機械学習の社会実装では、予測精度が高くても、機械学習がブラックボックであるために使うことができないということがよく起きます。
このスライドでは機械学習が不得意な予測結果の根拠を示すために考案されたLIMEの論文を解説します。
Ribeiro, Marco Tulio, Sameer Singh, and Carlos Guestrin. "" Why should i trust you?" Explaining the predictions of any classifier." Proceedings of the 22nd ACM SIGKDD international conference on knowledge discovery and data mining. 2016.
機械学習の社会実装では、予測精度が高くても、機械学習がブラックボックであるために使うことができないということがよく起きます。
このスライドでは機械学習が不得意な予測結果の根拠を示すために考案されたLIMEの論文を解説します。
Ribeiro, Marco Tulio, Sameer Singh, and Carlos Guestrin. "" Why should i trust you?" Explaining the predictions of any classifier." Proceedings of the 22nd ACM SIGKDD international conference on knowledge discovery and data mining. 2016.
Entwicklungen in Spielen als Innovationstreiber für UsabilityMichael Jendryschik
Die Geschichte der Spieleentwicklung zeigt sehr kurze Innovationszyklen im Bereich von Usability und HMI, sowohl im Hard- als auch im Softwarebereich. Von diesen Entwicklungen können auch industrielle HMI-Konzepte profitieren: „Game inspired HMI Design“ steigert unter anderem die Individualisierbarkeit und die Lernförderlichkeit von HMIs und damit die Motivation und Arbeitsqualität der Nutzer.
Warum muss Software weiterentwickelt werden? Was sind die Herausforderungen eines Modernisierungsprojektes? Was sind Vorteil und Nutzen der modellbasierten Migration?
Gemeinsam kreativ für bessere Software - Vortragsreihe Dortmunditemis AG
Wie gehören Software und Kreativität zusammen? Was ist Kreativität? Der Softwareentwicklungsprozess: Iteration und Exploration. Methodenüberblick anhand von zwei Beispielen: Affinity Diagramming und Paper Prototyping.
The Graphiti framework is a new approach to create highly sophisticated visual editors on top of the GEF framework. Graphiti can easily be integrated with EMF as the domain modeling framework. The creation of visual editors is done in Java, programming against the Graphiti framework API. It is fairly simple, but yet repetitive, which makes it a candidate to be supported by the means of model-driven development.
Spray aims to provide Domain Specific Languages (DSL) (implemented with Xtext) to describe Visual DSL Editors against the Graphiti runtime, and provide code generation (implemented with Xtend) to create the boilerplate code for realizing the implementation against the Graphiti framework. Potentially the Spray DSL can be used to generate code for other graphical editor frameworks as well, although it is not the primary focus of the project now.
The generated code is structured in such a way that one can always extend/overwrite the generated code with handwritten Java to add advanced Graphiti features that are not supported directly by the Spray DSL. Therefore Spray makes use of the "Generation Gap Pattern".
With the help of the tools created with Spray, Graphiti based diagram editors can be created much faster and reliable than doing it purely by hand.
Using JIRA and Confluence to support ITIL like processesjoergreichert
Standards like ITIL define processes how to handle incoming inquiries, bug reports and change requests. This presentation shows some hints how to use and customize JIRA and Confluence to support such processes.
A Large-Scale Study of Test Coverage Evolutionjon_bell
While it is common for projects to measure what percentage of their statements are executed by tests, this single number is woefully inadequate at providing a detailed understanding of the extent to which a project’s code is tested, if there are gaps in the tests, and if these tests are useful in any meaningful way. For instance, seemingly simple changes in one part of the codebase may reduce the efficacy of existing tests that seem otherwise unrelated.
Code coverage can be useful to track long-term trends in how tested a project is, but on a day-to-day basis, can’t serve as an indicator for the change in test suite quality. In particular, moving the coverage needle even 0.01% can be extremely difficult in a project with millions of lines of code. At such a large scale, focus often drifts from which lines of code are covered to simply the number of lines covered. However, a change in the coverage of several hundred critical lines of code might be important for developers to take notice of. Over time, these small changes to which lines are covered add up to form a coverage debt, and can lead to a dangerous reduction in test suite effectiveness.
