feb. PubMed PMID: 32318498; PubMed Central PMCID: PMC7113973.
36.Kesharwani P, Hussain SA, Sharma N, Karpathak S, Bhanot R, Kothari S, Tiwari RVC. Massive radicular cyst involving multiple teeth in pediatric mandible- A case report. J Family Med Prim Care. 2020 Feb;9(2):1253-1256. doi: 10.4103/jfmpc.jfmpc_1059_19. eCollection 2020 Feb. PubMed PMID: 32318508; PubMed Central PMCID: PMC7113959.
More from CLOVE Dental OMNI Hospitals Andhra Hospital (20)
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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32nd publication ijohmr - 2nd name
1. International Journal of Oral Health and Medical Research | ISSN 2395-7387 | JANUARY-FEBRUARY 2018 | VOL 4 | ISSUE 5 51
CASE REPORTMathew P et al.: Ectopic Eruption of Supernumerary Mandibular Molar
Correspondence to:
Dr. Philip Mathew, Department of Oral &
Maxillofacial Surgery and Dentistry, Jubilee
Mission Medical College Hospital and Research
Institute, Kerala, India
Contact Us: www.ijohmr.com
An unusual case of Ectopic Eruption of
Supernumerary Mandibular Molar tooth in
Coronoid
Philip Mathew1
, Rahul VC Tiwari2
, Aswin Mullath3
, Jisha David4
, Heena Tiwari5
Ectopic eruption of teeth in the oral cavity is a common phenomenon noticed by clinicians in a day to day practice.
Various etiologic factors are involved for the same reason. The unusual presentation of teeth can be present in jaw bone
or in other associated structures. Published literature also report such cases. Impacted tooth sequela to pathology. We
are presenting a case report of ectopic eruption of the supernumerary mandibular molar tooth in coronoid.
KEYWORDS: Impacted tooth, Ectopic eruption, Molar tooth, Coronoid
AASSSAAsasasss
Ectopic essentially signifies "the wrong position." The
nearness of an ectopic molar might be the consequence of
formative aggravations (ectopic eruption, impaction, or
ankylosis), pathologic procedures (dislodged by cyst), or
iatrogenic movement. The ectopic eruption, which
implies eruption into the wrong place, is well on the way
to happen in the eruption of maxillary first molars
furthermore, mandibular lateral incisors.1,2
Treatment of
such tooth is removal. If no indications or pathology is
clear, perception might be the treatment of decision.
Intercession comprises of a concise time of orthodontic
treatment or the evacuation of teeth (essential or
changeless) with the endeavor to dispense with tooth
impaction. For ectopic first or second molars, a joined
orthodontic-surgical approach ought to dependably be
considered to permit eruption into ordinary position.
Migration needs repositioning of an ectopic tooth
surgically or orthodontically.3
The point of intercession
or movement is to keep up the respectability of the curve
and impediment. In any case, extraction ought to be
considered if the above measures are considered
outlandish, or the tooth is symptomatic or is related to
pathologies such as ankylosis or cystic changes. There
have been reports of an ectopic molar tooth in the
maxillary sinus4,5
and in condylar region forming a
dentigerous cysts.6–9
The present report portrays an uncommon case of an
ectopic molar average to the coronoid process of
mandible leading to pathology. Published literature has
given data regarding ectopic eruptions their position and
approaches for surgical removal (Table 1).
The etiology of ectopic eruption is still a mystery, and
many theories have been suggested, including trauma,
infection, cyst, tumor, crowding, and developmental
abnormalities. In many cases, however, the etiology
cannot be identified.10
Mostly, the etiology is associated
with tooth and its immediate anatomic environment. In
the present case, the origin of the tooth is controversial. It
may be either a mandibular molar that migrated during
development or an iatrogenically displaced maxillary
molar. This is a case report of a 46-year-old male who
presented with a complaint of pain and swelling and
How to cite this article:
Mathew P, Rahul VCT, Mullath A, David J, Tiwari H. An unusual case of Ectopic Eruption of Supernumerary Mandibular Molar tooth in Coronoid. Int J
Oral Health Med Res 2017;4(5):51-54.
INTRODUCTION
1,2,4-Department of Oral & Maxillofacial Surgery and Dentistry, Jubilee Mission
Medical College Hospital and Research Institute, Thrissur, Kerala, India. 3-PG Student,
Department of Oral & Maxillofacial Surgery, KMCT Dental College, Calicut, Kerala,
India. 5-Department of Dentistry, Government Dental Surgeon, CHC Makdi,
Kondgaon, Chhattisgarh, India.
ABSTRACT
CASE REPORT
Table 1: Ectopic third molars in literature
2. International Journal of Oral Health and Medical Research | ISSN 2395-7387 | JANUARY-FEBRUARY 2018 | VOL 4 | ISSUE 5 52
CASE REPORTMathew P et al.: Ectopic Eruption of Supernumerary Mandibular Molar
difficulty in mouth opening. On clinical examination,
there was intraoral swelling on the left side. It was also
persistent in extra oral region. The periodontal health was
compromised. Patient also gives a history of extraction
and uneventful healing with maxillary left third molar.
