29.macrolide

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Dr.Manish Kumar

Macrolides are a class of antibiotics that includes erythromycin, roxithromycin, clarithromycin and azithromycin. They work by inhibiting bacterial protein synthesis. They are used to treat atypical pneumonia caused by mycoplasma pneumoniae, whooping cough, streptococcal infections and diphtheria and tetanus. Common side effects of erythromycin include epigastric pain, hearing impairment, rashes, hepatitis and jaundice.

Health & Medicine

Macrolides

Examples
• Erythromycin
• Roxithromycin
• Clarithromycin
• Azithromycin

Mechanism of action
• Inhibit bacterial protein synthesis

Uses
• Atypical pneumonia caused by
mycoplasma pneumoniae
• Whooping cough
• Steptococcal pharyngitis, tonsillitis
• Diphtheria, tetanus

Adverse effects of erythromycin
• Epigastric pain, hearing impairment,
rashes, hepatitis, jaundice

Adverse effects of erythromycin
• Epigastric pain, hearing impairment,
rashes, hepatitis, jaundice

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29.macrolide

2. Examples • Erythromycin • Roxithromycin • Clarithromycin • Azithromycin

3. Mechanism of action • Inhibit bacterial protein synthesis

4. Uses • Atypical pneumonia caused by mycoplasma pneumoniae • Whooping cough • Steptococcal pharyngitis, tonsillitis • Diphtheria, tetanus

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6. Adverse effects of erythromycin • Epigastric pain, hearing impairment, rashes, hepatitis, jaundice