We are building tools and techniques to help every developer track and manage their coverage debt, easily answering questions like: Which lines are no longer covered, even though I didn’t change them? Which lines are non-deterministically covered, perhaps indicative of flaky tests? By answering these questions with hard data, we can provide developers with a rich understanding of the impact of their actions on test suite effectiveness.
Von der Nutzungsanforderung zur formalen Softwarespezifikationitemis AG
Welche Bedeutung haben klare Anforderungen für den Projekterfolg? Was sind Nutzungsanforderungen und Systemanforderungen? Was gehört zur Anforderungsspezifikation/zum Anforderungsmanagement? Modellierung mit dem Werkzeug YAKINDU Requirements
PERSONAL DEVELOPMENT CENTERS & THOUGHT LEADERS - brand research foxtheory
1. Wellness Center Trends
2. Wellness Centers Around The World - SWOT Analysis
- Sivananda Ashram, Bahamas
- Como, Bali
- Maya, Tulum
- Omega Institute
- Canyon Ranch
- Aqua Wellness
- Asclepios
- Hotel Adler Thermae
- Sanctuary Retreat
- Haramara Retreat
Esalen
- San Ysidro Ranch
- Golden Door
- Aro Ha
- California Health
- Les Passeros
- Shreyas Retreat
3. New Education Systems
- Singularity University
- General Assembly
- AltMBA
4. Books
- 7 Habits of Highly Successful People
- How to Win Friends and influence people
- Untethered Soul
- The Obstacle is the way
- The One Thing
- Miracle Morning
- Hard Thing about Hard Things
- High Input Management
5. Forbes Top 10 Self Development Authors
6. Self-Development Websites and Podcasts
- Tim Ferriss Show
- MeaningfulMovement.com
7. Communities and Virtual Networks
- BurningMan
- Reddit
- WeWork
- Meetup.com
- Facebook
- Linkedin
8. Spiritual Leaders and Gurus
- Deepak Chopra
- Tony Robbins
- Stephen Covey
- Dale Carnegie
- Wayne Dyer
- Wunderlist
- Trello
- Nirvana
- Headspace
- Calm
- Pacifica
- ToDoist
10. Self Improvement Leaders and Seminars
- Tony Robbins
- Deepak Chopra
- Landmark Forum
- Jack Canfield
- Darren Hardy
- Maria Forleo
- Brendon Burchard
11. Concluding Thoughts
9. Life Management & Wellness Apps
- Evernote
- Charity Miles
- Wunderlist
- Trello
- Nirvana
- Headspace
- Calm
- Pacifica
- ToDoist
10. Self Improvement Leaders and Seminars
- Tony Robbins
- Deepak Chopra
- Landmark Forum
- Jack Canfield
- Darren Hardy
- Maria Forleo
- Brendon Burchard
11. Concluding Thoughts
Durch die stets wachsende Komplexität heutiger Systems Engineering Vorhaben wird der Bedarf an umfassender Transparenz immer größer. Traceability gewährleistet Transparenz durch den gesamten Entwicklungsprozess.
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Die Analyse und Spezifikation von Software-Anforderungen ist eine komplexe Aufgabe, die als Grundlage jedes Softwareentwicklungsprojekts für den späteren Erfolg oder Misserfolg maßgeblich ist. Oft bleiben jedoch Nutzungsanforderungen auf dem Weg zur Implementierung aufgrund einer mangelnden Integration in formale technische Spezifikationen auf der Strecke. Dieser Vortrag stellt einen werkzeugbasierten Ansatz zur Spezifikation komplexer interaktiver Systeme mit Hilfe des Werkzeugs YAKINDU Requirements vor.
Marketing B2B at Monterail — Szymon Boniecki, co-founder monterail
Inbound marketing for B2B services is different than for products.Your target group is small and the decision-making process takes months. Should marketing activity be focused on generating leads only? How to align marketing and sales? And how to start if you haven't yet?
The answers based on our marketing campaign that resulted in the contracts worth 3.2M PLN (750k EUR) — by Szymon Boniecki, Monterail co-founder.
Community dynamics of the adolescent vaginal microbiome during puberty (UOreg...Roxana Hickey
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Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
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Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.