Orthopantomogram was advised which showed bilateral
impacted supernumerary tooth was present (Figure 1). In
the right side, it was present on ramus of mandible
involving the inferior alveolar nerve. Tooth was
incompletely formed according to its normal anatomical
structure. On left side the supernumerary tooth was
present on coronoid process of mandible forming
radiolucent mass extending into ramus of mandible
involving crown of supernumerary tooth.
Clinicoradiographically it was diagnosed as dentigerous
cyst. All the required pre-operative hematological
investigations, chest X ray, electrocardiogram was
obtained and surgical removal of impacted tooth was
planned under general anesthesia. Intravenous antibiotics,
analgesics and anti-inflammatory drugs were given
before the procedure as prophylaxis. Intra oral approach
was preferred using vertical incision extending distally to
third molar towards external oblique ridge reaching the
anterior border of ramus and coronoid was given. Tissue
was reflected and lesion was exposed (Figure 2).
Removal of infected mass was performed and impacted
tooth was exposed in oral cavity (Figure 3). The
supernumerary tooth was surgically removed (Figure 4).
Surgical closure was done using 4-0 vicryl absorbable
sutures. Postoperative instructions and medication was
prescribed.
Ectopic teeth are located in the jawbones or regions other
than the alveolar arch. Ectopic eruption of a tooth is rare;
however, there have been few reports of tooth in the nose,
mandibular condylary and coronoid processes and
maxillary sinus.11-14
Most of the cases in the mandibular
coronoid and condylary regions had symptomatic signs;
common symptoms of the clinical examination were pain,
trismus, swelling, and temporomandibular joint problems.
On the other hand, ectopic teeths are often discovered in
routine clinical or radiographic examinations; as some of
the cases were asymptomatic, like the case study above.
The aetiology of ectopic eruption is still unclear, and
reaches have suggested many theories, including trauma,
infection, pathologic conditions, crowding and develop
mental anomalies. However, it is likely to be an ectopic
mandibular third molar for the following reasons: (1) the
sinus discharge is in the mandible; (2) a pericoronal
radiolucency can be seen around the crown; (3) if the root
was located within the bony part of the coronoid process;
absence of severe trismus after the maxillary molar
extraction, and (5) an iatrogenically displaced maxillary
third molar is usually positioned distal to the posterior
maxillary wall and higher up in the infratemporal fossa.
Figure 1: Orthopantomogram showing a mandibular third molar
tooth present in Chondroid region of mandible.
Figure 2:Incision and Exposure of Lesion
Figure 3:Impacted mandibular third molar in the choronoid
region of mandible.
Figure 4:Extracted tooth
DISCUSSION
3. International Journal of Oral Health and Medical Research | ISSN 2395-7387 | JANUARY-FEBRUARY 2018 | VOL 4 | ISSUE 5 53
CASE REPORTMathew P et al.: Ectopic Eruption of Supernumerary Mandibular Molar
Odontogenesis is a complex process, and abnormal tissue
interactions between the oral epithelium and the
underlying mesenchymal tissue during development may
potentially result in ectopic tooth development and
eruption.15
A mandibular third molar may be displaced by
a lesion such as a cyst or a tumor.16
The displacement of
tooth buds by the expansion of progressively growing
dentigerous cysts may result in the displacement of the
tooth to other areas. In some of the reports in the
literature review, the cysts associated with the ectopic
third molars were very small like our case. Such cysts
may have once occupied the entire ramus, but their walls
may have been perforated, which resulted in drainage and
decompression.16,17
This pathological process may
support the idea that a dentigerous cyst was the etiologic
factor of ectopic eruption in the subject of our case. For
ectopic mandibular third molars associated with the
condylar process of the mandible, various approaches
have been used to gain access for retrieval of the tooth.
Szerlip reported an ectopic third molar in the condylar
process removed by an intraoral approach.18
Bux and
Lisco reported a third molar associated with a dentigerous
cyst in the subcondylar region and approached it through
a cutaneous incision below the mandibular angle
followed by a submasseteric dissection to create a
subperiosteal tunnel leading to the surgical site.19
Tumer
et al reported a third molar and a cyst in a similar position
and excised them through a preauricular approach.20
Recently, Suarez-Cunqueiro et al used an endoscopic
approach to remove an ectopic mandibular third molar in
the condylar process and claimed advantages such as
good illumination, clear and magnified visualization of
the operating field, and more conservative surgery.21
Possible risk of damage to the facial nerve and scars on
the skin could also be avoided with an endoscopic
approach.22
They therefore advocated that endoscopy be
used to remove ectopic third molars, not only in the
condylar process but also in other ectopic locations, such
as the maxillary sinus and nasal fossa. However, adequate
training beforehand is essential. In this case, a pure
intraoral approach was sufficient since the coronoid
process is accessible via a wide incision along the
ascending ramus. Adequate isolation was achieved by
placing a sigmoid notch retractor buccally in the sigmoid
notch, a Kocher artery forceps clamping the tip of the
coronoid process, a channel retractor, and a periosteal
elevator medially distal to the tooth. In this way, further
displacement distally during manipulation was prevented.
A coronoidectomy could be considered in case of
inadequate access but was found to be unnecessary.
Unusual presentation of impacted or ectopic tooth is a
common phenomenon, but the presence of an ectopic
supernumerary molar on coronoid process of mandible
tooth is rare. In such condition the tooth is also associated
with pathology and infection, surgical removal of tooth is
indicated under proper antibiotic coverage and pre-
operative hematological and radiological investigations.
We acknowledge Doctors of Department of Oral and
Maxillofacial Surgery, Department of Emergency
Medicine and Department of Radiodiagnosis of Jubilee
Mission Medical College Hospital and Research Centre
for their help and support.
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maxillary first permanent molar: Etiologic factors.
Am J Orthod 1983;84:147–155.
2. Shapira Y, Kuftinec MM. The ectopically erupted
mandibular lateral incisor. Am J Orthod 1982;82:
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3. Frank CA. Treatment options for impacted teeth. J
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4. Goh YH. Ectopic eruption of maxillary molar
tooth—An unusual cause of recurrent sinusitis.
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Ectopic eruption of a maxillary third molar tooth in
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Pract 2005;6:104–110.
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cyst—An unusual case.J Oral Surg 1978;36:551–
552.
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a dentigerous cyst in the subcondylar region: Report
of case. J Oral Maxillofac Surg 1994;52:630–632.
8. Tumer C, Eset AE, Atabek A. Ectopic impacted
mandibular third molar in the subcondylar region
associated with a dentigerous cyst: A case report.
Quintessence Int 2002;33:231–233.
9. Suarez-Cunqueiro MM, Schoen R, Schramm A,
Gellrich NC, Schmelzeisen R. Endoscopic approach
to removal of an ectopic mandibular third molar. Br J
Oral Maxillofac Surg 2003;41:340–342.
10. Debes RR, Miller SB. Molar in coronoid process.
Oral Surg Oral Med Oral Pathol 1969;28:511.
11. Iglesias-Martin F, Infante-Cossio P, Torres-Carranza
E, Prats-Golczer VE, Garcia-Perla-Garcia A. Ectopic
third molar in the mandibular condyle: a review of
the literature. Med Oral Patol Oral Cir Bucal.
2012;17:e1013-7.
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Ectopic mandibular third molar leading to
osteomyelitis of condyle: a case report with literature
review. Oral Maxillofac Surg. 2013;17:127-30.
13. Baykul T, Doğru H, Yasan H, Cina Aksoy M.
Clinical impact of ectopic teeth in the maxillary
sinus. Auris Nasus Larynx. 2006;33:277- 81.
14. Verma RK, Bakshi J, Panda NK. Ectopic intranasal
tooth: an unusual cause of epistaxis in a child. Ear
Nose Throat J. 2012;91:242-4.
15. Srinivasa Prasad T, Sujatha G, Niazi T, Rajesh P.
Dentigerous cyst associated with an ectopic third
molar in the maxillary sinus: A rare entity. Indian J
Dent Res. 2007;18:141-3
CONCLUSION
ACKNOWLEDGEMENT
REFERENCES
4. International Journal of Oral Health and Medical Research | ISSN 2395-7387 | JANUARY-FEBRUARY 2018 | VOL 4 | ISSUE 5 54
CASE REPORTMathew P et al.: Ectopic Eruption of Supernumerary Mandibular Molar
16. Medici A, Raho MT, Anghinoni M. Ectopic third
molar in the condylar process: case report. Acta
Biomed Ateneo Parmense. 2001;72:115-8.
17. Bux P, Lisco V. Ectopic third molar associated with
a dentigerous cyst in the subcondylar region: report
of case. J Oral Maxillofac Surg. 1994;52:630-2.
18. Szerlip L. Displaced third molar with dentigerous
cyst—An unusual case.J Oral Surg 1978;36:551–
552.
19. Bux P, Lisco V. Ectopic third molar associated with
a dentigerous cyst in the subcondylar region: Report
of case. J Oral Maxillofac Surg 1994;52:630–632.
20. Tumer C, Eset AE, Atabek A. Ectopic impacted
mandibular third molar in the subcondylar region
associated with a dentigerous cyst: A case report.
Quintessence Int 2002;33:231–233.
21. Suarez-Cunqueiro MM, Schoen R, Schramm A,
Gellrich NC, Schmelzeisen R. Endoscopic approach
to removal of an ectopic mandibular third molar. Br J
Oral Maxillofac Surg 2003;41:340–342.
22. Debes RR, Miller SB. Molar in coronoid process.
Oral Surg Oral Med Oral Pathol 1969;28:511.
Source of Support: Nil
Conflict of Interest: Nil